ATE127014T1 - Verfahren zur herstellung von vesikeln. - Google Patents

Verfahren zur herstellung von vesikeln.

Info

Publication number
ATE127014T1
ATE127014T1 AT90903531T AT90903531T ATE127014T1 AT E127014 T1 ATE127014 T1 AT E127014T1 AT 90903531 T AT90903531 T AT 90903531T AT 90903531 T AT90903531 T AT 90903531T AT E127014 T1 ATE127014 T1 AT E127014T1
Authority
AT
Austria
Prior art keywords
film
producing vesicles
agitation
homogeneous
evaporation
Prior art date
Application number
AT90903531T
Other languages
English (en)
Inventor
Kevin R Bracken
Original Assignee
Vestar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestar Inc filed Critical Vestar Inc
Application granted granted Critical
Publication of ATE127014T1 publication Critical patent/ATE127014T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/22—Evaporating by bringing a thin layer of the liquid into contact with a heated surface
    • B01D1/222—In rotating vessels; vessels with movable parts
    • B01D1/223—In rotating vessels; vessels with movable parts containing a rotor
    • B01D1/225—In rotating vessels; vessels with movable parts containing a rotor with blades or scrapers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT90903531T 1989-01-27 1990-01-22 Verfahren zur herstellung von vesikeln. ATE127014T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/303,473 US4935171A (en) 1989-01-27 1989-01-27 Method for vesicle formation

Publications (1)

Publication Number Publication Date
ATE127014T1 true ATE127014T1 (de) 1995-09-15

Family

ID=23172272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90903531T ATE127014T1 (de) 1989-01-27 1990-01-22 Verfahren zur herstellung von vesikeln.

Country Status (9)

Country Link
US (1) US4935171A (de)
EP (1) EP0457833B1 (de)
JP (1) JPH04504527A (de)
AT (1) ATE127014T1 (de)
AU (1) AU5103990A (de)
DE (1) DE69022034T2 (de)
DK (1) DK0457833T3 (de)
ES (1) ES2075894T3 (de)
WO (1) WO1990008535A1 (de)

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US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5830498A (en) * 1987-10-16 1998-11-03 Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5096629A (en) * 1988-08-29 1992-03-17 501 Nippon Fine Chemical Co., Ltd. Method for preparing lipid powder for use in preparing liposomes and method for preparing liposomes
US5236355A (en) * 1988-12-22 1993-08-17 American Cyanamid Company Apparatus for the treatment of periodontal disease
EP0374531B1 (de) * 1988-12-22 1994-05-04 American Cyanamid Company Verfahren zur Behandlung von Periodontitis durch protrahierte Wirkstoffabgabe von Arzneimitteln in der Zahnhöhle, Zusammensetzung davon und Vorrichtung zur Verabreichung
US6004534A (en) * 1993-07-23 1999-12-21 Massachusetts Institute Of Technology Targeted polymerized liposomes for improved drug delivery
WO1995003035A1 (en) * 1993-07-23 1995-02-02 Massachusetts Institute Of Technology Polymerized liposomes with enhanced stability for oral delivery
AU728176B2 (en) 1995-05-04 2001-01-04 Gilead Sciences, Inc. Nucleic acid ligand complexes
US6120795A (en) * 1996-03-27 2000-09-19 Ortho Pharmaceutical Corp. Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation
US6060082A (en) 1997-04-18 2000-05-09 Massachusetts Institute Of Technology Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
JP4808842B2 (ja) * 1997-08-18 2011-11-02 ジーイー・ヘルスケア・アクスイェ・セルスカプ 小胞の調製方法
US6855296B1 (en) 1998-11-13 2005-02-15 Optime Therapeutics, Inc. Method and apparatus for liposome production
WO2000029103A1 (en) * 1998-11-13 2000-05-25 Optime Therapeutics, Inc. Method and apparatus for liposome production
US6160143A (en) * 2000-02-18 2000-12-12 Artisan Industries Inc. Method for the concentration and separation of sterols
WO2002012790A1 (de) * 2000-08-09 2002-02-14 Rational Ag Verfahren und vorrichtung zum erzeugen von dampf, insbesondere für ein gargerät
US20110142922A1 (en) * 2002-04-30 2011-06-16 Ferndale Ip, Inc. Stabilized composition and method for dermatological treatment
AU2003298738A1 (en) * 2002-11-26 2004-06-18 Su-Ming Chiang Liposomal formulations
US7192989B2 (en) * 2002-12-20 2007-03-20 Akzo Nobel N.V. Method and expansion device for preparing expanded thermoplastic microspheres
DE102005002469B3 (de) * 2005-01-18 2006-05-11 Abnoba Heilmittel Gmbh Verfahren und Vorrichtungen zur Einkapselung von Stoffen in Liposomen mit frei einstellbarem Membranaufbau
US20070166386A1 (en) * 2006-01-13 2007-07-19 Chinea Vanessa I Nanoparticle formation of pharmaceutical ingredients
JP2009533455A (ja) * 2006-04-12 2009-09-17 マサチューセッツ インスティテュート オブ テクノロジー 癒着を阻害するための組成物および方法
EP2196194B1 (de) * 2007-09-10 2017-08-09 M Technique Co., Ltd. Verfahren zur erzeugung von biologischen ingesta und damit erhaltene biologische ingesta
AU2009236585B2 (en) 2008-04-18 2013-03-07 Vaxinnate Corporation Deletion mutants of flagellin and methods of use
JP6061343B2 (ja) * 2011-04-04 2017-01-18 学校法人早稲田大学 小胞体の製造方法
WO2012138867A2 (en) 2011-04-07 2012-10-11 The Board Of Trustees Of The Leland Stanford Junior University Long-acting peptide analogs
GB201204384D0 (en) 2012-03-13 2012-04-25 Univ Dundee Anti-flammatory agents
WO2016191547A1 (en) 2015-05-26 2016-12-01 Comfort Care For Animals Llc Liposome loading
CN115551626A (zh) * 2020-04-07 2022-12-30 V·E·麦克卢尔 用于聚合物的液相催化热解的反应容器
WO2024216279A2 (en) * 2023-04-13 2024-10-17 University Of Connecticut Analgesic compounds comprising charged particles and method of manufacture thereof

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US2812019A (en) * 1954-09-22 1957-11-05 Rodney Hunt Machine Co Treatment of lecithin
US2863888A (en) * 1954-09-28 1958-12-09 Colgate Palmolive Co Process for the production of fatty acid hydroxy amides
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US4485054A (en) * 1982-10-04 1984-11-27 Lipoderm Pharmaceuticals Limited Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
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US4761288A (en) * 1984-09-24 1988-08-02 Mezei Associates Limited Multiphase liposomal drug delivery system
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
DE3511981A1 (de) * 1985-04-02 1986-11-20 Fa. Fritz Genser, 8803 Rothenburg Verfahren zur vakuumrotationsverdampfung, sowie vorrichtung zur durchfuehrung des verfahrens
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Also Published As

Publication number Publication date
WO1990008535A1 (en) 1990-08-09
US4935171A (en) 1990-06-19
EP0457833A4 (en) 1992-03-11
EP0457833A1 (de) 1991-11-27
DE69022034D1 (de) 1995-10-05
JPH04504527A (ja) 1992-08-13
DE69022034T2 (de) 1996-04-11
ES2075894T3 (es) 1995-10-16
DK0457833T3 (da) 1995-09-25
EP0457833B1 (de) 1995-08-30
AU5103990A (en) 1990-08-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee