ATE76878T1 - Solubilisierung von protein-aggregaten. - Google Patents

Solubilisierung von protein-aggregaten.

Info

Publication number
ATE76878T1
ATE76878T1 AT86309603T AT86309603T ATE76878T1 AT E76878 T1 ATE76878 T1 AT E76878T1 AT 86309603 T AT86309603 T AT 86309603T AT 86309603 T AT86309603 T AT 86309603T AT E76878 T1 ATE76878 T1 AT E76878T1
Authority
AT
Austria
Prior art keywords
protein
solubilization
source
cationic surfactant
solubilisation
Prior art date
Application number
AT86309603T
Other languages
English (en)
Inventor
Joseph John Patroni
Malcolm Roy Brandon
Original Assignee
Fidelity Food Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidelity Food Tech filed Critical Fidelity Food Tech
Application granted granted Critical
Publication of ATE76878T1 publication Critical patent/ATE76878T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT86309603T 1985-12-11 1986-12-10 Solubilisierung von protein-aggregaten. ATE76878T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPH381885 1985-12-11
EP86309603A EP0226448B1 (de) 1985-12-11 1986-12-10 Solubilisierung von Protein-Aggregaten

Publications (1)

Publication Number Publication Date
ATE76878T1 true ATE76878T1 (de) 1992-06-15

Family

ID=3771404

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86309603T ATE76878T1 (de) 1985-12-11 1986-12-10 Solubilisierung von protein-aggregaten.

Country Status (14)

Country Link
US (1) US4797474A (de)
EP (1) EP0226448B1 (de)
JP (1) JPH0660198B2 (de)
CN (1) CN86108729A (de)
AT (1) ATE76878T1 (de)
AU (1) AU597924B2 (de)
CA (1) CA1281849C (de)
DE (1) DE3685562T2 (de)
DK (1) DK171331B1 (de)
ES (1) ES2032194T3 (de)
GR (1) GR3004903T3 (de)
MY (1) MY101204A (de)
NO (1) NO864990L (de)
NZ (1) NZ218586A (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5037644A (en) * 1986-10-27 1991-08-06 Cetus Corporation Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
AU612133B2 (en) * 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
CA1305285C (en) * 1987-04-21 1992-07-14 Malcolm Roy Brandon Production of proteins in active forms
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
US5654176A (en) * 1987-05-28 1997-08-05 Amrad Corporation Limited Fusion proteins containing glutathione-s-transferase
EP0295859B1 (de) * 1987-06-15 1994-11-17 Southern Cross Biotech Pty.Ltd. Herstellung von Proteinen in aktiver Form
AU609824B2 (en) * 1987-06-15 1991-05-09 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
US5266205A (en) * 1988-02-04 1993-11-30 Battelle Memorial Institute Supercritical fluid reverse micelle separation
US5637566A (en) * 1988-08-24 1997-06-10 Southern Cross Biotech Pty. Ltd. Method of improving carcass quality by administering growth hormone
US5136027A (en) * 1989-05-02 1992-08-04 Abbott Laboratories Method for renaturing proteins in the presence of alkyl sulfate detergents
DE69122280T2 (de) * 1990-03-01 1997-04-24 Hewlett Packard Co Minimierung von Eluatbandbreiten in der Flüssigchromatographie
US5530100A (en) * 1990-05-07 1996-06-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Methods for purification of recombinantly produced proteins
EP0529201B1 (de) * 1991-08-26 1997-09-24 Hewlett-Packard Company Chromatographisches Verfahren mit micellarer Anreicherung in der Säule
US5252216A (en) * 1992-03-24 1993-10-12 Smithkline Beecham Corporation Protein purification
EP0920306A2 (de) 1996-07-12 1999-06-09 Leukosite, Inc. Chemokinrezeptor antagoniste und verfahren zu deren herstellung
ZA9711733B (en) * 1996-12-31 1998-07-01 Monsanto Co Method for solubilization and naturation of somatotropins
US20020052026A1 (en) 1997-10-08 2002-05-02 Steven M. Vicik Methods of refolding proteins
CA2338665C (en) 1998-08-06 2011-01-18 Mountain View Pharmaceuticals, Inc. Peg-urate oxidase conjugates and use thereof
EP1558748A4 (de) * 2002-11-01 2008-10-22 Promega Corp Zellysezusammensetzungen, verwendungsverfahren, vorrichtung und kit
DE10309691B4 (de) 2003-02-28 2018-10-04 Hans-Knöll-Institut für Naturstoff-Forschung e.V. Gewinnung von löslichen Proteinen aus der Biomasse rekombinanter Mikroorganismen
US8188224B2 (en) 2005-04-11 2012-05-29 Savient Pharmaceuticals, Inc. Variant forms of urate oxidase and use thereof
WO2008051178A2 (en) 2006-04-12 2008-05-02 Savient Pharmaceuticals, Inc. Purification of proteins with cationic surfactant
US7811800B2 (en) 2005-04-11 2010-10-12 Savient Pharmaceuticals, Inc. Variant form of urate oxidase and use thereof
TWI418564B (zh) * 2005-04-11 2013-12-11 Savient Pharmaceuticals Inc 利用陽離子界面活性劑之蛋白質純化
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
JP2008545665A (ja) * 2005-05-23 2008-12-18 ユニベルシテ ドゥ ジュネーブ 高体温による処置のための注入可能な超常磁性ナノ粒子および高体温インプラントを形成するための使用
US20100221747A1 (en) * 2005-12-14 2010-09-02 Denka Seiken Co., Ltd. Immunochromatography detection of multidrug-resistant staphylococcus and diagnostic kit
EP2074223A4 (de) * 2006-09-15 2010-03-10 Foldrx Pharmaceuticals Inc Testverfahren zum nachweis von proteinen im nativen zustand und zur identifizierung von die stabilität von proteinen im nativen zustand modulierenden verbindungen
US9706787B2 (en) * 2007-10-05 2017-07-18 Advance International Inc. Systems and methods for deriving protein powder
US8663725B2 (en) * 2007-10-05 2014-03-04 Advance International Inc. Method for deriving a high-protein powder/ omega 3 oil and double distilled water from any kind of fish or animal ( protein)
EP4635567A3 (de) 2009-06-25 2025-12-03 Horizon Therapeutics USA, Inc. Verfahren und kits zur prävention des infusionsreaktionsrisikos und antikörpervermittelter reaktionsverlust durch überwachung von serumharnsäure während der pegylierten harnasetherapie
KR102067445B1 (ko) * 2012-05-31 2020-01-17 에이전시 포 사이언스, 테크놀로지 앤드 리서치 양전하 유기 첨가물 처리에 의한 단백질-오염물 복합체 및 단백질 제제 내 응집체 레벨의 감소 방법
US9826757B2 (en) 2013-03-15 2017-11-28 Advance International Inc. Automated method and system for recovering protein powder meal, pure omega 3 oil and purified distilled water from animal tissue
JP6147340B2 (ja) * 2013-05-29 2017-06-14 Jsr株式会社 洗浄用組成物、タンパク質精製方法、及びタンパク質
JP2017506646A (ja) * 2014-02-27 2017-03-09 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ タンパク質調製物のクロマチン含有量をアルキルカチオン処理によって減少させる方法
CA2920789C (en) 2015-06-04 2021-05-18 Advance International, Inc. Improved methods and systems for recovering protein powder and natural omega-3 oil from animal tissue
US20200237881A1 (en) 2019-01-30 2020-07-30 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
CN110234340A (zh) 2016-11-11 2019-09-13 好利恩风湿病制药有限责任公司 泼尼松和尿酸酶分子的组合疗法及其用途
WO2019103106A1 (ja) * 2017-11-22 2019-05-31 学校法人東京薬科大学 凝集タンパク質の再生剤およびこれを用いた凝集タンパク質の再生方法
US12121566B2 (en) 2019-01-30 2024-10-22 Horizon Therapeutics Usa, Inc. Methods for treating gout
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2829089A1 (de) * 1977-07-13 1979-02-01 Sandoz Ag Subunit-vakzine
US4462940A (en) * 1982-09-23 1984-07-31 Cetus Corporation Process for the recovery of human β-interferon-like polypeptides
US4659568A (en) * 1985-02-27 1987-04-21 American Cyanamid Company Process for solubilization, purification and characterization of protein from insoluble protein aggregates or complexes and compositions of matter therefrom
US4656255A (en) * 1985-09-09 1987-04-07 International Minerals & Chemical Corp. Protein recovery
EP0317561B1 (de) * 1986-07-28 1991-01-30 AlliedSignal Inc. Sulfonierte benzotriazole und ihre verwendung in polyamiden

