ATE125697T1 - Koppelung des wachstumshormons an liposomen. - Google Patents
Koppelung des wachstumshormons an liposomen.Info
- Publication number
- ATE125697T1 ATE125697T1 AT92905800T AT92905800T ATE125697T1 AT E125697 T1 ATE125697 T1 AT E125697T1 AT 92905800 T AT92905800 T AT 92905800T AT 92905800 T AT92905800 T AT 92905800T AT E125697 T1 ATE125697 T1 AT E125697T1
- Authority
- AT
- Austria
- Prior art keywords
- egf
- liposomes
- coupling
- growth hormone
- crosslinking
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 3
- 102000018997 Growth Hormone Human genes 0.000 title 1
- 108010051696 Growth Hormone Proteins 0.000 title 1
- 230000008878 coupling Effects 0.000 title 1
- 238000010168 coupling process Methods 0.000 title 1
- 238000005859 coupling reaction Methods 0.000 title 1
- 239000000122 growth hormone Substances 0.000 title 1
- 102000009024 Epidermal Growth Factor Human genes 0.000 abstract 5
- UWFRVQVNYNPBEF-UHFFFAOYSA-N 1-(2,4-dimethylphenyl)propan-1-one Chemical compound CCC(=O)C1=CC=C(C)C=C1C UWFRVQVNYNPBEF-UHFFFAOYSA-N 0.000 abstract 1
- 101800003838 Epidermal growth factor Proteins 0.000 abstract 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 abstract 1
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 150000001412 amines Chemical group 0.000 abstract 1
- 238000004132 cross linking Methods 0.000 abstract 1
- 239000003431 cross linking reagent Substances 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 229940116977 epidermal growth factor Drugs 0.000 abstract 1
- 150000008104 phosphatidylethanolamines Chemical class 0.000 abstract 1
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65557691A | 1991-02-14 | 1991-02-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE125697T1 true ATE125697T1 (de) | 1995-08-15 |
Family
ID=24629451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92905800T ATE125697T1 (de) | 1991-02-14 | 1991-10-30 | Koppelung des wachstumshormons an liposomen. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0525163B1 (de) |
| JP (1) | JPH05506251A (de) |
| AT (1) | ATE125697T1 (de) |
| AU (1) | AU649796B2 (de) |
| CA (1) | CA2079443C (de) |
| DE (1) | DE69111804T2 (de) |
| DK (1) | DK0525163T3 (de) |
| ES (1) | ES2077403T3 (de) |
| WO (1) | WO1992014448A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5603872A (en) * | 1991-02-14 | 1997-02-18 | Baxter International Inc. | Method of binding recognizing substances to liposomes |
| US6326353B1 (en) * | 1993-03-23 | 2001-12-04 | Sequus Pharmaceuticals, Inc. | Enhanced circulation effector composition and method |
| DE69732308T2 (de) | 1996-09-27 | 2005-06-02 | Jagotec Ag | Arzneistoffverabreichungssystem mit hyaluronsäure |
| JP5250229B2 (ja) * | 2007-09-25 | 2013-07-31 | 独立行政法人科学技術振興機構 | カーボンナノホーン |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5064655A (en) * | 1989-02-24 | 1991-11-12 | Liposome Technology, Inc. | Liposome gel composition and method |
-
1991
- 1991-10-30 ES ES92905800T patent/ES2077403T3/es not_active Expired - Lifetime
- 1991-10-30 DK DK92905800.6T patent/DK0525163T3/da active
- 1991-10-30 CA CA002079443A patent/CA2079443C/en not_active Expired - Fee Related
- 1991-10-30 AU AU13478/92A patent/AU649796B2/en not_active Ceased
- 1991-10-30 AT AT92905800T patent/ATE125697T1/de not_active IP Right Cessation
- 1991-10-30 DE DE69111804T patent/DE69111804T2/de not_active Expired - Fee Related
- 1991-10-30 WO PCT/US1991/008114 patent/WO1992014448A1/en not_active Ceased
- 1991-10-30 JP JP92505659A patent/JPH05506251A/ja active Pending
- 1991-10-30 EP EP92905800A patent/EP0525163B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69111804D1 (de) | 1995-09-07 |
| JPH05506251A (ja) | 1993-09-16 |
| WO1992014448A1 (en) | 1992-09-03 |
| EP0525163B1 (de) | 1995-08-02 |
| DE69111804T2 (de) | 1996-05-02 |
| AU649796B2 (en) | 1994-06-02 |
| DK0525163T3 (da) | 1995-09-25 |
| ES2077403T3 (es) | 1995-11-16 |
| CA2079443C (en) | 2002-12-31 |
| EP0525163A1 (de) | 1993-02-03 |
| AU1347892A (en) | 1992-09-15 |
| CA2079443A1 (en) | 1992-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |