ATE129897T1 - Modulation von virus-wirtszell-wechselwirkungen unter verwendung von cyclischen oligosacchariden. - Google Patents

Modulation von virus-wirtszell-wechselwirkungen unter verwendung von cyclischen oligosacchariden.

Info

Publication number
ATE129897T1
ATE129897T1 AT89909095T AT89909095T ATE129897T1 AT E129897 T1 ATE129897 T1 AT E129897T1 AT 89909095 T AT89909095 T AT 89909095T AT 89909095 T AT89909095 T AT 89909095T AT E129897 T1 ATE129897 T1 AT E129897T1
Authority
AT
Austria
Prior art keywords
virus
cells
cyclodextrins
chemically modified
inhibiting
Prior art date
Application number
AT89909095T
Other languages
English (en)
Inventor
Steven A Roth
Paul B Weisz
George Farnbach
David B Weiner
Mark I Greene
William V Williams
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Application granted granted Critical
Publication of ATE129897T1 publication Critical patent/ATE129897T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2006—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT89909095T 1988-07-07 1989-07-06 Modulation von virus-wirtszell-wechselwirkungen unter verwendung von cyclischen oligosacchariden. ATE129897T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21617688A 1988-07-07 1988-07-07
US37300589A 1989-06-28 1989-06-28

Publications (1)

Publication Number Publication Date
ATE129897T1 true ATE129897T1 (de) 1995-11-15

Family

ID=26910735

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89909095T ATE129897T1 (de) 1988-07-07 1989-07-06 Modulation von virus-wirtszell-wechselwirkungen unter verwendung von cyclischen oligosacchariden.

Country Status (10)

Country Link
EP (1) EP0423240B1 (de)
JP (1) JPH04500456A (de)
KR (1) KR900702005A (de)
AT (1) ATE129897T1 (de)
AU (1) AU636850B2 (de)
DE (1) DE68924774T2 (de)
IE (1) IE75688B1 (de)
PT (1) PT91088B (de)
WO (1) WO1990000596A1 (de)
ZA (1) ZA895187B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0447171T3 (da) * 1990-03-15 1994-12-12 Tanabe Seiyaku Co Polysulfat af cyclodextrinderivat og fremgangsmåde til fremstilling deraf
US5248675A (en) * 1990-03-15 1993-09-28 Tanabe Seiyaku Co., Ltd. Polysulfate of cyclodextrin derivative and process for preparing the same
GB9020872D0 (en) * 1990-09-25 1990-11-07 Ml Lab Plc Pharmaceutical compositions and use thereof
FR2669535A1 (fr) * 1990-11-26 1992-05-29 Medgenix Group Sa Utilisation a titre de medicament de macromolecules polysulfonees.
US5312837A (en) * 1991-01-29 1994-05-17 Genelabs Technologies, Inc. Method of treating viral infections with aryl macrocyclic compounds
JP2556236B2 (ja) * 1991-08-29 1996-11-20 田辺製薬株式会社 β−シクロデキストリン誘導体のポリ硫酸エステル及びその製法
AU4803393A (en) * 1992-08-06 1994-03-03 Genelabs Technologies, Inc. Inhibition and treatment of infection by enveloped virus with calix(n) arene compounds
DE9316320U1 (de) * 1993-10-20 1994-01-20 Beni Med Natuerliche Heilmitte Kosmetische Zubereitung in Form von Lippenstiften mit antiviraler Wirkung
US5691316A (en) * 1994-06-01 1997-11-25 Hybridon, Inc. Cyclodextrin cellular delivery system for oligonucleotides
US6835717B2 (en) 2000-03-08 2004-12-28 The Johns Hopkins University School Of Medicine β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
DE10203999A1 (de) * 2002-02-01 2003-08-14 Nutricia Nv Cycloglycane
EP3846853A1 (de) 2018-09-04 2021-07-14 Ecole Polytechnique Federale De Lausanne (Epfl) Viruzide nanopartikel und verwendung davon gegen influenzavirus
WO2023118014A1 (en) 2021-12-20 2023-06-29 Aquilon Pharmaceuticals Inhalable compositions comprising a complex of hpbcd and budesonide or ciclesonide for the treatment or prevention of a respiratory viral disease or lipopolysaccharide-induced inflammation, in particular lipopolysaccharide-induced inflammation associated with a respiratory viral disease
BE1030002B1 (fr) 2021-12-29 2023-09-01 Aquilon Pharmaceuticals Compositions inhalables comprenant un complexe de hpbcd et de budesonide ou ciclesonide pour le traitement ou la prevention d'une maladie virale respiratoire
EP4620476A1 (de) 2022-11-17 2025-09-24 Silva, Renata Moisés Iwamizu Antivirale zusammensetzung mit einschlussverbindungen mit cyclodextrinen als aktivitätsmodulatoren und antiseptische wirkstoffe sowie verwendungen davon
BE1031691B1 (fr) 2023-06-07 2025-01-23 Aquilon Pharmaceuticals Compositions sans conservateur comprenant un complexe de corticostéroïde et d'hpbcd pour le traitement ou la prévention d'une maladie inflammatoire par administration nasale
EP4724038A1 (de) 2023-06-07 2026-04-15 Aquilon Pharmaceuticals Konservierungsmittelfreie zusammensetzungen mit einem komplex aus einem kortikosteroid und hpbcd zur behandlung oder prävention einer entzündungskrankheit durch nasale verabreichung
BE1031693B1 (fr) 2023-06-07 2025-01-23 Aquilon Pharmaceuticals Compositions sans conservateur comprenant un complexe de corticostéroïde et d'hpbcd pour le traitement ou la prévention d'une maladie inflammatoire par administration nasale

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783446A (en) * 1985-11-22 1988-11-08 Neushul Mariculture Incorporated Method for the treatment of AIDS virus and other retroviruses

Also Published As

Publication number Publication date
KR900702005A (ko) 1990-12-05
IE75688B1 (en) 1997-09-10
WO1990000596A1 (en) 1990-01-25
AU4044389A (en) 1990-02-05
PT91088B (pt) 1995-01-31
ZA895187B (en) 1990-04-25
EP0423240A4 (en) 1992-07-22
IE892183L (en) 1990-01-07
DE68924774D1 (de) 1995-12-14
EP0423240A1 (de) 1991-04-24
EP0423240B1 (de) 1995-11-08
AU636850B2 (en) 1993-05-13
JPH04500456A (ja) 1992-01-30
PT91088A (pt) 1990-02-08
DE68924774T2 (de) 1996-05-02

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee