ATE119391T1 - Mittel zur verzögerten freisetzung von chlorhexidin. - Google Patents
Mittel zur verzögerten freisetzung von chlorhexidin.Info
- Publication number
- ATE119391T1 ATE119391T1 AT90302837T AT90302837T ATE119391T1 AT E119391 T1 ATE119391 T1 AT E119391T1 AT 90302837 T AT90302837 T AT 90302837T AT 90302837 T AT90302837 T AT 90302837T AT E119391 T1 ATE119391 T1 AT E119391T1
- Authority
- AT
- Austria
- Prior art keywords
- chlorhexidine
- sustained release
- release agent
- release
- sustained
- Prior art date
Links
- 238000013268 sustained release Methods 0.000 title abstract 3
- 239000012730 sustained-release form Substances 0.000 title abstract 3
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003260 chlorhexidine Drugs 0.000 title abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000007943 implant Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- RARSHUDCJQSEFJ-UHFFFAOYSA-N p-Hydroxypropiophenone Chemical compound CCC(=O)C1=CC=C(O)C=C1 RARSHUDCJQSEFJ-UHFFFAOYSA-N 0.000 abstract 1
- 208000028169 periodontal disease Diseases 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0063—Periodont
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/50—Preparations specially adapted for dental root treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/324,505 US5002769A (en) | 1987-03-13 | 1989-03-16 | Compositions for the sustained-release of chlorhexidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE119391T1 true ATE119391T1 (de) | 1995-03-15 |
Family
ID=23263888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90302837T ATE119391T1 (de) | 1989-03-16 | 1990-03-16 | Mittel zur verzögerten freisetzung von chlorhexidin. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5002769A (de) |
| EP (1) | EP0388220B1 (de) |
| JP (1) | JP2960098B2 (de) |
| AT (1) | ATE119391T1 (de) |
| AU (1) | AU621521B2 (de) |
| CA (1) | CA2011637C (de) |
| DE (1) | DE69017484T2 (de) |
| DK (1) | DK0388220T3 (de) |
| ES (1) | ES2068999T3 (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5438076A (en) * | 1988-05-03 | 1995-08-01 | Perio Products, Ltd. | Liquid polymer composition, and method of use |
| US5186936A (en) * | 1990-08-06 | 1993-02-16 | Board Of Trustees Of The University Of Illinois | Packing material for treatment of infections |
| IL97771A (en) * | 1991-04-04 | 1996-12-05 | Sion Narrow Weaving | Dry polymeric material having antimicrobial activity |
| US5385606A (en) * | 1992-07-06 | 1995-01-31 | Kowanko; Nicholas | Adhesive composition and method |
| GB2280850B (en) * | 1993-07-28 | 1997-07-30 | Johnson & Johnson Medical | Absorbable composite materials for use in the treatment of periodontal disease |
| US6015844A (en) * | 1993-03-22 | 2000-01-18 | Johnson & Johnson Medical, Inc. | Composite surgical material |
| US6001895A (en) * | 1993-03-22 | 1999-12-14 | Johnson & Johnson Medical, Inc. | Composite surgical material |
| GB9402877D0 (en) * | 1994-02-15 | 1994-04-06 | Torchinsky Alick | Mouthwash |
| US6117856A (en) * | 1996-02-14 | 2000-09-12 | Binderman; Itzhak | Topical bisphosphonates for prevention of bone resorption |
| DE69722190T2 (de) * | 1996-02-14 | 2004-05-27 | Itzhak Binderman | Topische bisphosphonate zur verhinderung der knochenresorption |
| US6197331B1 (en) | 1997-07-24 | 2001-03-06 | Perio Products Ltd. | Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity |
| DE19813686A1 (de) * | 1998-03-27 | 1999-09-30 | Roeko Gmbh & Co | Antibakteriell wirksames Mittel zur Behandlung oder zum Füllen von Wurzelkanälen und Herstellungsverfahren |
| US7074426B2 (en) * | 2002-03-27 | 2006-07-11 | Frank Kochinke | Methods and drug delivery systems for the treatment of orofacial diseases |
| US10098981B2 (en) | 2002-08-06 | 2018-10-16 | Baxter International Inc. | Biocompatible phase invertable proteinaceous compositions and methods for making and using the same |
| US9101536B2 (en) | 2002-08-06 | 2015-08-11 | Matrix Medical Llc | Biocompatible phase invertable proteinaceous compositions and methods for making and using the same |
| US20040053201A1 (en) * | 2002-09-17 | 2004-03-18 | Dovgan Joseph S. | Antibacterial sponges for use in endodontic procedures and methods of use |
| US20040136926A1 (en) * | 2002-11-08 | 2004-07-15 | Periathamby Antony Raj | Intra-oral drug delivery system |
| US20040185009A1 (en) * | 2003-03-19 | 2004-09-23 | Dexcel Pharma Technologies Ltd. | Composition and device for treating periodontal diseases |
| US20050036955A1 (en) * | 2003-08-13 | 2005-02-17 | Degould Michael D. | Bioresorbable tooth extraction socket dressing |
| US20070213768A1 (en) * | 2003-10-21 | 2007-09-13 | Irena Wasserman | Compositions and Devices Including Same Useful for Anastomosis |
| US7678767B2 (en) | 2004-06-16 | 2010-03-16 | Pneumrx, Inc. | Glue compositions for lung volume reduction |
| US7553810B2 (en) | 2004-06-16 | 2009-06-30 | Pneumrx, Inc. | Lung volume reduction using glue composition |
| US20060002970A1 (en) * | 2004-07-01 | 2006-01-05 | Aspenberg Per V | Method for coating a suture |
| US20060275230A1 (en) | 2004-12-10 | 2006-12-07 | Frank Kochinke | Compositions and methods for treating conditions of the nail unit |
| CN101115475A (zh) * | 2004-12-10 | 2008-01-30 | 塔利马治疗公司 | 用于治疗指甲单位病症的组合物和方法 |
| US20070160559A1 (en) * | 2006-01-12 | 2007-07-12 | Roszell James A | Skin disinfectant composition and methods for using |
| FR2896057A1 (fr) * | 2006-01-12 | 2007-07-13 | St Microelectronics Sa | Procede et dispositif de generation d'un nombre aleatoire dans un peripherique usb |
| EP2898873B1 (de) * | 2007-02-09 | 2021-04-28 | DENTSPLY SIRONA Inc. | Verfahren zur Behandlung von Zahnablagerungen und zur Füllung von Wurzelkanälen mithilfe von Materialien auf Wasserbasis |
| EP1961414A1 (de) * | 2007-02-21 | 2008-08-27 | FUJIFILM Manufacturing Europe B.V. | Rekombinante Gelatine enthaltende Zusammensetzung mit gesteuerter Freisetzung |
| EP1961411A1 (de) * | 2007-02-21 | 2008-08-27 | FUJIFILM Manufacturing Europe B.V. | Zusammensetzung mit gesteuerter Freisetzung |
| ATE551364T1 (de) * | 2007-02-21 | 2012-04-15 | Fujifilm Mfg Europe Bv | Nicht natürliche rekombinante gelatinen mit erweiterter funktionalität |
| US20080241795A1 (en) * | 2007-03-26 | 2008-10-02 | Block James C | Prevention and treatment of alveolar osteitis |
| US9468510B2 (en) | 2008-03-24 | 2016-10-18 | Richard J. Shaw | Floss device, a method of forming the floss device and a method of using the floss device |
| US8541047B1 (en) | 2008-03-24 | 2013-09-24 | Richard J. Shaw | Polar antiseptic/antibacterial containing toothpick probes |
| US20110251281A1 (en) * | 2008-09-08 | 2011-10-13 | National Institute For Materials Science | Composite Material Comprising High-Molecular-Weight Matrix and Low-Molecular-Weight Organic Compound and Process For Producing Same |
| WO2010091274A1 (en) * | 2009-02-06 | 2010-08-12 | Skinvisible Pharmaceuticals, Inc. | A cationic pharmaceutically active ingredient containing composition, and methods for manufacturing and using |
| WO2010135664A1 (en) * | 2009-05-22 | 2010-11-25 | The Trustees Of The University Of Pennsylvania | Methods of identifying and using general or alternative splicing inhibitors |
| WO2011103440A1 (en) * | 2010-02-19 | 2011-08-25 | Skinvisible Pharmaceuticals, Inc. | Skin disinfectant composition and methods for manufacturing and using |
| US8865198B2 (en) * | 2010-10-25 | 2014-10-21 | Dexcel Pharma Technologies Ltd. | Method for treating a periodontal disease |
| DE102012001978A1 (de) | 2012-02-02 | 2013-08-08 | Voco Gmbh | Dentale Kompositmaterialien enthaltend tricyclische Weichmacher |
| DE102012001979A1 (de) | 2012-02-02 | 2013-08-08 | Voco Gmbh | Härtbares Gemisch umfassend Weichmacher mit einem polyalicyclischen Strukturelement zur Anwendung bei der Herstellung dentaler Werkstoffe |
| EP2956110B1 (de) * | 2013-02-14 | 2020-08-12 | DENTSPLY SIRONA Inc. | Resorbierbare und härtbare zusammensetzungen zur verwendung in der zahnmedizin |
| CN105377355A (zh) | 2013-03-14 | 2016-03-02 | 拇趾公司 | 治疗甲单元的感染、疾病或病症的方法 |
| BR112015030140A2 (pt) * | 2013-06-03 | 2017-07-25 | Mcneil Ab | forma de dosagem farmacêutica sólida para liberação de pelo menos um ingrediente farmacêutico ativo na cavidade oral |
| MX388424B (es) | 2013-12-12 | 2025-03-19 | Innovation Tech Inc | Materiales y metodos para controlar infecciones. |
| DE202014101882U1 (de) | 2014-04-22 | 2014-05-02 | Armin Armani | Orales Abgabesystem |
| CZ308891B6 (cs) * | 2014-10-01 | 2021-08-11 | Wald Pharmaceuticals s.r.o | Aplikační směs pro zvýšení účinnosti antiseptik a/nebo dezinficiens, aplikační prostředek obsahující aplikační směs, a použití této směsi |
| US10786448B2 (en) | 2018-01-18 | 2020-09-29 | Christian Arnold | Chewing gum composition comprising polyhexanide |
| DE102019000322A1 (de) | 2019-01-14 | 2020-07-16 | Beuth Hochschule Für Technik Berlin | Polymerzusammensetzung mit antiseptischen Eigenschaften und Verfahren zur Herstellung |
| DE102019000321A1 (de) | 2019-01-14 | 2020-07-16 | Beuth Hochschule Für Technik Berlin | Orale Polymerzusammensetzung mit verzögerter Freisetzung |
| CN110124099B (zh) * | 2019-06-14 | 2022-01-11 | 四川涑爽医疗用品有限公司 | 一种长效抑菌的复配牙周塞治剂及其制备方法 |
| DE102019122174A1 (de) | 2019-08-19 | 2021-02-25 | Voco Gmbh | Dentale polymerisierbare Zusammensetzung auf der Basis kondensierter Silane |
| DE102020007979A1 (de) | 2020-12-29 | 2022-06-30 | Charité Universitätsmedizin Institut für Mikrobiologie und Infektionsimmunologie | Zusammensetzung zur Behandlung von lnfektionen mit Coronaviren |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2961374A (en) * | 1950-10-14 | 1960-11-22 | Lieb Hans | Injectable pharmaceutical preparation, and a method of making same |
| US3642003A (en) * | 1969-08-26 | 1972-02-15 | Sutures Inc | Sutures having long-lasting germicidal properties |
| US3956480A (en) * | 1974-07-01 | 1976-05-11 | Colgate-Palmolive Company | Treatment of teeth |
| US4344967A (en) * | 1979-08-07 | 1982-08-17 | Devro, Inc. | Film forming composition and uses thereof |
| US4568535A (en) * | 1982-08-06 | 1986-02-04 | Loesche Walter J | Composition for periodontal administration |
| JPS59222406A (ja) * | 1983-06-01 | 1984-12-14 | Teijin Ltd | 歯周疾患治療用製剤及びその製造法 |
| US4758595A (en) * | 1984-12-11 | 1988-07-19 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| FR2591892B1 (fr) * | 1985-12-23 | 1988-09-16 | Pf Medicament | Association collagene/principe actifantiseptique et/ou anti-inflammatoire a titre de composition, son procede de preparation et son utilisation pour la fabrication d'une composition pharmaceutique |
| JPS62223115A (ja) * | 1986-03-25 | 1987-10-01 | Rooto Seiyaku Kk | 歯周病治療剤 |
| IL78826A (en) * | 1986-05-19 | 1991-05-12 | Yissum Res Dev Co | Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom |
-
1989
- 1989-03-16 US US07/324,505 patent/US5002769A/en not_active Expired - Lifetime
-
1990
- 1990-03-07 CA CA002011637A patent/CA2011637C/en not_active Expired - Fee Related
- 1990-03-08 AU AU51189/90A patent/AU621521B2/en not_active Ceased
- 1990-03-16 AT AT90302837T patent/ATE119391T1/de not_active IP Right Cessation
- 1990-03-16 ES ES90302837T patent/ES2068999T3/es not_active Expired - Lifetime
- 1990-03-16 DE DE69017484T patent/DE69017484T2/de not_active Expired - Fee Related
- 1990-03-16 DK DK90302837.1T patent/DK0388220T3/da active
- 1990-03-16 JP JP2066712A patent/JP2960098B2/ja not_active Expired - Fee Related
- 1990-03-16 EP EP90302837A patent/EP0388220B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0388220A2 (de) | 1990-09-19 |
| JP2960098B2 (ja) | 1999-10-06 |
| DE69017484D1 (de) | 1995-04-13 |
| CA2011637C (en) | 2001-01-30 |
| DK0388220T3 (da) | 1995-03-27 |
| EP0388220A3 (de) | 1991-03-13 |
| CA2011637A1 (en) | 1990-09-16 |
| JPH03200726A (ja) | 1991-09-02 |
| EP0388220B1 (de) | 1995-03-08 |
| AU621521B2 (en) | 1992-03-12 |
| US5002769A (en) | 1991-03-26 |
| DE69017484T2 (de) | 1995-07-27 |
| ES2068999T3 (es) | 1995-05-01 |
| AU5118990A (en) | 1990-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |