ATE117200T1 - Probucol enthaltendes arzneimittel mit gesteigerter bioverfügbarkeit. - Google Patents

Probucol enthaltendes arzneimittel mit gesteigerter bioverfügbarkeit.

Info

Publication number: ATE117200T1
Authority: AT; Austria
Prior art keywords: probucol; product containing; medicinal product; fatty acids; increased bioavailability
Prior art date: 1990-12-18

Application number

AT92900932T

Other languages

English (en)

Inventor

Kenneth G Bassler

Phadke S Deepak

Melissa P Neddermeyer

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-12-18

Filing date

1991-11-15

Publication date

1995-02-15

1991-11-15 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1995-02-15 Application granted granted Critical

1995-02-15 Publication of ATE117200T1 publication Critical patent/ATE117200T1/de

Links

FYPMFJGVHOHGLL-UHFFFAOYSA-N probucol Chemical compound C=1C(C(C)(C)C)=C(O)C(C(C)(C)C)=CC=1SC(C)(C)SC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 FYPMFJGVHOHGLL-UHFFFAOYSA-N 0.000 title abstract 3
229960003912 probucol Drugs 0.000 title abstract 3
229940126601 medicinal product Drugs 0.000 title 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 3
239000000194 fatty acid Substances 0.000 abstract 3
229930195729 fatty acid Natural products 0.000 abstract 3
150000004665 fatty acids Chemical class 0.000 abstract 3
229940079593 drug Drugs 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 1
-1 propylene glycol ester Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Hematology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Materials For Medical Uses (AREA)
Polyesters Or Polycarbonates (AREA)

AT92900932T 1990-12-18 1991-11-15 Probucol enthaltendes arzneimittel mit gesteigerter bioverfügbarkeit. ATE117200T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US62954090A	1990-12-18	1990-12-18

Publications (1)

Publication Number	Publication Date
ATE117200T1 true ATE117200T1 (de)	1995-02-15

Family

ID=24523438

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92900932T ATE117200T1 (de)	1990-12-18	1991-11-15	Probucol enthaltendes arzneimittel mit gesteigerter bioverfügbarkeit.

Country Status (17)

Country	Link
EP (1)	EP0563112B1 (de)
JP (1)	JP3127998B2 (de)
KR (1)	KR0177845B1 (de)
AT (1)	ATE117200T1 (de)
AU (1)	AU647563B2 (de)
CA (1)	CA2097827C (de)
DE (1)	DE69106892T2 (de)
DK (1)	DK0563112T3 (de)
ES (1)	ES2069987T3 (de)
FI (1)	FI102457B1 (de)
GR (1)	GR3015837T3 (de)
HU (1)	HU210565B (de)
IE (1)	IE65578B1 (de)
IL (1)	IL100390A (de)
NO (1)	NO303526B1 (de)
NZ (1)	NZ240961A (de)
WO (1)	WO1992010996A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2517095A (en) *	1994-05-19	1995-12-18	R.P. Scherer International Corporation	Solutions of aryl or heteroaryl substituted alkanoic acids in lipophilic solvents and soft gelatin capsules containing such solutions
US5858401A (en)	1996-01-22	1999-01-12	Sidmak Laboratories, Inc.	Pharmaceutical composition for cyclosporines
US6838091B2 (en)	1998-12-18	2005-01-04	Abbott Laboratories	Formulations comprising lipid-regulating agents
WO2000037057A2 (en) *	1998-12-18	2000-06-29	Abbott Laboratories	Novel formulations comprising lipid-regulating agents
US6814977B1 (en)	1998-12-18	2004-11-09	Abbott Laboratories	Formulations comprising lipid-regulating agents
US7014864B1 (en)	1998-12-18	2006-03-21	Abbott Laboratories	Formulations comprising lipid-regulating agents
WO2000050029A1 (en) *	1999-02-23	2000-08-31	Chugai Seiyaku Kabushiki Kaisha	Seam soft capsule preparations containing dihydrobenzofuran derivative
US6719999B2 (en)	1999-03-31	2004-04-13	Abbott Laboratories	Formulations comprising lipid-regulating agents
US6372251B2 (en)	1999-06-11	2002-04-16	Abbott Laboratories	Formulations comprising lipid-regulating agents
WO2005037251A1 (en) *	2003-10-17	2005-04-28	Amylin Pharmaceuticals, Inc.	Self-emulsifying drug delivery systems for hydrophobic therapeutic compounds
WO2020006125A1 (en)	2018-06-26	2020-01-02	Ribonova Inc.	Methods of treating mitochondrial dysfunction
WO2024006748A1 (en)	2022-07-01	2024-01-04	Acrotech Biopharma Inc.	Pharmaceutical compositions comprising isotretinoin and processes for preparation and uses thereof
CN116617179B (zh) *	2023-05-19	2024-03-29	齐鲁制药有限公司	一种普罗布考软胶囊及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3862332A (en) *	1967-05-11	1975-01-21	Dow Chemical Co	Method of lowering serum cholesterol
US4902513A (en) *	1987-07-31	1990-02-20	Jean Carvais	Oral sustained release medicament

