ATE127520T1 - Protein mit transaktivierender eigenschaft, dieses protein exprimierende vektoren, zellinien und seine verwendungen. - Google Patents

Protein mit transaktivierender eigenschaft, dieses protein exprimierende vektoren, zellinien und seine verwendungen.

Info

Publication number
ATE127520T1
ATE127520T1 AT90915880T AT90915880T ATE127520T1 AT E127520 T1 ATE127520 T1 AT E127520T1 AT 90915880 T AT90915880 T AT 90915880T AT 90915880 T AT90915880 T AT 90915880T AT E127520 T1 ATE127520 T1 AT E127520T1
Authority
AT
Austria
Prior art keywords
protein
transactivation
property
cell lines
vectors expressing
Prior art date
Application number
AT90915880T
Other languages
English (en)
Inventor
William A Haseltine
Ernest Terwilliger
Eric Cohen
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Application granted granted Critical
Publication of ATE127520T1 publication Critical patent/ATE127520T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16311Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT90915880T 1989-06-02 1990-06-01 Protein mit transaktivierender eigenschaft, dieses protein exprimierende vektoren, zellinien und seine verwendungen. ATE127520T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36102889A 1989-06-02 1989-06-02

Publications (1)

Publication Number Publication Date
ATE127520T1 true ATE127520T1 (de) 1995-09-15

Family

ID=23420358

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90915880T ATE127520T1 (de) 1989-06-02 1990-06-01 Protein mit transaktivierender eigenschaft, dieses protein exprimierende vektoren, zellinien und seine verwendungen.

Country Status (6)

Country Link
EP (1) EP0474797B1 (de)
JP (1) JPH04506605A (de)
AT (1) ATE127520T1 (de)
CA (1) CA2056452A1 (de)
DE (1) DE69022233T2 (de)
WO (1) WO1990015875A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874225A (en) 1993-02-19 1999-02-23 Trustees Of The University Of Pennsylvania Identification of compounds that modulate HIV-1 vpr protein activity
IL108707A (en) * 1993-02-19 1999-06-20 Weiner David B Pharmaceutical compositions and diagnostic kits comprising hiv protein vpr or proteins that bind to vpr
JPH09511395A (ja) * 1994-03-25 1997-11-18 バイオモレキュラー リサーチ インスティテュート リミティド HIV の Vpr及び Vpx蛋白質
US5861161A (en) 1994-09-07 1999-01-19 Universite De Montreal Chimeric proteins comprising a Vpr/Vpx virion incorporation domain for targeting into HIV-1 or HIV-2 virions
ATE408015T1 (de) * 1995-04-14 2008-09-15 Univ Alabama Res Found Transfer system basierend auf einem fusionsprotein und seine anwendungen.
US7622300B2 (en) 1998-06-03 2009-11-24 Kappes John C Trans-lentiviral vector particles and transduction of eukaryotic cells therewith
US6555342B1 (en) 1998-06-03 2003-04-29 Uab Research Foundation Fusion protein delivery system and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755457A (en) * 1985-02-05 1988-07-05 Robert Guroff Marjorie Method for detecting HTLV-III neutralizing antibodies in sera

Also Published As

Publication number Publication date
DE69022233D1 (de) 1995-10-12
DE69022233T2 (de) 1996-05-09
JPH04506605A (ja) 1992-11-19
EP0474797A4 (en) 1992-08-05
EP0474797A1 (de) 1992-03-18
EP0474797B1 (de) 1995-09-06
CA2056452A1 (en) 1990-12-03
WO1990015875A1 (en) 1990-12-27

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties