ATE114051T1 - Verfahren zum nachweis von endotoxin. - Google Patents

Verfahren zum nachweis von endotoxin.

Info

Publication number
ATE114051T1
ATE114051T1 AT89103104T AT89103104T ATE114051T1 AT E114051 T1 ATE114051 T1 AT E114051T1 AT 89103104 T AT89103104 T AT 89103104T AT 89103104 T AT89103104 T AT 89103104T AT E114051 T1 ATE114051 T1 AT E114051T1
Authority
AT
Austria
Prior art keywords
procedure
endotoxin
detecting endotoxin
water
soluble polysaccharide
Prior art date
Application number
AT89103104T
Other languages
English (en)
Inventor
Shuji Matuura
Masakazu Tsuchiya
Original Assignee
Wako Pure Chem Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wako Pure Chem Ind Ltd filed Critical Wako Pure Chem Ind Ltd
Application granted granted Critical
Publication of ATE114051T1 publication Critical patent/ATE114051T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/24—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar beta-D-Glucans, i.e. having beta 1,n (n=3,4,6) linkages between saccharide units, e.g. xanthan

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • External Artificial Organs (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT89103104T 1988-02-27 1989-02-22 Verfahren zum nachweis von endotoxin. ATE114051T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63045069A JPH0715474B2 (ja) 1988-02-27 1988-02-27 エンドトキシンの測定法

Publications (1)

Publication Number Publication Date
ATE114051T1 true ATE114051T1 (de) 1994-11-15

Family

ID=12709059

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89103104T ATE114051T1 (de) 1988-02-27 1989-02-22 Verfahren zum nachweis von endotoxin.

Country Status (7)

Country Link
US (2) US5179006A (de)
EP (1) EP0330991B1 (de)
JP (1) JPH0715474B2 (de)
AT (1) ATE114051T1 (de)
CA (1) CA1339881C (de)
DE (1) DE68919245T2 (de)
ES (1) ES2065345T3 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0715474B2 (ja) * 1988-02-27 1995-02-22 和光純薬工業株式会社 エンドトキシンの測定法
US5594113A (en) * 1988-06-23 1997-01-14 Associates Of Cape Cod, Inc. Endotoxin binding and neutralizing protein and uses thereof
JP2547264B2 (ja) * 1988-09-01 1996-10-23 生化学工業株式会社 カブトガニ・アメボサイト・ライセートｇ因子活性化阻害剤
CA1328074C (en) * 1988-09-01 1994-03-29 Shigenori Tanaka Horseshoe crab amebocyte lysate factor g inhibitor
KR0141685B1 (ko) * 1988-09-01 1998-07-01 야마따니 와따루 참게 아메보사이트 라이세이트 g 인자 활성화 저해제
JP2944721B2 (ja) * 1990-08-22 1999-09-06 生化学工業株式会社 エンドトキシンの測定剤
DE69129365T2 (de) * 1990-08-22 1998-10-08 Seikagaku Kogyo K K Seikagaku Testagens für endotoxin
US5681710A (en) * 1991-03-14 1997-10-28 Seikagaku Kogyo Kabushiki Kaisha Reagent for determining (1→3)-β-D-glucan
CA2112776C (en) * 1993-01-21 2002-11-12 Masakazu Tsuchiya Process for inhibiting activity of endotoxin
JP3242733B2 (ja) * 1993-02-26 2001-12-25 生化学工業株式会社 エンドトキシン特異的測定剤
EP0669396B1 (de) * 1993-06-29 2008-05-07 Seikagaku Kogyo Kabushiki Kaisha Neuartige polypeptide und dafür kodierende dna
JP3429036B2 (ja) * 1993-09-30 2003-07-22 生化学工業株式会社 エンドトキシンの特異的測定剤
SG107124A1 (en) * 1994-08-19 2004-11-29 Univ Singapore Expression of carcinoscorpius rotundicauda factor c in eukaryotes
US5637474A (en) * 1994-10-31 1997-06-10 Wako Pure Chemical Industries, Ltd. Process for measuring amount of endotoxin or (1→3)-β-D-glucan by kinetic turbidimetric method
EP0837330B1 (de) 1996-10-21 2005-08-24 Seikagaku Corporation Verfahren zur Bestimmung von Endotoxin
US6270982B1 (en) 1997-10-09 2001-08-07 Charles River Laboratories Methods and compositions for the detection of bacterial endotoxins
EP0924220A3 (de) * 1997-12-16 2000-04-26 Wako Pure Chemical Industries, Ltd. Inhibitor für die Aktivierung eines Erkennungsproteins für beta-Glucan
US5998389A (en) * 1998-05-20 1999-12-07 Biowhitaker Technologies Endotoxin-specific assay
CN1081193C (zh) * 1998-07-15 2002-03-20 王利亚 羧甲基茯苓聚糖的合成方法
US7329538B2 (en) 2003-03-17 2008-02-12 Charles River Laboratories, Inc. Methods and compositions for the detection of microbial contaminants
US20050026239A1 (en) * 2003-04-18 2005-02-03 Associates Of Cape Cod, Inc. Kit for detecting endotoxin in aqueous solutions
US20050048655A1 (en) * 2003-04-18 2005-03-03 Novitsky Thomas J. Kit for detecting endotoxin
US7968280B2 (en) * 2004-12-02 2011-06-28 Charles River Laboratories, Inc. Methods for the detection and/or quantification of gram positive bacterial contaminants
DE602006004553D1 (de) * 2005-01-13 2009-02-12 Charles River Lab Inc Verfahren zur klassifizierung von mikroben in einer biologischen probe
US20110065911A1 (en) * 2008-02-19 2011-03-17 Novogen Research Pty Ltd Method for producing a bioactive glucan product substantially free of endotoxin contamination
JP5451649B2 (ja) * 2008-03-11 2014-03-26 フューチャー ファイバー テクノロジーズ ピーティーワイ リミテッド モダルメトリック・ファイバセンサ
WO2009137244A1 (en) * 2008-04-15 2009-11-12 Charles River Laboratories, Inc. Cartridge and method for sample analysis
CU24073B1 (es) 2011-12-27 2015-01-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS
CN102898533A (zh) * 2012-10-08 2013-01-30 湖北省宏源药业有限公司 一种羧甲基茯苓多糖的制备方法
CN109030486A (zh) * 2018-09-28 2018-12-18 润方（北京）生物医药研究院有限公司 一种血红蛋白样品的细菌内毒素检测方法
US12158471B2 (en) 2022-02-11 2024-12-03 Charles River Laboratories, Inc. Recombinant amebocyte lysate and uses thereof
CN121443750A (zh) 2023-06-05 2026-01-30 查尔斯河实验室公司 重组变形细胞凝血因子及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038029A (en) * 1976-01-20 1977-07-26 Worthington Biochemical Corporation Limulus lysate turbidity test for pyrogens
JPS5813516A (ja) * 1981-07-16 1983-01-26 Seikagaku Kogyo Co Ltd エンドトキシン特異性のカブトガニ・アメボサイト・ライゼート及びその製造方法
SE431228B (sv) * 1981-12-17 1984-01-23 Kenneth Soderhell Sett att bestemma bakteriella endotoxin medelst profenoloxidashaltigt blodkroppslysat fran kreftdjur eller insekter och reagens herfor
JPS5927828A (ja) * 1982-08-05 1984-02-14 Seikagaku Kogyo Co Ltd アメボサイト・ライゼートの調製方法
DE3586075D1 (de) * 1984-06-27 1992-06-25 Wako Pure Chem Ind Ltd Verfahren zur bestimmung von endotoxin.
JPH0715474B2 (ja) * 1988-02-27 1995-02-22 和光純薬工業株式会社 エンドトキシンの測定法
JPH0711523B2 (ja) * 1988-03-16 1995-02-08 和光純薬工業株式会社 試薬の調製方法
CA1328074C (en) * 1988-09-01 1994-03-29 Shigenori Tanaka Horseshoe crab amebocyte lysate factor g inhibitor

Also Published As

Publication number Publication date
US5179006A (en) 1993-01-12
EP0330991B1 (de) 1994-11-09
JPH0715474B2 (ja) 1995-02-22
ES2065345T3 (es) 1995-02-16
EP0330991A2 (de) 1989-09-06
DE68919245D1 (de) 1994-12-15
DE68919245T2 (de) 1995-05-18
JPH01219562A (ja) 1989-09-01
US5318893A (en) 1994-06-07
CA1339881C (en) 1998-05-26
EP0330991A3 (de) 1991-06-19

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