ATE129496T1 - Herstellung von 2-(2'-thienyl)alkylaminen und deren derivaten zur synthese von 4,5,6,7- thieno(3,2-c>pyridinderivaten. - Google Patents

Herstellung von 2-(2'-thienyl)alkylaminen und deren derivaten zur synthese von 4,5,6,7- thieno(3,2-c>pyridinderivaten.

Info

Publication number: ATE129496T1
Authority: AT; Austria
Prior art keywords: thienyl; derivatives; synthesis; thieno; alkylamines
Prior art date: 1990-01-25

Application number

AT91400147T

Other languages

English (en)

Inventor

Hiralal N Khatri

Bradley S Dehoff

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-01-25

Filing date

1991-01-23

Publication date

1995-11-15

1990-01-25 Priority claimed from US07/470,299 external-priority patent/US5068360A/en

1990-01-25 Priority claimed from US07/470,018 external-priority patent/US4997945A/en

1991-01-23 Application filed by Sanofi Sa filed Critical Sanofi Sa

1995-11-15 Application granted granted Critical

1995-11-15 Publication of ATE129496T1 publication Critical patent/ATE129496T1/de

Links

230000015572 biosynthetic process Effects 0.000 title abstract 3
238000003786 synthesis reaction Methods 0.000 title abstract 3
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical class C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
150000003973 alkyl amines Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical compound CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 abstract 6
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
239000005528 B01AC05 - Ticlopidine Substances 0.000 abstract 1
KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical class NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 1
-1 alkyl ketone Chemical class 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
PHWBOXQYWZNQIN-UHFFFAOYSA-N ticlopidine Chemical compound ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 PHWBOXQYWZNQIN-UHFFFAOYSA-N 0.000 abstract 1
229960005001 ticlopidine Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

AT91400147T 1990-01-25 1991-01-23 Herstellung von 2-(2'-thienyl)alkylaminen und deren derivaten zur synthese von 4,5,6,7- thieno(3,2-c>pyridinderivaten. ATE129496T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/470,299 US5068360A (en)	1990-01-25	1990-01-25	Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno(3,2-C)pyridine derivatives therefrom
US07/470,018 US4997945A (en)	1990-01-25	1990-01-25	Carbamate salts of 2-(2'-thienyl)alkylamines

Publications (1)

Publication Number	Publication Date
ATE129496T1 true ATE129496T1 (de)	1995-11-15

Family

ID=27042936

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91400147T ATE129496T1 (de)	1990-01-25	1991-01-23	Herstellung von 2-(2'-thienyl)alkylaminen und deren derivaten zur synthese von 4,5,6,7- thieno(3,2-c>pyridinderivaten.

Country Status (11)

Country	Link
EP (1)	EP0439404B1 (de)
JP (1)	JP2974432B2 (de)
AT (1)	ATE129496T1 (de)
AU (1)	AU642194B2 (de)
CA (1)	CA2034929A1 (de)
DE (1)	DE69114024T2 (de)
DK (1)	DK0439404T3 (de)
ES (1)	ES2079041T3 (de)
GR (1)	GR3018761T3 (de)
IE (1)	IE69652B1 (de)
NZ (1)	NZ236889A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU1947992A (en) *	1991-07-08	1993-01-14	Syntex (U.S.A.) Inc.	Preparation of 2-(2-thienyl)ethylamine and synthesis of thieno(3,2-c) pyridine derivatives therefrom
FI101150B (fi) *	1991-09-09	1998-04-30	Sankyo Co	Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
US6043368A (en) *	1996-09-04	2000-03-28	Poli Industria Chimica, S.P.A.	Method of making thieno-pyridine derivatives
DE10248479A1 (de) *	2002-10-17	2004-05-06	Consortium für elektrochemische Industrie GmbH	Verfahren zur Herstellung von Thienyl-substituierten sekundären Aminoalkoholen
DE10248480A1 (de) *	2002-10-17	2004-05-06	Consortium für elektrochemische Industrie GmbH	Verfahren zur Herstellung von Thienyl-substituierten sekundären Aminoalkoholen
EP1723141A4 (de) *	2004-03-05	2007-10-10	Ipca Lab Ltd	Grosstechnisches verfahren zur herstellung von clopidogrelhydrogensulfat
CN103787945A (zh) *	2014-01-20	2014-05-14	天津市敬业精细化工有限公司	一种芳香醛的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2299332A1 (fr) *	1975-01-31	1976-08-27	Parcor	Procede de preparation de la (thienyl-2)-2-ethylamine et de ses derives
FR2300090A1 (fr) *	1975-02-07	1976-09-03	Parcor	Procede de preparation de derives de la thienopyridine
FR2608607B1 (fr) *	1986-12-23	1989-04-28	Sanofi Sa	Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues
FR2614619B1 (fr) *	1987-04-29	1989-09-15	Sanofi Sa	Procede de preparation de n-((chloro-2)-benzyl) (thienyl-2)-2 ethylamine
US4906756A (en) *	1988-05-10	1990-03-06	Syntex (U.S.A.) Inc.	2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives
FR2652575B1 (fr) *	1989-09-29	1992-01-24	Sanofi Sa	Procede de preparation d'acides alpha-bromo phenylacetiques.

1991
- 1991-01-23 AT AT91400147T patent/ATE129496T1/de not_active IP Right Cessation
- 1991-01-23 ES ES91400147T patent/ES2079041T3/es not_active Expired - Lifetime
- 1991-01-23 DE DE69114024T patent/DE69114024T2/de not_active Expired - Lifetime
- 1991-01-23 EP EP91400147A patent/EP0439404B1/de not_active Expired - Lifetime
- 1991-01-23 DK DK91400147.4T patent/DK0439404T3/da active
- 1991-01-24 JP JP3041441A patent/JP2974432B2/ja not_active Expired - Lifetime
- 1991-01-24 AU AU69936/91A patent/AU642194B2/en not_active Ceased
- 1991-01-24 IE IE25691A patent/IE69652B1/en not_active IP Right Cessation
- 1991-01-24 NZ NZ236889A patent/NZ236889A/xx unknown
- 1991-01-25 CA CA002034929A patent/CA2034929A1/en not_active Abandoned
1996
- 1996-01-24 GR GR960400159T patent/GR3018761T3/el unknown

Also Published As

Publication number	Publication date
EP0439404B1 (de)	1995-10-25
AU6993691A (en)	1991-08-01
CA2034929A1 (en)	1991-07-26
IE69652B1 (en)	1996-10-02
DK0439404T3 (da)	1996-02-12
IE910256A1 (en)	1991-07-31
EP0439404A3 (en)	1992-04-08
JPH04217974A (ja)	1992-08-07
AU642194B2 (en)	1993-10-14
EP0439404A2 (de)	1991-07-31
JP2974432B2 (ja)	1999-11-10
DE69114024D1 (de)	1995-11-30
ES2079041T3 (es)	1996-01-01
NZ236889A (en)	1993-08-26
GR3018761T3 (en)	1996-04-30
DE69114024T2 (de)	1996-05-30

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Legal Events

Date	Code	Title	Description
2011-04-15	EELA	Cancelled due to lapse of time