ATE121630T1 - Voraktivierte therapeutische agentien, hergeleitet von photoaktiven verbindungen. - Google Patents

Voraktivierte therapeutische agentien, hergeleitet von photoaktiven verbindungen.

Info

Publication number
ATE121630T1
ATE121630T1 AT89911468T AT89911468T ATE121630T1 AT E121630 T1 ATE121630 T1 AT E121630T1 AT 89911468 T AT89911468 T AT 89911468T AT 89911468 T AT89911468 T AT 89911468T AT E121630 T1 ATE121630 T1 AT E121630T1
Authority
AT
Austria
Prior art keywords
preactivated
therapeutic agent
therapeutic agents
photoactive compound
photoactive compounds
Prior art date
Application number
AT89911468T
Other languages
English (en)
Inventor
Kirpal S Gulliya
Shazib Pervaiz
J Lester Matthews
Robert M Dowben
Joseph T Newman
Edward Forest
Original Assignee
Baylor Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor Res Found filed Critical Baylor Res Found
Application granted granted Critical
Publication of ATE121630T1 publication Critical patent/ATE121630T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT89911468T 1988-09-30 1989-09-26 Voraktivierte therapeutische agentien, hergeleitet von photoaktiven verbindungen. ATE121630T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/252,256 US5091385A (en) 1988-09-30 1988-09-30 Pre-activated therapeutic agents derived from photoactive compounds

Publications (1)

Publication Number Publication Date
ATE121630T1 true ATE121630T1 (de) 1995-05-15

Family

ID=22955246

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89911468T ATE121630T1 (de) 1988-09-30 1989-09-26 Voraktivierte therapeutische agentien, hergeleitet von photoaktiven verbindungen.

Country Status (8)

Country Link
US (1) US5091385A (de)
EP (1) EP0436642B1 (de)
JP (1) JP2807682B2 (de)
AT (1) ATE121630T1 (de)
AU (1) AU631142B2 (de)
CA (1) CA1329120C (de)
DE (1) DE68922399T2 (de)
WO (1) WO1990003187A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109016A (en) * 1988-05-23 1992-04-28 Georgia State University Foundation, Inc. Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions
US5177073A (en) * 1988-09-30 1993-01-05 Baylor Research Institute Therapeutic compositions derived from photoactive compounds
US5571666A (en) * 1988-10-28 1996-11-05 Oklahoma Medical Research Foundation Thiazine dyes used to inactivate HIV in biological fluids
JP2824917B2 (ja) * 1989-08-30 1998-11-18 株式会社林原生物化学研究所 抗腫瘍剤
US6251644B1 (en) * 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
EP0483304B1 (de) * 1990-04-16 2003-02-19 Baxter International Inc. Methode zur unschädlichmachung viraler und bakterieller blutverunreinigungen
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US5516629A (en) * 1990-04-16 1996-05-14 Cryopharm Corporation Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
CA2047969A1 (en) * 1990-08-17 1992-02-18 Thomas D. Madden Benzoporphyrin vesicles
EP0544895B1 (de) * 1991-06-21 1997-08-27 Baxter International Inc. Verfahren zur inaktivierung von pathogenen in einer körperflüssigkeit
US5523077A (en) * 1992-02-06 1996-06-04 Yale University Composition and method for whitening skin
US5235045A (en) * 1992-03-19 1993-08-10 Microbiomed Corporation Non-azo naphthalimide dyes
AU4695493A (en) * 1992-08-17 1994-03-15 Quadra Logic Technologies Inc. Method for destroying or inhibiting growth of unwanted cells or tissues
FR2696756B1 (fr) * 1992-10-14 1994-12-30 American Cyanamid Co Utilisation de composés photosensibilisateurs de type chlorine dérivés de prophyrines vinyliques pour inactiver des virus.
US5766600A (en) * 1993-08-09 1998-06-16 Microbiomed Corporation Non-azo naphtalimide dyes and uses for same
AU691672B2 (en) * 1994-09-22 1998-05-21 Baxter International Inc. Photodynamic inactivation of viral and bacterial blood contaminants with halogenated coumarin and furocoumarin sensitizers
US6310073B1 (en) * 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
JP2002527494A (ja) * 1998-10-16 2002-08-27 ザ・ジェネラル・ホスピタル・コーポレイション 細胞内病原体を標的付ける光増感剤である複合体
AUPP751298A0 (en) * 1998-12-04 1999-01-07 Csl Limited Inactivation of non-enveloped viruses
EP1272119B1 (de) * 2000-02-11 2010-11-24 The General Hospital Corporation Photochemische gewebeverbindung
US8215314B2 (en) * 2000-02-11 2012-07-10 The General Hospital Corporation Photochemical tissue bonding
US7073510B2 (en) * 2000-02-11 2006-07-11 The General Hospital Corporation Photochemical tissue bonding
US6800615B2 (en) 2002-04-15 2004-10-05 Board Of Trustees Of Michigan State University Antihelminthic anthraquinones and method of use thereof
JP2006505615A (ja) 2002-11-06 2006-02-16 メディカル カレッジ オブ ウィスコンシン リサーチ フォンデーション 元素セレンを含有する細胞毒性剤の作製方法および使用
US7790881B2 (en) * 2004-09-23 2010-09-07 Wista Laboratories Ltd. Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC)
EP1799662B1 (de) * 2004-09-23 2013-04-17 Wista Laboratories Ltd. Verfahren zur chemischen synthese und aufreinigung von diaminophenothiaziniumverbindungen einschliesslich methylthioniniumchlorid (mtc)
US9358292B2 (en) * 2007-04-08 2016-06-07 Immunolight, Llc Methods and systems for treating cell proliferation disorders
CN102056625B (zh) * 2008-04-04 2015-11-25 免疫之光有限责任公司 用于原位光生物调节的非侵入性系统和方法
WO2009149720A1 (en) * 2008-06-12 2009-12-17 Innovative Research And Development Co. (Inrad) Field application for malaria vector control using sunlight active formulated extract

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649151A (en) * 1982-09-27 1987-03-10 Health Research, Inc. Drugs comprising porphyrins

Also Published As

Publication number Publication date
JP2807682B2 (ja) 1998-10-08
AU631142B2 (en) 1992-11-19
WO1990003187A1 (en) 1990-04-05
JPH04501717A (ja) 1992-03-26
EP0436642B1 (de) 1995-04-26
DE68922399T2 (de) 1995-10-05
AU4345089A (en) 1990-04-18
US5091385A (en) 1992-02-25
CA1329120C (en) 1994-05-03
DE68922399D1 (de) 1995-06-01
EP0436642A1 (de) 1991-07-17

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee