ATE182174T1 - Gliazellen-aktivierender faktor und dessen herstellung - Google Patents

Gliazellen-aktivierender faktor und dessen herstellung

Info

Publication number
ATE182174T1
ATE182174T1 AT92102385T AT92102385T ATE182174T1 AT E182174 T1 ATE182174 T1 AT E182174T1 AT 92102385 T AT92102385 T AT 92102385T AT 92102385 T AT92102385 T AT 92102385T AT E182174 T1 ATE182174 T1 AT E182174T1
Authority
AT
Austria
Prior art keywords
activating factor
glia activating
glia
production
cell activation
Prior art date
Application number
AT92102385T
Other languages
English (en)
Inventor
Ken-Ichi Naruo
Chisako Seko
Tsutomu Kurokawa
Tatsuya Kondo
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE182174T1 publication Critical patent/ATE182174T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT92102385T 1991-02-14 1992-02-13 Gliazellen-aktivierender faktor und dessen herstellung ATE182174T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2086091 1991-02-14
JP22445491 1991-09-04
JP00339992A JP3385040B2 (ja) 1991-02-14 1992-01-10 グリア活性化因子およびその製造法

Publications (1)

Publication Number Publication Date
ATE182174T1 true ATE182174T1 (de) 1999-07-15

Family

ID=27275805

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92102385T ATE182174T1 (de) 1991-02-14 1992-02-13 Gliazellen-aktivierender faktor und dessen herstellung

Country Status (6)

Country Link
US (2) US5512460A (de)
EP (1) EP0503297B1 (de)
JP (1) JP3385040B2 (de)
AT (1) ATE182174T1 (de)
CA (1) CA2061148C (de)
DE (1) DE69229572T2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6811989B1 (en) * 1989-02-17 2004-11-02 Bayer Corporation Pancreatic islet cell antigens obtained by molecular cloning
US5840836A (en) * 1989-02-17 1998-11-24 Bayer Corporation Pancreatic islet cell antigens obtained by molecular cloning
EP0585631A1 (de) * 1992-08-05 1994-03-09 Takeda Chemical Industries, Ltd. Blutplättchen vermehrendes Agens
EP0608546A3 (en) * 1992-12-22 1995-09-27 Takeda Chemical Industries Ltd Glia activating factor (gaf), antibodies against it and their uses.
EP0613946B1 (de) * 1993-02-12 2003-05-28 Takeda Chemical Industries, Ltd. HST-2 Mutein, dafür kodierende DNS und Herstellung
US5922572A (en) * 1994-01-25 1999-07-13 Human Genome Sciences, Inc. Polynucleotides encoding haemopoietic maturation factor
IL122473A (en) * 1995-06-12 2003-11-23 Yeda Res & Dev Fgfr3 as a marker for mesenchymal skeletal progenitor cells
US5731284A (en) * 1995-09-28 1998-03-24 Amgen Inc. Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product
WO1998029547A1 (en) * 1996-12-31 1998-07-09 The Rockefeller University Modulators of radial glia-astrocyte differentiation and transformation, and diagnostic and therapeutic uses thereof
AU8999298A (en) * 1997-09-08 1999-03-29 Taisho Pharmaceutical Co., Ltd. Protein having activity of activiting nerve cell functions
US20010006939A1 (en) * 1997-10-03 2001-07-05 Ralph W. Niven Secretory leukocyte protease inhibitor dry powder pharmaceutical compositions
US20020058036A1 (en) * 1999-07-27 2002-05-16 Michael Jeffers Novel fibroblast growth factor and nucleic acids encoding same
US7056885B1 (en) * 1999-07-27 2006-06-06 Curagen Corporation Fibroblast growth factor and nucleic acids encoding same
US7291483B2 (en) 1999-07-27 2007-11-06 Curagen Corporation FGF-CX polynucleotide sequences and methods of producing same
IL139380A0 (en) * 2000-10-31 2001-11-25 Prochon Biotech Ltd Active variants of fibroblast growth factor
US6982250B2 (en) 2000-11-06 2006-01-03 Curagen Corporation Methods of prevention and treatment of inflammatory bowel disease
IL149562A0 (en) * 2002-05-09 2002-11-10 Prochon Ltd Fgf variants and methods for use thereof
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
WO2008038287A2 (en) 2006-09-28 2008-04-03 Hepacore Ltd. N-terminal fgf variants having increased receptor selectivity and uses thereof
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
CA2717725A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
WO2012038953A2 (en) 2010-09-21 2012-03-29 Hepacore Ltd. Fgf-18 truncated variants having increased receptor specificity and uses thereof
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
JP7488571B2 (ja) 2018-11-08 2024-05-22 インテグリカルチャー株式会社 動物細胞増殖促進剤、動物細胞培養用培地及び動物細胞培養装置

Also Published As

Publication number Publication date
US5512460A (en) 1996-04-30
EP0503297A1 (de) 1992-09-16
EP0503297B1 (de) 1999-07-14
CA2061148C (en) 2004-08-24
DE69229572T2 (de) 1999-11-11
JP3385040B2 (ja) 2003-03-10
CA2061148A1 (en) 1992-08-15
JPH05301893A (ja) 1993-11-16
US5622928A (en) 1997-04-22
DE69229572D1 (de) 1999-08-19

Similar Documents

Publication Publication Date Title
DE69229572D1 (de) Gliazellen-aktivierender Faktor und dessen Herstellung
Nash et al. Culture media.
DE69019609D1 (de) Proteine und deren Herstellung.
CA2127463A1 (en) Biodegradable polymers for cell transplantation
EP0404034A3 (de) DNS und ihre Verwendung
CA2066618A1 (en) Plasmids containing dna encoding the amino acid sequence of tcf-ii, transformed cells with the plasmids, and production method of biologically active substance using the transformed cells
DE68922869D1 (de) Rezeptor-Proteine für humanen B-Zellen stimulierenden Faktor 2.
ATE45382T1 (de) Biosynthetisch hergestellter humannervenwachstumsfaktor, verfahren zu seiner herstellung, diesen faktor enthaltende zusammensetzungen, diesen faktor codierende dna- sequenz, vektoren, die diese sequenz enthalten und dadurch transformierte wirtszellen.
EP0343783A3 (en) Method for producing cells containing stably integrated foreign dna at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign dna
EP0546110A4 (en) New insulin-like growth factor binding protein igfbp-5
ATE501254T1 (de) P- selectin ligandenprotein
CA2180103A1 (en) Gene encoding adseverin
DE3678609D1 (de) Partikel mit immunogenen hbs-antigen-eigenschaften und mit einer mit dem hbs-antigen-epitopen nichtverwandten antigenischen stelle, vektoren und tierische zellen fuer die herstellung dieser kombinierten impfstoffartikel.
IL92669A0 (en) Tgf-beta 1/beta 2:a novel chimeric transforming growth factor-beta
ATE111521T1 (de) Polypeptid und dessen herstellung.
DE3485336D1 (de) Verfahren zur expression von alpha-1-antitrypsin in bakterien und dessen verwendung in therapeutischen zusammensetzungen sowie vektoren und bakterien fuer ein solches verfahren und deren herstellung.
WO1995030001A3 (en) Novel p-selectin ligand protein
DE69430975D1 (de) Verfahren zur Herstellung von Proteinen
EP0542222A3 (en) Process for producing trans-l-hydroxyproline
EP0251730A3 (de) Herstellung von menschlichem Lysozym
DE69305826D1 (de) Verfahren zur Herstellung von Alkalimetallcitrat
DE3854420D1 (de) Onkogen kodierendes polypeptid, das wachstumsfaktoraktivität besitzt, verfahren zu seiner herstellung und verwendung.
GR3020790T3 (en) Achromobacter protease I gene and gene product thereof
RU96121465A (ru) Биосинтез рибофлавина в грибах
CA2080008A1 (en) Water-soluble mutein of fibroblast growth factor (fgf) receptor