ATE125299T1 - Synthetisches gen für menschliches parathyroidhormon. - Google Patents
Synthetisches gen für menschliches parathyroidhormon.Info
- Publication number
- ATE125299T1 ATE125299T1 AT91116281T AT91116281T ATE125299T1 AT E125299 T1 ATE125299 T1 AT E125299T1 AT 91116281 T AT91116281 T AT 91116281T AT 91116281 T AT91116281 T AT 91116281T AT E125299 T1 ATE125299 T1 AT E125299T1
- Authority
- AT
- Austria
- Prior art keywords
- dna
- parathyroid hormone
- human parathyroid
- synthetic gene
- producing
- Prior art date
Links
- 101001135770 Homo sapiens Parathyroid hormone Proteins 0.000 title abstract 4
- 101001135995 Homo sapiens Probable peptidyl-tRNA hydrolase Proteins 0.000 title abstract 4
- 102000058004 human PTH Human genes 0.000 title abstract 4
- 108700005078 Synthetic Genes Proteins 0.000 title abstract 2
- 108020004414 DNA Proteins 0.000 abstract 5
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 229940046166 oligodeoxynucleotide Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25749190 | 1990-09-28 | ||
| JP5643491 | 1991-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE125299T1 true ATE125299T1 (de) | 1995-08-15 |
Family
ID=26397380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91116281T ATE125299T1 (de) | 1990-09-28 | 1991-09-25 | Synthetisches gen für menschliches parathyroidhormon. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5714349A (de) |
| EP (1) | EP0483509B1 (de) |
| AT (1) | ATE125299T1 (de) |
| CA (1) | CA2052396C (de) |
| DE (1) | DE69111371T2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05271279A (ja) * | 1991-08-07 | 1993-10-19 | Takeda Chem Ind Ltd | ヒト副甲状腺ホルモンムテインおよびその製造法 |
| US5814603A (en) * | 1992-06-12 | 1998-09-29 | Affymax Technologies N.V. | Compounds with PTH activity |
| KR100230578B1 (ko) * | 1997-07-25 | 1999-12-01 | 허영섭 | 포스포리불로키나제를 융합파트너로 이용하는 재조합 인간 부갑상선호르몬의 발현벡터 |
| CN1301740A (zh) * | 1999-12-24 | 2001-07-04 | 上海博德基因开发有限公司 | 一种新的多肽——甲状旁腺激素9和编码这种多肽的多核苷酸 |
| US6818752B2 (en) * | 2000-01-31 | 2004-11-16 | Biocatalytics, Inc. | Synthetic genes for enhanced expression |
| US6756480B2 (en) | 2000-04-27 | 2004-06-29 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
| CA2694562A1 (en) | 2007-08-09 | 2009-02-12 | Usv Limited | Novel orthogonal process for purification of recombinant human parathyroid hormone (rhpth) (1-34) |
| KR102011291B1 (ko) | 2018-12-05 | 2019-10-21 | 주식회사 펩진 | 신규한 융합 폴리펩타이드 및 이를 이용하여 인간 부갑상선 호르몬 1-34를 생산하는 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0178863A1 (de) * | 1984-10-15 | 1986-04-23 | Schering Corporation | Expressionssysteme die sich der Bakteriophage-T7-Promotoren bedienen und Gensequenzen |
| US5010010A (en) * | 1986-10-22 | 1991-04-23 | Selmer-Sande, A.S. | Production of human parathyroid hormone from microorganisms |
| EP0604706A1 (de) * | 1986-10-22 | 1994-07-06 | GAUTVIK, Kaare M., Dr. | Herstellung von humanem Parathormon mittels Mikroorganismen |
| WO1991005050A1 (en) * | 1989-09-29 | 1991-04-18 | Her Majesty In Right Of Canada As Represented By The National Research Council Of Canada | Synthesis of mature human parathyroid hormone |
-
1991
- 1991-09-25 AT AT91116281T patent/ATE125299T1/de active
- 1991-09-25 EP EP91116281A patent/EP0483509B1/de not_active Expired - Lifetime
- 1991-09-25 DE DE69111371T patent/DE69111371T2/de not_active Expired - Fee Related
- 1991-09-27 CA CA002052396A patent/CA2052396C/en not_active Expired - Fee Related
-
1996
- 1996-08-05 US US08/689,190 patent/US5714349A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2052396A1 (en) | 1992-03-29 |
| DE69111371D1 (de) | 1995-08-24 |
| EP0483509A1 (de) | 1992-05-06 |
| EP0483509B1 (de) | 1995-07-19 |
| US5714349A (en) | 1998-02-03 |
| DE69111371T2 (de) | 1996-03-14 |
| CA2052396C (en) | 2002-02-05 |
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