ATE121085T1 - (chinolin-2-ylmethoxy)-indole als leukotrienbiosynthese-hemmer. - Google Patents

(chinolin-2-ylmethoxy)-indole als leukotrienbiosynthese-hemmer.

Info

Publication number
ATE121085T1
ATE121085T1 AT90309149T AT90309149T ATE121085T1 AT E121085 T1 ATE121085 T1 AT E121085T1 AT 90309149 T AT90309149 T AT 90309149T AT 90309149 T AT90309149 T AT 90309149T AT E121085 T1 ATE121085 T1 AT E121085T1
Authority
AT
Austria
Prior art keywords
leukotrien
chinoline
ylmethoxy
indoles
biosynthesis inhibitors
Prior art date
Application number
AT90309149T
Other languages
English (en)
Inventor
Petpiboon Prasit
Rejean Fortin
John H Hutchinson
Michel L Belley
Serge Leger
John Gillard
Richard Frenette
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Application granted granted Critical
Publication of ATE121085T1 publication Critical patent/ATE121085T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT90309149T 1989-08-22 1990-08-21 (chinolin-2-ylmethoxy)-indole als leukotrienbiosynthese-hemmer. ATE121085T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39714489A 1989-08-22 1989-08-22
US55230090A 1990-07-18 1990-07-18

Publications (1)

Publication Number Publication Date
ATE121085T1 true ATE121085T1 (de) 1995-04-15

Family

ID=27015763

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90309149T ATE121085T1 (de) 1989-08-22 1990-08-21 (chinolin-2-ylmethoxy)-indole als leukotrienbiosynthese-hemmer.

Country Status (13)

Country Link
EP (1) EP0419049B1 (de)
JP (1) JPH0786101B2 (de)
KR (1) KR910004600A (de)
AT (1) ATE121085T1 (de)
AU (1) AU650185B2 (de)
CA (1) CA2023340C (de)
DE (1) DE69018553T2 (de)
FI (1) FI904132A7 (de)
IE (1) IE903022A1 (de)
IL (1) IL95371A (de)
NO (1) NO176606C (de)
NZ (1) NZ234883A (de)
PT (1) PT95055A (de)

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US5290798A (en) * 1991-09-30 1994-03-01 Merck Frosst Canada, Inc. (hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis
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US6339101B1 (en) 1998-08-14 2002-01-15 Gpi Nil Holdings, Inc. N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders
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Also Published As

Publication number Publication date
PT95055A (pt) 1991-04-18
CA2023340A1 (en) 1991-02-23
EP0419049B1 (de) 1995-04-12
AU650185B2 (en) 1994-06-09
FI904132A0 (fi) 1990-08-21
AU3012692A (en) 1993-02-11
AU628212B2 (en) 1992-09-10
CA2023340C (en) 2000-07-11
NZ234883A (en) 1995-01-27
IL95371A0 (en) 1991-06-30
FI904132A7 (fi) 1991-02-23
JPH03163075A (ja) 1991-07-15
JPH0786101B2 (ja) 1995-09-20
NO176606B (no) 1995-01-23
NO903678L (no) 1991-03-21
DE69018553T2 (de) 1995-10-19
EP0419049A1 (de) 1991-03-27
IE903022A1 (en) 1991-02-27
KR910004600A (ko) 1991-03-29
NO176606C (no) 1995-05-03
AU6121190A (en) 1991-02-28
DE69018553D1 (de) 1995-05-18
NO903678D0 (no) 1990-08-21
IL95371A (en) 1994-08-26

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Legal Events

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REN Ceased due to non-payment of the annual fee