ES2065345T3 - Procedimiento para medir una endotoxina. - Google Patents

Procedimiento para medir una endotoxina.

Info

Publication number
ES2065345T3
ES2065345T3 ES89103104T ES89103104T ES2065345T3 ES 2065345 T3 ES2065345 T3 ES 2065345T3 ES 89103104 T ES89103104 T ES 89103104T ES 89103104 T ES89103104 T ES 89103104T ES 2065345 T3 ES2065345 T3 ES 2065345T3
Authority
ES
Spain
Prior art keywords
endotoxin
measuring
procedure
water
soluble polysaccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89103104T
Other languages
English (en)
Inventor
Shuji Matuura
Masakazu Tsuchiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Wako Pure Chemical Corp
Original Assignee
Wako Pure Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wako Pure Chemical Industries Ltd filed Critical Wako Pure Chemical Industries Ltd
Application granted granted Critical
Publication of ES2065345T3 publication Critical patent/ES2065345T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/24—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar beta-D-Glucans, i.e. having beta 1,n (n=3,4,6) linkages between saccharide units, e.g. xanthan

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

LA MEDICION DE LA ENDOTOXINA USANDO LA REACCION DE LISATA HEMOCITA DEL CANGREJO DE HERRADURA CON ENDOTOXINA EN UNA SOLUCION PUEDE SER REALIZADA EN PRESENCIA DE UN POLISACARIDO SOLUBLE EN AGUA CONTENIENDO UN ENLACE (BETA) - 1,3 GLUCOSIDICO Y/O UN DERIVADO POLISACARIDO SLUBLE EN AGUA CONTENIENDO UN ENLACE (BETA) - 1,3 GLUCOSIDICO.
ES89103104T 1988-02-27 1989-02-22 Procedimiento para medir una endotoxina. Expired - Lifetime ES2065345T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63045069A JPH0715474B2 (ja) 1988-02-27 1988-02-27 エンドトキシンの測定法

Publications (1)

Publication Number Publication Date
ES2065345T3 true ES2065345T3 (es) 1995-02-16

Family

ID=12709059

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89103104T Expired - Lifetime ES2065345T3 (es) 1988-02-27 1989-02-22 Procedimiento para medir una endotoxina.

Country Status (7)

