ATE128355T1 - Mischungen gegen husten/erkältungen mit gehalt an nichtsedierenden antihistaminika. - Google Patents
Mischungen gegen husten/erkältungen mit gehalt an nichtsedierenden antihistaminika.Info
- Publication number
- ATE128355T1 ATE128355T1 AT88904126T AT88904126T ATE128355T1 AT E128355 T1 ATE128355 T1 AT E128355T1 AT 88904126 T AT88904126 T AT 88904126T AT 88904126 T AT88904126 T AT 88904126T AT E128355 T1 ATE128355 T1 AT E128355T1
- Authority
- AT
- Austria
- Prior art keywords
- cough
- sedating
- cold
- anthistaminics
- mixtures containing
- Prior art date
Links
- 206010011224 Cough Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 229940124584 antitussives Drugs 0.000 abstract 2
- 206010019233 Headaches Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 206010037660 Pyrexia Diseases 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000003434 antitussive agent Substances 0.000 abstract 1
- 239000000850 decongestant Substances 0.000 abstract 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003172 expectorant agent Substances 0.000 abstract 1
- 230000003419 expectorant effect Effects 0.000 abstract 1
- 231100000869 headache Toxicity 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 206010025482 malaise Diseases 0.000 abstract 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/042,120 US4783465A (en) | 1984-04-09 | 1987-04-24 | Cough/cold mixtures comprising non-sedating antihistamine drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE128355T1 true ATE128355T1 (de) | 1995-10-15 |
Family
ID=21920155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88904126T ATE128355T1 (de) | 1987-04-24 | 1988-04-22 | Mischungen gegen husten/erkältungen mit gehalt an nichtsedierenden antihistaminika. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4783465A (de) |
| EP (1) | EP0311677B1 (de) |
| JP (1) | JPH01503539A (de) |
| AT (1) | ATE128355T1 (de) |
| AU (1) | AU610178B2 (de) |
| CA (1) | CA1327315C (de) |
| DE (1) | DE3854518T2 (de) |
| WO (1) | WO1988008302A1 (de) |
| ZA (1) | ZA882884B (de) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU643187B2 (en) * | 1984-04-09 | 1993-11-11 | Eugene M. Laska | Cough-cold mixtures comprising non-steroidal anti-inflammatory drugs |
| GB8707416D0 (en) * | 1987-03-27 | 1987-04-29 | Wellcome Found | Pharmaceutical formulations |
| GB8805268D0 (en) * | 1988-03-04 | 1988-04-07 | Glaxo Group Ltd | Medicaments |
| US4999226A (en) * | 1988-06-01 | 1991-03-12 | Merrell Dow Pharmaceuticals Inc. | Pharmaceutical compositions for piperidinoalkanol-ibuprofen combination |
| US4933172A (en) * | 1988-10-06 | 1990-06-12 | Warner-Lambert Co. | Method of and compositions for treating destructive periodontal disease |
| US4990535A (en) * | 1989-05-03 | 1991-02-05 | Schering Corporation | Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine |
| WO1992004022A1 (en) * | 1990-09-11 | 1992-03-19 | Richardson Vicks Inc. | Use of compositions containing 2-(6'-substituted-2'-naphthyl)-acetic acid derivatives for the treatment of respiratory disorders |
| WO1992005783A1 (en) * | 1990-09-28 | 1992-04-16 | Merck & Co., Inc. | Ibuprofen-antihistamine combinations |
| JPH06506198A (ja) * | 1991-03-04 | 1994-07-14 | ワーナー−ランバート・コンパニー | 種々な剤形の非ステロイド性抗炎症剤の新規な塩／イオン対 |
| FR2673842B1 (fr) * | 1991-03-13 | 1993-12-24 | Rhone Poulenc Rorer Sa | Nouvelles compositions liquides a base de derives de la piperidine substitues en 1,4. |
| US5164398A (en) * | 1991-04-01 | 1992-11-17 | Merck & Co., Inc. | Ibuprofen-antitussive combinations |
| AU1766292A (en) * | 1991-04-01 | 1992-11-02 | Mcneil-Ppc, Inc. | Ibuprofen-decongestant combinations |
| FR2684298B1 (fr) * | 1991-12-03 | 1994-03-11 | Rhone Poulenc Rorer Sa | Nouvelles compositions pharmaceutiques solides a base de derives de lapiperidine substitues en 1,4. |
| US5451401A (en) * | 1993-09-29 | 1995-09-19 | The Procter & Gamble Company | Diphosphonic acid esters as tartar control agents |
| ES2153863T3 (es) * | 1993-10-25 | 2001-03-16 | Merrell Pharma Inc | Composicion farmaceutica estable a base de terfenadina e ibuprofeno. |
| JP3779349B2 (ja) * | 1995-04-24 | 2006-05-24 | 興和株式会社 | ピペリジン誘導体 |
| US5906747A (en) * | 1995-11-13 | 1999-05-25 | Biosepra Inc. | Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates |
| US5648358A (en) * | 1996-03-05 | 1997-07-15 | Mitra; Sekhar | Compositions and methods for treating respiratory disorders |
| US6348216B1 (en) * | 1996-06-10 | 2002-02-19 | Knoll Pharmaceutical Company | Ibuprofen and narcotic analgesic compositions |
| US6361794B1 (en) | 1996-06-12 | 2002-03-26 | Basf Corporation | Method of making ibuprofen and narcotic analgesic composition |
| US5712310A (en) * | 1996-06-14 | 1998-01-27 | Alpharma Uspd, Inc. | Suspension of substantially water-insoluble drugs and methods of their manufacture |
| US6160020A (en) * | 1996-12-20 | 2000-12-12 | Mcneill-Ppc, Inc. | Alkali metal and alkaline-earth metal salts of acetaminophen |
| US6060060A (en) * | 1997-01-31 | 2000-05-09 | Bmb Patent Holding Corporation | Analgesic compositions from sweet peppers and methods of use thereof |
| GB2324242A (en) * | 1997-04-18 | 1998-10-21 | Atindra Nath Chakrabarty | Medicaments for treating viral infections |
| WO1998052566A1 (en) * | 1997-05-21 | 1998-11-26 | Warner-Lambert Company | Non-sedating acrivastine preparation |
| BR9812660A (pt) * | 1997-09-19 | 2000-08-22 | Procter & Gamble | Composições e métodos para tratar distúrbios respiratórios |
| IN188720B (de) * | 1997-11-06 | 2002-11-02 | Panacea Biotec Ltd | |
| US6384038B1 (en) * | 1998-04-14 | 2002-05-07 | Sepracor Inc. | Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants |
| US6194431B1 (en) | 1998-04-14 | 2001-02-27 | Paul D. Rubin | Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors |
| US6132758A (en) | 1998-06-01 | 2000-10-17 | Schering Corporation | Stabilized antihistamine syrup |
| US6086888A (en) * | 1998-12-22 | 2000-07-11 | Bmb Patent Holding Corporation | Analgesic compositions from sweet bell peppers and methods of use thereof |
| US6211246B1 (en) * | 1999-06-10 | 2001-04-03 | Mcneil-Ppc, Inc. | Rapidly absorbed liquid compositions |
| US6100274A (en) * | 1999-07-07 | 2000-08-08 | Schering Corporation | 8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions |
| US6114346A (en) * | 1999-10-22 | 2000-09-05 | Schering Corporation | Treating sleep disorders using desloratadine |
| WO2001045668A2 (en) * | 1999-12-20 | 2001-06-28 | Schering Corporation | Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine |
| AU2276801A (en) | 1999-12-20 | 2001-07-03 | Schering Corporation | Extended release oral dosage composition |
| US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
| CO5200779A1 (es) * | 2000-03-30 | 2002-09-27 | Schering Corp | Composiciones y metodos para tratar condiciones alergicas e inflamatorias con tos rgicas e inflamatorias con tos |
| US20030216423A1 (en) * | 2000-05-24 | 2003-11-20 | Sergio Ulloa | Stable liquid and solid formulations |
| AU2001264806A1 (en) * | 2000-05-25 | 2001-12-03 | Schering Corporation | Stable liquid and solid formulations |
| US6440983B1 (en) * | 2000-12-21 | 2002-08-27 | Mary Theresa Frank-Kollman | Compositions and methods for relieving headache symptoms in aspirin-sensitive headache sufferers |
| US7014867B2 (en) | 2001-06-28 | 2006-03-21 | Ucb Farchim Sa | Tablet comprising cetirizine and pseudoephedrine |
| US6863901B2 (en) | 2001-11-30 | 2005-03-08 | Collegium Pharmaceutical, Inc. | Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration |
| US6827946B2 (en) | 2001-12-05 | 2004-12-07 | Collegium Pharmaceutical, Inc. | Compositions containing both sedative and non-sedative antihistamines |
| CZ292874B6 (cs) * | 2002-01-30 | 2003-12-17 | Léčiva, A. S. | Farmaceutický prostředek k ošetření akutních bolestí |
| JP4614638B2 (ja) * | 2002-06-07 | 2011-01-19 | 第一三共株式会社 | 鎮痛剤組成物 |
| JP4614640B2 (ja) * | 2002-07-04 | 2011-01-19 | 第一三共株式会社 | 解熱剤組成物 |
| JP2010159299A (ja) * | 2002-07-04 | 2010-07-22 | Daiichi Sankyo Co Ltd | ロキソプロフェンとケトチフェンを含有する解熱剤組成物 |
| CL2003002653A1 (es) * | 2002-12-18 | 2005-04-22 | Wyeth Corp | Composicion farmaceutica que comprende (a) un antiinflamatorio no esteroidal (nsaid), preferentemente ibuprofeno, (b) un descongestionante, preferentemente pseudoefedrina y (c) un antihistaminico, preferentemente clorfeniramina; metodo para su prepar |
| US20040253311A1 (en) * | 2002-12-18 | 2004-12-16 | Roger Berlin | Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines |
| GB0312419D0 (en) * | 2003-05-30 | 2003-07-02 | Boots Healthcare Int Ltd | Use of a compound in the treatment of sleep disorders and the like, in providing refreshedness on waking and a method for the treatment of grogginess |
| EP2120945A1 (de) * | 2007-02-28 | 2009-11-25 | Collegium Pharmaceutical, Inc. | Antihistamin-kombination |
| ES2590604T3 (es) * | 2008-01-04 | 2016-11-22 | Schabar Research Associates Llc | Composición que comprende un analgésico y un antihistamínico |
| US8518439B2 (en) * | 2008-12-03 | 2013-08-27 | Novartis Ag | Liquid therapeutic composition |
| US10046052B2 (en) * | 2010-05-14 | 2018-08-14 | Bernard Silverman | Method and formulation for cold treatment in adults and children with increased safety |
| EP2985036A3 (de) | 2014-08-14 | 2016-03-09 | Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. | CYP2J2-Antagonisten zur Behandlung von Schmerzen |
| US11219629B2 (en) | 2019-10-17 | 2022-01-11 | Hooman M. MELAMED | Anesthetic pharmaceutical composition, system and method |
| US11324727B2 (en) | 2020-07-15 | 2022-05-10 | Schabar Research Associates, Llc | Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn |
| KR20230051164A (ko) | 2020-07-15 | 2023-04-17 | 샤바르 리서치 어소시에이츠 엘엘씨 | 급성 통증의 치료 및 속쓰림의 중증도 및/또는 위험의 감소를 위한 이부프로펜 및 파모티딘으로 구성된 단위 경구 투여 조성물 |
| US12514846B2 (en) | 2020-07-15 | 2026-01-06 | Schabar Research Associates Llc | Unit oral dose compositions composed of ibuprofen or a pharmaceutically acceptable salt thereof and famotidine or a pharmaceutically acceptable salt thereof for the treatment of acute pain and the reduction of the severity and/or risk of heartburn and/or upset stomach |
| WO2022119431A1 (es) | 2020-12-04 | 2022-06-09 | Laboratorios Silanes S.A. De C.V. | Composición farmacéutica de un analgésico y un antihistamínico para el tratamiento de enfermedades respiratorias |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522826A (en) * | 1984-02-08 | 1985-06-11 | Richardson-Vicks Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
| US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
| US4810502A (en) * | 1987-02-27 | 1989-03-07 | Alza Corporation | Pseudoephedrine brompheniramine therapy |
-
1987
- 1987-04-24 US US07/042,120 patent/US4783465A/en not_active Expired - Lifetime
-
1988
- 1988-04-22 CA CA000564793A patent/CA1327315C/en not_active Expired - Lifetime
- 1988-04-22 AT AT88904126T patent/ATE128355T1/de not_active IP Right Cessation
- 1988-04-22 WO PCT/US1988/001264 patent/WO1988008302A1/en not_active Ceased
- 1988-04-22 DE DE3854518T patent/DE3854518T2/de not_active Revoked
- 1988-04-22 JP JP63503899A patent/JPH01503539A/ja active Pending
- 1988-04-22 AU AU16873/88A patent/AU610178B2/en not_active Expired
- 1988-04-22 ZA ZA882884A patent/ZA882884B/xx unknown
- 1988-04-22 EP EP88904126A patent/EP0311677B1/de not_active Revoked
Also Published As
| Publication number | Publication date |
|---|---|
| AU610178B2 (en) | 1991-05-16 |
| EP0311677A1 (de) | 1989-04-19 |
| EP0311677B1 (de) | 1995-09-27 |
| CA1327315C (en) | 1994-03-01 |
| JPH01503539A (ja) | 1989-11-30 |
| DE3854518D1 (de) | 1995-11-02 |
| WO1988008302A1 (en) | 1988-11-03 |
| ZA882884B (en) | 1988-10-27 |
| DE3854518T2 (de) | 1996-02-22 |
| US4783465A (en) | 1988-11-08 |
| AU1687388A (en) | 1988-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| RZN | Patent revoked |