ATE128234T1 - Reagenzien zum ionenfangen und verfahren zur verrichtung von bindungsmessungen. - Google Patents

Reagenzien zum ionenfangen und verfahren zur verrichtung von bindungsmessungen.

Info

Publication number
ATE128234T1
ATE128234T1 AT89114103T AT89114103T ATE128234T1 AT E128234 T1 ATE128234 T1 AT E128234T1 AT 89114103 T AT89114103 T AT 89114103T AT 89114103 T AT89114103 T AT 89114103T AT E128234 T1 ATE128234 T1 AT E128234T1
Authority
AT
Austria
Prior art keywords
capture reagents
binding measurements
ion capture
performing binding
specific binding
Prior art date
Application number
AT89114103T
Other languages
English (en)
Inventor
Robert G Hiltibran
Stephen Denham Stroupe
Yi-Her Jou
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE128234T1 publication Critical patent/ATE128234T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57565—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen [CEA]

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT89114103T 1989-07-07 1989-07-31 Reagenzien zum ionenfangen und verfahren zur verrichtung von bindungsmessungen. ATE128234T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37502989A 1989-07-07 1989-07-07

Publications (1)

Publication Number Publication Date
ATE128234T1 true ATE128234T1 (de) 1995-10-15

Family

ID=23479199

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89114103T ATE128234T1 (de) 1989-07-07 1989-07-31 Reagenzien zum ionenfangen und verfahren zur verrichtung von bindungsmessungen.

Country Status (7)

Country Link
EP (2) EP0664451A1 (de)
JP (1) JPH07119764B2 (de)
KR (1) KR910003379A (de)
AT (1) ATE128234T1 (de)
CA (1) CA1341592C (de)
DE (1) DE68924345T2 (de)
ES (1) ES2080056T3 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459078A (en) * 1988-01-29 1995-10-17 Abbott Laboratories Methods and reagents for performing ion-capture digoxin assays
US5670381A (en) * 1988-01-29 1997-09-23 Abbott Laboratories Devices for performing ion-capture binding assays
SE462454B (sv) * 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
SE501013C2 (sv) * 1990-10-01 1994-10-17 Pharmacia Biosensor Ab Förfarande för förbättring av analys med bindning till fast fas
JP3267614B2 (ja) * 1991-05-30 2002-03-18 アボツト・ラボラトリーズ カルボキシメチルアミロースに結合させた結合メンバーを使用するイオン捕獲アッセイ
DE69223510T2 (de) * 1991-05-30 1998-06-18 Abbott Lab Verfahren und reagenzien zur ausführung von ioneneinfang-digoxin-assays
JPH06508212A (ja) * 1991-05-30 1994-09-14 アボツト・ラボラトリーズ イオン捕獲結合アッセイを実施する装置
ES2136090T3 (es) * 1991-05-30 1999-11-16 Abbott Lab Reactivos que contienen un inhibidor de fijacion no especifico para analisis de fijacion con captura de iones.
EP0586605B1 (de) * 1991-05-30 1998-08-05 Abbott Laboratories Reagenzien und verfahren zur ausführung eines zweistufigen ioneneinfang-assay
DK130991D0 (da) * 1991-07-04 1991-07-04 Immunodex K S Polymere konjugater
WO1993001498A1 (en) * 1991-07-04 1993-01-21 Immunodex K/S Water-soluble, polymer-based reagents and conjugates comprising moieties derived from divinyl sulfone
DE69332138T2 (de) * 1992-03-04 2003-03-27 Abbott Laboratories, Abbott Park Bestimmung von glykosyliertem hämoglobin durch dämpfung der fluoreszenz
SE9303272D0 (sv) * 1993-10-07 1993-10-07 Pharmacia Biosensor Ab Improvement in immunoassays
DE4408248A1 (de) * 1994-03-11 1995-09-14 Hoechst Ag Physiologisch verträgliche und physiologisch abbaubare Kohlenhydrat-Mimetika, ein Verfahren zur Herstellung und ihre Verwendung
AU1997895A (en) * 1994-03-15 1995-10-03 Abbott Laboratories Ion-capture reagents and methods for performing binding assays
CA2181109A1 (en) 1995-07-18 1997-01-19 Nobuko Imajo Polypeptide and process for measuring living body components using the same
US5854083A (en) * 1995-08-03 1998-12-29 Dade Behring Inc. Post synthesis chemical modification of particle reagents
US20050202499A1 (en) 1996-10-31 2005-09-15 Billing-Medel Patricia A. Reagents and methods useful for detecting diseases of the breast
US6846905B2 (en) 1997-08-15 2005-01-25 Abbott Laboratories Antigen constructs useful in the detection and differentiation of antibodies to HIV
SE9901306D0 (sv) * 1999-04-09 1999-04-09 Amersham Pharm Biotech Ab Improved TIRF chamber
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US20100168543A1 (en) 2003-08-01 2010-07-01 Dexcom, Inc. System and methods for processing analyte sensor data
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US7933639B2 (en) 2003-08-01 2011-04-26 Dexcom, Inc. System and methods for processing analyte sensor data
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US20080119703A1 (en) 2006-10-04 2008-05-22 Mark Brister Analyte sensor
US6931327B2 (en) 2003-08-01 2005-08-16 Dexcom, Inc. System and methods for processing analyte sensor data
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US8233959B2 (en) 2003-08-22 2012-07-31 Dexcom, Inc. Systems and methods for processing analyte sensor data
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8615282B2 (en) 2004-07-13 2013-12-24 Dexcom, Inc. Analyte sensor
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
DE602004029092D1 (de) 2003-12-05 2010-10-21 Dexcom Inc Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
EP2316331B1 (de) 2003-12-09 2016-06-29 Dexcom, Inc. Signalverarbeitung in einem durchgehenden Analytsensor
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US7946984B2 (en) 2004-07-13 2011-05-24 Dexcom, Inc. Transcutaneous analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US7776605B2 (en) 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
EP2097750A2 (de) 2006-10-26 2009-09-09 Abbott Laboratories Immunoassay aus analyten in proben mit endogenen antikörpern gegen analyte
US8562558B2 (en) 2007-06-08 2013-10-22 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
EP4159114B1 (de) 2007-10-09 2024-04-10 DexCom, Inc. Integriertes insulin-abgabesystem mit kontinuierlichem glucosesensor
EP2252196A4 (de) 2008-02-21 2013-05-15 Dexcom Inc Systeme und verfahren zur verarbeitung, übertragung und anzeige von sensordaten
EP4374790A3 (de) 2009-04-30 2024-07-31 DexCom, Inc. Mit kontinuierlichen sensordaten aus mehreren analysezeiträumen assoziierte leistungsberichte
US8652788B2 (en) 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US8835120B2 (en) 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US8183002B2 (en) 2009-12-03 2012-05-22 Abbott Laboratories Autoantibody enhanced immunoassays and kits
US20140170068A1 (en) 2011-03-11 2014-06-19 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
US20120265036A1 (en) 2011-04-15 2012-10-18 Dexcom, Inc. Advanced analyte sensor calibration and error detection
CN107102135A (zh) 2011-05-20 2017-08-29 阿波特日本有限公司 用于减少非特异性结合的免疫检验方法和试剂
CN117031013A (zh) * 2015-03-10 2023-11-10 西门子医疗保健诊断公司 固体载体上的官能团的定量
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
CN111246797B (zh) 2017-10-24 2025-09-09 德克斯康公司 预连接分析物传感器
CN116426510B (zh) * 2023-06-13 2023-09-22 北京沃森赛瑟生物技术有限公司 含修饰Xa因子的利伐沙班检测试剂盒及检测方法与应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145406A (en) * 1977-04-11 1979-03-20 Miles Laboratories, Inc. Specific binding - adsorbent assay method and test means
US4287300A (en) * 1979-07-26 1981-09-01 Syva Company Charge effects in enzyme immunoassays
JPS5719662A (en) * 1980-07-09 1982-02-01 Fuji Photo Film Co Ltd Preparation of microcapsule reagent for immune reaction
JPS59159827A (ja) * 1983-03-02 1984-09-10 Teijin Ltd 細胞毒性物質を結合した反応性重合体の製造法
FR2582656B1 (fr) * 1985-05-30 1987-07-31 Elf Aquitaine Procede de synthese de derives macromoleculaires du nicotinamide adenine
JPH0724768B2 (ja) * 1985-11-07 1995-03-22 味の素株式会社 ポリアミノ酸を基材としたアフイノフオア
ATE73690T1 (de) * 1985-12-20 1992-04-15 Syntex Inc Teilchentrennungsverfahren.
US4778751A (en) * 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
CA1304682C (en) * 1986-11-19 1992-07-07 Nobuo Monji Membrane affinity concentration immunoassay
AU609241B2 (en) * 1988-01-29 1991-04-26 Abbott Laboratories Ion-capture assays and devices

Also Published As

Publication number Publication date
DE68924345D1 (de) 1995-10-26
CA1341592C (en) 2009-04-14
EP0406473B1 (de) 1995-09-20
EP0664451A1 (de) 1995-07-26
ES2080056T3 (es) 1996-02-01
JPH07119764B2 (ja) 1995-12-20
KR910003379A (ko) 1991-02-27
EP0406473A1 (de) 1991-01-09
JPH0344399A (ja) 1991-02-26
DE68924345T2 (de) 1996-04-25

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee