ATE535813T1 - Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren - Google Patents

Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren

Info

Publication number: ATE535813T1
Authority: AT; Austria
Prior art keywords: reactivity; hydrophobic drug; reduced cross; testing procedures; showing reduced
Prior art date: 2007-05-24

Application number

AT08769692T

Other languages

English (en)

Inventor

Elaine Brate

David Finley

Shelley Holets-Mccormack

David Pacenti

Ryan Piktel

Michelle Shields

Thomas Spring

Philip Wang

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-24

Filing date

2008-05-23

Publication date

2011-12-15

2008-05-23 Application filed by Abbott Lab filed Critical Abbott Lab

2011-12-15 Application granted granted Critical

2011-12-15 Publication of ATE535813T1 publication Critical patent/ATE535813T1/de

Links

229940079593 drug Drugs 0.000 title abstract 4
239000003814 drug Substances 0.000 title abstract 4
239000012491 analyte Substances 0.000 title abstract 3
230000009260 cross reactivity Effects 0.000 title abstract 3
230000002209 hydrophobic effect Effects 0.000 title abstract 3
230000004060 metabolic process Effects 0.000 title 1
238000012956 testing procedure Methods 0.000 title 1
238000003018 immunoassay Methods 0.000 abstract 3
239000002207 metabolite Substances 0.000 abstract 3
229930105110 Cyclosporin A Natural products 0.000 abstract 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
230000001747 exhibiting effect Effects 0.000 abstract 1
239000003018 immunosuppressive agent Substances 0.000 abstract 1
238000000338 in vitro Methods 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9493—Immunosupressants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Pathology (AREA)
General Physics & Mathematics (AREA)
Food Science & Technology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Investigating Or Analysing Biological Materials (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT08769692T 2007-05-24 2008-05-23 Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren ATE535813T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US94006207P	2007-05-24	2007-05-24
PCT/US2008/064688 WO2008147982A1 (en)	2007-05-24	2008-05-23	Immunoassays exhibiting reduced cross-reactivity with hydrophobic drug analyte metabolites

Publications (1)

Publication Number	Publication Date
ATE535813T1 true ATE535813T1 (de)	2011-12-15

Family

ID=39708486

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT08769692T ATE535813T1 (de)	2007-05-24	2008-05-23	Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren

Country Status (7)

Country	Link
US (1)	US8288111B2 (de)
EP (1)	EP2174137B1 (de)
JP (1)	JP5174898B2 (de)
AT (1)	ATE535813T1 (de)
CA (1)	CA2685830C (de)
ES (1)	ES2377167T3 (de)
WO (1)	WO2008147982A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2685830C (en)	2007-05-24	2012-12-18	Abbott Laboratories	Immunoassays exhibiting reduced cross-reactivity with hydrophobic drug analyte metabolites
US7910378B2 (en) *	2007-12-14	2011-03-22	Siemens Healthcare Diagnostics Inc.	Methods for detection of hydrophobic drugs
US8652788B2 (en) *	2009-12-02	2014-02-18	Abbott Laboratories	Assay for diagnosis of cardiac myocyte damage
SG10201501803YA (en) *	2010-03-12	2015-05-28	Immunogen Inc	Cd37-binding molecules and immunoconjugates thereof
JP5798720B2 (ja) *	2010-03-30	2015-10-21	積水メディカル株式会社	ヒトｃ反応性タンパク質（ｃｒｐ）測定用イムノクロマト試薬
CA2815085C (en)	2010-10-22	2022-06-21	T2 Biosystems, Inc.	Nmr systems and methods for the rapid detection of analytes
US8563298B2 (en)	2010-10-22	2013-10-22	T2 Biosystems, Inc.	NMR systems and methods for the rapid detection of analytes
US8409807B2 (en)	2010-10-22	2013-04-02	T2 Biosystems, Inc.	NMR systems and methods for the rapid detection of analytes
US9199234B2 (en)	2011-05-27	2015-12-01	Abbott Point Of Care Inc.	TSH antibodies for point-of-care immunoassay formats
WO2012166200A1 (en)	2011-05-27	2012-12-06	Abbott Point Of Care Inc.	Tsh immunoassays employing scavenging reagents for cross-reacting endocrine glycoprotein hormone analogues
WO2012166199A1 (en)	2011-05-27	2012-12-06	Abbott Point Of Care Inc.	Tsh immunoassays and processes for performing tsh immunoassays in the presence of endogenous contaminants in restricted wash formats
EP2839038B1 (de)	2012-04-20	2019-01-16	T2 Biosystems, Inc.	Zusammensetzungen und verfahren für den nachweis einer candida-spezies
JPWO2014087802A1 (ja) *	2012-12-05	2017-01-05	コニカミノルタ株式会社	表面プラズモン励起増強蛍光分光法（ｓｐｆｓ）を用いた免疫測定法における夾雑物由来の非特異的シグナルの抑制方法
JP7523776B2 (ja)	2016-01-21	2024-07-29	ティー２バイオシステムズ，インコーポレーテッド	細菌を迅速に検出するｎｍｒ法及びシステム
KR102448428B1 (ko) *	2017-01-27	2022-09-30	가부시키가이샤 가네카	내배엽계 세포 집단, 및 다능성 세포로부터 3배엽 중 어느 하나의 세포 집단을 제조하는 방법
JP7233669B2 (ja) *	2017-05-22	2023-03-07	国立大学法人金沢大学	双性イオンを含む難溶性物質溶解剤
ES2991988T3 (es)	2017-10-30	2024-12-05	Takeda Pharmaceuticals Co	Detergentes compatibles con el medio ambiente para la inactivación de virus con envoltura lipídica
US12196768B2 (en)	2017-12-25	2025-01-14	Fujirebio Inc.	Method of testing a blood for macrolide immunosuppressant
CN112014555B (zh) *	2020-08-31	2023-08-08	武汉生之源生物科技股份有限公司	一种酶标抗体缓冲液、试剂r1和肌酸激酶同工酶测定试剂盒
EP4638467A4 (de) *	2022-12-21	2026-03-04	Siemens Healthcare Diagnostics Inc	Cyclosporin-acridinium-ester und verfahren zu ihrer herstellung und verwendung
CN117949646B (zh) *	2023-12-31	2025-03-07	深圳市新产业生物医学工程股份有限公司	试剂组合以及免离心的全血中目标免疫抑制剂的检测方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0290762B1 (de)	1984-10-04	1993-05-12	Sandoz Ag	Cyclosporine
US5169773A (en) *	1984-10-04	1992-12-08	Sandoz Ltd.	Monoclonal antibodies to cyclosporins
US5427960A (en) *	1987-03-27	1995-06-27	Abbott Laboratories	Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
US5239057A (en) *	1987-03-27	1993-08-24	Abbott Laboratories	Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
EP0283801A3 (de)	1987-03-27	1990-05-30	Abbott Laboratories	Fluoreszenz-Polarisations-Test für Cyclosporin A und Metaboliten und verwandte Immunogene und Antikörper
US5006309A (en) *	1988-04-22	1991-04-09	Abbott Laboratories	Immunoassay device with liquid transfer between wells by washing
US5089424A (en) *	1988-06-14	1992-02-18	Abbott Laboratories	Method and apparatus for heterogeneous chemiluminescence assay
US5063081A (en) *	1988-11-14	1991-11-05	I-Stat Corporation	Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
CA2048302A1 (en)	1990-08-15	1992-02-16	Victoria P. Meucci	Solubilization reagent for biological test samples
DE69116034T2 (de) *	1990-08-15	1996-06-20	Abbott Lab	Immunotestreagenzien und Verfahren zur Bestimmung von Cyclosporin
US5135875A (en) *	1990-08-15	1992-08-04	Abbott Laboratories	Protein precipitation reagent
DE69133095T2 (de) *	1990-11-20	2003-03-27	Dade Behring Marburg Gmbh	Cyclosporin-Immunoassay
US5506114A (en) *	1992-02-07	1996-04-09	Osborn Laboratories	Methods and kits for detecting the presence or concentration of biological analytes
US6664114B1 (en) *	1992-08-03	2003-12-16	Sapidyne Instruments, Inc.	Solid phase assay for detection of ligands
US6777198B2 (en) *	2000-10-11	2004-08-17	Pharmacia Diagnostics Ab	Assay method and kit therefor
US7419821B2 (en) *	2002-03-05	2008-09-02	I-Stat Corporation	Apparatus and methods for analyte measurement and immunoassay
US20040018577A1 (en) *	2002-07-29	2004-01-29	Emerson Campbell John Lewis	Multiple hybrid immunoassay
US7682833B2 (en) *	2003-09-10	2010-03-23	Abbott Point Of Care Inc.	Immunoassay device with improved sample closure
US7723099B2 (en) *	2003-09-10	2010-05-25	Abbott Point Of Care Inc.	Immunoassay device with immuno-reference electrode
EP2180323B1 (de) *	2005-04-06	2012-02-01	Abbott Laboratories	Verfahren zur Messung immunsuppressiver Tacrolimus-, Sirolimus- und Cyclosporin-A-Komplexe in einer Blutprobe
US7575875B2 (en) *	2005-10-13	2009-08-18	Abbott Laboratories, Inc.	Method of tacrolimus extraction and quantification using aqueous detergents
US7256008B2 (en) *	2006-01-06	2007-08-14	Abbott Laboratories	Determination of concentration of FK778 by competitive immunoassay
US8022188B2 (en) *	2006-04-24	2011-09-20	Abbott Laboratories	Immunosuppressant binding antibodies and methods of obtaining and using same
US7883855B2 (en) *	2006-07-21	2011-02-08	Abbott Laboratories	Immunosuppressant drug extraction reagent for immunoassays
ES2405364T3 (es)	2006-12-29	2013-05-30	Abbott Laboratories	Ensayo diagnóstico para la detección de una molécula o fármaco en sangre entera
WO2008082984A2 (en)	2006-12-29	2008-07-10	Abbott Laboratories	Non-denaturing lysis reagent for use with capture-in-solution immunoassay
EP2118656B1 (de)	2006-12-29	2012-08-29	Abbott Laboratories	Verbessertes testverfahren für immunsuppressiva
US7914999B2 (en) *	2006-12-29	2011-03-29	Abbott Laboratories	Non-denaturing lysis reagent
CA2685830C (en)	2007-05-24	2012-12-18	Abbott Laboratories	Immunoassays exhibiting reduced cross-reactivity with hydrophobic drug analyte metabolites

2008
- 2008-05-23 CA CA2685830A patent/CA2685830C/en not_active Expired - Fee Related
- 2008-05-23 EP EP08769692A patent/EP2174137B1/de active Active
- 2008-05-23 US US12/126,316 patent/US8288111B2/en active Active
- 2008-05-23 JP JP2010509567A patent/JP5174898B2/ja not_active Expired - Fee Related
- 2008-05-23 AT AT08769692T patent/ATE535813T1/de active
- 2008-05-23 WO PCT/US2008/064688 patent/WO2008147982A1/en not_active Ceased
- 2008-05-23 ES ES08769692T patent/ES2377167T3/es active Active

Also Published As

Publication number	Publication date
WO2008147982A1 (en)	2008-12-04
CA2685830A1 (en)	2008-12-04
US8288111B2 (en)	2012-10-16
JP2010528295A (ja)	2010-08-19
JP5174898B2 (ja)	2013-04-03
ES2377167T3 (es)	2012-03-23
EP2174137B1 (de)	2011-11-30
EP2174137A1 (de)	2010-04-14
CA2685830C (en)	2012-12-18
US20080311676A1 (en)	2008-12-18

Publication	Publication Date	Title
ATE535813T1 (de)	2011-12-15	Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren
HK1202154A1 (en)	2015-09-18	Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients undergoing statin treatment
HK1202157A1 (en)	2015-09-18	Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients not undergoing statin treatment
WO2010090471A3 (ko)	2010-11-18	제1형 당뇨병의 신규한 진단 마커
BR112013023006A2 (pt)	2016-12-06	formulações de suspensões não aquosas de anticorpos de alta concentração e viscosidade reduzida
BR112012029281A2 (pt)	2016-11-29	anticorpo trop-2 anti-humano tendo atividade anti-tumor in vivo
BRPI0906435B8 (pt)	2022-03-15	Anticorpo anti-cd79b quimérico, composto conjugado, formulação farmacêutica, método para determinar a presença da proteína cd79b, ensaio para detectar células de câncer, método para inibir proliferação celular, usos de um anticorpo, de um composto conjugado e de uma formulação farmacêutica, e método para a fabricação de um composto conjugado
ECSP088081A (es)	2008-02-20	Detección de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapéutico correspondiente
EA201101563A1 (ru)	2012-05-30	Безколбовый спектрометр
BR112013021666A2 (pt)	2016-11-22	detecção de capacitância em ensaio eletroquímico com compensação de tempo de amostragem aprimorada
CA2820841C (en)	2018-10-23	Competitive biosensor having elevated sensitivity
NZ602840A (en)	2014-11-28	Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
RU2013105265A (ru)	2014-08-20	Способ диагностики рака поджелудочной железы
EA201590459A1 (ru)	2015-11-30	Специфические антитела к островковому амилоидному полипептиду человека (hiapp) и их применение
BR112012021590A2 (pt)	2016-09-13	detecção de capacitância em ensaio eletroquímico
NZ584558A (en)	2012-10-26	Peptide-lipid constructs and their use in diagnostic and therapeutic applications
WO2010031749A9 (en)	2010-05-14	Compositions and methods for detecting tlr3
WO2012047009A3 (en)	2012-07-19	Diagnostic apparatus and diagnostic method using the same
GB201014837D0 (en)	2010-10-20	Biomarker signatures and uses thereof
ES2684758T3 (es)	2018-10-04	Procedimiento para diagnosticar fibrosis hepática
MX2009012044A (es)	2009-11-18	Eliminacion de interferencia en inmunoensayos causada por anticuerpos anti-carbohidrato.
EP4509835A3 (de)	2025-05-28	Verwendung von protein bei der vorhersage von in-vivo-effekten
WO2013167727A3 (en)	2014-01-09	Method for determining arthritis relapse risk
EA201400571A1 (ru)	2014-11-28	Специфичные к трансресвератролу антитела и их применение
WO2011159741A3 (en)	2012-03-29	Tetranor-pgem/pgam specific immunogens, antibodies, tracers, assay kits and methods for making same