ATE118503T1 - 6-0-methylerythromycin-a-oximderivate. - Google Patents

6-0-methylerythromycin-a-oximderivate.

Info

Publication number: ATE118503T1
Authority: AT; Austria
Prior art keywords: group; substituted; benzyl; groups; phenyl
Prior art date: 1989-10-07

Application number

AT90310923T

Other languages

English (en)

Inventor

Yoko Misawa

Toshifumi Asaka

Masato Kashimura

Shigeo Morimoto

Yoshiaki Watanabe

Katsuo Hatayama

Original Assignee

Taisho Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-07

Filing date

1990-10-04

Publication date

1995-03-15

1990-10-04 Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd

1995-03-15 Application granted granted Critical

1995-03-15 Publication of ATE118503T1 publication Critical patent/ATE118503T1/de

Links

-1 6-0-METHYLERYTHROMYCIN-A OXIME Chemical class 0.000 title abstract 6
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 abstract 2
125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 1
241000894006 Bacteria Species 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000002178 anthracenyl group Chemical group C1(=CC=CC2=CC3=CC=CC=C3C=C12)* 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000005982 diphenylmethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
229960003276 erythromycin Drugs 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000005543 phthalimide group Chemical group 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000005493 quinolyl group Chemical group 0.000 abstract 1
XMVJITFPVVRMHC-UHFFFAOYSA-N roxarsone Chemical group OC1=CC=C([As](O)(O)=O)C=C1[N+]([O-])=O XMVJITFPVVRMHC-UHFFFAOYSA-N 0.000 abstract 1
125000005504 styryl group Chemical group 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT90310923T 1989-10-07 1990-10-04 6-0-methylerythromycin-a-oximderivate. ATE118503T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP26279789		1989-10-07

Publications (1)

Publication Number	Publication Date
ATE118503T1 true ATE118503T1 (de)	1995-03-15

Family

ID=17380743

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90310923T ATE118503T1 (de)	1989-10-07	1990-10-04	6-0-methylerythromycin-a-oximderivate.

Country Status (10)

Country	Link
US (1)	US5302705A (de)
EP (1)	EP0422843B1 (de)
JP (1)	JPH03204893A (de)
KR (1)	KR910007953A (de)
AT (1)	ATE118503T1 (de)
CA (1)	CA2027074A1 (de)
DE (1)	DE69016912T2 (de)
DK (1)	DK0422843T3 (de)
ES (1)	ES2071036T3 (de)
TW (1)	TW199098B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0260938B1 (de)	1986-09-18	1992-12-09	Taisho Pharmaceutical Co. Ltd	Erythromycin-A-Derivate und Verfahren zu ihrer Herstellung
AU3192695A (en) *	1994-08-12	1996-03-07	Taisho Pharmaceutical Co., Ltd.	Interleukin-5 production inhibitor
IT1276901B1 (it) *	1994-12-13	1997-11-03	Zambon Spa	Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
US5872229A (en)	1995-11-21	1999-02-16	Abbott Laboratories	Process for 6-O-alkylation of erythromycin derivatives
US5929219A (en)	1997-09-10	1999-07-27	Abbott Laboratories	9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
ATE275151T1 (de) *	1998-03-03	2004-09-15	Pfizer Prod Inc	3,6-ketal-makrolidantibiotika
HRP980189B1 (en) *	1998-04-06	2004-04-30	Pliva Pharm & Chem Works	Novel 15-membered lactams ketolides
CA2411293A1 (en)	1999-01-28	2000-07-28	Pfizer Products Inc.	Novel azalides and methods of making same
AR023264A1 (es) *	1999-04-08	2002-09-04	Hokuriku Pharmaceutical	Derivados de eritromicina
KR100428703B1 (ko) *	2000-02-02	2004-04-30	한국과학기술연구원	헬리코박터 파이로리의 성장 억제 효과를 지닌 신규 마크로라이드 화합물
US20090054634A1 (en) *	2007-08-09	2009-02-26	Vinod Kumar Kansal	Process for the preparation of clarithromycin

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2473525A1 (fr) *	1980-01-11	1981-07-17	Roussel Uclaf	Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4331803A (en) *	1980-06-04	1982-05-25	Taisho Pharmaceutical Co., Ltd.	Novel erythromycin compounds
JPS60214796A (ja) *	1984-04-06	1985-10-28	Taisho Pharmaceut Co Ltd	６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) *	1984-10-26	1986-05-22	Taisho Pharmaceut Co Ltd	６−０−メチルエリスロマイシンａ誘導体
GB8506380D0 (en) *	1985-03-12	1985-04-11	Beecham Group Plc	Chemical compounds
DK109886A (da) *	1985-03-12	1986-09-13	Beecham Group Plc	Erythromycinderivater
US4670549A (en) *	1985-03-18	1987-06-02	Taisho Pharmaceutical Co., Ltd.	Method for selective methylation of erythromycin a derivatives
US4833236A (en) *	1986-05-02	1989-05-23	Taisho Pharmaceutical Co., Ltd.	Erythromycin derivatives
US4740502A (en) *	1986-06-20	1988-04-26	Abbott Laboratories	Semisynthetic erythromycin antibiotics
EP0260938B1 (de) *	1986-09-18	1992-12-09	Taisho Pharmaceutical Co. Ltd	Erythromycin-A-Derivate und Verfahren zu ihrer Herstellung
AU1204288A (en) *	1987-02-24	1988-08-25	Beecham Group Plc	Erythromycins

1990
- 1990-10-01 US US07/590,805 patent/US5302705A/en not_active Expired - Fee Related
- 1990-10-02 TW TW079108273A patent/TW199098B/zh active
- 1990-10-03 JP JP2265812A patent/JPH03204893A/ja active Pending
- 1990-10-04 DE DE69016912T patent/DE69016912T2/de not_active Expired - Fee Related
- 1990-10-04 DK DK90310923.9T patent/DK0422843T3/da active
- 1990-10-04 AT AT90310923T patent/ATE118503T1/de not_active IP Right Cessation
- 1990-10-04 EP EP90310923A patent/EP0422843B1/de not_active Expired - Lifetime
- 1990-10-04 ES ES90310923T patent/ES2071036T3/es not_active Expired - Lifetime
- 1990-10-05 CA CA002027074A patent/CA2027074A1/en not_active Abandoned
- 1990-10-06 KR KR1019900015911A patent/KR910007953A/ko not_active Ceased

Also Published As

Publication number	Publication date
ES2071036T3 (es)	1995-06-16
DK0422843T3 (da)	1995-04-03
US5302705A (en)	1994-04-12
TW199098B (de)	1993-02-01
EP0422843A3 (en)	1991-09-18
KR910007953A (ko)	1991-05-30
DE69016912T2 (de)	1995-07-06
JPH03204893A (ja)	1991-09-06
DE69016912D1 (de)	1995-03-23
CA2027074A1 (en)	1991-04-08
EP0422843B1 (de)	1995-02-15
EP0422843A2 (de)	1991-04-17

Legal Events

Date	Code	Title	Description
1995-10-15	UEP	Publication of translation of european patent specification
1997-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
BR9703447A (pt)	1998-11-10	Novos compostos 3-(piperid-4-il)-1,2-benzisoxazol e 3-(piperazin-4-il) 1,2-benzisoxazol processos para a preparação dos mesmos e composições farmacêuticas contendo os mesmo
DK0418175T3 (da)	1996-08-05	Isoxazoler som herbicider
DE69016912D1 (de)	1995-03-23	6-0-Methylerythromycin-A-Oximderivate.
DK1105393T3 (da)	2004-02-09	Bicykliske piperidin- og piperazinforbindelser med 5-HT6-receptoraffinitet
FI923264A0 (fi)	1992-07-16	Nya herbicider.
DE3888756D1 (de)	1994-05-05	Carbamoylpyrrolidonderivate, ihre Verwendung und Herstellung.
NO904300D0 (no)	1990-10-03	Kinolinderivater samt fremstilling og anvendelse derav.
ATE74608T1 (de)	1992-04-15	Chinolincarbonsaeure-derivate.
ATE107632T1 (de)	1994-07-15	Pyrimidinyl herbizides mittel.
DK0404359T3 (da)	1994-07-25	Dibenzothiazepin-derivater, der er nyttige som antispasmodiske midler
ES2191341T3 (es)	2003-09-01	Derivados de la 2-fenoxianilina.
DE3581029D1 (de)	1991-02-07	Substituierte carbodiimide.
SE9001269L (sv)	1990-10-16	2-substituerade n,n'-ditrimetoxbensoylpiperaziner, en framstaellningsmetod foer dessa samt terapeutiska kompositioner som innehaaller dem
ATE191458T1 (de)	2000-04-15	Benzol-derivate
ATE226572T1 (de)	2002-11-15	Kondensierte indan-derivate und ihre salze
DK0435235T3 (da)	1995-05-22	Nye isoquinolinderivater og salte deraf
FI956016A0 (fi)	1995-12-14	1,2-silloitettujen 1,4-dihydropyridiinien käyttö lääkeaineina
ATE5724T1 (de)	1984-01-15	Guanidinverbindungen, verfahren zu deren herstellung und diese enthaltende zusammensetzungen.
TH18321A (th)	1996-04-25	สารออกฤทธิ์ต้านตัวรับแทคิไคนินชนิดนอนเพปไทด์
TH27618B (th)	1998-01-16	สารประกอบเพนทะไซคลิค
TH8571A (th)	1991-03-01	สารฆ่าอาร์โธรพอดชนิดซับสทิทิวเทดเซมิคาร์มาโซน