ATE117306T1 - Tris(isonitrile)kupfer(i)-addukte zur herstellung von radionuklid-komplexen. - Google Patents

Tris(isonitrile)kupfer(i)-addukte zur herstellung von radionuklid-komplexen.

Info

Publication number
ATE117306T1
ATE117306T1 AT88910377T AT88910377T ATE117306T1 AT E117306 T1 ATE117306 T1 AT E117306T1 AT 88910377 T AT88910377 T AT 88910377T AT 88910377 T AT88910377 T AT 88910377T AT E117306 T1 ATE117306 T1 AT E117306T1
Authority
AT
Austria
Prior art keywords
isonitrile
tris
copper
adducts
production
Prior art date
Application number
AT88910377T
Other languages
English (en)
Inventor
Tahir Westford Street Iqbal
John Henry Cain Jr
Jack Jacek Slosky
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22254227&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE117306(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Application granted granted Critical
Publication of ATE117306T1 publication Critical patent/ATE117306T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08—Copper compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT88910377T 1987-09-11 1988-09-06 Tris(isonitrile)kupfer(i)-addukte zur herstellung von radionuklid-komplexen. ATE117306T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/095,924 US4885100A (en) 1987-09-11 1987-09-11 Tris(isonitrile)copper(I) adducts for preparing radionuclide complexes

Publications (1)

Publication Number Publication Date
ATE117306T1 true ATE117306T1 (de) 1995-02-15

Family

ID=22254227

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88910377T ATE117306T1 (de) 1987-09-11 1988-09-06 Tris(isonitrile)kupfer(i)-addukte zur herstellung von radionuklid-komplexen.

Country Status (7)

Country Link
US (1) US4885100A (de)
EP (1) EP0395695B1 (de)
JP (1) JPH0653750B2 (de)
AT (1) ATE117306T1 (de)
DE (1) DE3852828T2 (de)
MX (1) MX9203600A (de)
WO (1) WO1989002433A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5028699A (en) * 1987-09-11 1991-07-02 E. I. Du Pont De Nemours And Company Process for preparing Tc-99m tris(isonitrile) copper complexes
AU8542591A (en) * 1990-06-18 1992-01-07 Mallinckrodt Medical, Inc. Metal-radionuclide complex comprising isonitrile ligands
US5210270A (en) * 1991-11-25 1993-05-11 Institute Of Nuclear Energy Research Method for synthesis and 99m C labelling of 2-alkoxyisobutylisonitrile
US5420321A (en) * 1993-08-03 1995-05-30 The Du Pont Merck Pharmaceutical Company Tris(isonitrile)copper(i) sulfates for preparing radionuclide complexes
US6263232B1 (en) 1998-04-07 2001-07-17 University Of South Florida Method and kit for locating hyperactive parathyroid tissue or adenomatious tissue in a patient and for removal of such tissue
WO2006085941A1 (en) * 2004-06-17 2006-08-17 Anazaohealth Corporation Copper-complex isonitrile positron emission tomography (pet) imaging agent and method
US7229603B2 (en) * 2004-06-17 2007-06-12 Anazaohealth Corporation Stablilized and lyophilized radiopharmaceutical agents
WO2014050272A1 (ja) * 2012-09-28 2014-04-03 住友精化株式会社 有機窒素化合物と銅（ｉ）フルオロオキソ酸塩からなる錯体の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3117938A (en) * 1959-12-23 1964-01-14 Du Pont Cuprous chloride-benzonitrile catalyst for preparing acetylene reaction products
US3197493A (en) * 1962-08-17 1965-07-27 Du Pont Copper isocyanide complexes and preparation thereof
US4451665A (en) * 1982-12-30 1984-05-29 E. I. Du Pont De Nemours And Company Process for dimerizing acrylates and methacrylates
CA1293729C (en) * 1985-08-05 1991-12-31 Alan Purdom Carpenter Jr Metal-isonitrile adducts for preparing radionuclide complexes
CA1305160C (en) * 1985-12-23 1992-07-14 Paul Louis Bergstein Ether isonitriles and radiolabeled complexes thereof

Also Published As

Publication number Publication date
EP0395695A1 (de) 1990-11-07
JPH0653750B2 (ja) 1994-07-20
JPH03501255A (ja) 1991-03-22
MX9203600A (es) 1992-07-01
EP0395695B1 (de) 1995-01-18
US4885100A (en) 1989-12-05
EP0395695A4 (en) 1991-04-17
DE3852828T2 (de) 1995-05-18
DE3852828D1 (de) 1995-03-02
WO1989002433A1 (en) 1989-03-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time