ATE168995T1 - N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen - Google Patents

N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen

Info

Publication number: ATE168995T1
Authority: AT; Austria
Prior art keywords: radical; aryl; preparation; pharmaceutical compositions; alkyl
Prior art date: 1991-10-25

Application number

AT92921688T

Other languages

English (en)

Inventor

Marie-Claude Fournie-Zaluski

Bernard Pierre Roques

Original Assignee

Inst Nat Sante Rech Med

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-25

Filing date

1992-10-21

Publication date

1998-08-15

1992-10-21 Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med

1998-08-15 Application granted granted Critical

1998-08-15 Publication of ATE168995T1 publication Critical patent/ATE168995T1/de

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
150000001413 amino acids Chemical class 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
125000003118 aryl group Chemical group 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
229910052799 carbon Inorganic materials 0.000 abstract 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000003435 aroyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
150000001721 carbon Chemical group 0.000 abstract 1
125000001325 propanoyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT92921688T 1991-10-25 1992-10-21 N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen ATE168995T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9113174A FR2682952B1 (fr)	1991-10-25	1991-10-25	Nouveaux n-(mercaptoacyl) amino-acides, leur preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number	Publication Date
ATE168995T1 true ATE168995T1 (de)	1998-08-15

Family

ID=9418304

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92921688T ATE168995T1 (de)	1991-10-25	1992-10-21	N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen

Country Status (11)

Country	Link
EP (2)	EP0609310B1 (de)
JP (2)	JP3250806B2 (de)
AT (1)	ATE168995T1 (de)
AU (1)	AU666141B2 (de)
CA (1)	CA2121801A1 (de)
DE (1)	DE69226443T2 (de)
DK (1)	DK0609310T3 (de)
ES (1)	ES2118833T3 (de)
FR (1)	FR2682952B1 (de)
MX (1)	MX9206149A (de)
WO (1)	WO1993008162A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1273455B (it) *	1995-01-27	1997-07-08	Zambon Spa	Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
FR2731219B1 (fr) *	1995-03-03	1997-04-25	Bioprojet Soc Civ	Procede de synthese d'acides acryliques alpha-substitues et leur application
IT1277736B1 (it) *	1995-12-28	1997-11-12	Zambon Spa	Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
IT1277737B1 (it) *	1995-12-28	1997-11-12	Zambon Spa	Derivati tiolici ad attivita' inibitrice delle metallopeptidasi

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2480747A1 (fr)	1980-04-17	1981-10-23	Roques Bernard	Derives d'acides amines et leur application therapeutique
US4401677A (en)	1981-10-09	1983-08-30	E. R. Squibb & Sons, Inc.	Enkephalinase inhibitors
DE3467754D1 (de) *	1983-10-03	1988-01-07	Squibb & Sons Inc	Enkephalinase inhibitors
US4740499A (en)	1986-07-28	1988-04-26	Monsanto Company	Method of enhancing the bioactivity of atrial peptides
FR2617070A2 (fr) *	1987-03-23	1988-12-30	Collet Claude	Appareil de prehension, type mandrin, entierement automatique, a commandes d'ouverture et de fermeture ultra-rapides
CA1337400C (en) *	1987-06-08	1995-10-24	Norma G. Delaney	Inhibitors of neutral endopeptidase
US4879309A (en) *	1988-09-27	1989-11-07	Schering Corporation	Mercapto-acylamino acids as antihypertensives

1991
- 1991-10-25 FR FR9113174A patent/FR2682952B1/fr not_active Expired - Fee Related
1992
- 1992-10-21 EP EP92921688A patent/EP0609310B1/de not_active Expired - Lifetime
- 1992-10-21 AT AT92921688T patent/ATE168995T1/de not_active IP Right Cessation
- 1992-10-21 EP EP92117955A patent/EP0539848A1/de active Pending
- 1992-10-21 JP JP50744693A patent/JP3250806B2/ja not_active Expired - Fee Related
- 1992-10-21 AU AU27895/92A patent/AU666141B2/en not_active Ceased
- 1992-10-21 CA CA002121801A patent/CA2121801A1/en not_active Abandoned
- 1992-10-21 ES ES92921688T patent/ES2118833T3/es not_active Expired - Lifetime
- 1992-10-21 DK DK92921688T patent/DK0609310T3/da active
- 1992-10-21 DE DE69226443T patent/DE69226443T2/de not_active Expired - Fee Related
- 1992-10-21 WO PCT/EP1992/002412 patent/WO1993008162A1/en not_active Ceased
- 1992-10-23 MX MX9206149A patent/MX9206149A/es unknown
2001
- 2001-05-24 JP JP2001155490A patent/JP2002030066A/ja not_active Abandoned

Also Published As

Publication number	Publication date
EP0539848A1 (de)	1993-05-05
JPH07509441A (ja)	1995-10-19
FR2682952B1 (fr)	1993-12-03
JP3250806B2 (ja)	2002-01-28
WO1993008162A1 (en)	1993-04-29
DK0609310T3 (da)	1999-04-26
DE69226443D1 (de)	1998-09-03
DE69226443T2 (de)	1999-02-04
JP2002030066A (ja)	2002-01-29
FR2682952A1 (fr)	1993-04-30
AU666141B2 (en)	1996-02-01
AU2789592A (en)	1993-05-21
MX9206149A (es)	1993-08-01
EP0609310B1 (de)	1998-07-29
EP0609310A1 (de)	1994-08-10
CA2121801A1 (en)	1993-04-29
ES2118833T3 (es)	1998-10-01

Legal Events

Date	Code	Title	Description
2004-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE10199003I2 (de)	2003-09-18
GB8919434D0 (en)	1989-10-11	Novel compounds
ATE68180T1 (de)	1991-10-15	Morpholinoethylester von mycophenolsaeure und ihre derivate, ihre herstellung und verwendung in pharmazeutische zusammensetzungen.
ATE52498T1 (de)	1990-05-15	Amidderivate.
DE3372707D1 (en)	1987-09-03	Spiro-(4,(3+n))-2-aza-alkan-3-carboxylic-acid derivatives, process for their preparation,agents containing them and their use
ATE109770T1 (de)	1994-08-15	Derivate der coffeinsäure und pharmazeutische zusammensetzungen, die sie enthalten.
IL85768A (en)	1993-02-21	Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them
ATE168995T1 (de)	1998-08-15	N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen
ATE123487T1 (de)	1995-06-15	Derivate der kaffeinsäure und sie enthaltende pharmazeutische zusammensetzungen.
ATE106734T1 (de)	1994-06-15	Pharmazeutische zusammensetzung zur verhinderung der plättchenaggregation.
CY1970A (en)	1997-09-05	Pharmaceutical preparations
GB8515212D0 (en)	1985-07-17	Thiazolidine derivatives
DE69011235D1 (de)	1994-09-08	Derivate von N-(Vincristinyl-23) und N-(Noranhydro-5-vinblastinyl-23) von Amino-1-methylphosphonsäure, ihre Verfahren zur Herstellung und sie enthaltende pharmazeutische Zusammensetzungen.
ATE87004T1 (de)	1993-04-15	Fluor enthaltende makrolid-verbindungen, pharmazeutische zusammensetzungen, welche diese enthalten und ihre verwendung fuer die herstellung von arzneimitteln.