ATE121791T1 - Fluorogene tryptophanase-substrate. - Google Patents
Fluorogene tryptophanase-substrate.Info
- Publication number
- ATE121791T1 ATE121791T1 AT91111918T AT91111918T ATE121791T1 AT E121791 T1 ATE121791 T1 AT E121791T1 AT 91111918 T AT91111918 T AT 91111918T AT 91111918 T AT91111918 T AT 91111918T AT E121791 T1 ATE121791 T1 AT E121791T1
- Authority
- AT
- Austria
- Prior art keywords
- tryptophanase
- substrates
- fluorogene
- amino acid
- linked
- Prior art date
Links
- 102100040653 Tryptophan 2,3-dioxygenase Human genes 0.000 title abstract 2
- 101710136122 Tryptophan 2,3-dioxygenase Proteins 0.000 title abstract 2
- 239000000758 substrate Substances 0.000 title abstract 2
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 239000007850 fluorescent dye Substances 0.000 abstract 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- GNVMUORYQLCPJZ-UHFFFAOYSA-N carbamothioic s-acid Chemical group NC(S)=O GNVMUORYQLCPJZ-UHFFFAOYSA-N 0.000 abstract 1
- GLNDAGDHSLMOKX-UHFFFAOYSA-N coumarin 120 Chemical compound C1=C(N)C=CC2=C1OC(=O)C=C2C GLNDAGDHSLMOKX-UHFFFAOYSA-N 0.000 abstract 1
- 235000018417 cysteine Nutrition 0.000 abstract 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical group O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- UPSFMJHZUCSEHU-JYGUBCOQSA-N n-[(2s,3r,4r,5s,6r)-2-[(2r,3s,4r,5r,6s)-5-acetamido-4-hydroxy-2-(hydroxymethyl)-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide Chemical compound CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@H](O)[C@@H](NC(C)=O)[C@H](OC=2C=C3OC(=O)C=C(C)C3=CC=2)O[C@@H]1CO UPSFMJHZUCSEHU-JYGUBCOQSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/20—Coumarin derivatives
- C12Q2337/22—7-Amino-4-methylcoumarin, i.e. AMC, MCA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Ceramic Products (AREA)
- Lock And Its Accessories (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/554,506 US5055594A (en) | 1990-07-19 | 1990-07-19 | Fluorogenic trypotophanase substrates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE121791T1 true ATE121791T1 (de) | 1995-05-15 |
Family
ID=24213622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91111918T ATE121791T1 (de) | 1990-07-19 | 1991-07-17 | Fluorogene tryptophanase-substrate. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5055594A (de) |
| EP (1) | EP0467318B1 (de) |
| JP (1) | JPH0671438B2 (de) |
| AT (1) | ATE121791T1 (de) |
| AU (1) | AU631102B2 (de) |
| CA (1) | CA2043124C (de) |
| DE (1) | DE69109197T2 (de) |
| FI (1) | FI97152C (de) |
| IE (1) | IE67645B1 (de) |
| MY (1) | MY107196A (de) |
| NO (1) | NO302243B1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2036770C (en) * | 1990-02-26 | 2003-09-09 | Jeffrey P. Whitten | Inhibitors of nitric oxide biosynthesis |
| ES2106040T3 (es) * | 1990-05-16 | 1997-11-01 | Abbott Lab | Ensayo para barbituratos, trazadores, inmunogenos, anticuerpos y kit. |
| FR2677023B1 (fr) * | 1991-05-30 | 1994-02-25 | Eurobio Laboratoires | Derives de coumarine hydrosolubles, leur preparation et leur utilisation comme substrat d'enzyme. |
| GB9609024D0 (en) * | 1996-05-01 | 1996-07-03 | Idg Uk Ltd | Compounds |
| US5888760A (en) * | 1997-04-10 | 1999-03-30 | Dade Microscan Inc. | Universal test systems and methods of use thereof for identifying multiple families of microorganisms |
| FR2785620B1 (fr) * | 1998-11-05 | 2003-02-07 | Bio Merieux | Detection de tous micro-organismes dans un echantillon |
| WO2000067037A2 (en) * | 1999-04-29 | 2000-11-09 | Dade Microscan Inc. | A combined rapid anti-microbial susceptibility assay and microorganism identification system |
| CN108570032B (zh) * | 2017-03-09 | 2021-04-02 | 华东理工大学 | 新型罗丹明染料及其在抗致病菌中的应用 |
| CN108727326B (zh) * | 2018-07-06 | 2021-12-21 | 南宁师范大学 | 识别半胱氨酸和谷胱甘肽的荧光探针及制备方法与应用 |
| WO2023219152A1 (ja) * | 2022-05-13 | 2023-11-16 | 中外製薬株式会社 | リチウム塩の析出工程を含む、アミノ酸の塩若しくはペプチド化合物の塩又はこれらの溶媒和物の製造方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1229212B (de) * | 1961-03-07 | 1966-11-24 | Bayer Ag | Verfahren zur Herstellung von Farbstoffen |
| US3880934A (en) * | 1972-02-10 | 1975-04-29 | Syntex Inc | Nitrophenyloxy-butanediols |
| JPS6026793B2 (ja) * | 1977-01-05 | 1985-06-25 | 味の素株式会社 | ７−ロイシルアミノ−４−メチルクマリン及びその製造方法 |
| JPS53108974A (en) * | 1977-03-03 | 1978-09-22 | Ajinomoto Co Inc | 7-arginylamino-4-methylcoumarin |
| US4215047A (en) * | 1977-06-06 | 1980-07-29 | Ajinomoto Company Incorporated | 7-(Arginylamino)-4-methylcoumarins |
| US4318980A (en) * | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| JPS5524147A (en) * | 1978-08-10 | 1980-02-21 | Ajinomoto Co Inc | Peptide derivative |
| JPH0321160B2 (de) * | 1979-05-02 | 1991-03-22 | Nat Res Dev | |
| US4259233A (en) * | 1979-10-23 | 1981-03-31 | Miles Laboratories, Inc. | β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates |
| US4476229A (en) * | 1982-11-08 | 1984-10-09 | Abbott Laboratories | Substituted carboxyfluoresceins |
| US4476228A (en) * | 1982-11-08 | 1984-10-09 | Abbott Laboratories | Determination of unsaturated thyroxine binding protein sites using fluorescence polarization techniques |
| US4557862A (en) * | 1983-10-28 | 1985-12-10 | University Patents, Inc. | Rhodamine derivatives as fluorogenic substrates for proteinases |
| DE3614647A1 (de) * | 1986-04-30 | 1987-11-05 | Euratom | 7-phenylessigsaeure-4-alkyl-coumarinylamide, verfahren zu ihrer herstellung sowie ihre verwendung in verfahren zur fluorometrischen bestimmung der aktivitaet von hydrolasen, insbesondere von penicillin-g-acylase |
-
1990
- 1990-07-19 US US07/554,506 patent/US5055594A/en not_active Expired - Fee Related
-
1991
- 1991-05-22 IE IE175991A patent/IE67645B1/en unknown
- 1991-05-27 CA CA002043124A patent/CA2043124C/en not_active Expired - Fee Related
- 1991-05-27 MY MYPI91000921A patent/MY107196A/en unknown
- 1991-05-29 AU AU78026/91A patent/AU631102B2/en not_active Ceased
- 1991-06-20 NO NO912413A patent/NO302243B1/no unknown
- 1991-07-17 EP EP91111918A patent/EP0467318B1/de not_active Expired - Lifetime
- 1991-07-17 AT AT91111918T patent/ATE121791T1/de not_active IP Right Cessation
- 1991-07-17 DE DE69109197T patent/DE69109197T2/de not_active Expired - Fee Related
- 1991-07-18 JP JP3178285A patent/JPH0671438B2/ja not_active Expired - Lifetime
- 1991-07-18 FI FI913460A patent/FI97152C/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| NO912413L (no) | 1992-01-20 |
| US5055594A (en) | 1991-10-08 |
| DE69109197T2 (de) | 1995-09-28 |
| FI913460A0 (fi) | 1991-07-18 |
| FI913460L (fi) | 1992-01-20 |
| CA2043124A1 (en) | 1992-01-20 |
| JPH0671438B2 (ja) | 1994-09-14 |
| AU7802691A (en) | 1992-01-23 |
| EP0467318B1 (de) | 1995-04-26 |
| IE67645B1 (en) | 1996-04-17 |
| EP0467318A1 (de) | 1992-01-22 |
| NO302243B1 (no) | 1998-02-09 |
| JPH04229199A (ja) | 1992-08-18 |
| FI97152B (fi) | 1996-07-15 |
| CA2043124C (en) | 1995-12-12 |
| FI97152C (fi) | 1996-10-25 |
| MY107196A (en) | 1995-09-30 |
| DE69109197D1 (de) | 1995-06-01 |
| AU631102B2 (en) | 1992-11-12 |
| IE911759A1 (en) | 1992-01-29 |
| NO912413D0 (no) | 1991-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |