ATE123487T1 - Derivate der kaffeinsäure und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents
Derivate der kaffeinsäure und sie enthaltende pharmazeutische zusammensetzungen.Info
- Publication number
- ATE123487T1 ATE123487T1 AT91114615T AT91114615T ATE123487T1 AT E123487 T1 ATE123487 T1 AT E123487T1 AT 91114615 T AT91114615 T AT 91114615T AT 91114615 T AT91114615 T AT 91114615T AT E123487 T1 ATE123487 T1 AT E123487T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- derivatives
- alkyl group
- pharmaceutical compositions
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000041 C6-C10 aryl group Chemical group 0.000 abstract 1
- -1 C7-C12 aralkyl Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical class OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/23—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same unsaturated acyclic carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22649390 | 1990-08-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE123487T1 true ATE123487T1 (de) | 1995-06-15 |
Family
ID=16845971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91114615T ATE123487T1 (de) | 1990-08-30 | 1991-08-30 | Derivate der kaffeinsäure und sie enthaltende pharmazeutische zusammensetzungen. |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US5232941A (de) |
| EP (1) | EP0475214B1 (de) |
| JP (1) | JPH05331129A (de) |
| AT (1) | ATE123487T1 (de) |
| DE (1) | DE69110217T2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5393913A (en) * | 1993-03-03 | 1995-02-28 | Rhone-Poulenc Inc. | N-formylanilines |
| US6831191B2 (en) | 2001-12-20 | 2004-12-14 | Em Industries | Photo stable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom |
| US6602515B2 (en) | 2001-07-16 | 2003-08-05 | Em Industries | Photo stable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom |
| JP2005526026A (ja) * | 2002-02-06 | 2005-09-02 | イシウム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ イエルサレム | カテコール生物学的等価体 |
| US6699463B2 (en) | 2002-04-10 | 2004-03-02 | Em Industries | Photostable cationic organic sunscreen compounds with antioxidant properties and compositions obtained therefrom |
| US6936735B2 (en) * | 2002-08-27 | 2005-08-30 | Emd Chemicals, Inc. | Photostable cationic organic sunscreen compounds and compositions obtained therefrom |
| US7368249B2 (en) * | 2003-07-24 | 2008-05-06 | The Curators Of The University Of Missouri | Methods and compositions for evaluation and modulation of fertility |
| WO2008083389A1 (en) * | 2006-12-29 | 2008-07-10 | Moleculin, L.L.C. | Methods of treating skin disorders with caffeic acid analogs |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68917357T2 (de) * | 1988-04-28 | 1995-01-26 | Suntory Ltd | Derivate der Coffeinsäure und pharmazeutische Zusammensetzungen, die sie enthalten. |
-
1991
- 1991-08-21 JP JP3232523A patent/JPH05331129A/ja active Pending
- 1991-08-27 US US07/750,396 patent/US5232941A/en not_active Expired - Fee Related
- 1991-08-30 EP EP91114615A patent/EP0475214B1/de not_active Expired - Lifetime
- 1991-08-30 DE DE69110217T patent/DE69110217T2/de not_active Expired - Fee Related
- 1991-08-30 AT AT91114615T patent/ATE123487T1/de active
-
1993
- 1993-03-31 US US08/040,604 patent/US5326785A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5232941A (en) | 1993-08-03 |
| DE69110217T2 (de) | 1996-02-29 |
| EP0475214A1 (de) | 1992-03-18 |
| EP0475214B1 (de) | 1995-06-07 |
| JPH05331129A (ja) | 1993-12-14 |
| DE69110217D1 (de) | 1995-07-13 |
| US5326785A (en) | 1994-07-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK490288A (da) | Substituerede thiazolidindionderivater | |
| NO159017C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 1,2,3,4-tetrahydroisokinolin-3-karboksylsyre-derivater. | |
| ATE52498T1 (de) | Amidderivate. | |
| ATE79376T1 (de) | Dithioacetal-verbindungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| DE68917357D1 (de) | Derivate der Coffeinsäure und pharmazeutische Zusammensetzungen, die sie enthalten. | |
| ATE8144T1 (de) | Indolobenzoxazine, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen. | |
| NO881835D0 (no) | Fremgangsmaate for fremstilling av terapeutisk aktive bicykliske forbindelser. | |
| DE69110217D1 (de) | Derivate der Kaffeinsäure und sie enthaltende pharmazeutische Zusammensetzungen. | |
| IL85768A (en) | Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them | |
| DE69102352D1 (de) | N-Benzyl-N1-phenyl und -phenalkyl-thioharnstoffe. | |
| ATE5961T1 (de) | N-acylpeptid-verbindungen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
| DK148288D0 (da) | N-phenethylaminoalkyl-benzamid-forbindelser, deres anvendelse til fremstilling af antiarrhythmia-laegemidler og farmaceutiske praeparater indeholdende forbindelserne | |
| ATE18211T1 (de) | Chinolinessigsaeuren und diese enthaltende pharmazeutische zubereitungen. | |
| ATE168995T1 (de) | N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen | |
| NO903084D0 (no) | Farmasoeytisk anvendbare thiazol-derivater og fremgangsmaate for deres fremstilling. | |
| DE69024154D1 (de) | Pyrimidoindolderivate und Verfahren zu ihrer Herstellung | |
| DE69016378D1 (de) | Substituierte Benzothiazolinone, ihre Herstellung und sie enthaltende pharmazeutische Zusammenstellungen. | |
| ATE1585T1 (de) | Clavulansaeurederivate, ihre herstellung und sie enthaltende pharmazeutische praeparate. |