Also Published As

Publication number Publication date
NZ218586A (en) 1989-07-27
NO864990L (no) 1987-06-12
AU597924B2 (en) 1990-06-14
DE3685562T2 (de) 1992-12-24
ES2032194T3 (es) 1993-01-16
DK171331B1 (da) 1996-09-09
AU6687486A (en) 1987-06-18
DE3685562D1 (de) 1992-07-09
JPS62223192A (ja) 1987-10-01
EP0226448A2 (de) 1987-06-24
CA1281849C (en) 1991-03-19
EP0226448A3 (en) 1989-01-11
MY101204A (en) 1991-08-17
GR3004903T3 (de) 1993-04-28
DK592186A (da) 1987-06-12
CN86108729A (zh) 1987-10-21
US4797474A (en) 1989-01-10
JPH0660198B2 (ja) 1994-08-10
DK592186D0 (da) 1986-12-10
NO864990D0 (no) 1986-12-10
EP0226448B1 (de) 1992-06-03

Similar Documents

Publication Publication Date Title
ATE76878T1 (de) Solubilisierung von protein-aggregaten.
ATE63748T1 (de) Enzymwiderstandsfaehige immunomodulatorische peptide.
DE3786592D1 (de) Transformation von trichoderma.
KR900700592A (ko) 용해성 티-4 유도체
ATE110782T1 (de) Rekombinanter menschlicher endothelzellenwachstumsfaktor.
DE69534878D1 (de) Neuartige adenovirale vektoren, verpackungsszellinien, rekombinante adenoviren und verfahren
BR0010725A (pt) Expressão e exportação de proteìnas de interferon-alfa como proteìnas de fusão de fc
ATE114156T1 (de) Herstellung von proteinen in aktiver form.
ATE90384T1 (de) Rekombinante virusproteine begleitet von lymphadenopathischem syndrom und/oder ''acquired immune deficiency syndrome'' (aids).
BR9507678A (pt) Construção de dna vetor de expressão recombinante célula proceso para produzir uma enzima enzima preparação de enzima uso da enzima e cultura
LU90855I2 (en) Proteine 1 osteogenique recombinante humaine: bmp-7 et ses d-riv-s pharmaceutiquement acceptables
ATE140968T1 (de) Kultur des wachstumsfaktors der vaskularen endothelialzellen und dns, die dafür kodiert
ATE157701T1 (de) Schnelle, vielseitige und einfache methode zur expression von genen in eukaryotischen zellen
ATE177472T1 (de) Expression von makrophagen-induzierbaren proteinen (mips) in hefezellen
FI90436B (fi) Ihmisen gammainterferonin kaltaisesti vaikuttavien polypeptidien valmistus
HUT68379A (en) Method for modifying the cell, tissue or host tropism of a recombinant microorganism obtained this way and use thereof in medicine and veterinary medicine
EP0676413A3 (de) Interferon alpha/beta bindendes Protein, seine Herstellung und Anwendung.
Parker et al. Demethylation of the type I procollagen genes in transformed fibroblasts treated with 5-azacytidine
AU1948788A (en) Expression of immunologically active proteins of human b-lymphotropic virus
Iqbal Observatory 7925, South Africa
UA10281C2 (uk) Спосіб отримання речовини для лікування захворювань підшлункової залози
BR1100911A (pt) Vetor de expressão, célula hospedeira cultivada e processo para produzir polipeptìdeo de interferon de consenso do leucócito humano

Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time