ATE127475T1 - Physiologisch wirksame peptide, die eine immunoregulierende aktivität besitzen. - Google Patents

Physiologisch wirksame peptide, die eine immunoregulierende aktivität besitzen.

Info

Publication number: ATE127475T1
Authority: AT; Austria
Prior art keywords: glu; val; asp; pro; peptides
Prior art date: 1990-07-12

Application number

AT91306332T

Other languages

English (en)

Inventor

Naoyoshi Suzuki

Original Assignee

Ajinomoto Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-12

Filing date

1991-07-12

Publication date

1995-09-15

1991-07-12 Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk

1995-09-15 Application granted granted Critical

1995-09-15 Publication of ATE127475T1 publication Critical patent/ATE127475T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
230000007365 immunoregulation Effects 0.000 title 1
125000003275 alpha amino acid group Chemical group 0.000 abstract 2
230000000844 anti-bacterial effect Effects 0.000 abstract 2
230000000840 anti-viral effect Effects 0.000 abstract 2
NAPNAGZWHQHZLG-ZLUOBGJFSA-N Asp-Asp-Ala Chemical compound C[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)N NAPNAGZWHQHZLG-ZLUOBGJFSA-N 0.000 abstract 1
IEFJWDNGDZAYNZ-BYPYZUCNSA-N Gly-Glu Chemical compound NCC(=O)N[C@H](C(O)=O)CCC(O)=O IEFJWDNGDZAYNZ-BYPYZUCNSA-N 0.000 abstract 1
108010002311 N-glycylglutamic acid Proteins 0.000 abstract 1
FUOGXAQMNJMBFG-WPRPVWTQSA-N Pro-Val-Gly Chemical compound OC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1 FUOGXAQMNJMBFG-WPRPVWTQSA-N 0.000 abstract 1
FHJQROWZEJFZPO-SRVKXCTJSA-N Pro-Val-Val Chemical compound CC(C)[C@@H](C(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1 FHJQROWZEJFZPO-SRVKXCTJSA-N 0.000 abstract 1
241000223997 Toxoplasma gondii Species 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
230000000884 anti-protozoa Effects 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
239000003443 antiviral agent Substances 0.000 abstract 1
230000004957 immunoregulator effect Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Tropical Medicine & Parasitology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Virology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AT91306332T 1990-07-12 1991-07-12 Physiologisch wirksame peptide, die eine immunoregulierende aktivität besitzen. ATE127475T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2182714A JPH0474197A (ja)	1990-07-12	1990-07-12	新規な免疫調整生理活性ペプチド

Publications (1)

Publication Number	Publication Date
ATE127475T1 true ATE127475T1 (de)	1995-09-15

Family

ID=16123154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91306332T ATE127475T1 (de)	1990-07-12	1991-07-12	Physiologisch wirksame peptide, die eine immunoregulierende aktivität besitzen.

Country Status (6)

Country	Link
US (1)	US5464819A (de)
EP (1)	EP0466498B1 (de)
JP (2)	JPH0474197A (de)
AT (1)	ATE127475T1 (de)
DE (1)	DE69112727T2 (de)
DK (1)	DK0466498T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6384022B1 (en)	1996-06-17	2002-05-07	Guilford Pharmaceuticals Inc.	Prodrugs of NAALAdase inhibitors
WO1998013046A1 (en)	1996-09-27	1998-04-02	Guilford Pharmaceuticals Inc.	Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals
US6395718B1 (en)	1998-07-06	2002-05-28	Guilford Pharmaceuticals Inc.	Pharmaceutical compositions and methods of inhibiting angiogenesis using naaladase inhibitors
US6228888B1 (en)	1999-07-01	2001-05-08	Guilford Pharmaceuticals Inc.	Methods for treating anxiety, anxiety disorders and memory impairment using naaladase inhibitors
US6759510B1 (en) *	2000-06-30	2004-07-06	Becton, Dickinson And Company	Peptides for use in culture media
US11174288B2 (en)	2016-12-06	2021-11-16	Northeastern University	Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ199752A (en) *	1981-02-27	1984-11-09	Otsuka Pharma Co Ltd	Glycoproteins and immunoactive compositions
US5066783A (en) *	1986-05-20	1991-11-19	Cohen Eric A	Antiviral peptides and means for treating herpes infections
JP2570670B2 (ja) *	1987-12-28	1997-01-08	味の素株式会社	トキソプラズマ増殖抑制剤

1990
- 1990-07-12 JP JP2182714A patent/JPH0474197A/ja active Pending
1991
- 1991-07-12 JP JP3198425A patent/JP2973621B2/ja not_active Expired - Fee Related
- 1991-07-12 DK DK91306332.7T patent/DK0466498T3/da active
- 1991-07-12 DE DE69112727T patent/DE69112727T2/de not_active Expired - Fee Related
- 1991-07-12 US US07/729,353 patent/US5464819A/en not_active Expired - Lifetime
- 1991-07-12 EP EP91306332A patent/EP0466498B1/de not_active Expired - Lifetime
- 1991-07-12 AT AT91306332T patent/ATE127475T1/de active

Also Published As

Publication number	Publication date
JPH05279383A (ja)	1993-10-26
JP2973621B2 (ja)	1999-11-08
DE69112727D1 (de)	1995-10-12
US5464819A (en)	1995-11-07
EP0466498B1 (de)	1995-09-06
JPH0474197A (ja)	1992-03-09
DE69112727T2 (de)	1996-05-02
DK0466498T3 (da)	1995-10-23
EP0466498A1 (de)	1992-01-15

Publication	Publication Date	Title
EP0528858A4 (en)	1993-04-28	Inhibitors of dipeptidyl-aminopeptidase type iv
ZA913213B (en)	1992-02-26	Nail enamels containing glyceryl,glycol or citrate esters
AU4425693A (en)	1994-02-10	Agents having a physiological cooling effect and active compounds which are suitable for these agents
GB8922026D0 (en)	1989-11-15	Novel anti-viral and cytotoxic agent
DK1025124T3 (da)	2008-10-06	Human interferon-alfa-analoge med lav toksicitet
DK0610743T3 (da)	1999-06-07	Immunsuppressive aminoethylen-peptider
AU9315398A (en)	1999-03-29	Chemokine peptides, variants, derivatives and analogs. their use in methods to inhibit or augment an inflammatory response
KR0180256B1 (en)	1999-04-01	Bpc peptides, their preparation and use
DE69302838D1 (de)	1996-07-04	Kosmetische und/oder pharmazeutische Zubereitungen und Verfahren zu ihrer Verwendung zum Schutz der Gewebe vor Kontakt mit Schwermetallen
NO921829L (no)	1992-07-09	Nytt polypeptid, samt anti-hiv-medikament fremstilt derav
CA2020663A1 (en)	1991-01-08	Substitution analogues of magainin peptides
ZA936692B (en)	1994-04-29	Physiologically active peptide composition
DE69112727D1 (de)	1995-10-12	Physiologisch wirksame Peptide, die eine immunoregulierende Aktivität besitzen.
IT8323059A0 (it)	1983-09-29	Tripeptide e tetrapeptide alchilamidi biologicamente attive, processi per la loro preparazione e composizioni farmaceutiche che le contengono.
KR960702754A (ko)	1996-05-23	생리적으로 활성인 펩티드를 함유하는 질내 투여 제제(vaginal preparation containing physiologically active peptide)
IT1164862B (it)	1987-04-15	Polipeptide dotato di attivita' di interferon, composizione che lo contiene e procedimento di preparazione
ATE90359T1 (de)	1993-06-15	Peptide.
RU94040865A (ru)	1996-08-10	Производные пептида и их терапевтически приемлемые соли, способ их получения, фармацевтическая и косметическая композиция с антивирусной активностью
ES2112921T3 (es)	1998-04-16	Peptidos y anticuerpos para el tratamiento de la artritis reumatoide.
EP0440688A4 (en)	1992-07-08	Cpf peptide compositions and uses
JPS53132539A (en)	1978-11-18	Protected amino acid or peptide having said protected amino acid residue
DE3869939D1 (de)	1992-05-14	Biologisch wirksame peptide.
ES2091571T3 (es)	1996-11-01	Nuevos derivados peptidicos activos en los procesos de adhesion celular, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
HU9303247D0 (en)	1994-03-28	Processfor producing 5-thia-1,4-diazabicyclo(4.2.0)octene-3,8-dioxo analogues of beta-lactame
DE3782199D1 (de)	1992-11-19	Biologisch aktive peptide tan-866.