ATE129074T1 - Methode zum screening von zellen oder anderen geformten körpern zur spezifizierung von populationen, die ausgewählte charakteristische eigenschaften exprimieren. - Google Patents

Methode zum screening von zellen oder anderen geformten körpern zur spezifizierung von populationen, die ausgewählte charakteristische eigenschaften exprimieren.

Info

Publication number
ATE129074T1
ATE129074T1 AT88903630T AT88903630T ATE129074T1 AT E129074 T1 ATE129074 T1 AT E129074T1 AT 88903630 T AT88903630 T AT 88903630T AT 88903630 T AT88903630 T AT 88903630T AT E129074 T1 ATE129074 T1 AT E129074T1
Authority
AT
Austria
Prior art keywords
cells
microspheres
cell population
blood cell
shaped body
Prior art date
Application number
AT88903630T
Other languages
English (en)
Inventor
Kenneth H Kortright
Wallace H Coulter
Carlos Rodriguez
Thomas Russell
Ronald Paul
Original Assignee
Coulter Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Corp filed Critical Coulter Corp
Application granted granted Critical
Publication of ATE129074T1 publication Critical patent/ATE129074T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1024—Counting particles by non-optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1028—Sorting particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ecology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT88903630T 1987-03-13 1988-03-11 Methode zum screening von zellen oder anderen geformten körpern zur spezifizierung von populationen, die ausgewählte charakteristische eigenschaften exprimieren. ATE129074T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2534587A 1987-03-13 1987-03-13

Publications (1)

Publication Number Publication Date
ATE129074T1 true ATE129074T1 (de) 1995-10-15

Family

ID=21825466

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88903630T ATE129074T1 (de) 1987-03-13 1988-03-11 Methode zum screening von zellen oder anderen geformten körpern zur spezifizierung von populationen, die ausgewählte charakteristische eigenschaften exprimieren.

Country Status (10)

Country Link
EP (1) EP0381669B1 (de)
JP (1) JP2716985B2 (de)
KR (1) KR970007078B1 (de)
CN (1) CN1021374C (de)
AT (1) ATE129074T1 (de)
AU (1) AU618736B2 (de)
CA (1) CA1311404C (de)
DE (1) DE3854577T2 (de)
ES (1) ES2011652A6 (de)
WO (1) WO1988007199A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159740A (en) * 1987-03-13 2000-12-12 Coulter Corporation Method and apparatus for screening obscured or partially obscured cells
CA1339840C (en) * 1988-12-16 1998-04-28 Kenneth Kortright Method and apparatus for screening cells or formed bodies with populations expressing selected characteristics
CA1333047C (en) * 1989-04-14 1994-11-15 Thomas Russell Method and apparatus for obtaining at least one white blood cell population analysis
DE69132373T2 (de) * 1990-11-23 2001-03-29 Coulter Corp., Hialeah Verfahren und vorrichtung zur reihensichtung mikroskopischer zellen unter verwendung von lichtstreuenden techniken
JPH06505099A (ja) * 1991-02-22 1994-06-09 クールター　コーポレイション 偏光光散乱手法を用いて微視的細胞をスクリーニングする方法および装置
KR100303608B1 (ko) 1997-05-22 2001-11-22 박호군 혈구세포자동인식방법및장치
WO2006063335A2 (en) * 2004-12-10 2006-06-15 Arryx, Inc. Automated extraction and purification of samples using optical tweezers
GB0908788D0 (en) * 2009-05-21 2009-07-01 Univ Southampton Tissue analysis
FR2986617B1 (fr) 2012-02-02 2015-03-27 Horiba Abx Sas Dispositif et procede pour effectuer des mesures hematologiques et biochimiques a partir d'un echantillon biologique
CN103345654B (zh) * 2013-06-25 2017-02-08 苏州创继生物科技有限公司 一种基于形态学分类计数白细胞的方法
US12449433B2 (en) * 2020-09-01 2025-10-21 Sartorius Bioanalytical Instruments, Inc. Automated method for direct sampling of immune cells from whole blood or other biological samples in microwell plates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3970518A (en) * 1975-07-01 1976-07-20 General Electric Company Magnetic separation of biological particles
US4284412A (en) * 1979-07-13 1981-08-18 Ortho Diagnostics, Inc. Method and apparatus for automated identification and enumeration of specified blood cell subclasses
US4499052A (en) * 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
US4485175A (en) * 1983-01-03 1984-11-27 Coulter Electronics, Inc. Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes
US4599307A (en) * 1983-07-18 1986-07-08 Becton, Dickinson And Company Method for elimination of selected cell populations in analytic cytology
JPS61225656A (ja) * 1985-03-29 1986-10-07 Toshiba Corp 検体検査装置

Also Published As

Publication number Publication date
CA1311404C (en) 1992-12-15
KR890700830A (ko) 1989-04-27
AU618736B2 (en) 1992-01-09
EP0381669B1 (de) 1995-10-11
DE3854577D1 (de) 1995-11-16
CN1021374C (zh) 1993-06-23
ES2011652A6 (es) 1990-02-01
AU1681088A (en) 1988-10-10
EP0381669A4 (en) 1991-01-02
CN88101211A (zh) 1988-10-05
JPH02502573A (ja) 1990-08-16
DE3854577T2 (de) 1996-04-18
WO1988007199A1 (en) 1988-09-22
JP2716985B2 (ja) 1998-02-18
EP0381669A1 (de) 1990-08-16
KR970007078B1 (ko) 1997-05-02

Similar Documents

Publication Publication Date Title
EP1059534B1 (de) Rückwärtsbestimmung von ABO-Blutgruppen
ATE129074T1 (de) Methode zum screening von zellen oder anderen geformten körpern zur spezifizierung von populationen, die ausgewählte charakteristische eigenschaften exprimieren.
DE69903831T2 (de) Trenn- und nachweisverfahren für spermatozoide
Hildebrand et al. Rapid assembly of newly synthesized DNA into chromatin subunits prior to joining of small DNA replication intermediates
FI871111A7 (fi) Häviöitä aiheuttavaa materiaalia sisältävissä näytteissä olevien aine iden magneettiresonanssianalyysi.
IL72499A (en) Kit and method for the detection of bacteria in a biological test sample by nucleic acid hybridization
CA2081565A1 (en) Method and apparatus for screening obscured or partially obscured cells
DE3854326T2 (de) Aufbereitungstechnik für vollblutmuster.
ATE153758T1 (de) Verfahren zur auslese bestimmter zellen oder zellgebilden anhand von populationen mit ausgewählten merkmalen
Levine et al. Flow cytometric analysis of megakaryocyte ploidy. Comparison with Feulgen microdensitometry and discovery that 8N is the predominant ploidy class in guinea pig and monkey marrow
IL94067A0 (en) Method and apparatus for screening cells or formed bodies with populations expressing selected characteristics utilizing at least one sensing parameter
DE3684880D1 (de) Verfahren und apparat zur bestimmung des antikoerperinhalts von blut.
DE69113737T2 (de) Verfahren und vorrichtung zur ausführung des zytotoxizitätsassays auf tumorzellen.
DE602004012161T2 (de) Verkürzung der zeit bis zum vorliegen von blutbankdiagnostikergebnissen
DK481386D0 (da) Fremgangsmaade og reagens til gennemfaerelse af delmaengde-analyse
Edrissian et al. Application of enzyme-linked immunosorbent assay (ELISA) to identification of Anopheles mosquito bloodmeals
Reid et al. Simplified method for recovery of autologous red blood cells from transfused patients
ATE108279T1 (de) Verfahren zum schnellen mischen kleiner volumina zur verbesserung biologischer reaktionen.
Bersu et al. Growth characteristics of the murine trisomy 19 thymus
FI841145A7 (fi) Menetelmä hemoglobiinipitoisuuden kvantitatiiviseksi määrittämiseksi biologisessa näytteessä.
EP0325723A3 (de) Verfahren zur Bestimmung von Blutgerinnungsfaktoren sowie dazu verwendetes Reagens
Krishan Flow cytometry: long-term storage of propidium iodide/citrate-stained material
RU92013706A (ru) Способ оценки активности метаболических процессов в клетке
Jett et al. Quantitation of cell surface antigen density by flow cytometry
Leland et al. Use of Detrended Correspondence Analysis to Identify Factors that Affect the Structure of Aquatic Communities

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee