ATE123306T1 - Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen. - Google Patents

Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.

Info

Publication number
ATE123306T1
ATE123306T1 AT90303484T AT90303484T ATE123306T1 AT E123306 T1 ATE123306 T1 AT E123306T1 AT 90303484 T AT90303484 T AT 90303484T AT 90303484 T AT90303484 T AT 90303484T AT E123306 T1 ATE123306 T1 AT E123306T1
Authority
AT
Austria
Prior art keywords
ascorbic acid
alpha
glycosyl
preparation
saccharide
Prior art date
Application number
AT90303484T
Other languages
English (en)
Inventor
Itaru Yamamoto
Norio Muto
Toshio Miyake
Original Assignee
Hayashibara Biochem Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1274518A external-priority patent/JP2926412B2/ja
Application filed by Hayashibara Biochem Lab filed Critical Hayashibara Biochem Lab
Application granted granted Critical
Publication of ATE123306T1 publication Critical patent/ATE123306T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/82—Acid flavourants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/16—Preparation of compounds containing saccharide radicals produced by the action of an alpha-1, 6-glucosidase, e.g. amylose, debranched amylopectin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/58—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound through only acyclic carbon atoms to a non-saccharide heterocyclic ring, e.g. bleomycin, phleomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Saccharide Compounds (AREA)
AT90303484T 1989-05-19 1990-03-30 Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen. ATE123306T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12707289 1989-05-19
JP1274518A JP2926412B2 (ja) 1989-05-19 1989-10-20 α―グリコシル―Ｌ―アスコルビン酸とその製造方法並びに用途

Publications (1)

Publication Number Publication Date
ATE123306T1 true ATE123306T1 (de) 1995-06-15

Family

ID=26463107

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90303484T ATE123306T1 (de) 1989-05-19 1990-03-30 Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.

Country Status (7)

Country Link
US (3) US5137723A (de)
EP (1) EP0398484B1 (de)
AT (1) ATE123306T1 (de)
DE (1) DE69019779T2 (de)
DK (1) DK0398484T3 (de)
ES (1) ES2075148T3 (de)
HK (1) HK111196A (de)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE123306T1 (de) * 1989-05-19 1995-06-15 Hayashibara Biochem Lab Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.
JP2832848B2 (ja) * 1989-10-21 1998-12-09 株式会社林原生物化学研究所 結晶２―Ｏ―α―Ｄ―グルコピラノシル―Ｌ―アスコルビン酸とその製造方法並びに用途
JP2926432B2 (ja) * 1990-06-11 1999-07-28 株式会社林原生物化学研究所 養毛剤
TW197375B (de) * 1990-11-19 1993-01-01 Hayashibara Biochem Lab
US5215767A (en) * 1991-03-16 1993-06-01 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Additive for aquaculture feed for fish and shellfish and aquaculture feed for fish and shellfish which contains same
JP3072535B2 (ja) * 1991-10-21 2000-07-31 株式会社林原生物化学研究所 ５−Ｏ−α−Ｄ−グルコピラノシル−Ｌ−アスコルビン酸とその製造方法並びに用途
US5272136A (en) * 1991-10-12 1993-12-21 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo 5-0-α-D-Glucopyranosyl-L-ascorbic acid, and its preparation and uses
JP3134235B2 (ja) * 1991-10-23 2001-02-13 株式会社林原生物化学研究所 ２−Ｏ−α−Ｄ−グルコピラノシル−Ｌ−アスコルビン酸高含有物の製造方法
US5314678A (en) * 1992-01-28 1994-05-24 Mallinckrodt Medical, Inc. Sodium iodide 131 I capsules
JP3134236B2 (ja) * 1992-01-30 2001-02-13 株式会社林原生物化学研究所 α−グリコシル−Ｌ−アスコルビン酸高含有物の製造方法とその製造のための分離システム
DE69310968T2 (de) * 1992-03-17 1997-09-04 Ueno Seiyaku Oyo Kenkyujo Kk Verfahren zur Herstellung von pulverförmigem kristallinem Maltitol
EP0649648B1 (de) * 1993-10-26 2001-09-19 Shiseido Company Limited Hautbleichende Mittel enthaltend Glykoside
US5455035A (en) * 1994-01-13 1995-10-03 Elizabeth Arden Company, Division Of Conopco, Inc. Clear two-phase cosmetic composition
US5935584A (en) * 1994-01-13 1999-08-10 Elizabeth Arden Company Vitamin C delivery system
GB9403855D0 (en) * 1994-03-01 1994-04-20 Scotia Holdings Plc Fatty acid derivatives
US6224376B1 (en) 1994-06-10 2001-05-01 Richard A. Cloonan Dental cleaning liquid and gel
US5837222A (en) * 1994-06-10 1998-11-17 Cloonan; Richard A. Liquid dental cleaning solution
US5573398A (en) * 1994-06-10 1996-11-12 Towle; Lawrence E. Dental hygiene device and cleaning solution
FR2733148B1 (fr) * 1995-04-20 1997-05-30 Oreal Composition pour lutter contre les taches et/ou le vieillissement de la peau, ses utilisations
US5853741A (en) * 1996-06-28 1998-12-29 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Vitamin C delivery system
RU2146921C1 (ru) * 1997-11-05 2000-03-27 Рязанский областной клинический кожно-венерологический диспансер Мазевая композиция, стимулирующая регенерацию эпителия
JP4981198B2 (ja) 1998-03-31 2012-07-18 格 山本 グリコシル−ｌ−アスコルビン酸のアシル化誘導体
AU2001253137A1 (en) 2000-04-04 2001-10-15 Amarillo Biosciences, Inc. Composition and method for promoting oral health
FR2807320B1 (fr) * 2000-04-10 2002-05-24 Oreal Utilisation de derives d'acide ascorbique pour augmenter la synthese des creramides epidermiques
FR2807322B1 (fr) 2000-04-10 2004-02-20 Oreal Composition, notamment cosmetique, comprenant de l'acide ascorbique en association avec un derive d'acide ascorbique
JP2002326924A (ja) * 2001-05-07 2002-11-15 Hayashibara Biochem Lab Inc 洗顔料
KR100440191B1 (ko) * 2001-08-23 2004-07-12 박관화 항산화 효과 및 높은 안정성을 갖는 아스코르브산 유도체및 그것의 제조방법
KR100440190B1 (ko) * 2001-08-23 2004-07-12 박관화 아카비오신-글루코실 아스코르베이트 및 그의 제조방법
FR2834641B1 (fr) * 2002-01-14 2005-04-22 Ct Regional De Lutte Contre Le Protection de la neurotoxicite de l'oxaliplatine par administration de calcium et de magnesium
KR20030080869A (ko) * 2002-04-11 2003-10-17 주식회사 코리아나화장품 아스코르브산 2-글루코시드를 포함하는 피부 미백용화장료 조성물
JP4043312B2 (ja) * 2002-08-06 2008-02-06 株式会社林原生物化学研究所 ２−Ｏ−α−Ｄ−グルコピラノシル−Ｌ−アスコルビン酸の製造方法
KR20040038438A (ko) * 2002-11-01 2004-05-08 주식회사 코리아나화장품 아스코르브산 2-글루코시드 및 송이 추출물을 포함하는피부 미백용 화장료 조성물
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
KR100511419B1 (ko) * 2003-09-15 2005-08-30 한국생명공학연구원 베타-프럭토실-엘-아스코르브산 및 그의 제조방법
WO2006079212A1 (en) 2005-01-26 2006-08-03 Diamedica Inc. Use of s-adenosylmethionme, vitamin e, and vitamin c for the treatment of oxidative liver injury or insulin resistance
JP4766653B2 (ja) * 2005-01-28 2011-09-07 株式会社林原生物化学研究所 眼科用医薬組成物
WO2006090939A1 (en) * 2005-02-23 2006-08-31 Bioland Ltd. Cosmetic composition comprising beta-fructosyl-l-ascorbic acid for skin whitening
MX2007011784A (es) * 2005-03-23 2008-03-14 Mary Kay Inc Composiciones para aclarar la piel.
WO2006137129A1 (ja) * 2005-06-21 2006-12-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo 皮膚外用剤
KR100691540B1 (ko) * 2006-06-22 2007-03-12 주식회사 펩트론 펩타이드가 결합된 안정화된 비타민 ｃ 유도체, 이의제조방법 및 이를 함유하는 조성물
AU2008210290B2 (en) * 2007-02-01 2013-10-31 National Research Council Of Canada Formulations of lipophilic bioactive molecules
EP2152743A2 (de) * 2007-05-23 2010-02-17 Allergan, Inc. Quervernetztes collagen und anwendungen davon
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
CN101541776B (zh) * 2007-09-14 2011-08-03 南京华狮化工有限公司 一种抗坏血酸衍生物、其制备方法和所涉及的中间产物以及该衍生物在化妆品中的应用
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
EP2818184B1 (de) 2007-11-16 2018-10-31 Allergan, Inc. Zusammensetzungen Und Verfahren Zur Behandlung Von Purpura
US8394784B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
WO2010028025A1 (en) 2008-09-02 2010-03-11 Gurtner Geoffrey C Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
JP4885245B2 (ja) * 2009-01-15 2012-02-29 日本航空電子工業株式会社 Ｒｄコンバータ及び角度検出装置
MX2012002696A (es) * 2009-09-03 2012-08-15 Hayashibara Biochem Lab Composicion particulada que contiene ácido 2-0-alfa-d-glucosil-l-a scórbico anhidro cristalino, procedimiento para la producción de la misma, y sus usos.
WO2011030816A1 (ja) * 2009-09-14 2011-03-17 国立大学法人北海道大学 抗植物ウイルス剤
US8927043B2 (en) * 2009-11-10 2015-01-06 Mycell Technologies Stabilized formulations of fatty acids
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110171310A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
EP2544652A2 (de) * 2010-03-12 2013-01-16 Allergan Industrie SAS Fluidzusammensetzung mit einem hyaluronanpolymer und mannitol zur verbesserung des hautzustandes
EP3520827B1 (de) 2010-03-22 2022-05-25 Allergan, Inc. Vernetzte hydrogele zur weichgewebevergrösserung
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
CA2828516C (en) 2011-03-07 2019-05-07 Hayashibara Co., Ltd. Method for producing 2-o-.alpha.-d-glucosyl-l-ascorbic acid anhydrous crystal-containing powder
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9149422B2 (en) 2011-06-03 2015-10-06 Allergan, Inc. Dermal filler compositions including antioxidants
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
EP3590495A1 (de) 2011-08-25 2020-01-08 Allergan, Inc. Dermale füllstoffzusammensetzungen mit antioxidantien
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
WO2014103475A1 (ja) 2012-12-27 2014-07-03 株式会社林原 アンチエイジング用皮膚外用組成物及びその製造方法
CN103755756B (zh) * 2014-02-11 2015-07-08 江苏诚信药业有限公司 一种制备维生素c葡萄糖苷的工艺系统及其工艺方法
EP3200838B1 (de) 2014-09-30 2019-09-18 Allergan Industrie, SAS Stabile hydrogelzusammensetzungen mit additiven
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
WO2016128550A1 (en) 2015-02-13 2016-08-18 Allergan Industrie, Sas Implants for sculpting, augmenting or correcting facial features such as the chin
KR20210034544A (ko) 2018-05-09 2021-03-30 더 존스 홉킨스 유니버시티 향상된 연조직 대체 및 재생을 위한 나노섬유-하이드로겔 복합재료
JP2021522938A (ja) 2018-05-09 2021-09-02 ザ ジョンズ ホプキンス ユニバーシティ 細胞及び組織の送達のためのナノファイバー−ハイドロゲル複合体
WO2020170840A1 (ja) 2019-02-20 2020-08-27 株式会社林原 ２－Ｏ－α－Ｄ－グルコシル－Ｌ－アスコルビン酸のカリウム塩結晶とその製造方法
CN115361945B (zh) 2020-03-31 2024-11-12 浙江养生堂天然药物研究所有限公司 药物组合及其用途
EP4129282A4 (de) 2020-03-31 2024-05-01 Natural Medicine Institute Of Zhejiang Yangshengtang Co., Ltd. Pharmazeutische kombination und verwendung davon
CN115397411B (zh) 2020-04-23 2025-08-22 浙江养生堂天然药物研究所有限公司 药物组合及其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD33788A (de) *
JPS4838158B1 (de) * 1970-10-05 1973-11-15
US4065557A (en) * 1974-03-21 1977-12-27 Bayer Aktiengesellschaft Amino sugars and their use in improving the meat:fat ratio in animals
DD141832A1 (de) * 1978-10-31 1980-05-21 Joachim Schmidt Verfahren und vorrichtung zur herstellung von l-ascorbinsaeure
JPS59501264A (ja) * 1982-06-30 1984-07-19 マサチユ−セツツ　ゼネラル　ホスピタル ビタミンｄグリコシド類
JPS60130582A (ja) * 1983-12-19 1985-07-12 Takeda Chem Ind Ltd 食品用酸化防止剤，アスコルビン酸誘導体およびその製造法
US4822816A (en) * 1987-04-10 1989-04-18 Oxycal Laboratories, Inc. Compositions and methods for administering vitamin C
ATE123306T1 (de) * 1989-05-19 1995-06-15 Hayashibara Biochem Lab Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.
JP2832848B2 (ja) * 1989-10-21 1998-12-09 株式会社林原生物化学研究所 結晶２―Ｏ―α―Ｄ―グルコピラノシル―Ｌ―アスコルビン酸とその製造方法並びに用途

