ATE127683T1 - Stabile emulgierte tretinoin-cremeformulierungen. - Google Patents

Stabile emulgierte tretinoin-cremeformulierungen.

Info

Publication number: ATE127683T1
Authority: AT; Austria
Prior art keywords: tretinoin; cream formulations; stable emulsified; tretinoin cream; weight
Prior art date: 1989-07-13

Application number

AT90307656T

Other languages

English (en)

Inventor

Prakash Parab

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-13

Filing date

1990-07-12

Publication date

1995-09-15

1990-07-12 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1995-09-15 Application granted granted Critical

1995-09-15 Publication of ATE127683T1 publication Critical patent/ATE127683T1/de

Links

SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 title abstract 3
229960001727 tretinoin Drugs 0.000 title abstract 3
239000006071 cream Substances 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 abstract 2
GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 abstract 2
229960000541 cetyl alcohol Drugs 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
239000000839 emulsion Substances 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Dermatology (AREA)
Engineering & Computer Science (AREA)
Birds (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Oil, Petroleum & Natural Gas (AREA)
Gerontology & Geriatric Medicine (AREA)
Medicinal Preparation (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Compositions Of Macromolecular Compounds (AREA)

AT90307656T 1989-07-13 1990-07-12 Stabile emulgierte tretinoin-cremeformulierungen. ATE127683T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US37929489A	1989-07-13	1989-07-13
US45364089A	1989-12-20	1989-12-20

Publications (1)

Publication Number	Publication Date
ATE127683T1 true ATE127683T1 (de)	1995-09-15

Family

ID=27008559

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90307656T ATE127683T1 (de)	1989-07-13	1990-07-12	Stabile emulgierte tretinoin-cremeformulierungen.

Country Status (10)

Country	Link
EP (1)	EP0408370B1 (de)
JP (1)	JPH03128307A (de)
KR (1)	KR920007567B1 (de)
AT (1)	ATE127683T1 (de)
AU (1)	AU621763B2 (de)
CA (1)	CA2020877C (de)
DE (1)	DE69022314T2 (de)
FI (1)	FI903483A7 (de)
IE (1)	IE902550A1 (de)
PT (1)	PT94687A (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5559149A (en)	1990-01-29	1996-09-24	Johnson & Johnson Consumer Products, Inc.	Skin care compositions containing retinoids
RO115109B1 (ro) *	1993-07-01	1999-11-30	Yamanouchi Europ Bv	Compozitie stabila cu retinoid
US5420106A (en) *	1994-03-22	1995-05-30	Bristol-Myers Squibb Company	Method and composition having enhanced alpha-hydroxy acid skin permeation and retention
FR2717686B1 (fr) *	1994-03-22	1996-06-28	Fabre Pierre Cosmetique	Composition dermo-cosmétologique et procédé de préparation.
US6461622B2 (en) *	1994-09-07	2002-10-08	Johnson & Johnson Consumer Companies, Inc.	Topical compositions
US6068847A (en) *	1996-10-03	2000-05-30	Johnson & Johnson Consumer Products, Inc.	Cosmetic compositions
USH2043H1 (en) *	1997-05-23	2002-08-06	The Procter & Gamble Company	Skin care compositions
JP3634139B2 (ja) *	1998-02-10	2005-03-30	株式会社資生堂	水中油型乳化組成物
US6210693B1 (en) *	1998-02-10	2001-04-03	Shiseido Company, Ltd.	Oil-in-water type emulsified composition
US6531141B1 (en)	2000-03-07	2003-03-11	Ortho-Mcneil Pharmaceutical, Inc.	Oil-in-water emulsion containing tretinoin
FR2857266B1 (fr) *	2003-07-07	2007-09-21	Jean Noel Thorel	Composition a usage dermatologique et/ou cosmetique, comprenant a titre de principe actif au moins un antioxydant lipophile
FR2925313A1 (fr) *	2007-12-19	2009-06-26	Oreal	Utilisation cosmetique de proteines de type plakoglobine
EP2149364A1 (de) *	2008-07-24	2010-02-03	Rohm and Haas Company	Verfahren zur Minderung des Geruchs in Körperpflegeprodukten
CA2928962A1 (en) *	2013-10-28	2015-05-07	Astion Pharma A/S	Dermatological compositions
KR101736478B1 (ko)	2017-01-10	2017-05-29	(주)씨드그룹	여드름 치료에 효능이 있는 로션 제조방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL257621A (de) *	1959-11-23
US3966967A (en) *	1973-03-21	1976-06-29	The Regents Of The University Of California	Compositions and methods of treating psoriasis with vinyligs of desmethyl retinoic acid
US3906108A (en) *	1973-10-12	1975-09-16	Johnson & Johnson	Stabilized tretinoin cream emulsion
GB1466062A (en) *	1974-04-09	1977-03-02	Knight K	Cosmetic preparations
US4678663A (en) *	1984-02-06	1987-07-07	Nuetrogena Corporation	Hydroquinone composition having enhanced bio-availability and percutaneous adsorption
EP0350438B1 (de) *	1988-06-13	1992-09-09	HERZOG, Paul	Mittel zur kosmetischen oder pharmazeutischen Verwendung
GB8821129D0 (en) *	1988-09-09	1988-10-12	Unilever Plc	Cosmetic composition

1990
- 1990-07-10 FI FI903483A patent/FI903483A7/fi not_active Application Discontinuation
- 1990-07-11 CA CA002020877A patent/CA2020877C/en not_active Expired - Fee Related
- 1990-07-12 PT PT94687A patent/PT94687A/pt not_active Application Discontinuation
- 1990-07-12 AT AT90307656T patent/ATE127683T1/de active
- 1990-07-12 DE DE69022314T patent/DE69022314T2/de not_active Expired - Fee Related
- 1990-07-12 EP EP90307656A patent/EP0408370B1/de not_active Expired - Lifetime
- 1990-07-12 KR KR1019900010586A patent/KR920007567B1/ko not_active Expired
- 1990-07-12 AU AU58959/90A patent/AU621763B2/en not_active Ceased
- 1990-07-12 IE IE255090A patent/IE902550A1/en unknown
- 1990-07-12 JP JP2185146A patent/JPH03128307A/ja active Pending

Also Published As

Publication number	Publication date
DE69022314T2 (de)	1996-03-14
KR910002435A (ko)	1991-02-25
KR920007567B1 (ko)	1992-09-07
DE69022314D1 (de)	1995-10-19
EP0408370B1 (de)	1995-09-13
FI903483A0 (fi)	1990-07-10
EP0408370A2 (de)	1991-01-16
AU5895990A (en)	1991-01-17
AU621763B2 (en)	1992-03-19
CA2020877A1 (en)	1991-01-14
IE902550A1 (en)	1991-02-27
JPH03128307A (ja)	1991-05-31
PT94687A (pt)	1991-03-20
EP0408370A3 (de)	1991-03-13
CA2020877C (en)	1995-04-25
FI903483A7 (fi)	1991-01-14

Publication	Publication Date	Title
AU621763B2 (en)	1992-03-19	Stable tretinoin emulsified cream formulations
FI891592A0 (fi)	1989-04-03	Hudvaordskomposition och foerfarande foer dess framstaellning.
US4613592A (en)	1986-09-23	Skin treatment composition
ATE107160T1 (de)	1994-07-15	Kosmetisches präparat.
US4772592A (en)	1988-09-20	Skin treatment composition
DK0631772T3 (da)	1999-12-06	Retinoidholdig sammensætning
DK0535734T3 (da)	1999-08-09	Langtidsvirkende injicerbare formuleringer indeholdende hydrogeneret castorolie
ATE98868T1 (de)	1994-01-15	Topisch kosmetisch anzuwendende depolymerisierte nukleinsaeuren enthaltende arzneizubereitungen.
ATE51343T1 (de)	1990-04-15	Abwaschbare topische zubereitung zur therapie der psoriasis.
EP0293766A3 (de)	1989-09-20	Emulsionen
AU629445B2 (en)	1992-10-01	Improvements in or relating to topical compositions containing 1 alpha 25-dihydroxycholecalciferol
NO892495D0 (no)	1989-06-15	Fremgangsmaate for fremstilling av farmasoeytiske preparat.
JPS55133305A (en)	1980-10-17	Perfume controller
IT8521528A0 (it)	1985-07-11	Composizioni farmaceutiche e cosmetiche contenenti come ingrediente attivo diidrossi-1,8fenil-10 antrone-9, e procedimentodi preparazione dell'ingrediente attivo.
IT8620703A0 (it)	1986-06-06	Derivati dell'acido 4-fenil 4-osso 2-butenoico, loro procedimento di preparazione e loro impiego come prodotti medicinali.
EP0685230A4 (de)	1996-01-24	Stabile dermatologische zubereitungen, die mycohenolsäure enthalten.
EP0359196A3 (de)	1991-02-13	Kosmetische Formulierung für die Hautpflege
EP0826371A4 (de)	2000-11-15	Emedastin enthaltende äusserlich anzuwendende zubereitung
KR927003530A (ko)	1992-12-18	이온삼투요법용 제약 제제의 제조에 있어서의 국소 마취제의 용도
IT1225467B (it)	1990-11-14	Composizioni pesticide e procedimento per la preparazione dell'ingrediente attivo.