ATE118773T1 - Verfahren zur herstellung von 2-(3-pyridyl)- tetrahydrothiopyran-2-carbonsäurethioamid-1- (1r,2r)oxyden, die so erhaltenen 2-(3-pyridyl)- tetrahydrothiopyran-2-carbothioamid-1- (1r,2r)oxyde und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents

Verfahren zur herstellung von 2-(3-pyridyl)- tetrahydrothiopyran-2-carbonsäurethioamid-1- (1r,2r)oxyden, die so erhaltenen 2-(3-pyridyl)- tetrahydrothiopyran-2-carbothioamid-1- (1r,2r)oxyde und diese enthaltende pharmazeutische zusammenstellungen.

Info

Publication number: ATE118773T1
Authority: AT; Austria
Prior art keywords: tetrahydrothiopyran; pyridyl; oxides; carbothiopyran; pharmaceutical compositions
Prior art date: 1989-10-31

Application number

AT90403061T

Other languages

English (en)

Inventor

Jean-Claude Aloup

Claude James

Rodolphe Margraff

Original Assignee

Rhone Poulenc Sante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-31

Filing date

1990-10-30

Publication date

1995-03-15

1990-10-30 Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante

1995-03-15 Application granted granted Critical

1995-03-15 Publication of ATE118773T1 publication Critical patent/ATE118773T1/de

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
YBQVLKIMKZFEIM-BDJLRTHQSA-N (1r,2r)-1-oxo-2-pyridin-3-ylthiane-2-carbothioamide Chemical class C=1C=CN=CC=1[C@@]1(C(=S)N)CCCC[S@]1=O YBQVLKIMKZFEIM-BDJLRTHQSA-N 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 1
-1 alkyl isothiocyanate Chemical class 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT90403061T 1989-10-31 1990-10-30 Verfahren zur herstellung von 2-(3-pyridyl)- tetrahydrothiopyran-2-carbonsäurethioamid-1- (1r,2r)oxyden, die so erhaltenen 2-(3-pyridyl)- tetrahydrothiopyran-2-carbothioamid-1- (1r,2r)oxyde und diese enthaltende pharmazeutische zusammenstellungen. ATE118773T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8914273A FR2653770B1 (fr)	1989-10-31	1989-10-31	Procede de preparation de (pyridyl-3)-2 tetrahydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r), les (pyridyl-3)-2 tetrhydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r) ainsi obtenus et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number	Publication Date
ATE118773T1 true ATE118773T1 (de)	1995-03-15

Family

ID=9386963

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90403061T ATE118773T1 (de)	1989-10-31	1990-10-30	Verfahren zur herstellung von 2-(3-pyridyl)- tetrahydrothiopyran-2-carbonsäurethioamid-1- (1r,2r)oxyden, die so erhaltenen 2-(3-pyridyl)- tetrahydrothiopyran-2-carbothioamid-1- (1r,2r)oxyde und diese enthaltende pharmazeutische zusammenstellungen.

Country Status (25)

Country	Link
US (1)	US5120852A (de)
EP (1)	EP0426557B1 (de)
JP (1)	JPH03153684A (de)
KR (1)	KR910007921A (de)
AT (1)	ATE118773T1 (de)
AU (1)	AU641950B2 (de)
CA (1)	CA2028985A1 (de)
DE (1)	DE69017146T2 (de)
DK (1)	DK0426557T3 (de)
ES (1)	ES2068361T3 (de)
FI (1)	FI905358A7 (de)
FR (1)	FR2653770B1 (de)
GR (1)	GR3015159T3 (de)
HU (1)	HU212501B (de)
IE (1)	IE66252B1 (de)
IL (1)	IL96160A (de)
MA (1)	MA21989A1 (de)
NO (1)	NO177707C (de)
NZ (1)	NZ235872A (de)
OA (1)	OA09324A (de)
PL (1)	PL164269B1 (de)
PT (1)	PT95758A (de)
RU (1)	RU1838311C (de)
TN (1)	TNSN90128A1 (de)
ZA (1)	ZA908679B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9001327D0 (en) *	1990-01-19	1990-03-21	May & Baker Ltd	New compositions of matter
FR2702213B1 (fr) *	1993-03-02	1995-04-07	Rhone Poulenc Rorer Sa	Procédé de préparation de N-méthyl (pyridyl-3)-2 tétrahydrothiopyrannecarbothioamide-2-oxyde-1-(1R,2R).
GB9314133D0 (en) *	1993-07-08	1993-08-18	Rhone Poulenc Rorer Ltd	New process
GB9321939D0 (en) *	1993-10-25	1993-12-15	Rhone Poulenc Rorer Ltd	New process

