ES2080056T3 - Reactivos para la captura de iones y metodos para la realizacion de ensayos. - Google Patents
Reactivos para la captura de iones y metodos para la realizacion de ensayos.Info
- Publication number
- ES2080056T3 ES2080056T3 ES89114103T ES89114103T ES2080056T3 ES 2080056 T3 ES2080056 T3 ES 2080056T3 ES 89114103 T ES89114103 T ES 89114103T ES 89114103 T ES89114103 T ES 89114103T ES 2080056 T3 ES2080056 T3 ES 2080056T3
- Authority
- ES
- Spain
- Prior art keywords
- capture
- reagent
- reagents
- charged
- analytical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
- C08G69/10—Alpha-amino-carboxylic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57565—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen [CEA]
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
ESTA INVENCION PRESENTA NUEVOS REACTIVOS, TECNICAS DE SEPARACION Y PROCEDIMIENTOS DE ENSAYO, LOS CUALES PERMITEN TANTO LA DETECCION COMO LA CAPTURA DE REACTIVOS QUE ESTAN EN SOLUCION PARA EVITAR PROBLEMAS DE INMUNOREACCIONES QUINETICAS RALENTIZADAS. EL PROCEDIMIENTO DE SEPARACION INCLUYE UNA CAPTURA DE REACTIVO SOLUBLE, QUE COMPRENDE UN MIEMBRO DE ENLACE ESPECIFICO UNIDO A UNA SUBSTANCIA CARGADA, Y UNA FASE SOLIDA INSOLUBLE QUE ESTA OPUESTAMENTE CARGADA CON RESPECTO AL REACTIVO DE CAPTURA. UNA MUESTRA DE ENSAYO SUSCEPTIBLE DE CONTENER EL ANALITICO DE INTERES SE MEZCLA CON EL REACTIVO DE CAPTURA PARA FORMAR UN COMPLEJO ANALITICO/REACTIVO DE CAPTURA CARGADO. LA MEZCLA DE REACCION SE PONE EN CONTACTO CON LA FASE SOLIDA OPUESTAMENTE CARGADA PARA ATRAER, RETENER, Y SEPARAR EL COMPLEJO ANALITICO/REACTIVO DE CAPTURA DE LA MEZCLA DE REACCION. CON UN DETECTOR DE REACTIVO ADECUADO, P.EJ. UNA SEGUNDA SUBSTANCIA ESPECIFICA DE ENLACE, LA CUAL ESTA CONJUGADA CON UNA ETIQUETA CAPAZ DE PRODUCIR UNA SEÑAL DETECTABLE SE PUEDEN REALIZAR TANTO LA COMBINACION COMO UN ENSAYO COMPETITIVO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37502989A | 1989-07-07 | 1989-07-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2080056T3 true ES2080056T3 (es) | 1996-02-01 |
Family
ID=23479199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89114103T Expired - Lifetime ES2080056T3 (es) | 1989-07-07 | 1989-07-31 | Reactivos para la captura de iones y metodos para la realizacion de ensayos. |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP0664451A1 (es) |
| JP (1) | JPH07119764B2 (es) |
| KR (1) | KR910003379A (es) |
| AT (1) | ATE128234T1 (es) |
| CA (1) | CA1341592C (es) |
| DE (1) | DE68924345T2 (es) |
| ES (1) | ES2080056T3 (es) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5459078A (en) * | 1988-01-29 | 1995-10-17 | Abbott Laboratories | Methods and reagents for performing ion-capture digoxin assays |
| US5670381A (en) * | 1988-01-29 | 1997-09-23 | Abbott Laboratories | Devices for performing ion-capture binding assays |
| SE462454B (sv) * | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| SE501013C2 (sv) * | 1990-10-01 | 1994-10-17 | Pharmacia Biosensor Ab | Förfarande för förbättring av analys med bindning till fast fas |
| JP3267614B2 (ja) * | 1991-05-30 | 2002-03-18 | アボツト・ラボラトリーズ | カルボキシメチルアミロースに結合させた結合メンバーを使用するイオン捕獲アッセイ |
| JP3267613B2 (ja) * | 1991-05-30 | 2002-03-18 | アボツト・ラボラトリーズ | イオン捕獲結合アッセイにおける非特異的結合遮断薬を含む試薬 |
| ES2112320T3 (es) * | 1991-05-30 | 1998-04-01 | Abbott Lab | Procedimientos y reactivos con captura de iones que permiten determinar el contenido en digoxina. |
| JPH06508211A (ja) * | 1991-05-30 | 1994-09-14 | アボツト・ラボラトリーズ | 2ステップイオン捕獲結合アッセイを実施するための試薬及び方法 |
| EP0641442B1 (en) * | 1991-05-30 | 1997-12-17 | Abbott Laboratories | Devices for performing ion-capture binding assays |
| DK130991D0 (da) * | 1991-07-04 | 1991-07-04 | Immunodex K S | Polymere konjugater |
| EP0594772B1 (en) * | 1991-07-04 | 1996-08-28 | Immunodex K/S | Water-soluble, polymer-based reagents and conjugates comprising moieties derived from divinyl sulfone |
| AU3737093A (en) * | 1992-03-04 | 1993-10-05 | Abbott Laboratories | Determination of glycated hemoglobin by fluorescence quenching |
| SE9303272D0 (sv) * | 1993-10-07 | 1993-10-07 | Pharmacia Biosensor Ab | Improvement in immunoassays |
| DE4408248A1 (de) * | 1994-03-11 | 1995-09-14 | Hoechst Ag | Physiologisch verträgliche und physiologisch abbaubare Kohlenhydrat-Mimetika, ein Verfahren zur Herstellung und ihre Verwendung |
| AU1997895A (en) * | 1994-03-15 | 1995-10-03 | Abbott Laboratories | Ion-capture reagents and methods for performing binding assays |
| CA2181109A1 (en) | 1995-07-18 | 1997-01-19 | Nobuko Imajo | Polypeptide and process for measuring living body components using the same |
| US5854083A (en) * | 1995-08-03 | 1998-12-29 | Dade Behring Inc. | Post synthesis chemical modification of particle reagents |
| US20050202499A1 (en) | 1996-10-31 | 2005-09-15 | Billing-Medel Patricia A. | Reagents and methods useful for detecting diseases of the breast |
| US6846905B2 (en) | 1997-08-15 | 2005-01-25 | Abbott Laboratories | Antigen constructs useful in the detection and differentiation of antibodies to HIV |
| SE9901306D0 (sv) * | 1999-04-09 | 1999-04-09 | Amersham Pharm Biotech Ab | Improved TIRF chamber |
| US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
| US9282925B2 (en) | 2002-02-12 | 2016-03-15 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US8010174B2 (en) | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US8423113B2 (en) | 2003-07-25 | 2013-04-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US8369919B2 (en) | 2003-08-01 | 2013-02-05 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
| US8160669B2 (en) | 2003-08-01 | 2012-04-17 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7774145B2 (en) | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8676287B2 (en) | 2003-08-01 | 2014-03-18 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor |
| US8761856B2 (en) | 2003-08-01 | 2014-06-24 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US8060173B2 (en) | 2003-08-01 | 2011-11-15 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US8285354B2 (en) | 2003-08-01 | 2012-10-09 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US20140121989A1 (en) | 2003-08-22 | 2014-05-01 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
| WO2005051170A2 (en) | 2003-11-19 | 2005-06-09 | Dexcom, Inc. | Integrated receiver for continuous analyte sensor |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US8364231B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
| US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US8532730B2 (en) | 2006-10-04 | 2013-09-10 | Dexcom, Inc. | Analyte sensor |
| ATE480761T1 (de) | 2003-12-05 | 2010-09-15 | Dexcom Inc | Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor |
| US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| EP2329763B1 (en) | 2003-12-09 | 2017-06-21 | DexCom, Inc. | Signal processing for continuous analyte sensor |
| US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| US8989833B2 (en) | 2004-07-13 | 2015-03-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8452368B2 (en) | 2004-07-13 | 2013-05-28 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8886272B2 (en) | 2004-07-13 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
| EP1991110B1 (en) | 2006-03-09 | 2018-11-07 | DexCom, Inc. | Systems and methods for processing analyte sensor data |
| US7776605B2 (en) | 2006-10-26 | 2010-08-17 | Abbott Laboratories | Assay for cardiac troponin autoantibodies |
| MX2009004460A (es) | 2006-10-26 | 2009-07-09 | Abbott Lab | Inmunoensayo de analitos en muestras que contienen anticuerpos anti-analito endogenos. |