Country Link
US (2) US5179006A (es)
EP (1) EP0330991B1 (es)
JP (1) JPH0715474B2 (es)
AT (1) ATE114051T1 (es)
CA (1) CA1339881C (es)
DE (1) DE68919245T2 (es)
ES (1) ES2065345T3 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0715474B2 (ja) * 1988-02-27 1995-02-22 和光純薬工業株式会社 エンドトキシンの測定法
US5594113A (en) * 1988-06-23 1997-01-14 Associates Of Cape Cod, Inc. Endotoxin binding and neutralizing protein and uses thereof
CA1328074C (en) * 1988-09-01 1994-03-29 Shigenori Tanaka Horseshoe crab amebocyte lysate factor g inhibitor
KR0141685B1 (ko) * 1988-09-01 1998-07-01 야마따니 와따루 참게 아메보사이트 라이세이트 g 인자 활성화 저해제
JP2547264B2 (ja) * 1988-09-01 1996-10-23 生化学工業株式会社 カブトガニ・アメボサイト・ライセートｇ因子活性化阻害剤
DE69129365T2 (de) * 1990-08-22 1998-10-08 Seikagaku Kogyo K K Seikagaku Testagens für endotoxin
JP2944721B2 (ja) * 1990-08-22 1999-09-06 生化学工業株式会社 エンドトキシンの測定剤
US5681710A (en) * 1991-03-14 1997-10-28 Seikagaku Kogyo Kabushiki Kaisha Reagent for determining (1→3)-β-D-glucan
CA2112776C (en) * 1993-01-21 2002-11-12 Masakazu Tsuchiya Process for inhibiting activity of endotoxin
JP3242733B2 (ja) * 1993-02-26 2001-12-25 生化学工業株式会社 エンドトキシン特異的測定剤
EP0669396B1 (en) * 1993-06-29 2008-05-07 Seikagaku Kogyo Kabushiki Kaisha Novel polypeptide and dna coding for the same
JP3429036B2 (ja) * 1993-09-30 2003-07-22 生化学工業株式会社 エンドトキシンの特異的測定剤
SG107124A1 (en) * 1994-08-19 2004-11-29 Univ Singapore Expression of carcinoscorpius rotundicauda factor c in eukaryotes
US5637474A (en) * 1994-10-31 1997-06-10 Wako Pure Chemical Industries, Ltd. Process for measuring amount of endotoxin or (1→3)-β-D-glucan by kinetic turbidimetric method
US6168924B1 (en) 1996-10-21 2001-01-02 Seikagaku Kogyo Kabushiki Kaisha Limulus reaction-activating substance, method for inactivating the substance and measuring its amount, and method for measuring limulus reaction
US6270982B1 (en) 1997-10-09 2001-08-07 Charles River Laboratories Methods and compositions for the detection of bacterial endotoxins
EP0924220A3 (en) * 1997-12-16 2000-04-26 Wako Pure Chemical Industries, Ltd. Inhibitor of the activation of beta-glucan recognition protein
US5998389A (en) * 1998-05-20 1999-12-07 Biowhitaker Technologies Endotoxin-specific assay
CN1081193C (zh) * 1998-07-15 2002-03-20 王利亚 羧甲基茯苓聚糖的合成方法
DE602004024769D1 (de) * 2003-03-17 2010-02-04 Charles River Lab Inc Methoden und zusammensetzungen für den nachweis mikrobieller verunreinigungen
WO2004094987A2 (en) * 2003-04-18 2004-11-04 Associates Of Cape Cod, Inc. Kit for detecting endotoxin in aqueous solutions
US20050048655A1 (en) * 2003-04-18 2005-03-03 Novitsky Thomas J. Kit for detecting endotoxin
JP2008522640A (ja) 2004-12-02 2008-07-03 チャールズ リバー ラボラトリーズ， インコーポレイテッド グラム陽性菌夾雑物の検出および／または定量化のための方法ならびに組成物
US7479375B2 (en) * 2005-01-13 2009-01-20 Charles River Laboratories, Inc. Method for classifying a microorganism in a biological sample
WO2009103114A1 (en) * 2008-02-19 2009-08-27 Novogen Research Pty Ltd Method for producing a bioactive glucan product substantially free of endotoxin contamination
EP2252636A4 (en) * 2008-03-11 2013-10-02 Future Fibre Tech Pty Ltd MODUSMETRIC FIBER SENSOR
US20090286692A1 (en) * 2008-04-15 2009-11-19 Wainwright Norman R Cartridge and Method for Sample Analysis
CU24073B1 (es) 2011-12-27 2015-01-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS
CN102898533A (zh) * 2012-10-08 2013-01-30 湖北省宏源药业有限公司 一种羧甲基茯苓多糖的制备方法
CN109030486A (zh) * 2018-09-28 2018-12-18 润方（北京）生物医药研究院有限公司 一种血红蛋白样品的细菌内毒素检测方法
US12158471B2 (en) 2022-02-11 2024-12-03 Charles River Laboratories, Inc. Recombinant amebocyte lysate and uses thereof
KR20260021702A (ko) 2023-06-05 2026-02-13 찰스리버레보레토리스,인코포레이티드 재조합 아메보사이트 응고 인자 및 그의 용도

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038029A (en) * 1976-01-20 1977-07-26 Worthington Biochemical Corporation Limulus lysate turbidity test for pyrogens
JPS5813516A (ja) * 1981-07-16 1983-01-26 Seikagaku Kogyo Co Ltd エンドトキシン特異性のカブトガニ・アメボサイト・ライゼート及びその製造方法
SE431228B (sv) * 1981-12-17 1984-01-23 Kenneth Soderhell Sett att bestemma bakteriella endotoxin medelst profenoloxidashaltigt blodkroppslysat fran kreftdjur eller insekter och reagens herfor
JPS5927828A (ja) * 1982-08-05 1984-02-14 Seikagaku Kogyo Co Ltd アメボサイト・ライゼートの調製方法
EP0347951B1 (en) * 1984-06-27 1993-08-04 Wako Pure Chemical Industries, Ltd. Apparatus for measuring endotoxin
JPH0715474B2 (ja) * 1988-02-27 1995-02-22 和光純薬工業株式会社 エンドトキシンの測定法
JPH0711523B2 (ja) * 1988-03-16 1995-02-08 和光純薬工業株式会社 試薬の調製方法
CA1328074C (en) * 1988-09-01 1994-03-29 Shigenori Tanaka Horseshoe crab amebocyte lysate factor g inhibitor

Also Published As

Publication number Publication date
JPH0715474B2 (ja) 1995-02-22
EP0330991A2 (en) 1989-09-06
EP0330991A3 (en) 1991-06-19
CA1339881C (en) 1998-05-26
JPH01219562A (ja) 1989-09-01
DE68919245D1 (de) 1994-12-15
ATE114051T1 (de) 1994-11-15
US5179006A (en) 1993-01-12
US5318893A (en) 1994-06-07
DE68919245T2 (de) 1995-05-18
EP0330991B1 (en) 1994-11-09

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