1991
- 1991-11-15 DK DK92900932.2T patent/DK0563112T3/da active
- 1991-11-15 HU HU9301769A patent/HU210565B/hu unknown
- 1991-11-15 KR KR1019930701836A patent/KR0177845B1/ko not_active Expired - Lifetime
- 1991-11-15 CA CA002097827A patent/CA2097827C/en not_active Expired - Lifetime
- 1991-11-15 JP JP04501952A patent/JP3127998B2/ja not_active Expired - Lifetime
- 1991-11-15 AU AU90678/91A patent/AU647563B2/en not_active Expired
- 1991-11-15 ES ES92900932T patent/ES2069987T3/es not_active Expired - Lifetime
- 1991-11-15 AT AT92900932T patent/ATE117200T1/de not_active IP Right Cessation
- 1991-11-15 DE DE69106892T patent/DE69106892T2/de not_active Expired - Lifetime
- 1991-11-15 WO PCT/US1991/008565 patent/WO1992010996A1/en not_active Ceased
- 1991-11-15 EP EP92900932A patent/EP0563112B1/de not_active Expired - Lifetime
- 1991-12-12 NZ NZ240961A patent/NZ240961A/en not_active IP Right Cessation
- 1991-12-16 IL IL10039091A patent/IL100390A/en not_active IP Right Cessation
- 1991-12-17 IE IE440191A patent/IE65578B1/en not_active IP Right Cessation
1993
- 1993-06-16 FI FI932769A patent/FI102457B1/fi not_active IP Right Cessation
- 1993-06-17 NO NO932236A patent/NO303526B1/no not_active IP Right Cessation
1995
- 1995-04-17 GR GR950400967T patent/GR3015837T3/el unknown

Also Published As

Publication number	Publication date
AU9067891A (en)	1992-07-22
NO932236D0 (no)	1993-06-17
FI102457B (fi)	1998-12-15
GR3015837T3 (en)	1995-07-31
IE914401A1 (en)	1992-07-01
KR930702965A (ko)	1993-11-29
DK0563112T3 (da)	1995-04-10
NO303526B1 (no)	1998-07-27
IL100390A0 (en)	1992-09-06
NO932236L (no)	1993-06-17
JPH06503340A (ja)	1994-04-14
AU647563B2 (en)	1994-03-24
DE69106892D1 (de)	1995-03-02
WO1992010996A1 (en)	1992-07-09
FI932769L (fi)	1993-06-16
HU9301769D0 (en)	1993-09-28
HUT64218A (en)	1993-12-28
IL100390A (en)	1996-12-05
CA2097827A1 (en)	1992-06-19
NZ240961A (en)	1994-03-25
IE65578B1 (en)	1995-11-01
KR0177845B1 (ko)	1999-03-20
JP3127998B2 (ja)	2001-01-29
ES2069987T3 (es)	1995-05-16
DE69106892T2 (de)	1995-05-18
EP0563112B1 (de)	1995-01-18
FI932769A0 (fi)	1993-06-16
EP0563112A1 (de)	1993-10-06
CA2097827C (en)	2002-07-23
FI102457B1 (fi)	1998-12-15
HU210565B (en)	1995-05-29

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Legal Events

Date	Code	Title
1995-08-15	UEP	Publication of translation of european patent specification
2011-05-15	EEIH	Change in the person of patent owner
2012-02-15	EELA	Cancelled due to lapse of time