ATE119038T1 - Verwendung von 2-substituierten thiazolidin-4- carbonsäuren zur behandlung von katarakt. - Google Patents
Verwendung von 2-substituierten thiazolidin-4- carbonsäuren zur behandlung von katarakt.Info
- Publication number
- ATE119038T1 ATE119038T1 AT89312875T AT89312875T ATE119038T1 AT E119038 T1 ATE119038 T1 AT E119038T1 AT 89312875 T AT89312875 T AT 89312875T AT 89312875 T AT89312875 T AT 89312875T AT E119038 T1 ATE119038 T1 AT E119038T1
- Authority
- AT
- Austria
- Prior art keywords
- cataract
- treatment
- carboxylic acids
- aliphatic
- carbons
- Prior art date
Links
- 208000002177 Cataract Diseases 0.000 title abstract 2
- -1 2-SUBSTITUTED THIAZOLIDINE-4-CARBOXYLIC Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- OGYGFUAIIOPWQD-UHFFFAOYSA-N 1,3-thiazolidine Chemical compound C1CSCN1 OGYGFUAIIOPWQD-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28276788A | 1988-12-09 | 1988-12-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE119038T1 true ATE119038T1 (de) | 1995-03-15 |
Family
ID=23083041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89312875T ATE119038T1 (de) | 1988-12-09 | 1989-12-11 | Verwendung von 2-substituierten thiazolidin-4- carbonsäuren zur behandlung von katarakt. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5399573A (de) |
| EP (1) | EP0373002B1 (de) |
| JP (1) | JPH02202818A (de) |
| AT (1) | ATE119038T1 (de) |
| DE (1) | DE68921436T2 (de) |
| ES (1) | ES2068253T3 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0494405T3 (da) * | 1991-01-10 | 1996-11-18 | Transcend Therapeutics Inc | Anvendelse af thiazolidin-4-carboxylatderivater til behandling af lungesygdomme |
| US5747459A (en) * | 1991-02-04 | 1998-05-05 | Nestec, Ltd. | Method for insuring adequate intracellular glutathione in tissue |
| US5430045A (en) * | 1992-04-23 | 1995-07-04 | Free Radical Sciences, Inc. | Method of reducing or preventing bone marrow hypoplasia |
| US5208249A (en) * | 1992-08-20 | 1993-05-04 | Clintec Nutrition Co. | Method for stimulating intracellular synthesis of glutathione using esters of L-2-oxothiazolidine-4-carboxylate |
| JPH09505057A (ja) * | 1993-11-19 | 1997-05-20 | ザ・ユニバーシティ・オブ・シドニー | 白内障を予防または制御するための方法 |
| US5447712A (en) * | 1993-12-09 | 1995-09-05 | Free Radical Sciences | Method of reducing cyclophosphamide induced hemorrhagic cystitis |
| US5925658A (en) * | 1995-03-02 | 1999-07-20 | Sankyo Company, Limited | Optically active thiazolidinone derivative |
| US5624955A (en) * | 1995-05-03 | 1997-04-29 | Regents Of The University Of Minnesota | Compounds that enhance the concentration of glutathione in tissues |
| US5576278A (en) * | 1995-06-07 | 1996-11-19 | Alcon Laboratories, Inc. | Stable liquid enzyme compositions and methods of use |
| US5686450A (en) * | 1995-06-07 | 1997-11-11 | Alcon Laboratories, Inc. | Use of N,N'-bis(mercaptoacetyl) hydrazine derivatives as anticataract agents |
| ES2156633T3 (es) * | 1996-03-25 | 2001-07-01 | Alcon Lab Inc | Derivados del acido tiazolidina-4-carboxilico como agentes citoprotectores. |
| HRP20241559T1 (hr) | 2016-05-18 | 2025-02-14 | Sound Pharmaceuticals Incorporated | Ebselen za uporabu u liječenju menierove bolesti |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4351826A (en) * | 1980-02-29 | 1982-09-28 | Massachusetts Institute Of Technology | Process for preventing or reversing cataract formation using acrylamides |
| US4526789A (en) * | 1980-02-29 | 1985-07-02 | Massachusetts Institute Of Technology | Process for preventing or reversing cataract formation |
| US4474817A (en) * | 1980-02-29 | 1984-10-02 | Massachusetts Institute Of Technology | Process for preventing or reversing cataract formation |
| JPS5718615A (en) * | 1980-07-07 | 1982-01-30 | Senjiyu Seiyaku Kk | Anticataract agent |
| US4335210A (en) * | 1981-02-11 | 1982-06-15 | Cornell Research Foundation | Method of producing L-cysteine |
| US4434158A (en) * | 1981-02-11 | 1984-02-28 | Cornell Research Foundation | Cysteine delivery system |
| US4438124A (en) * | 1981-02-11 | 1984-03-20 | Cornell Research Foundation, Inc. | Cysteine delivery system |
| US4647571A (en) * | 1981-02-11 | 1987-03-03 | Cornell Research Foundation | Cysteine delivery composition |
| US4665082A (en) * | 1981-02-11 | 1987-05-12 | Cornell Research Foundation | Cysteine delivery system |
| US5091421A (en) * | 1987-06-04 | 1992-02-25 | Massachusetts Institute Of Technology | Chemical prevention or reversal of cataract by phase separation inhibitors |
-
1989
- 1989-12-11 JP JP1321250A patent/JPH02202818A/ja active Pending
- 1989-12-11 EP EP89312875A patent/EP0373002B1/de not_active Expired - Lifetime
- 1989-12-11 DE DE68921436T patent/DE68921436T2/de not_active Expired - Fee Related
- 1989-12-11 AT AT89312875T patent/ATE119038T1/de not_active IP Right Cessation
- 1989-12-11 ES ES89312875T patent/ES2068253T3/es not_active Expired - Lifetime
-
1992
- 1992-09-01 US US07/938,967 patent/US5399573A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0373002A3 (de) | 1991-07-31 |
| EP0373002A2 (de) | 1990-06-13 |
| ES2068253T3 (es) | 1995-04-16 |
| US5399573A (en) | 1995-03-21 |
| EP0373002B1 (de) | 1995-03-01 |
| DE68921436T2 (de) | 1995-08-10 |
| JPH02202818A (ja) | 1990-08-10 |
| DE68921436D1 (de) | 1995-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |