ATE117200T1 - Probucol enthaltendes arzneimittel mit gesteigerter bioverfügbarkeit. - Google Patents

Probucol enthaltendes arzneimittel mit gesteigerter bioverfügbarkeit.

Info

Publication number
ATE117200T1
ATE117200T1 AT92900932T AT92900932T ATE117200T1 AT E117200 T1 ATE117200 T1 AT E117200T1 AT 92900932 T AT92900932 T AT 92900932T AT 92900932 T AT92900932 T AT 92900932T AT E117200 T1 ATE117200 T1 AT E117200T1
Authority
AT
Austria
Prior art keywords
probucol
product containing
medicinal product
fatty acids
increased bioavailability
Prior art date
Application number
AT92900932T
Other languages
English (en)
Inventor
Kenneth G Bassler
Phadke S Deepak
Melissa P Neddermeyer
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of ATE117200T1 publication Critical patent/ATE117200T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT92900932T 1990-12-18 1991-11-15 Probucol enthaltendes arzneimittel mit gesteigerter bioverfügbarkeit. ATE117200T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62954090A 1990-12-18 1990-12-18

Publications (1)

Publication Number Publication Date
ATE117200T1 true ATE117200T1 (de) 1995-02-15

Family

ID=24523438

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92900932T ATE117200T1 (de) 1990-12-18 1991-11-15 Probucol enthaltendes arzneimittel mit gesteigerter bioverfügbarkeit.

Country Status (17)

Country Link
EP (1) EP0563112B1 (de)
JP (1) JP3127998B2 (de)
KR (1) KR0177845B1 (de)
AT (1) ATE117200T1 (de)
AU (1) AU647563B2 (de)
CA (1) CA2097827C (de)
DE (1) DE69106892T2 (de)
DK (1) DK0563112T3 (de)
ES (1) ES2069987T3 (de)
FI (1) FI102457B (de)
GR (1) GR3015837T3 (de)
HU (1) HU210565B (de)
IE (1) IE65578B1 (de)
IL (1) IL100390A (de)
NO (1) NO303526B1 (de)
NZ (1) NZ240961A (de)
WO (1) WO1992010996A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995031979A1 (en) * 1994-05-19 1995-11-30 R.P. Scherer International Corporation Solutions of aryl or heteroaryl substituted alkanoic acids in lipophilic solvents and soft gelatin capsules containing such solutions
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US6838091B2 (en) 1998-12-18 2005-01-04 Abbott Laboratories Formulations comprising lipid-regulating agents
JP2002532539A (ja) * 1998-12-18 2002-10-02 アボット・ラボラトリーズ 脂質調節剤を含む新規な製剤
US7014864B1 (en) 1998-12-18 2006-03-21 Abbott Laboratories Formulations comprising lipid-regulating agents
US6814977B1 (en) 1998-12-18 2004-11-09 Abbott Laboratories Formulations comprising lipid-regulating agents
EP1172104A4 (de) * 1999-02-23 2002-11-27 Chugai Pharmaceutical Co Ltd Zubereitungen aus weichen steckkapselen die dihydrobenzofuranderivate enthalten
US6719999B2 (en) 1999-03-31 2004-04-13 Abbott Laboratories Formulations comprising lipid-regulating agents
US6372251B2 (en) 1999-06-11 2002-04-16 Abbott Laboratories Formulations comprising lipid-regulating agents
WO2005037251A1 (en) * 2003-10-17 2005-04-28 Amylin Pharmaceuticals, Inc. Self-emulsifying drug delivery systems for hydrophobic therapeutic compounds
JP2021529781A (ja) 2018-06-26 2021-11-04 リボノバ インコーポレイテッドＲｉｂｏｎｏｖａ Ｉｎｃ． ミトコンドリア機能障害の治療方法
MA69876A1 (fr) 2022-07-01 2025-11-28 Acrotech Biopharma Inc. Compositions pharmaceutiques comprenant de l'isotrétinoïne ainsi que leurs procédés de préparation et leurs utilisations
CN116617179B (zh) * 2023-05-19 2024-03-29 齐鲁制药有限公司 一种普罗布考软胶囊及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862332A (en) * 1967-05-11 1975-01-21 Dow Chemical Co Method of lowering serum cholesterol
US4902513A (en) * 1987-07-31 1990-02-20 Jean Carvais Oral sustained release medicament

Also Published As

Publication number Publication date
FI932769A0 (fi) 1993-06-16
HUT64218A (en) 1993-12-28
NZ240961A (en) 1994-03-25
HU9301769D0 (en) 1993-09-28
JP3127998B2 (ja) 2001-01-29
AU9067891A (en) 1992-07-22
CA2097827A1 (en) 1992-06-19
AU647563B2 (en) 1994-03-24
NO932236D0 (no) 1993-06-17
DK0563112T3 (da) 1995-04-10
IE914401A1 (en) 1992-07-01
DE69106892T2 (de) 1995-05-18
DE69106892D1 (de) 1995-03-02
FI932769L (fi) 1993-06-16
IL100390A (en) 1996-12-05
WO1992010996A1 (en) 1992-07-09
HU210565B (en) 1995-05-29
CA2097827C (en) 2002-07-23
IE65578B1 (en) 1995-11-01
KR0177845B1 (ko) 1999-03-20
EP0563112A1 (de) 1993-10-06
JPH06503340A (ja) 1994-04-14
NO303526B1 (no) 1998-07-27
FI102457B1 (fi) 1998-12-15
FI102457B (fi) 1998-12-15
ES2069987T3 (es) 1995-05-16
EP0563112B1 (de) 1995-01-18
IL100390A0 (en) 1992-09-06
NO932236L (no) 1993-06-17
GR3015837T3 (en) 1995-07-31
KR930702965A (ko) 1993-11-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time