| CA2688184A1 (en) | 2007-06-08 | 2008-12-18 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| EP4159114B1 (en) | 2007-10-09 | 2024-04-10 | DexCom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
| US8229535B2 (en) | 2008-02-21 | 2012-07-24 | Dexcom, Inc. | Systems and methods for blood glucose monitoring and alert delivery |
| US9149220B2 (en) | 2011-04-15 | 2015-10-06 | Dexcom, Inc. | Advanced analyte sensor calibration and error detection |
| EP3925533B1 (en) | 2009-04-30 | 2024-04-10 | DexCom, Inc. | Performance reports associated with continuous sensor data from multiple analysis time periods |
| US8652788B2 (en) | 2009-12-02 | 2014-02-18 | Abbott Laboratories | Assay for diagnosis of cardiac myocyte damage |
| US8835120B2 (en) | 2009-12-02 | 2014-09-16 | Abbott Laboratories | Assay for cardiac troponin-T (cTnT) |
| US8183002B2 (en) | 2009-12-03 | 2012-05-22 | Abbott Laboratories | Autoantibody enhanced immunoassays and kits |
| AU2012229156A1 (en) | 2011-03-11 | 2013-10-31 | Board Of Regents Of The University Of Nebraska | Biomarker for coronary artery disease |
| WO2012161288A1 (en) | 2011-05-20 | 2012-11-29 | Abbott Japan Co. Ltd. | Immunoassay methods and reagents for decreasing nonspecific binding |
| CN107430119A (zh) | 2015-03-10 | 2017-12-01 | 西门子医疗保健诊断公司 | 固体载体上的官能团的定量 |
| US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
| DK3928687T3 (da) | 2017-10-24 | 2024-09-30 | Dexcom Inc | Bærbar indretning med på forhånd forbundet analytsensor |
| CN116426510B (zh) * | 2023-06-13 | 2023-09-22 | 北京沃森赛瑟生物技术有限公司 | 含修饰Xa因子的利伐沙班检测试剂盒及检测方法与应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4145406A (en) * | 1977-04-11 | 1979-03-20 | Miles Laboratories, Inc. | Specific binding - adsorbent assay method and test means |
| US4287300A (en) * | 1979-07-26 | 1981-09-01 | Syva Company | Charge effects in enzyme immunoassays |
| JPS5719662A (en) * | 1980-07-09 | 1982-02-01 | Fuji Photo Film Co Ltd | Preparation of microcapsule reagent for immune reaction |
| JPS59159827A (ja) * | 1983-03-02 | 1984-09-10 | Teijin Ltd | 細胞毒性物質を結合した反応性重合体の製造法 |
| FR2582656B1 (fr) * | 1985-05-30 | 1987-07-31 | Elf Aquitaine | Procede de synthese de derives macromoleculaires du nicotinamide adenine |
| JPH0724768B2 (ja) * | 1985-11-07 | 1995-03-22 | 味の素株式会社 | ポリアミノ酸を基材としたアフイノフオア |
| AU601386B2 (en) * | 1985-12-20 | 1990-09-13 | Syntex (U.S.A.) Inc. | Particle separation method |
| US4778751A (en) * | 1986-05-12 | 1988-10-18 | Diagnostic Products Corporation | Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies |
| CA1304682C (en) * | 1986-11-19 | 1992-07-07 | Nobuo Monji | Membrane affinity concentration immunoassay |
| AU609241B2 (en) * | 1988-01-29 | 1991-04-26 | Abbott Laboratories | Ion-capture assays and devices |
-
1989
- 1989-07-14 CA CA000605772A patent/CA1341592C/en not_active Expired - Fee Related
- 1989-07-31 EP EP95102406A patent/EP0664451A1/en not_active Withdrawn
- 1989-07-31 EP EP89114103A patent/EP0406473B1/en not_active Expired - Lifetime
- 1989-07-31 ES ES89114103T patent/ES2080056T3/es not_active Expired - Lifetime
- 1989-07-31 AT AT89114103T patent/ATE128234T1/de not_active IP Right Cessation
- 1989-07-31 DE DE68924345T patent/DE68924345T2/de not_active Expired - Fee Related
- 1989-08-22 JP JP1215875A patent/JPH07119764B2/ja not_active Expired - Lifetime
- 1989-08-31 KR KR1019890012454A patent/KR910003379A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE68924345D1 (de) | 1995-10-26 |
| JPH0344399A (ja) | 1991-02-26 |
| JPH07119764B2 (ja) | 1995-12-20 |
| EP0664451A1 (en) | 1995-07-26 |
| KR910003379A (ko) | 1991-02-27 |
| DE68924345T2 (de) | 1996-04-25 |
| CA1341592C (en) | 2009-04-14 |
| EP0406473A1 (en) | 1991-01-09 |
| EP0406473B1 (en) | 1995-09-20 |
| ATE128234T1 (de) | 1995-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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