ATE120795T1 - Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung. - Google Patents

Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung.

Info

Publication number
ATE120795T1
ATE120795T1 AT88906511T AT88906511T ATE120795T1 AT E120795 T1 ATE120795 T1 AT E120795T1 AT 88906511 T AT88906511 T AT 88906511T AT 88906511 T AT88906511 T AT 88906511T AT E120795 T1 ATE120795 T1 AT E120795T1
Authority
AT
Austria
Prior art keywords
phage
antimicrobial agents
cells
antimicrobial
medicinal
Prior art date
Application number
AT88906511T
Other languages
English (en)
Inventor
Jesse M Jaynes
Frederick M Enright
Kenneth L White
Original Assignee
Univ Louisiana State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Louisiana State filed Critical Univ Louisiana State
Application granted granted Critical
Publication of ATE120795T1 publication Critical patent/ATE120795T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Insects & Arthropods (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT88906511T 1987-07-06 1988-07-06 Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung. ATE120795T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6965387A 1987-07-06 1987-07-06

Publications (1)

Publication Number Publication Date
ATE120795T1 true ATE120795T1 (de) 1995-04-15

Family

ID=22090376

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88906511T ATE120795T1 (de) 1987-07-06 1988-07-06 Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung.

Country Status (8)

Country Link
US (1) US6303568B1 (de)
EP (1) EP0365598B1 (de)
KR (1) KR970005048B1 (de)
AT (1) ATE120795T1 (de)
AU (1) AU2071488A (de)
CA (1) CA1327311C (de)
DE (1) DE3853535T2 (de)
WO (1) WO1989000199A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0590301A2 (de) * 1986-07-25 1994-04-06 Louisiana State University and Agricultural and Mechanical College Verfahren zum Schutz von Pflanzen gegen Krankheit und Befall, durch Geneinbau und diese Gene enthaltende Vektoren und Pflanzenzellen
US5861478A (en) * 1987-07-06 1999-01-19 Helix Biomedix, Inc. Lytic peptides
WO1989000194A1 (en) * 1987-07-06 1989-01-12 Louisiana State University Agricultural And Mechan Inhibition of eucaryotic pathogens and neoplasms and stimulation of fibroblasts and lymphocytes with lytic peptides
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
US6156568A (en) * 1993-06-30 2000-12-05 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transformed eukaryotic cells
AU7321294A (en) * 1993-06-30 1995-01-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College, The Transformed eukaryotic cells, and transposon-based transformation vectors
AU7217194A (en) * 1993-06-30 1995-01-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College, The Transformed mammalian cells capable of expressing cecropin b
US5856178A (en) * 1993-08-30 1999-01-05 Utah State University DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same
US5998698A (en) * 1995-06-07 1999-12-07 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transgenic fish capable of expressing exogenous lytic peptides
US6288212B1 (en) 1998-08-28 2001-09-11 The University Of British Columbia Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor
EP1135535A2 (de) * 1998-12-03 2001-09-26 Phagetech Inc. Entwicklung von antimikrobiellen mittel auf der basis des bakteriophagen-genoms
US6982153B1 (en) 1998-12-03 2006-01-03 Targanta Therapeutics, Inc. DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides
US6753407B2 (en) 2000-08-15 2004-06-22 North Carolina State University Antimicrobial peptides isolated from fish
WO2002014346A2 (en) * 2000-08-15 2002-02-21 North Carolina State University Antimicrobial peptides isolated from fish
CA2433386C (en) 2000-12-19 2006-11-21 Targanta Therapeutics Inc. Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein staau_r9
US20080124787A1 (en) * 2001-02-13 2008-05-29 Avigenics, Inc. Microinjection devices and methods of use
US20050209157A1 (en) * 2001-03-28 2005-09-22 Owen Donald R Short bioactive peptides and methods for their use
US6875744B2 (en) * 2001-03-28 2005-04-05 Helix Biomedix, Inc. Short bioactive peptides
CA2441562C (en) * 2001-03-28 2013-05-14 Helix Biomedix, Inc. Short bioactive peptides and methods for their use
CA2482995C (en) * 2002-04-22 2013-01-29 Dow Global Technologies Inc. Low-cost production of peptides
US20040172667A1 (en) 2002-06-26 2004-09-02 Cooper Richard K. Administration of transposon-based vectors to reproductive organs
US20040235011A1 (en) * 2002-06-26 2004-11-25 Cooper Richard K. Production of multimeric proteins
US7527966B2 (en) 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
CA2515108A1 (en) * 2003-02-07 2004-08-26 Wisconsin Alumni Research Foundation Directed genetic modifications of human stem cells
US8071364B2 (en) 2003-12-24 2011-12-06 Transgenrx, Inc. Gene therapy using transposon-based vectors
US20050282755A1 (en) * 2004-03-18 2005-12-22 Ansata Therapeutics, Inc. Compositions having antimicrobial activity and uses thereof
AU2006212922B2 (en) * 2005-02-09 2011-04-21 Helix Biomedix Inc. Antimicrobial hexapeptides
US20070129690A1 (en) 2005-12-02 2007-06-07 Joel Rosenblatt Catheter with polymeric coating
US20080188830A1 (en) * 2007-02-06 2008-08-07 Arrow International, Inc. Selectively reinforced medical devices
US20090175967A1 (en) * 2008-01-04 2009-07-09 Nutracea Methods for treatment of intestinal carcinogenesis with rice bran
KR101863136B1 (ko) * 2008-01-24 2018-05-31 에스퍼란스 파마슈티컬스, 인코포레이티드 용해 도메인 융합 구성물 및 이를 제조하고 사용하는 방법
WO2010036978A2 (en) 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of growth hormone
WO2010036976A2 (en) 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of antibodies
US20100082097A1 (en) * 2008-10-01 2010-04-01 Joel Rosenblatt Article Containing Segregated Biguanide and Lewis Acid
US9150881B2 (en) 2009-04-09 2015-10-06 Proteovec Holding, L.L.C. Production of proteins using transposon-based vectors
IL238323B2 (en) 2012-10-30 2023-11-01 Esperance Pharmaceuticals Inc Antibody/drug conjugates and methods of use
CN110754400B (zh) * 2019-10-28 2022-04-26 长江大学 一种提高黄鳝苗种人工孵化率的方法
WO2021225663A1 (en) * 2020-04-16 2021-11-11 Old Dominion University Research Foundation Systems and methods for bacterial biofilm inactivation

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR489987A (fr) 1917-07-04 1919-03-26 Otis Pifre Ateliers Sa Perfectionnement apporté aux tours et machines similaires
GB140556A (en) 1919-04-09 1920-04-01 Sidney George Palmer Improvements in and relating to the construction of buildings
FR7869M (de) * 1967-11-03 1970-04-27
US3911110A (en) 1972-12-22 1975-10-07 Canadian Patents Dev Insecticidal compositions
US4704362A (en) 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
US4355104A (en) * 1980-06-17 1982-10-19 Kabigen Ab Bacteriolytic proteins
US4520016A (en) * 1980-06-17 1985-05-28 Kabigen Ab Bacteriolytic proteins
DE3023787A1 (de) * 1980-06-25 1982-01-21 Studiengesellschaft Kohle mbH, 4330 Mülheim Verfahren zur erhoehung der inkorporation und der expression von genetischem material in die kerne von intakten zellen mit hilfe von liposomen
JPH0795953B2 (ja) 1981-04-27 1995-10-18 ワシントン・リサ−チ・ファンデ−ション 大腸菌中のバシルス・ツリンギエンシス細晶性蛋白質
US4579821A (en) * 1981-11-23 1986-04-01 University Patents, Inc. Control of DNA sequence transcription
GB8302512D0 (en) 1983-01-29 1983-03-02 Fbc Ltd Pesticidal method
NZ209338A (en) 1983-09-14 1988-02-12 Lubrizol Genetics Inc Plasmid for the transformation of a plant cell
BR8404834A (pt) 1983-09-26 1985-08-13 Agrigenetics Res Ass Metodo para modificar geneticamente uma celula vegetal
US4751081A (en) 1984-03-26 1988-06-14 Advanced Genetic Sciences, Inc. Chitinase-producing bacteria
US4643988A (en) 1984-05-15 1987-02-17 Research Corporation Amphipathic peptides
EP0184288A1 (de) 1984-10-23 1986-06-11 Schering Agrochemicals Limited Herbizide, Insektizide und Fungizide
JPS61122299A (ja) 1984-11-19 1986-06-10 Wakunaga Seiyaku Kk 抗菌性ポリペプチド、その製造法およびその用途
US5206154A (en) * 1985-01-28 1993-04-27 Xoma Corporation Method of producing cecropins by microbiological techniques
ATE101203T1 (de) * 1985-01-28 1994-02-15 Xoma Corp Arab-promoter und verfahren zur herstellung von polypeptiden einschliesslich cecropinen mittels mikrobiologischer verfahren.
US5166321A (en) * 1985-01-28 1992-11-24 International Genetic Engineering, Inc. Cecropin polypetides with activity against Gram-positive and Gram-negative bacteria
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
EP0590301A2 (de) 1986-07-25 1994-04-06 Louisiana State University and Agricultural and Mechanical College Verfahren zum Schutz von Pflanzen gegen Krankheit und Befall, durch Geneinbau und diese Gene enthaltende Vektoren und Pflanzenzellen
US4844924A (en) 1987-09-16 1989-07-04 A. E. Staley Manufacturing Company Esterified dietary fiber products and methods
US5045531A (en) * 1989-12-18 1991-09-03 Magainin Sciences Inc. Wound treatment employing biologically active ion channel forming peptides and proteins

Also Published As

Publication number Publication date
EP0365598A1 (de) 1990-05-02
EP0365598A4 (en) 1991-04-03
EP0365598B1 (de) 1995-04-05
DE3853535T2 (de) 1995-10-12
WO1989000199A1 (en) 1989-01-12
CA1327311C (en) 1994-03-01
KR890701746A (ko) 1989-12-21
DE3853535D1 (de) 1995-05-11
KR970005048B1 (ko) 1997-04-11
AU2071488A (en) 1989-01-30
US6303568B1 (en) 2001-10-16

Similar Documents

Publication Publication Date Title
ATE120795T1 (de) Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung.
DE69013342T2 (de) Menschliche lactoferrin-cdna-sequenz.
ATE5001T1 (de) Verfahren zur herstellung eines ausgewaehlten proteins.
DE69420726D1 (de) Embryonische stammzelle zur herstellung von chimäre und transgen-ongulaten
DK0753053T3 (da) Alfavirus-cDNA-vektorer
DE3856588D1 (de) Biologisch-aktive Bakterizide/permeabilitätserhöhende Proteinbruchstücke
ATE192500T1 (de) Rekombinante viren vektoren zur expression in muskelzellen
ATE182901T1 (de) Für androgen-rezeptor-protein kodierende dna
ES8306324A1 (es) "proceso para la produccion microbiana de interferon fibroblasto humano".
DE69022290D1 (de) Lebende Impfstoffe.
BR8301918A (pt) Proteina,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,composicao,cultura de celulas,utilizacao de tal proteina,processo de expressao,processo para producao de um veiculo de expressao e processo para preparacao de uma proteina uroquinase
NL189092C (nl) Hybride menselijke leukocytinterferons, dubbelstrengs dna dat hiervoor codeert, expressievector, transformant micro-organisme, werkwijzen ter bereiding daarvan en farmaceutisch preparaat.
AR008588A1 (es) Molecula de acido nucleico aislada que hibridiza con un gen de saliva de pulga, proteina aislada codificada por dicha molecula, composicion terapeuticapara tratar la dermatitis alergica, kit de ensayo para determinar dicha dermatitis, molecula, virus y celula recombinantes, y anticuerpo aislado
ATE404668T1 (de) Wachstumsfaktor-homologe zvegf-3
DE3683267D1 (de) Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung.
FI863971A0 (fi) Farmaceutisk komposition anvaendbar vid behandling av leukopenia.
PT851926E (pt) Variantes do interferao-gama (rhu-ifn-gama) recombinante humano com estabilidade termica melhorada
ATE2442T1 (de) Verfahren zur herstellung von interferon und dabei verwendete kulturmediumzusammensetzung.
DE3778852D1 (de) Arzneimittel enthaltend das gewebeprotein pp4, verfahren zur herstellung von pp4 und zu seiner pasteurisierung sowie die verwendung von pp4.
ATE174629T1 (de) Herstellung von proteinen mittels protein 7b2
DE3852777D1 (de) Verfahren zur Konstruktion einer animalen Zellinie für die Herstellung von humanem Interferon-beta.
ATE134831T1 (de) Wirkstoffhaltige formkörper auf basis thermoplastisch verarbeitbarer elastomerer polyether-blockamide, verfahren zu ihrer herstellung und verwendung zur kontrolle von schädlingen
DE69030920D1 (de) Verfahren zur herstellung von pai-2
DE69031996D1 (de) Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung
DE3850933D1 (de) Anticoagulatorisches Protein PP4-X, seine Herstellung und Verwendung.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee