ATE130095T1 - Reagenz zur proteinfällung. - Google Patents

Reagenz zur proteinfällung.

Info

Publication number: ATE130095T1
Authority: AT; Austria
Prior art keywords: precipitation reagent; analytes; determination; test sample; specific binding
Prior art date: 1990-08-15

Application number

AT91113331T

Other languages

English (en)

Inventor

Victoria P Meucci

Mariola B Zajac

Elizabeth A Aloha Gard Simpson

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-15

Filing date

1991-08-08

Publication date

1995-11-15

1991-08-08 Application filed by Abbott Lab filed Critical Abbott Lab

1995-11-15 Application granted granted Critical

1995-11-15 Publication of ATE130095T1 publication Critical patent/ATE130095T1/de

Links

239000003153 chemical reaction reagent Substances 0.000 title abstract 5
230000006920 protein precipitation Effects 0.000 title 1
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 5
238000001556 precipitation Methods 0.000 abstract 4
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
230000002209 hydrophobic effect Effects 0.000 abstract 3
102000014914 Carrier Proteins Human genes 0.000 abstract 2
108091008324 binding proteins Proteins 0.000 abstract 2
238000003018 immunoassay Methods 0.000 abstract 2
230000002452 interceptive effect Effects 0.000 abstract 2
230000009870 specific binding Effects 0.000 abstract 2
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
102000001554 Hemoglobins Human genes 0.000 abstract 1
108010054147 Hemoglobins Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
238000004925 denaturation Methods 0.000 abstract 1
230000036425 denaturation Effects 0.000 abstract 1
WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
230000010287 polarization Effects 0.000 abstract 1
239000002244 precipitate Substances 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
150000003751 zinc Chemical class 0.000 abstract 1
NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 abstract 1
229960001763 zinc sulfate Drugs 0.000 abstract 1
229910000368 zinc sulfate Inorganic materials 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials

Landscapes

Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
General Physics & Mathematics (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Sampling And Sample Adjustment (AREA)
Separation Of Suspended Particles By Flocculating Agents (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

AT91113331T 1990-08-15 1991-08-08 Reagenz zur proteinfällung. ATE130095T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/567,853 US5135875A (en)	1990-08-15	1990-08-15	Protein precipitation reagent

Publications (1)

Publication Number	Publication Date
ATE130095T1 true ATE130095T1 (de)	1995-11-15

Family

ID=24268905

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91113331T ATE130095T1 (de)	1990-08-15	1991-08-08	Reagenz zur proteinfällung.

Country Status (10)

Country	Link
US (1)	US5135875A (de)
EP (1)	EP0471295B1 (de)
JP (1)	JPH04233460A (de)
AT (1)	ATE130095T1 (de)
AU (1)	AU642522B2 (de)
CA (1)	CA2048314A1 (de)
DE (1)	DE69114403T2 (de)
DK (1)	DK0471295T3 (de)
ES (1)	ES2082059T3 (de)
GR (1)	GR3018907T3 (de)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5525519A (en) *	1992-01-07	1996-06-11	Middlesex Sciences, Inc.	Method for isolating biomolecules from a biological sample with linear polymers
US5650288A (en) *	1995-07-14	1997-07-22	Macfarlane; Gordon D.	Immunophilin-bound immunosuppressant assay
CA2230284A1 (en) *	1996-07-03	1998-01-08	Anna P. Jaklitsch	Pretreatment reagents and methods using the same
DE19741447A1 (de) *	1997-09-19	1999-03-25	Dade Behring Marburg Gmbh	Verfahren und Nachweis zur Bestimmung enzymatischer Reaktionen in Urin
US6607891B1 (en)	1998-07-31	2003-08-19	Mitsubishi Chemical Corporation	Method of assaying insulin-like growth factor
BR9804648A (pt) *	1998-11-23	2000-05-30	Fundacao Oswaldo Cruz	Monitorização da obediência do paciente ao tratamento e da biodisponibilidade de drogas pela desproteinização de fluidos corpóreos.
ES2390425T3 (es)	2000-12-22	2012-11-12	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Uso de moléculas de orientación repulsivas (RGM) y sus moduladores
CA2503199A1 (en) *	2002-10-24	2004-05-06	J. Christopher Philips	Techniques for analyzing products containing a coloring agent
WO2004068109A2 (en) *	2003-01-27	2004-08-12	Harvest Technologies Inc	Autologous or homologous coagulant produced from anticoagulated whole blood
EP1603512A2 (de)	2003-03-17	2005-12-14	Albany Molecular Research, Inc.	Neue cyclosporine
WO2006039164A2 (en)	2004-09-29	2006-04-13	Amr Technology, Inc.	Novel cyclosporin analogues and their pharmaceutical uses
US7378391B2 (en)	2004-09-29	2008-05-27	Amr Technology, Inc.	Cyclosporin alkyne analogues and their pharmaceutical uses
WO2006041631A2 (en)	2004-10-06	2006-04-20	Amr Technology, Inc.	Novel cyclosporin alkynes and their utility as pharmaceutical agents
US20060216762A1 (en) *	2005-03-24	2006-09-28	Bayer Healthcare Llc	Extracting reagent for hydrophobic analyte in whole blood
CN101277974A (zh)	2005-09-30	2008-10-01	阿伯特有限及两合公司	排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
US7883855B2 (en) *	2006-07-21	2011-02-08	Abbott Laboratories	Immunosuppressant drug extraction reagent for immunoassays
CA2673296C (en) *	2006-12-29	2012-10-16	Abbott Laboratories	Improved assay for immunosuppressant drugs
CA2673314C (en) *	2006-12-29	2014-03-11	Abbott Laboratories	Non-denaturing lysis reagent for use with capture-in-solution immunoassay
US7914999B2 (en) *	2006-12-29	2011-03-29	Abbott Laboratories	Non-denaturing lysis reagent
WO2008082979A2 (en) *	2006-12-29	2008-07-10	Abbott Laboratories	Diagnostic test for the detection of a molecule or drug in whole blood
JP2010519183A (ja) *	2007-02-06	2010-06-03	インセプトエルエルシー	生理溶液の溶出のためのタンパク質の沈殿を用いる重合
US8288111B2 (en) *	2007-05-24	2012-10-16	Abbott Laboratories	Immunoassays exhibiting reduced cross-reactivity with hydrophobic drug analyte metabolites
US7790401B2 (en) *	2007-08-06	2010-09-07	Siemens Healthcare Diagnostics	Methods for detection of immunosuppressant drugs
US7910378B2 (en) *	2007-12-14	2011-03-22	Siemens Healthcare Diagnostics Inc.	Methods for detection of hydrophobic drugs
BRPI0722361B8 (pt) *	2007-12-19	2021-07-27	Abbott Lab	métodos para avaliar a concentração de um fármaco imunossupressor em uma amostra de sangue humano, composição de reagente de extração e kit de teste
US8409865B2 (en) *	2008-02-25	2013-04-02	Waters Technologies Corp.	Methods and kits for the determination of the presence and quantity of vitamin D analogs in samples
US8962803B2 (en)	2008-02-29	2015-02-24	AbbVie Deutschland GmbH & Co. KG	Antibodies against the RGM A protein and uses thereof
AU2009236653B2 (en) *	2008-04-16	2014-09-25	Biogen Ma Inc.	Method of isolating biomacromolecules using polyalkylene glycol and transition metals
BRPI0910482A2 (pt)	2008-04-29	2019-09-24	Abbott Lab	imunoglobinas de domínio variável duplo e usos das mesmas
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US8741287B2 (en)	2008-06-18	2014-06-03	Abbott Laboratories	PlGF-1 assay and kits and components thereof
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US20110229921A1 (en) *	2010-03-18	2011-09-22	Abbott Laboratories	METHODS OF ASSAYING URINARY NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) IN THE PROGNOSIS OF CADAVERIC KIDNEY TRANSPLANT FUNCTION IN A PATIENT, INCLUDING A PATIENT DIAGNOSED WITH DELAYED GRAFT FUNCTION (DGF), A METHOD OF ASSAYING uNGAL IN THE ASSESSMENT OF RISK OF DGF IN A PATIENT DIAGNOSED WITH EARLY GRAFT FUNCTION (EGF), AND RELATED KITS
JP5786020B2 (ja)	2010-04-16	2015-09-30	アボットジャパン株式会社	関節リウマチを診断する方法および試薬
KR101539684B1 (ko)	2010-05-14	2015-07-27	애브비 인코포레이티드	Ｉｌ－１ 결합 단백질
WO2011163558A1 (en)	2010-06-25	2011-12-29	Abbott Laboratories	Materials and methods for assay of anti-hepatitis c virus (hcv) antibodies
US20120009196A1 (en)	2010-07-08	2012-01-12	Abbott Laboratories	Monoclonal antibodies against hepatitis c virus core protein
UY33492A (es)	2010-07-09	2012-01-31	Abbott Lab	Inmunoglobulinas con dominio variable dual y usos de las mismas
US9110008B2 (en)	2010-07-26	2015-08-18	Los Gatos Research	Method for isotopic analysis of water in bodily fluids
US8735546B2 (en)	2010-08-03	2014-05-27	Abbvie Inc.	Dual variable domain immunoglobulins and uses thereof
WO2012054639A2 (en)	2010-10-22	2012-04-26	T2 Biosystems, Inc.	Nmr systems and methods for the rapid detection of analytes
US8563298B2 (en)	2010-10-22	2013-10-22	T2 Biosystems, Inc.	NMR systems and methods for the rapid detection of analytes
US8409807B2 (en)	2010-10-22	2013-04-02	T2 Biosystems, Inc.	NMR systems and methods for the rapid detection of analytes
US20120115244A1 (en)	2010-11-09	2012-05-10	Abbott Laboratories	Materials and methods for immunoassay of pterins
CN103517921B (zh)	2010-12-21	2017-07-18	Abbvie 公司	IL‑1‑α和‑β双特异性双重可变结构域免疫球蛋白及其用途
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AU2012328917B2 (en)	2011-10-24	2017-05-25	Abbvie Inc.	Bispecific immunobinders directed against TNF and IL-17
JP2014533659A (ja)	2011-10-24	2014-12-15	アッヴィ・インコーポレイテッド	スクレロスチンに対するイムノバインダー
EP2791175A2 (de)	2011-12-14	2014-10-22	Abbvie Deutschland GmbH & Co. KG	Zusammensetzung und verfahren zur diagnose und behandlung von durch eisenmangel bedingten erkrankungen
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US8993248B2 (en)	2011-12-31	2015-03-31	Abbott Laboratories	Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use
NZ714482A (en)	2012-01-27	2017-08-25	Abbvie Inc	Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
US9562271B2 (en)	2012-04-20	2017-02-07	T2 Biosystems, Inc.	Compositions and methods for detection of Candida species
UY34905A (es)	2012-07-12	2014-01-31	Abbvie Inc	Proteínas de unión a il-1
BR112015023239A8 (pt)	2013-03-14	2018-04-17	Abbott Lab	ensaio de combinação de anticorpo-antígeno de hcv e métodos e composições para uso do mesmo
JP2016512241A (ja)	2013-03-14	2016-04-25	アボット・ラボラトリーズＡｂｂｏｔｔＬａｂｏｒａｔｏｒｉｅｓ	改良された抗体検出のためのｈｃｖｎｓ３組換え抗原およびこの突然変異体
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EP2976642A4 (de)	2013-03-15	2016-09-21	Harvard College	Verfahren und zusammensetzungen zur verbesserung der erkennung und/oder aufnahme einer zieleinheit
EP3083658B1 (de)	2013-12-18	2019-05-08	President and Fellows of Harvard College	Detektion gram-positiver bakterien mit crp
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US10435457B2 (en)	2015-08-06	2019-10-08	President And Fellows Of Harvard College	Microbe-binding molecules and uses thereof
WO2017027838A1 (en)	2015-08-13	2017-02-16	President And Fellows Of Harvard College	Microfluidic devices and systems for cell culture and/or assay
WO2017127731A1 (en)	2016-01-21	2017-07-27	T2 Biosystems, Inc.	Nmr methods and systems for the rapid detection of bacteria
US11754478B2 (en)	2018-08-16	2023-09-12	Abb Schweiz Ag	Rapid equilibrator for water isotope analysis
EP3881072A4 (de)	2018-11-16	2022-11-09	President And Fellows Of Harvard College	Moleküle und verfahren zur verbesserten immundetektion von kleinen molekülen wie histamin
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CN120831448B (zh) *	2025-09-18	2026-02-03	江苏硕世生物科技股份有限公司	一种检测脂溶性维生素的方法和试剂盒

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB981144A (en) *	1963-03-25	1965-01-20	Licencia Talalmanyokat	A pharmaceutical formulation for the treatment of dermatophytoses
US3949072A (en) *	1971-03-11	1976-04-06	Tenta Louis T	Topical composition for treatment of seborrheic keratosis
US4022880A (en) *	1973-09-26	1977-05-10	Lever Brothers Company	Anticalculus composition
US4160821A (en) *	1978-02-27	1979-07-10	Johnson & Johnson	Treatment for gingivitis
US4339432A (en) *	1979-06-20	1982-07-13	Lever Brothers Company	Oral mouthwash containing zinc and glycine
WO1983004102A1 (en) *	1982-05-07	1983-11-24	Paragon Diagnostics	Competitive immunofluorescence assay and test kit
US4734378A (en) *	1985-06-26	1988-03-29	Abbott Laboratories	Precipitation of interfering proteins in fluorescence polarization immunoassay for digoxin
NO890029D0 (no) *	1989-01-04	1989-01-04	Axis Research	Nye modifiserte peptider og proteiner for in vitro diagnoser (diabetes).

1990
- 1990-08-15 US US07/567,853 patent/US5135875A/en not_active Expired - Fee Related
1991
- 1991-08-01 CA CA002048314A patent/CA2048314A1/en not_active Abandoned
- 1991-08-08 DE DE69114403T patent/DE69114403T2/de not_active Expired - Fee Related
- 1991-08-08 ES ES91113331T patent/ES2082059T3/es not_active Expired - Lifetime
- 1991-08-08 DK DK91113331.2T patent/DK0471295T3/da active
- 1991-08-08 AT AT91113331T patent/ATE130095T1/de active
- 1991-08-08 EP EP91113331A patent/EP0471295B1/de not_active Expired - Lifetime
- 1991-08-14 AU AU82472/91A patent/AU642522B2/en not_active Ceased
- 1991-08-15 JP JP3205211A patent/JPH04233460A/ja active Pending
1996
- 1996-02-07 GR GR960400313T patent/GR3018907T3/el unknown

Also Published As

Publication number	Publication date
CA2048314A1 (en)	1992-02-16
DE69114403T2 (de)	1996-06-05
US5135875A (en)	1992-08-04
GR3018907T3 (en)	1996-05-31
JPH04233460A (ja)	1992-08-21
AU8247291A (en)	1992-02-20
EP0471295B1 (de)	1995-11-08
AU642522B2 (en)	1993-10-21
EP0471295A1 (de)	1992-02-19
DE69114403D1 (de)	1995-12-14
ES2082059T3 (es)	1996-03-16
DK0471295T3 (da)	1996-04-09

Publication	Publication Date	Title
ATE130095T1 (de)	1995-11-15	Reagenz zur proteinfällung.
Dabrio et al.	2002	Recent developments in quantification methods for metallothionein
US6114180A (en)	2000-09-05	Synthetic calibrators for use in immunoassays, comprising the analytes or partial sequences thereof which are conjugated to inert carrier molecules
ATE113723T1 (de)	1994-11-15	Verfahren zur bestimmung von antikörpern.
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ATE74207T1 (de)	1992-04-15	Verfahren zur bestimmung von hyaluronsaeure.
FI68653B (fi)	1985-06-28	Metod foer bestaemning av tyroxin-bindningsindex i serum och testfoerpackning foer utfoerande av bestaemningen
DE69534263D1 (de)	2005-07-14	Expression kassette eines proteines p30 aus toxoplasma gondii
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Papac	1994	Structural analysis of an intrinsic membrane protein using mass spectrometry: Rhodopsin as a model case.