ATE128973T1 - Verfahren zur herstellung von 3- benzoylbenzofuranderivaten. - Google Patents
Verfahren zur herstellung von 3- benzoylbenzofuranderivaten.Info
- Publication number
- ATE128973T1 ATE128973T1 AT90402967T AT90402967T ATE128973T1 AT E128973 T1 ATE128973 T1 AT E128973T1 AT 90402967 T AT90402967 T AT 90402967T AT 90402967 T AT90402967 T AT 90402967T AT E128973 T1 ATE128973 T1 AT E128973T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- benzoylbenzofurander
- image
- producing
- general formula
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 2
- CTSLXHKWHWQRSH-UHFFFAOYSA-N oxalyl chloride Chemical compound ClC(=O)C(Cl)=O CTSLXHKWHWQRSH-UHFFFAOYSA-N 0.000 abstract 2
- TWWAVGXQPVEBKZ-UHFFFAOYSA-N 1-benzofuran-3-yl(phenyl)methanone Chemical class C=1OC2=CC=CC=C2C=1C(=O)C1=CC=CC=C1 TWWAVGXQPVEBKZ-UHFFFAOYSA-N 0.000 abstract 1
- -1 3-benzoylbenzofuran compound Chemical class 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 150000001907 coumarones Chemical class 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000002989 phenols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8913851A FR2653431B1 (fr) | 1989-10-23 | 1989-10-23 | Procede de preparation de derives de benzoyl-3 benzofuranne. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE128973T1 true ATE128973T1 (de) | 1995-10-15 |
Family
ID=9386667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90402967T ATE128973T1 (de) | 1989-10-23 | 1990-10-22 | Verfahren zur herstellung von 3- benzoylbenzofuranderivaten. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5266711A (de) |
| EP (1) | EP0425359B1 (de) |
| JP (1) | JPH03169874A (de) |
| AT (1) | ATE128973T1 (de) |
| DE (1) | DE69022949T2 (de) |
| DK (1) | DK0425359T3 (de) |
| ES (1) | ES2078959T3 (de) |
| FR (1) | FR2653431B1 (de) |
| GR (1) | GR3018227T3 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999058519A1 (en) * | 1998-05-12 | 1999-11-18 | American Home Products Corporation | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| US6166069A (en) | 1998-05-12 | 2000-12-26 | American Home Products Corporation | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| US20030113330A1 (en) * | 1999-11-08 | 2003-06-19 | Uhal Bruce D. | Methods for treating pulmonary fibrosis |
| RU2186063C1 (ru) * | 2001-06-18 | 2002-07-27 | Федеральное государственное унитарное предприятие "Новокузнецкий научно-исследовательский химико-фармацевтический институт" | Способ получения 2-бутил-3-(3,5-дийод-4-оксибензоил)бензофурана |
| US7078541B2 (en) * | 2002-02-07 | 2006-07-18 | Galileo Pharmaceuticals, Inc. | Benzofuran derivatives |
| JP2005517014A (ja) * | 2002-02-07 | 2005-06-09 | ガリレオ ファーマシューティカルズ, インコーポレイテッド | 細胞保護性ベンゾフラン誘導体 |
| FR2864536B1 (fr) * | 2003-12-24 | 2006-03-17 | Clariant France Sa | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
| DE602006009940D1 (de) * | 2005-07-15 | 2009-12-03 | Aryx Therapeutics | Antiarrhythmische vorläuferverbindungen, syntheseverfahren und verwendungsverfahren |
| WO2012048058A2 (en) * | 2010-10-06 | 2012-04-12 | J-Pharma Co., Ltd. | Developing potent urate transporter inhibitors: compounds designed for their uricosuric action |
| EP2452938A1 (de) | 2010-11-12 | 2012-05-16 | LEK Pharmaceuticals d.d. | Verfahren zur Herstellung von 3-Aroyl-5-Aminobenzofuran-Derivaten |
| CN104262304A (zh) * | 2014-09-12 | 2015-01-07 | 杨俊� | 一种盐酸胺碘酮的合成方法 |
| CN104311516B (zh) * | 2014-09-16 | 2017-01-11 | 东北制药集团股份有限公司 | 一种苯溴马隆晶型b及其制备方法 |
| CN106065010B (zh) * | 2015-04-23 | 2019-01-01 | 镇江新元素医药科技有限公司 | 用于治疗或预防高尿酸血症或痛风的化合物 |
| CN106946822B (zh) * | 2017-03-21 | 2019-03-05 | 华中科技大学 | 一种2-丁基-3-(4-羟基苯甲酰基)苯并呋喃的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950355A (en) * | 1972-08-03 | 1976-04-13 | Mcneil Laboratories, Inc. | 5-chlorocarbonyl |
| US3947470A (en) * | 1974-06-20 | 1976-03-30 | Smithkline Corporation | Substituted benzofurans and benzothiophenes |
| US4780480A (en) * | 1983-07-14 | 1988-10-25 | Syntex (U.S.A.) Inc. | Aroyl benzofuran and benzothiophene acetic and propionic acids |
| FR2583754B1 (fr) * | 1985-06-25 | 1987-10-23 | Sanofi Sa | Complexes moleculaires formes d'un derive de benzofuranne et de chlorure d'aluminium, leur preparation et leur utilisation |
-
1989
- 1989-10-23 FR FR8913851A patent/FR2653431B1/fr not_active Expired - Fee Related
-
1990
- 1990-10-16 US US07/597,684 patent/US5266711A/en not_active Expired - Fee Related
- 1990-10-22 ES ES90402967T patent/ES2078959T3/es not_active Expired - Lifetime
- 1990-10-22 DE DE69022949T patent/DE69022949T2/de not_active Expired - Fee Related
- 1990-10-22 JP JP2285702A patent/JPH03169874A/ja active Pending
- 1990-10-22 EP EP90402967A patent/EP0425359B1/de not_active Expired - Lifetime
- 1990-10-22 AT AT90402967T patent/ATE128973T1/de not_active IP Right Cessation
- 1990-10-22 DK DK90402967.5T patent/DK0425359T3/da active
-
1995
- 1995-11-29 GR GR950403346T patent/GR3018227T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2078959T3 (es) | 1996-01-01 |
| DE69022949T2 (de) | 1996-05-15 |
| US5266711A (en) | 1993-11-30 |
| FR2653431A1 (fr) | 1991-04-26 |
| GR3018227T3 (en) | 1996-02-29 |
| FR2653431B1 (fr) | 1994-05-27 |
| JPH03169874A (ja) | 1991-07-23 |
| EP0425359A1 (de) | 1991-05-02 |
| DK0425359T3 (da) | 1996-01-22 |
| DE69022949D1 (de) | 1995-11-16 |
| EP0425359B1 (de) | 1995-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |