ATE121134T1 - Rinder granulocyt-makrophagenkolonie stimulierender faktor. - Google Patents

Rinder granulocyt-makrophagenkolonie stimulierender faktor.

Info

Publication number
ATE121134T1
ATE121134T1 AT88904827T AT88904827T ATE121134T1 AT E121134 T1 ATE121134 T1 AT E121134T1 AT 88904827 T AT88904827 T AT 88904827T AT 88904827 T AT88904827 T AT 88904827T AT E121134 T1 ATE121134 T1 AT E121134T1
Authority
AT
Austria
Prior art keywords
stimulating factor
colony stimulating
macrophage colony
granulocyte macrophage
bovine
Prior art date
Application number
AT88904827T
Other languages
English (en)
Inventor
Paul E Baker
Douglas P Cerretti
Charles R Maliszewski
William R Clevenger
David J Cosman
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of ATE121134T1 publication Critical patent/ATE121134T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT88904827T 1987-06-25 1988-05-09 Rinder granulocyt-makrophagenkolonie stimulierender faktor. ATE121134T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6690187A 1987-06-25 1987-06-25

Publications (1)

Publication Number Publication Date
ATE121134T1 true ATE121134T1 (de) 1995-04-15

Family

ID=22072446

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88904827T ATE121134T1 (de) 1987-06-25 1988-05-09 Rinder granulocyt-makrophagenkolonie stimulierender faktor.

Country Status (7)

Country Link
EP (1) EP0383764B1 (de)
JP (1) JPH03500481A (de)
AT (1) ATE121134T1 (de)
AU (1) AU602097B2 (de)
CA (1) CA1341160C (de)
DE (1) DE3853590T2 (de)
WO (1) WO1988010310A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989010964A1 (en) * 1988-05-06 1989-11-16 Genentech, Inc. Novel bovine granulocyte-macrophage colony stimulating factor variant
EP1150666B1 (de) * 1999-02-12 2009-10-28 Washington University Gm-csf zur behandlung von morbus crohn

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ212645A (en) * 1984-07-06 1990-02-26 Sandoz Ltd Method for producing primate granulocyte-macrophage colony stimulating factor (gm-csf)
EP0238655A4 (de) * 1985-10-03 1989-09-11 Biogen Nv Menschliche granulozyt-makrophagen-kolonie mit stimulierendem faktor-ähnlichen polypeptid und deren herstellung mit hoher ausbeute in mikrobiellen zellen.
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung

Also Published As

Publication number Publication date
DE3853590D1 (de) 1995-05-18
CA1341160C (en) 2001-01-02
DE3853590T2 (de) 1996-01-04
WO1988010310A1 (en) 1988-12-29
EP0383764B1 (de) 1995-04-12
JPH03500481A (ja) 1991-02-07
EP0383764A1 (de) 1990-08-29
EP0383764A4 (en) 1990-10-24
AU1798888A (en) 1989-01-19
AU602097B2 (en) 1990-09-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time