Also Published As

Publication number Publication date
EP0398484B1 (de) 1995-05-31
US5137723A (en) 1992-08-11
EP0398484A2 (de) 1990-11-22
US5616611A (en) 1997-04-01
HK111196A (en) 1996-07-05
ES2075148T3 (es) 1995-10-01
DK0398484T3 (da) 1995-07-24
US5767149A (en) 1998-06-16
DE69019779T2 (de) 1995-12-14
DE69019779D1 (de) 1995-07-06
EP0398484A3 (de) 1991-02-27

Similar Documents

Publication Publication Date Title
ATE123306T1 (de) Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.
FR2634376B1 (fr) Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
IL87488A0 (en) Pharmaceutical compositions for the topical treatment of conditions associated with photodamaged skin,comprising substituted propenyl phenyl derivatives
BR9910251A (pt) Estimulação hematopoiética
CA2225797A1 (en) Active principle carriers containing non-ionic surfactants, and uses thereof, particularly in food, cosmetics and pharmaceuticals
HUT61031A (en) Process for producing chemically modified, stable haemoglobin substituting for non-immunogehic red blood cell, and pharmaceutical compositions comprising same as active ingredient
YU174490A (sh) Novi estri tienil-karboksilne kiseline sa aminoalkoholima, njihova kvaterna jedinjenja kao i pripremanje i primena tih jedinjenja
AU8281387A (en) Cosmetic composition
IE873125L (en) Benzimidazole derivatives
CA2022177A1 (en) Arginine deiminase, its manufacturing method, and an anti-cancer agent containing this enzyme as an effective ingredient
DE69130719D1 (de) Aktive antioxidierende Substanz und ihre Verwendung
ES8800982A1 (es) Un metodo para producir la enzima superoxido-dismutasa modificada con derivados de polietilenglicol y triazina.
KR970009581B1 (en) Composition for topical use containing depolymerized deoxyribonucleic acids in the skin and body cosmetic treathent
IT1224405B (it) Composti attivi sul sistema cardiovascolare
JPS6434909A (en) Cosmetic
EP0246569A3 (de) Superoxide Dismutase-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzung
ATE102019T1 (de) Mittel zur kosmetischen oder pharmazeutischen verwendung.
AU629445B2 (en) Improvements in or relating to topical compositions containing 1 alpha 25-dihydroxycholecalciferol
EP0310126A3 (en) Derivatives of pyrocatechol-carboxylic acid, their preparation and use as active ingredients in medicines
BR9808913A (pt) Processo para a preparação de artigos moldados compactos ou celulares semiduros á base de pur e sua estabilização, artigos moldados preparados dos mesmos, bem como seu emprego
DE69010518D1 (de) Wässerige Desmopressin-CMC enthaltende Arzneizubereitung.
EP0314042A3 (de) Copolymere und mit diesen Copolymeren modifizierte Superoxid-Dismutase
FR2567402B1 (fr) Nouvelles compositions pharmaceutiques et cosmetiques contenant comme ingredient actif la dihydroxy-1,8 phenyl-10 anthrone-9, et procede de preparation de l'ingredient actif
KR910000131A (ko) 생리학적 투여량의 비타민a와 치료학적 활성이 있는 각종 활성소의 군집
FR2657258B1 (de)

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee