ATE127475T1 - Physiologisch wirksame peptide, die eine immunoregulierende aktivität besitzen. - Google Patents

Physiologisch wirksame peptide, die eine immunoregulierende aktivität besitzen.

Info

Publication number: ATE127475T1
Authority: AT; Austria
Prior art keywords: glu; val; asp; pro; peptides
Prior art date: 1990-07-12

Application number

AT91306332T

Other languages

English (en)

Inventor

Naoyoshi Suzuki

Original Assignee

Ajinomoto Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-12

Filing date

1991-07-12

Publication date

1995-09-15

1991-07-12 Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk

1995-09-15 Application granted granted Critical

1995-09-15 Publication of ATE127475T1 publication Critical patent/ATE127475T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
230000007365 immunoregulation Effects 0.000 title 1
125000003275 alpha amino acid group Chemical group 0.000 abstract 2
230000000844 anti-bacterial effect Effects 0.000 abstract 2
230000000840 anti-viral effect Effects 0.000 abstract 2
NAPNAGZWHQHZLG-ZLUOBGJFSA-N Asp-Asp-Ala Chemical compound C[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)N NAPNAGZWHQHZLG-ZLUOBGJFSA-N 0.000 abstract 1
IEFJWDNGDZAYNZ-BYPYZUCNSA-N Gly-Glu Chemical compound NCC(=O)N[C@H](C(O)=O)CCC(O)=O IEFJWDNGDZAYNZ-BYPYZUCNSA-N 0.000 abstract 1
108010002311 N-glycylglutamic acid Proteins 0.000 abstract 1
FUOGXAQMNJMBFG-WPRPVWTQSA-N Pro-Val-Gly Chemical compound OC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1 FUOGXAQMNJMBFG-WPRPVWTQSA-N 0.000 abstract 1
FHJQROWZEJFZPO-SRVKXCTJSA-N Pro-Val-Val Chemical compound CC(C)[C@@H](C(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1 FHJQROWZEJFZPO-SRVKXCTJSA-N 0.000 abstract 1
241000223997 Toxoplasma gondii Species 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
230000000884 anti-protozoa Effects 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
239000003443 antiviral agent Substances 0.000 abstract 1
230000004957 immunoregulator effect Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Immunology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Virology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AT91306332T 1990-07-12 1991-07-12 Physiologisch wirksame peptide, die eine immunoregulierende aktivität besitzen. ATE127475T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2182714A JPH0474197A (ja)	1990-07-12	1990-07-12	新規な免疫調整生理活性ペプチド

Publications (1)

Publication Number	Publication Date
ATE127475T1 true ATE127475T1 (de)	1995-09-15

Family

ID=16123154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91306332T ATE127475T1 (de)	1990-07-12	1991-07-12	Physiologisch wirksame peptide, die eine immunoregulierende aktivität besitzen.

Country Status (6)

Country	Link
US (1)	US5464819A (de)
EP (1)	EP0466498B1 (de)
JP (2)	JPH0474197A (de)
AT (1)	ATE127475T1 (de)
DE (1)	DE69112727T2 (de)
DK (1)	DK0466498T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6384022B1 (en)	1996-06-17	2002-05-07	Guilford Pharmaceuticals Inc.	Prodrugs of NAALAdase inhibitors
CN1230889A (zh)	1996-09-27	1999-10-06	吉尔福特药业有限公司	NAALADase组合物和治疗谷氨酸异常及在动物中产生神经元活性的方法
US6395718B1 (en)	1998-07-06	2002-05-28	Guilford Pharmaceuticals Inc.	Pharmaceutical compositions and methods of inhibiting angiogenesis using naaladase inhibitors
US6228888B1 (en)	1999-07-01	2001-05-08	Guilford Pharmaceuticals Inc.	Methods for treating anxiety, anxiety disorders and memory impairment using naaladase inhibitors
US6759510B1 (en) *	2000-06-30	2004-07-06	Becton, Dickinson And Company	Peptides for use in culture media
US11174288B2 (en)	2016-12-06	2021-11-16	Northeastern University	Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ199752A (en) *	1981-02-27	1984-11-09	Otsuka Pharma Co Ltd	Glycoproteins and immunoactive compositions
US5066783A (en) *	1986-05-20	1991-11-19	Cohen Eric A	Antiviral peptides and means for treating herpes infections
JP2570670B2 (ja) *	1987-12-28	1997-01-08	味の素株式会社	トキソプラズマ増殖抑制剤

1990
- 1990-07-12 JP JP2182714A patent/JPH0474197A/ja active Pending
1991
- 1991-07-12 DK DK91306332.7T patent/DK0466498T3/da active
- 1991-07-12 JP JP3198425A patent/JP2973621B2/ja not_active Expired - Fee Related
- 1991-07-12 DE DE69112727T patent/DE69112727T2/de not_active Expired - Fee Related
- 1991-07-12 AT AT91306332T patent/ATE127475T1/de active
- 1991-07-12 US US07/729,353 patent/US5464819A/en not_active Expired - Lifetime
- 1991-07-12 EP EP91306332A patent/EP0466498B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69112727D1 (de)	1995-10-12
DK0466498T3 (da)	1995-10-23
US5464819A (en)	1995-11-07
JP2973621B2 (ja)	1999-11-08
DE69112727T2 (de)	1996-05-02
JPH0474197A (ja)	1992-03-09
EP0466498B1 (de)	1995-09-06
JPH05279383A (ja)	1993-10-26
EP0466498A1 (de)	1992-01-15

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