ATE127779T1 - Verfahren zur herstellung von sertralin. - Google Patents

Verfahren zur herstellung von sertralin.

Info

Publication number: ATE127779T1
Authority: AT; Austria
Prior art keywords: pct; date jan; sec; compound; formula
Prior art date: 1991-07-11

Application number

AT92914143T

Other languages

English (en)

Inventor

Michael Trevelyan Williams

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-11

Filing date

1992-07-03

Publication date

1995-09-15

1992-07-03 Application filed by Pfizer filed Critical Pfizer

1995-09-15 Application granted granted Critical

1995-09-15 Publication of ATE127779T1 publication Critical patent/ATE127779T1/de

Links

229960002073 sertraline Drugs 0.000 title abstract 2
VGKDLMBJGBXTGI-SJCJKPOMSA-N sertraline Chemical compound C1([C@@H]2CC[C@@H](C3=CC=CC=C32)NC)=CC=C(Cl)C(Cl)=C1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/14—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Epoxy Compounds (AREA)

AT92914143T 1991-07-11 1992-07-03 Verfahren zur herstellung von sertralin. ATE127779T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB919114947A GB9114947D0 (en)	1991-07-11	1991-07-11	Process for preparing sertraline

Publications (1)

Publication Number	Publication Date
ATE127779T1 true ATE127779T1 (de)	1995-09-15

Family

ID=10698170

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92914143T ATE127779T1 (de)	1991-07-11	1992-07-03	Verfahren zur herstellung von sertralin.

Country Status (14)

Country	Link
US (1)	US5463126A (de)
EP (1)	EP0594666B1 (de)
JP (1)	JP2566374B2 (de)
AT (1)	ATE127779T1 (de)
CA (1)	CA2109817C (de)
DE (1)	DE69204840T2 (de)
DK (1)	DK0594666T3 (de)
ES (1)	ES2078749T3 (de)
FI (1)	FI112210B (de)
GB (1)	GB9114947D0 (de)
GR (1)	GR3017766T3 (de)
IE (1)	IE67822B1 (de)
PT (1)	PT100672B (de)
WO (1)	WO1993001162A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2777000B1 (fr) *	1998-04-01	2002-09-27	Catalys	Procede de preparation de la sertraline racemique
IL132500A0 (en)	1998-10-29	2001-03-19	Pfizer Prod Inc	Stereoselective microbial reduction of a racemic tetralone
WO2000032551A1 (en) *	1998-11-27	2000-06-08	Teva Pharmaceutical Industries Ltd.	Sertraline hydrochloride polymorphs
US6500987B1 (en) *	1998-11-27	2002-12-31	Teva Pharmaceutical Industries Ltd.	Sertraline hydrochloride polymorphs
RU2161851C1 (ru) *	1999-05-24	2001-01-10	Научно-производственное внедренческое предприятие "Феррогидродинамика"	Электрическая машина
US6495721B1 (en)	1999-08-09	2002-12-17	Teva Pharmaceutical Industries Ltd.	Sertraline hydrochloride Form II and methods for the preparation thereof
US20050119351A1 (en) *	1999-10-29	2005-06-02	Van Der Schaaf Paul A.	Polymorphic forms of sertraline hydrochloride
TWI260315B (en) *	1999-10-29	2006-08-21	Ciba Sc Holding Ag	Polymorphic forms of sertraline hydrochloride
US7442838B2 (en) *	1999-10-29	2008-10-28	Ciba Specialty Chemicals Corp.	Polymorphic forms of sertraline hydrochloride
PT1248605E (pt) *	1999-12-21	2007-03-30	Teva Pharma	Novos polimorfos de cloridrato de sertralina, processos para a sua preparação, composições que os contêm e métodos para a sua utilização
KR20070002101A (ko) *	2000-03-14	2007-01-04	테바 파마슈티컬 인더스트리즈 리미티드	(+)-시스-세르트랄린의 신규한 제조 방법
US6720003B2 (en)	2001-02-16	2004-04-13	Andrx Corporation	Serotonin reuptake inhibitor formulations
WO2003093217A1 (en) *	2002-04-29	2003-11-13	Teva Pharmaceutical Industries Ltd.	Process for preparation of polymorphic form ii of sertraline hydrochloride, pharmaceutical formulations and methods of administration thereof
US20060014838A1 (en) *	2004-07-14	2006-01-19	Sudhakar Valluri	Process for converting trans-sertraline to cis-sertraline
KR20250034266A (ko) *	2023-09-01	2025-03-11	환인제약 주식회사	설트랄린 또는 이의 염을 포함하는 약학적 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4269870A (en) *	1974-05-13	1981-05-26	Cooper Industries, Inc.	Solder flux and method
US4071489A (en) *	1976-03-08	1978-01-31	Rohm And Haas Company	Coating compositions from dicyclopentenyl acrylate and/or methacrylate
JPS5592293A (en) *	1978-12-28	1980-07-12	Sanwa Kagaku Kogyo Kk	Solid flux for soldering
US4536518A (en) *	1979-11-01	1985-08-20	Pfizer Inc.	Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
JPS5910497A (ja) *	1982-07-12	1984-01-19	Hitachi Ltd	フラックス
JPH0773795B2 (ja) *	1985-07-02	1995-08-09	太陽インキ製造株式会社	はんだ付用水洗性フラツクス組成物
US4882339A (en) *	1987-07-10	1989-11-21	Ciba-Geigy Corporation	4-Amino-substituted 1,2-dihydroxynaphthalene derivatives useful in inhibiting 5-lipoxygenase activity in mammals
US5071875A (en) *	1989-09-25	1991-12-10	Northwestern University	Substituted 2-amidotetralins as melatonin agonists and antagonists

1991
- 1991-07-11 GB GB919114947A patent/GB9114947D0/en active Pending
1992
- 1992-07-03 WO PCT/EP1992/001497 patent/WO1993001162A1/en not_active Ceased
- 1992-07-03 ES ES92914143T patent/ES2078749T3/es not_active Expired - Lifetime
- 1992-07-03 AT AT92914143T patent/ATE127779T1/de not_active IP Right Cessation
- 1992-07-03 JP JP5501953A patent/JP2566374B2/ja not_active Expired - Fee Related
- 1992-07-03 DK DK92914143.0T patent/DK0594666T3/da active
- 1992-07-03 EP EP92914143A patent/EP0594666B1/de not_active Expired - Lifetime
- 1992-07-03 CA CA002109817A patent/CA2109817C/en not_active Expired - Fee Related
- 1992-07-03 DE DE69204840T patent/DE69204840T2/de not_active Expired - Fee Related
- 1992-07-03 US US08/178,272 patent/US5463126A/en not_active Expired - Fee Related
- 1992-07-09 PT PT100672A patent/PT100672B/pt not_active IP Right Cessation
- 1992-07-10 IE IE922248A patent/IE67822B1/en not_active IP Right Cessation
1994
- 1994-01-10 FI FI940106A patent/FI112210B/fi not_active IP Right Cessation
1995
- 1995-10-18 GR GR950402868T patent/GR3017766T3/el unknown

Also Published As

Publication number	Publication date
ES2078749T3 (es)	1995-12-16
DE69204840T2 (de)	1996-02-22
PT100672B (pt)	1999-06-30
WO1993001162A1 (en)	1993-01-21
GR3017766T3 (en)	1996-01-31
IE67822B1 (en)	1996-05-01
FI940106A0 (fi)	1994-01-10
FI112210B (fi)	2003-11-14
PT100672A (pt)	1993-09-30
FI940106L (fi)	1994-01-10
JPH06509080A (ja)	1994-10-13
GB9114947D0 (en)	1991-08-28
US5463126A (en)	1995-10-31
DK0594666T3 (da)	1995-11-13
JP2566374B2 (ja)	1996-12-25
CA2109817C (en)	1999-08-31
EP0594666A1 (de)	1994-05-04
EP0594666B1 (de)	1995-09-13
IE922248A1 (en)	1993-01-13
DE69204840D1 (de)	1995-10-19

Similar Documents

Publication	Publication Date	Title
ATE132848T1 (de)	1996-01-15	Verfahren zur herstellung von sertralin- zwischenprodukten
ATE127779T1 (de)	1995-09-15	Verfahren zur herstellung von sertralin.
DE59108707D1 (de)	1997-06-26	Verfahren zur Herstellung von Oxetanonen
ATE109456T1 (de)	1994-08-15	Verfahren zur stereoselektiven herstellung von phenylisoserinderivaten.
FI941644A0 (fi)	1994-04-08	Sieniä vastustavat triatsoliyhdisteet
BR9509970A (pt)	1997-11-25	Composto
HU9501585D0 (en)	1995-08-28	Azoxycyanobenzene-derivatives, process for their preparation, fungicidal compositions containing them
ATE236139T1 (de)	2003-04-15	Verfahren zur herstellung von 2-chlor-5- chlomethyl-thiazol-derivaten
BR9507168A (pt)	1997-09-02	Composto e processo para a preparação do mesmo
DE59010545D1 (de)	1996-11-28	Phosphinesterhaltige N-Acyl-2-aminosäureamide, Verfahren zu ihrer Herstellung und N-Acyl-2-aminosäurenitrile als Vorprodukte
MX9102347A (es)	1992-06-01	Composicion nematicida que contiene el compuesto 2r, 5r-dihidroximetil-3r,4r-dihidroxipirrolidina.
PT100682A (pt)	1993-08-31	Agentes anti-helminticos derivados de benzimidazole e processo para a sua preparacao
DE3887102D1 (de)	1994-02-24	Substituierte Derivate von 20,21-Dinoreburnamenin, Verfahren zur Herstellung und so hergestellte Zwischenprodukte, ihre Verwendung als Arzneimittel und diese enthaltende pharmazeutische Zusammenstellungen.
DE69326767D1 (de)	1999-11-18	Verfahren und zwischenprodukte zur herstellung von bis-aza-bicyclischen anxiolytica
DE69406451D1 (de)	1997-11-27	Verfahren zur herstellung von n-carbonylarylimine als zwischenprodukte in der synthese von therapeutisch aktiven taxol-derivaten
ATE173259T1 (de)	1998-11-15	Verfahren zur herstellung von indolizinderivaten
DE69232406D1 (de)	2002-03-21	Verfahren zur Herstellung von Fluoro-Chinolin-3-Carbonsäurederivate
BR9509752A (pt)	1998-06-16	Composto e processo para preparar um composto
ATE185793T1 (de)	1999-11-15	Verfahren zur herstellung von isomerengemischen aus o-phenoxyalkylhydroxylaminen oder o- phenoxyalkyloximen
ATE175199T1 (de)	1999-01-15	Verfahren zur herstellung von 2-substituierten 5- chlorimidazol-4-carbaldehyden
ATE147744T1 (de)	1997-02-15	Verfahren zur herstellung von sulfonylpristinamycin iib
ATE135350T1 (de)	1996-03-15	Verfahren zur herstellung von 2-amino-7- nitrobenzothiazolen
DE69310369D1 (de)	1997-06-05	Verfahren zur herstellung von 3,3-diarylacrylsäureamiden
DE69620244D1 (de)	2002-05-02	Verfahren zur herstellung von prostaglandin e1
ES8605472A1 (es)	1986-03-16	Procedimiento para la preparacion de derivados de 1-(n-(a- amino-a-metilacetil)-aminofenil)-2-amino-propanona

Legal Events

Date	Code	Title	Description
2008-04-15	REN	Ceased due to non-payment of the annual fee