ATE121630T1 - Voraktivierte therapeutische agentien, hergeleitet von photoaktiven verbindungen. - Google Patents

Voraktivierte therapeutische agentien, hergeleitet von photoaktiven verbindungen.

Info

Publication number
ATE121630T1
ATE121630T1 AT89911468T AT89911468T ATE121630T1 AT E121630 T1 ATE121630 T1 AT E121630T1 AT 89911468 T AT89911468 T AT 89911468T AT 89911468 T AT89911468 T AT 89911468T AT E121630 T1 ATE121630 T1 AT E121630T1
Authority
AT
Austria
Prior art keywords
preactivated
therapeutic agent
therapeutic agents
photoactive compound
photoactive compounds
Prior art date
Application number
AT89911468T
Other languages
English (en)
Inventor
Kirpal S Gulliya
Shazib Pervaiz
J Lester Matthews
Robert M Dowben
Joseph T Newman
Edward Forest
Original Assignee
Baylor Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor Res Found filed Critical Baylor Res Found
Application granted granted Critical
Publication of ATE121630T1 publication Critical patent/ATE121630T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT89911468T 1988-09-30 1989-09-26 Voraktivierte therapeutische agentien, hergeleitet von photoaktiven verbindungen. ATE121630T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/252,256 US5091385A (en) 1988-09-30 1988-09-30 Pre-activated therapeutic agents derived from photoactive compounds

Publications (1)

Publication Number Publication Date
ATE121630T1 true ATE121630T1 (de) 1995-05-15

Family

ID=22955246

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89911468T ATE121630T1 (de) 1988-09-30 1989-09-26 Voraktivierte therapeutische agentien, hergeleitet von photoaktiven verbindungen.

Country Status (8)

Country Link
US (1) US5091385A (de)
EP (1) EP0436642B1 (de)
JP (1) JP2807682B2 (de)
AT (1) ATE121630T1 (de)
AU (1) AU631142B2 (de)
CA (1) CA1329120C (de)
DE (1) DE68922399T2 (de)
WO (1) WO1990003187A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109016A (en) * 1988-05-23 1992-04-28 Georgia State University Foundation, Inc. Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions
US5177073A (en) * 1988-09-30 1993-01-05 Baylor Research Institute Therapeutic compositions derived from photoactive compounds
US5571666A (en) * 1988-10-28 1996-11-05 Oklahoma Medical Research Foundation Thiazine dyes used to inactivate HIV in biological fluids
JP2824917B2 (ja) * 1989-08-30 1998-11-18 株式会社林原生物化学研究所 抗腫瘍剤
AU653337B2 (en) * 1990-04-16 1994-09-29 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US6251644B1 (en) * 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US5516629A (en) * 1990-04-16 1996-05-14 Cryopharm Corporation Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
CA2047969A1 (en) * 1990-08-17 1992-02-18 Thomas D. Madden Benzoporphyrin vesicles
EP0544895B1 (de) * 1991-06-21 1997-08-27 Baxter International Inc. Verfahren zur inaktivierung von pathogenen in einer körperflüssigkeit
US5523077A (en) * 1992-02-06 1996-06-04 Yale University Composition and method for whitening skin
US5235045A (en) * 1992-03-19 1993-08-10 Microbiomed Corporation Non-azo naphthalimide dyes
FI950730L (fi) * 1992-08-17 1995-04-10 Quadra Logic Tech Inc Menetelmä ei-toivottujen solujen tai kudosten kasvun tuhoamiseksi tai ehkäisemiseksi
FR2696756B1 (fr) * 1992-10-14 1994-12-30 American Cyanamid Co Utilisation de composés photosensibilisateurs de type chlorine dérivés de prophyrines vinyliques pour inactiver des virus.
US5766600A (en) * 1993-08-09 1998-06-16 Microbiomed Corporation Non-azo naphtalimide dyes and uses for same
AU691672B2 (en) * 1994-09-22 1998-05-21 Baxter International Inc. Photodynamic inactivation of viral and bacterial blood contaminants with halogenated coumarin and furocoumarin sensitizers
US6310073B1 (en) * 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
ATE335513T1 (de) 1998-10-16 2006-09-15 Gen Hospital Corp Photosensitizer-konjugate zur zielrichtung von intrazellulare pathogene
AUPP751298A0 (en) * 1998-12-04 1999-01-07 Csl Limited Inactivation of non-enveloped viruses
EP2335634A1 (de) * 2000-02-11 2011-06-22 The General Hospital Corporation Photochemische Gewebeverbindung
US7073510B2 (en) * 2000-02-11 2006-07-11 The General Hospital Corporation Photochemical tissue bonding
US8215314B2 (en) * 2000-02-11 2012-07-10 The General Hospital Corporation Photochemical tissue bonding
US6800615B2 (en) 2002-04-15 2004-10-05 Board Of Trustees Of Michigan State University Antihelminthic anthraquinones and method of use thereof
WO2004043357A2 (en) 2002-11-06 2004-05-27 Medical College Of Wisconsin Research Foundation Method of making, and the use of cytotoxic agents containing elemental selenium
CN101084204B (zh) * 2004-09-23 2012-12-05 卫思道制药有限公司 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法
SI2322517T1 (sl) * 2004-09-23 2019-06-28 Wista Laboratories Ltd. Postopki za kemijsko sintezo in čiščenje diaminofenotiazinijevih spojin, vključno metiltioninijevega klorida (MTC)
US9358292B2 (en) 2007-04-08 2016-06-07 Immunolight, Llc Methods and systems for treating cell proliferation disorders
CA2906990A1 (en) * 2008-04-04 2009-10-08 Duke University Non-invasive systems and methods for in-situ photobiomodulation
WO2009149720A1 (en) * 2008-06-12 2009-12-17 Innovative Research And Development Co. (Inrad) Field application for malaria vector control using sunlight active formulated extract

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649151A (en) * 1982-09-27 1987-03-10 Health Research, Inc. Drugs comprising porphyrins

Also Published As

Publication number Publication date
AU4345089A (en) 1990-04-18
CA1329120C (en) 1994-05-03
AU631142B2 (en) 1992-11-19
EP0436642B1 (de) 1995-04-26
US5091385A (en) 1992-02-25
WO1990003187A1 (en) 1990-04-05
DE68922399T2 (de) 1995-10-05
JPH04501717A (ja) 1992-03-26
JP2807682B2 (ja) 1998-10-08
EP0436642A1 (de) 1991-07-17
DE68922399D1 (de) 1995-06-01

Similar Documents

Publication Publication Date Title
ATE121630T1 (de) Voraktivierte therapeutische agentien, hergeleitet von photoaktiven verbindungen.
RU94041950A (ru) Использование соединений ряда 3-аролоксипропиламинов в лечении недержания
DE3856594D1 (de) Mittel zur behandlung der alzheimer-krankheit
EP0815204A4 (de) Methode zur tumorbehandlung
EA200300544A1 (ru) Эффективные противоопухолевые лекарственные средства
DE3789082D1 (de) Expression eines tumorspezifischen Antigens eines rekombinanten Virusvektors sowie dessen Anwendung zur versorgenden oder heilenden Behandlung des entsprechenden Tumors.
ATE116550T1 (de) Behandlung von neoplastischen krankenheiten mit interleukin-10.
DE69116380D1 (de) Pharmazeutische zubereitung zur behandlung verlängerter gerinnungszeit
SE7902742L (sv) Disubstituerade 3-cefem-4-karboxylsyraderivat samt forfarande for framstellning derav
DE69004189D1 (de) Anordnungen zur behandlung menschlichen oder tierischen abfalls mittels mikrowellen.
HU891056D0 (en) Process for treating the diseases of the gullet and the stomach-intestine system
ATE75144T1 (de) Verwendung einer waessrigen chloritmatrix-loesung zur herstellung von arzneimitteln zur intravenoesen behandlung von tumoren.
GB1274409A (en) Process for the production of human or animal tissue products for the surgical treatment of human beings or animals
HUT36783A (en) Process for preparing 1,7-diphenyl-3-methyl-aza-7-cyano-8-methyl-nonane
NO910033D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive 2-hydroksy-3-fenoksypropylaminoforbindelser.
GR880100589A (en) Metalloporfyrines for the inversion of the toxic activity for the tumors treatment
SE8303729L (sv) Terapeutiskt medel for behandling av allergiska sjukdomstillstand, immunkomplexsjukdomar och tumorer
RU94011820A (ru) Способ лечения рака молочной железы
DE3865283D1 (de) Butylhydroxyanisole zur behandlung von retrovirus-krankheiten.
DE3467161D1 (de) Unsaturated arylalkyl ammonium salts
DK80485D0 (da) Trilostan til brug som laegemiddel
RU93000003A (ru) Способ лечения подкожной фибросаркомы
ATE127118T1 (de) 2-alkyl-3-benzoylbenzofurane zur behandlung von herzarrhythmia.
IT8806406A0 (it) Cura chimica del cancro del castagno mediante iniezione o per via corticale
DE3772047D1 (de) Pyrazin zur behandlung von haemodynamischen und metabolischen krankheiten.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee