ATE128357T1 - Ophthalmikum. - Google Patents

Ophthalmikum.

Info

Publication number: ATE128357T1
Authority: AT; Austria
Prior art keywords: cyclic; gmp; analog; monophosphate; ophthalmic
Prior art date: 1989-06-29

Application number

AT90870103T

Other languages

English (en)

Inventor

Bernard Becker

Original Assignee

Univ Washington

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-29

Filing date

1990-06-26

Publication date

1995-10-15

1990-06-26 Application filed by Univ Washington filed Critical Univ Washington

1995-10-15 Application granted granted Critical

1995-10-15 Publication of ATE128357T1 publication Critical patent/ATE128357T1/de

Links

ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 abstract 3
ZOOGRGPOEVQQDX-UHFFFAOYSA-N cyclic GMP Natural products O1C2COP(O)(=O)OC2C(O)C1N1C=NC2=C1NC(N)=NC2=O ZOOGRGPOEVQQDX-UHFFFAOYSA-N 0.000 abstract 2
ASUCSHXLTWZYBA-UMMCILCDSA-N 8-Bromoguanosine Chemical compound C1=2NC(N)=NC(=O)C=2N=C(Br)N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O ASUCSHXLTWZYBA-UMMCILCDSA-N 0.000 abstract 1
102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
230000003247 decreasing effect Effects 0.000 abstract 1
RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 abstract 1
235000013928 guanylic acid Nutrition 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
230000004410 intraocular pressure Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Ophthalmology & Optometry (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

AT90870103T 1989-06-29 1990-06-26 Ophthalmikum. ATE128357T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US37372589A	1989-06-29	1989-06-29

Publications (1)

Publication Number	Publication Date
ATE128357T1 true ATE128357T1 (de)	1995-10-15

Family

ID=23473611

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90870103T ATE128357T1 (de)	1989-06-29	1990-06-26	Ophthalmikum.

Country Status (8)

Country	Link
EP (1)	EP0406210B1 (de)
JP (1)	JPH0338526A (de)
AT (1)	ATE128357T1 (de)
CA (1)	CA2020085A1 (de)
DE (1)	DE69022638T2 (de)
DK (1)	DK0406210T3 (de)
ES (1)	ES2080137T3 (de)
GR (1)	GR3018267T3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT409967B (de)	2000-10-17	2002-12-27	Solutia Austria Gmbh	Zweikomponentensysteme auf basis von wasserlöslichen polyestern und verkappten isocyanaten zur formulierung von wasserverdünnbaren einbrennlacken

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4753945A (en) *	1986-02-19	1988-06-28	Eye Research Institute Of Retina Foundation	Stimulation of tear secretion with phosphodiesterase inhibitors
EP0583821B1 (de) *	1987-01-23	2000-03-29	The General Hospital Corporation	Hydralazin zur topischen Behandlung von Glaukom

1990
- 1990-06-26 ES ES90870103T patent/ES2080137T3/es not_active Expired - Lifetime
- 1990-06-26 DK DK90870103.0T patent/DK0406210T3/da active
- 1990-06-26 EP EP90870103A patent/EP0406210B1/de not_active Expired - Lifetime
- 1990-06-26 DE DE69022638T patent/DE69022638T2/de not_active Expired - Fee Related
- 1990-06-26 AT AT90870103T patent/ATE128357T1/de not_active IP Right Cessation
- 1990-06-28 JP JP2168629A patent/JPH0338526A/ja active Pending
- 1990-06-28 CA CA002020085A patent/CA2020085A1/en not_active Abandoned
1995
- 1995-11-30 GR GR950403384T patent/GR3018267T3/el unknown

Also Published As

Publication number	Publication date
EP0406210A2 (de)	1991-01-02
DK0406210T3 (da)	1995-12-04
ES2080137T3 (es)	1996-02-01
CA2020085A1 (en)	1990-12-30
JPH0338526A (ja)	1991-02-19
DE69022638D1 (de)	1995-11-02
EP0406210A3 (en)	1991-10-09
GR3018267T3 (en)	1996-02-29
DE69022638T2 (de)	1996-04-18
EP0406210B1 (de)	1995-09-27

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Legal Events

Date	Code	Title	Description
1996-04-15	UEP	Publication of translation of european patent specification
2001-03-15	REN	Ceased due to non-payment of the annual fee