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3395142A (en) *	1963-11-27	1968-07-30	Rohm & Haas	Aminoethylene compositions
IE49570B1 (en) *	1979-03-30	1985-10-30	Rhone Poulenc Ind	2-(pyrid-2-yl)tetrahydrothiophene derivatives
FR2488609A1 (fr) *	1980-08-18	1982-02-19	Rhone Poulenc Ind	Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent
AU543387B2 (en) *	1981-05-27	1985-04-18	Rhone-Poulenc Sante	Thioformamide derivatives
FR2528849B1 (fr) *	1982-06-17	1985-06-21	Rhone Poulenc Sante	Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent
DE3367631D1 (en) *	1983-06-16	1987-01-02	Rhone Poulenc Sante	Process for the electrochemical production of sulfoxides of thioformamide derivatives useful as medicines

1989
- 1989-10-31 FR FR8914273A patent/FR2653770B1/fr not_active Expired - Lifetime
1990
- 1990-10-26 MA MA22260A patent/MA21989A1/fr unknown
- 1990-10-29 NZ NZ235872A patent/NZ235872A/en unknown
- 1990-10-29 IL IL9616090A patent/IL96160A/en not_active IP Right Cessation
- 1990-10-29 PL PL90287557A patent/PL164269B1/pl unknown
- 1990-10-29 AU AU65548/90A patent/AU641950B2/en not_active Ceased
- 1990-10-29 TN TNTNSN90128A patent/TNSN90128A1/fr unknown
- 1990-10-30 ZA ZA908679A patent/ZA908679B/xx unknown
- 1990-10-30 HU HU906945A patent/HU212501B/hu not_active IP Right Cessation
- 1990-10-30 NO NO904708A patent/NO177707C/no unknown
- 1990-10-30 RU SU904831525A patent/RU1838311C/ru active
- 1990-10-30 DK DK90403061.6T patent/DK0426557T3/da active
- 1990-10-30 FI FI905358A patent/FI905358A7/fi not_active Application Discontinuation
- 1990-10-30 DE DE69017146T patent/DE69017146T2/de not_active Expired - Fee Related
- 1990-10-30 CA CA002028985A patent/CA2028985A1/fr not_active Abandoned
- 1990-10-30 EP EP90403061A patent/EP0426557B1/de not_active Expired - Lifetime
- 1990-10-30 AT AT90403061T patent/ATE118773T1/de not_active IP Right Cessation
- 1990-10-30 IE IE390290A patent/IE66252B1/en not_active IP Right Cessation
- 1990-10-30 ES ES90403061T patent/ES2068361T3/es not_active Expired - Lifetime
- 1990-10-30 KR KR1019900017459A patent/KR910007921A/ko not_active Ceased
- 1990-10-31 PT PT95758A patent/PT95758A/pt unknown
- 1990-10-31 OA OA59883A patent/OA09324A/xx unknown
- 1990-10-31 US US07/607,003 patent/US5120852A/en not_active Expired - Fee Related
- 1990-10-31 JP JP2292249A patent/JPH03153684A/ja active Pending
1995
- 1995-02-23 GR GR940402967T patent/GR3015159T3/el unknown

Also Published As

Publication number	Publication date
FR2653770B1 (fr)	1992-01-03
HUT59397A (en)	1992-05-28
AU641950B2 (en)	1993-10-07
FI905358A0 (fi)	1990-10-30
EP0426557A1 (de)	1991-05-08
AU6554890A (en)	1991-05-09
JPH03153684A (ja)	1991-07-01
IE903902A1 (en)	1991-05-08
DE69017146T2 (de)	1995-07-06
DK0426557T3 (da)	1995-03-27
MA21989A1 (fr)	1991-07-01
TNSN90128A1 (fr)	1991-03-05
NO904708D0 (no)	1990-10-30
NO177707C (no)	1995-11-08
EP0426557B1 (de)	1995-02-22
PL287557A1 (en)	1991-12-16
PL164269B1 (pl)	1994-07-29
ZA908679B (en)	1991-08-28
RU1838311C (ru)	1993-08-30
NO177707B (no)	1995-07-31
IL96160A0 (en)	1991-07-18
US5120852A (en)	1992-06-09
FR2653770A1 (fr)	1991-05-03
HU212501B (en)	1996-07-29
FI905358A7 (fi)	1991-05-01
OA09324A (fr)	1992-09-15
GR3015159T3 (en)	1995-05-31
NO904708L (no)	1991-05-02
NZ235872A (en)	1992-05-26
PT95758A (pt)	1991-09-13
IE66252B1 (en)	1995-12-27
CA2028985A1 (fr)	1991-05-01
HU906945D0 (en)	1991-05-28
IL96160A (en)	1995-12-31
KR910007921A (ko)	1991-05-30
DE69017146D1 (de)	1995-03-30
ES2068361T3 (es)	1995-04-16

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Legal Events

Date	Code	Title	Description
1995-09-15	UEP	Publication of translation of european patent specification
1997-07-15	REN	Ceased due to non-payment of the annual fee