ES2080056T3 - Reactivos para la captura de iones y metodos para la realizacion de ensayos. - Google Patents

Reactivos para la captura de iones y metodos para la realizacion de ensayos.

Info

Publication number
ES2080056T3
ES2080056T3 ES89114103T ES89114103T ES2080056T3 ES 2080056 T3 ES2080056 T3 ES 2080056T3 ES 89114103 T ES89114103 T ES 89114103T ES 89114103 T ES89114103 T ES 89114103T ES 2080056 T3 ES2080056 T3 ES 2080056T3
Authority
ES
Spain
Prior art keywords
capture
reagent
reagents
charged
analytical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89114103T
Other languages
English (en)
Inventor
Robert G Hiltibran
Stephen Denham Stroupe
Yi-Her Jou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2080056T3 publication Critical patent/ES2080056T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57565—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen [CEA]

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

ESTA INVENCION PRESENTA NUEVOS REACTIVOS, TECNICAS DE SEPARACION Y PROCEDIMIENTOS DE ENSAYO, LOS CUALES PERMITEN TANTO LA DETECCION COMO LA CAPTURA DE REACTIVOS QUE ESTAN EN SOLUCION PARA EVITAR PROBLEMAS DE INMUNOREACCIONES QUINETICAS RALENTIZADAS. EL PROCEDIMIENTO DE SEPARACION INCLUYE UNA CAPTURA DE REACTIVO SOLUBLE, QUE COMPRENDE UN MIEMBRO DE ENLACE ESPECIFICO UNIDO A UNA SUBSTANCIA CARGADA, Y UNA FASE SOLIDA INSOLUBLE QUE ESTA OPUESTAMENTE CARGADA CON RESPECTO AL REACTIVO DE CAPTURA. UNA MUESTRA DE ENSAYO SUSCEPTIBLE DE CONTENER EL ANALITICO DE INTERES SE MEZCLA CON EL REACTIVO DE CAPTURA PARA FORMAR UN COMPLEJO ANALITICO/REACTIVO DE CAPTURA CARGADO. LA MEZCLA DE REACCION SE PONE EN CONTACTO CON LA FASE SOLIDA OPUESTAMENTE CARGADA PARA ATRAER, RETENER, Y SEPARAR EL COMPLEJO ANALITICO/REACTIVO DE CAPTURA DE LA MEZCLA DE REACCION. CON UN DETECTOR DE REACTIVO ADECUADO, P.EJ. UNA SEGUNDA SUBSTANCIA ESPECIFICA DE ENLACE, LA CUAL ESTA CONJUGADA CON UNA ETIQUETA CAPAZ DE PRODUCIR UNA SEÑAL DETECTABLE SE PUEDEN REALIZAR TANTO LA COMBINACION COMO UN ENSAYO COMPETITIVO.
ES89114103T 1989-07-07 1989-07-31 Reactivos para la captura de iones y metodos para la realizacion de ensayos. Expired - Lifetime ES2080056T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37502989A 1989-07-07 1989-07-07

Publications (1)

Publication Number Publication Date
ES2080056T3 true ES2080056T3 (es) 1996-02-01

Family

ID=23479199

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89114103T Expired - Lifetime ES2080056T3 (es) 1989-07-07 1989-07-31 Reactivos para la captura de iones y metodos para la realizacion de ensayos.

Country Status (7)

Country Link
EP (2) EP0406473B1 (es)
JP (1) JPH07119764B2 (es)
KR (1) KR910003379A (es)
AT (1) ATE128234T1 (es)
CA (1) CA1341592C (es)
DE (1) DE68924345T2 (es)
ES (1) ES2080056T3 (es)

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US5459078A (en) * 1988-01-29 1995-10-17 Abbott Laboratories Methods and reagents for performing ion-capture digoxin assays
US5670381A (en) * 1988-01-29 1997-09-23 Abbott Laboratories Devices for performing ion-capture binding assays
SE462454B (sv) * 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
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CA2109925C (en) * 1991-05-30 2004-11-09 Janina Adamczyk Reagents and methods for performing two-step ion-capture binding assays
ATE181965T1 (de) * 1991-05-30 1999-07-15 Abbott Lab Reagenzien, die einen nichtspezifischen bindungshemmer in einem ioneneinfang-assay enthalten
EP0641442B1 (en) * 1991-05-30 1997-12-17 Abbott Laboratories Devices for performing ion-capture binding assays
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AU1997895A (en) * 1994-03-15 1995-10-03 Abbott Laboratories Ion-capture reagents and methods for performing binding assays
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US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US7519408B2 (en) 2003-11-19 2009-04-14 Dexcom, Inc. Integrated receiver for continuous analyte sensor
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US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US7778680B2 (en) 2003-08-01 2010-08-17 Dexcom, Inc. System and methods for processing analyte sensor data
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US20100168542A1 (en) 2003-08-01 2010-07-01 Dexcom, Inc. System and methods for processing analyte sensor data
US7925321B2 (en) 2003-08-01 2011-04-12 Dexcom, Inc. System and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US8233959B2 (en) 2003-08-22 2012-07-31 Dexcom, Inc. Systems and methods for processing analyte sensor data
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8774886B2 (en) 2006-10-04 2014-07-08 Dexcom, Inc. Analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
EP2239567B1 (en) 2003-12-05 2015-09-02 DexCom, Inc. Calibration techniques for a continuous analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP2316331B1 (en) 2003-12-09 2016-06-29 Dexcom, Inc. Signal processing for continuous analyte sensor
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US8989833B2 (en) 2004-07-13 2015-03-24 Dexcom, Inc. Transcutaneous analyte sensor
US7857760B2 (en) 2004-07-13 2010-12-28 Dexcom, Inc. Analyte sensor
CA2667012A1 (en) 2006-10-26 2008-05-02 Abbott Laboratories Immunoassay of analytes in samples containing endogenous anti-analyte antibodies
US7776605B2 (en) 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
US20080306434A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
EP2227132B1 (en) 2007-10-09 2023-03-08 DexCom, Inc. Integrated insulin delivery system with continuous glucose sensor
US8591455B2 (en) 2008-02-21 2013-11-26 Dexcom, Inc. Systems and methods for customizing delivery of sensor data
US20110004085A1 (en) 2009-04-30 2011-01-06 Dexcom, Inc. Performance reports associated with continuous sensor data from multiple analysis time periods
US8652788B2 (en) 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
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Also Published As

Publication number Publication date
DE68924345T2 (de) 1996-04-25
KR910003379A (ko) 1991-02-27
ATE128234T1 (de) 1995-10-15
EP0664451A1 (en) 1995-07-26
DE68924345D1 (de) 1995-10-26
CA1341592C (en) 2009-04-14
JPH07119764B2 (ja) 1995-12-20
JPH0344399A (ja) 1991-02-26
EP0406473B1 (en) 1995-09-20
EP0406473A1 (en) 1991-01-09

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