ATE119391T1 - Mittel zur verzögerten freisetzung von chlorhexidin. - Google Patents

Mittel zur verzögerten freisetzung von chlorhexidin.

Info

Publication number: ATE119391T1
Authority: AT; Austria
Prior art keywords: chlorhexidine; sustained release; release agent; release; sustained
Prior art date: 1989-03-16

Application number

AT90302837T

Other languages

English (en)

Inventor

Michael Friedman

Original Assignee

Yissum Res Dev Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-16

Filing date

1990-03-16

Publication date

1995-03-15

1990-03-16 Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co

1995-03-15 Application granted granted Critical

1995-03-15 Publication of ATE119391T1 publication Critical patent/ATE119391T1/de

Links

238000013268 sustained release Methods 0.000 title abstract 3
239000012730 sustained-release form Substances 0.000 title abstract 3
GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 title abstract 2
229960003260 chlorhexidine Drugs 0.000 title abstract 2
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
201000010099 disease Diseases 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
239000007943 implant Substances 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
108010010803 Gelatin Proteins 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229920000159 gelatin Polymers 0.000 abstract 1
239000008273 gelatin Substances 0.000 abstract 1
235000019322 gelatine Nutrition 0.000 abstract 1
235000011852 gelatine desserts Nutrition 0.000 abstract 1
235000011187 glycerol Nutrition 0.000 abstract 1
RARSHUDCJQSEFJ-UHFFFAOYSA-N p-Hydroxypropiophenone Chemical compound CCC(=O)C1=CC=C(O)C=C1 RARSHUDCJQSEFJ-UHFFFAOYSA-N 0.000 abstract 1
208000028169 periodontal disease Diseases 0.000 abstract 1
239000004014 plasticizer Substances 0.000 abstract 1
230000002035 prolonged effect Effects 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0063—Periodont
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/50—Preparations specially adapted for dental root treatment
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Oral & Maxillofacial Surgery (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Materials For Medical Uses (AREA)

AT90302837T 1989-03-16 1990-03-16 Mittel zur verzögerten freisetzung von chlorhexidin. ATE119391T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/324,505 US5002769A (en)	1987-03-13	1989-03-16	Compositions for the sustained-release of chlorhexidine

Publications (1)

Publication Number	Publication Date
ATE119391T1 true ATE119391T1 (de)	1995-03-15

Family

ID=23263888

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90302837T ATE119391T1 (de)	1989-03-16	1990-03-16	Mittel zur verzögerten freisetzung von chlorhexidin.

Country Status (9)

Country	Link
US (1)	US5002769A (de)
EP (1)	EP0388220B1 (de)
JP (1)	JP2960098B2 (de)
AT (1)	ATE119391T1 (de)
AU (1)	AU621521B2 (de)
CA (1)	CA2011637C (de)
DE (1)	DE69017484T2 (de)
DK (1)	DK0388220T3 (de)
ES (1)	ES2068999T3 (de)

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US6117856A (en) *	1996-02-14	2000-09-12	Binderman; Itzhak	Topical bisphosphonates for prevention of bone resorption
US6197331B1 (en)	1997-07-24	2001-03-06	Perio Products Ltd.	Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity
DE19813686A1 (de) *	1998-03-27	1999-09-30	Roeko Gmbh & Co	Antibakteriell wirksames Mittel zur Behandlung oder zum Füllen von Wurzelkanälen und Herstellungsverfahren
US7074426B2 (en) *	2002-03-27	2006-07-11	Frank Kochinke	Methods and drug delivery systems for the treatment of orofacial diseases
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US9101536B2 (en)	2002-08-06	2015-08-11	Matrix Medical Llc	Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
US20040053201A1 (en) *	2002-09-17	2004-03-18	Dovgan Joseph S.	Antibacterial sponges for use in endodontic procedures and methods of use
US20040136926A1 (en) *	2002-11-08	2004-07-15	Periathamby Antony Raj	Intra-oral drug delivery system
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US7678767B2 (en)	2004-06-16	2010-03-16	Pneumrx, Inc.	Glue compositions for lung volume reduction
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MX2007006833A (es) *	2004-12-10	2007-10-08	Talima Therapeutics Inc	Composiciones y metodos para tratar condiciones de la unidad de una.
US20070160559A1 (en) *	2006-01-12	2007-07-12	Roszell James A	Skin disinfectant composition and methods for using
FR2896057A1 (fr) *	2006-01-12	2007-07-13	St Microelectronics Sa	Procede et dispositif de generation d'un nombre aleatoire dans un peripherique usb
EP2124867B1 (de) *	2007-02-09	2015-04-15	DENTSPLY International Inc.	Verfahren zur behandlung von zahnablagerungen und zur füllung von wurzelkanälen mithilfe von materialien auf wasserbasis
EP1961411A1 (de) *	2007-02-21	2008-08-27	FUJIFILM Manufacturing Europe B.V.	Zusammensetzung mit gesteuerter Freisetzung
EP1961414A1 (de) *	2007-02-21	2008-08-27	FUJIFILM Manufacturing Europe B.V.	Rekombinante Gelatine enthaltende Zusammensetzung mit gesteuerter Freisetzung
WO2008103043A1 (en) *	2007-02-21	2008-08-28	Fujifilm Manufacturing Europe B.V.	Rgd containing recombinant gelatin
US20080241795A1 (en) *	2007-03-26	2008-10-02	Block James C	Prevention and treatment of alveolar osteitis
US8541047B1 (en)	2008-03-24	2013-09-24	Richard J. Shaw	Polar antiseptic/antibacterial containing toothpick probes
US9468510B2 (en)	2008-03-24	2016-10-18	Richard J. Shaw	Floss device, a method of forming the floss device and a method of using the floss device
EP2324864A4 (de) *	2008-09-08	2013-12-18	Nat Inst For Materials Science	Verbundmaterial mit einer matrix von hohem molekulargewicht und einem verbundstoff von niedrigem molekulargewicht sowie verfahren zu seiner herstellung
WO2010091274A1 (en) *	2009-02-06	2010-08-12	Skinvisible Pharmaceuticals, Inc.	A cationic pharmaceutically active ingredient containing composition, and methods for manufacturing and using
WO2010135664A1 (en) *	2009-05-22	2010-11-25	The Trustees Of The University Of Pennsylvania	Methods of identifying and using general or alternative splicing inhibitors
WO2011103440A1 (en) *	2010-02-19	2011-08-25	Skinvisible Pharmaceuticals, Inc.	Skin disinfectant composition and methods for manufacturing and using
US8865198B2 (en)	2010-10-25	2014-10-21	Dexcel Pharma Technologies Ltd.	Method for treating a periodontal disease
DE102012001979A1 (de)	2012-02-02	2013-08-08	Voco Gmbh	Härtbares Gemisch umfassend Weichmacher mit einem polyalicyclischen Strukturelement zur Anwendung bei der Herstellung dentaler Werkstoffe
DE102012001978A1 (de)	2012-02-02	2013-08-08	Voco Gmbh	Dentale Kompositmaterialien enthaltend tricyclische Weichmacher
US20140227665A1 (en) *	2013-02-14	2014-08-14	Dentsply International Inc.	Resorbable and curable compositions for use in dentistry
CN105377355A (zh)	2013-03-14	2016-03-02	拇趾公司	治疗甲单元的感染、疾病或病症的方法
DK3003285T3 (en) *	2013-06-03	2022-04-04	Mcneil Ab	Fast farmaceutisk dosisform til frigivelse af mindst to aktive farmaceutiske ingredienser i mundhulen
CA2933065C (en)	2013-12-12	2021-08-24	Innovation Technologies, Inc.	Materials and methods for controlling infections
DE202014101882U1 (de)	2014-04-22	2014-05-02	Armin Armani	Orales Abgabesystem
CZ308891B6 (cs) *	2014-10-01	2021-08-11	Wald Pharmaceuticals s.r.o	Aplikační směs pro zvýšení účinnosti antiseptik a/nebo dezinficiens, aplikační prostředek obsahující aplikační směs, a použití této směsi
US10786448B2 (en)	2018-01-18	2020-09-29	Christian Arnold	Chewing gum composition comprising polyhexanide
DE102019000321A1 (de)	2019-01-14	2020-07-16	Beuth Hochschule Für Technik Berlin	Orale Polymerzusammensetzung mit verzögerter Freisetzung
DE102019000322A1 (de)	2019-01-14	2020-07-16	Beuth Hochschule Für Technik Berlin	Polymerzusammensetzung mit antiseptischen Eigenschaften und Verfahren zur Herstellung
CN110124099B (zh) *	2019-06-14	2022-01-11	四川涑爽医疗用品有限公司	一种长效抑菌的复配牙周塞治剂及其制备方法
DE102019122174A1 (de)	2019-08-19	2021-02-25	Voco Gmbh	Dentale polymerisierbare Zusammensetzung auf der Basis kondensierter Silane
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US2961374A (en) *	1950-10-14	1960-11-22	Lieb Hans	Injectable pharmaceutical preparation, and a method of making same
US3642003A (en) *	1969-08-26	1972-02-15	Sutures Inc	Sutures having long-lasting germicidal properties
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JPS59222406A (ja) *	1983-06-01	1984-12-14	Teijin Ltd	歯周疾患治療用製剤及びその製造法
US4758595A (en) *	1984-12-11	1988-07-19	Bausch & Lomb Incorporated	Disinfecting and preserving systems and methods of use
FR2591892B1 (fr) *	1985-12-23	1988-09-16	Pf Medicament	Association collagene/principe actifantiseptique et/ou anti-inflammatoire a titre de composition, son procede de preparation et son utilisation pour la fabrication d'une composition pharmaceutique
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IL78826A (en) *	1986-05-19	1991-05-12	Yissum Res Dev Co	Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom

1989
- 1989-03-16 US US07/324,505 patent/US5002769A/en not_active Expired - Lifetime
1990
- 1990-03-07 CA CA002011637A patent/CA2011637C/en not_active Expired - Fee Related
- 1990-03-08 AU AU51189/90A patent/AU621521B2/en not_active Ceased
- 1990-03-16 AT AT90302837T patent/ATE119391T1/de not_active IP Right Cessation
- 1990-03-16 DE DE69017484T patent/DE69017484T2/de not_active Expired - Fee Related
- 1990-03-16 EP EP90302837A patent/EP0388220B1/de not_active Expired - Lifetime
- 1990-03-16 ES ES90302837T patent/ES2068999T3/es not_active Expired - Lifetime
- 1990-03-16 JP JP2066712A patent/JP2960098B2/ja not_active Expired - Fee Related
- 1990-03-16 DK DK90302837.1T patent/DK0388220T3/da active

Also Published As

Publication number	Publication date
EP0388220B1 (de)	1995-03-08
CA2011637C (en)	2001-01-30
AU5118990A (en)	1990-09-20
DE69017484T2 (de)	1995-07-27
JP2960098B2 (ja)	1999-10-06
US5002769A (en)	1991-03-26
JPH03200726A (ja)	1991-09-02
EP0388220A3 (de)	1991-03-13
CA2011637A1 (en)	1990-09-16
EP0388220A2 (de)	1990-09-19
DK0388220T3 (da)	1995-03-27
ES2068999T3 (es)	1995-05-01
AU621521B2 (en)	1992-03-12
DE69017484D1 (de)	1995-04-13

Legal Events

Date	Code	Title	Description
2006-12-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69017484D1 (de)	1995-04-13	Mittel zur verzögerten Freisetzung von Chlorhexidin.
ES2044925T3 (es)	1994-01-16	Composiciones farmaceuticas de liberacion retardada.
DK0430474T3 (da)	1995-04-03	Præparater med vedvarende frigivelse til behandling af periodontal sygdom
EP0671175A3 (de)	1996-02-28	Pharmazeutische Zubereitungen mit verzögerter Freisetzung zur Behandlung periodontaler Erkrankungen.
ATE316786T1 (de)	2006-02-15	Behandlung von mukositis
DE68923819D1 (de)	1995-09-21	Verwendung von gamma-Hydroxy-Buttersäuresalzen zur Herstellung von pharmazeutischen Zusammensetzungen zur Verwendung bei der Behandlung von Alkoholismus und die hergestellten Zusammensetzungen.
BR9406363A (pt)	1996-02-27	Composiçao farmacêutica processo para a preparaçao da mesma uso da mesma e processo para o tratamento de doenças relacionadas com o ácido gástrico
ATE109000T1 (de)	1994-08-15	System zur freisetzung von medikamenten und dessen herstellungsmethode.
NO20004282D0 (no)	2000-08-25	Matriksproteinpreparater for sÕrheling
ATE133859T1 (de)	1996-02-15	Pharmazeutische zubereitungen mit verzögerter freisetzung zur behandlung periodontaler erkrankungen
ATE173930T1 (de)	1998-12-15	Pharmazeutische zusammensetzungen zur topischen anwendung die ein chelatierungsmittel, ein tocopherol und einen antimikrobiellen wirkstoff enthalten
DE69334087D1 (de)	2007-01-04	Arzneimittelzusammensetzung enthaltend TCF-II
DE68916651D1 (de)	1994-08-11	Heilmittel zur behandlung von toxoplasmose.
ATE33760T1 (de)	1988-05-15	Mittel zur oertlichen anwendung am koerper.