ATE131072T1 - Kerne für technetium-radioarzneimittel. - Google Patents
Kerne für technetium-radioarzneimittel.Info
- Publication number
- ATE131072T1 ATE131072T1 AT90914225T AT90914225T ATE131072T1 AT E131072 T1 ATE131072 T1 AT E131072T1 AT 90914225 T AT90914225 T AT 90914225T AT 90914225 T AT90914225 T AT 90914225T AT E131072 T1 ATE131072 T1 AT E131072T1
- Authority
- AT
- Austria
- Prior art keywords
- technetium
- substituted
- complexes
- radiomedicinal
- cores
- Prior art date
Links
- 229910052713 technetium Inorganic materials 0.000 title abstract 2
- GKLVYJBZJHMRIY-UHFFFAOYSA-N technetium atom Chemical compound [Tc] GKLVYJBZJHMRIY-UHFFFAOYSA-N 0.000 title abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000006165 cyclic alkyl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229940121896 radiopharmaceutical Drugs 0.000 abstract 1
- 239000012217 radiopharmaceutical Substances 0.000 abstract 1
- 230000002799 radiopharmaceutical effect Effects 0.000 abstract 1
- 150000003495 technetium Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898919488A GB8919488D0 (en) | 1989-08-29 | 1989-08-29 | New cores for technetium radiopharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE131072T1 true ATE131072T1 (de) | 1995-12-15 |
Family
ID=10662202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90914225T ATE131072T1 (de) | 1989-08-29 | 1990-08-28 | Kerne für technetium-radioarzneimittel. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0441953B1 (de) |
| JP (2) | JP3221875B2 (de) |
| AT (1) | ATE131072T1 (de) |
| CA (1) | CA2039732A1 (de) |
| DE (1) | DE69024038T2 (de) |
| GB (1) | GB8919488D0 (de) |
| WO (1) | WO1991003262A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07501058A (ja) * | 1991-11-08 | 1995-02-02 | キュレイターズ オブ ザ ユニヴァーシティー オブ ミズーリー | 治療または診断用の放射性薬品の像形成剤の設計における潜在的な使用のための新規な多官能リガンド |
| US5879657A (en) * | 1993-03-30 | 1999-03-09 | The Dupont Merck Pharmaceutical Company | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
| US5750088A (en) * | 1993-03-30 | 1998-05-12 | The Dupont Merck Pharmaceutical Company | Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals |
| US5744120A (en) * | 1993-03-30 | 1998-04-28 | The Dupont Merick Pharmaceutical Company | Ternary radiopharmaceutical complexes |
| US5541289A (en) * | 1994-03-30 | 1996-07-30 | Washington University | Phosphine containing amino acids and peptides and methods of preparing and using same |
| IT1286879B1 (it) * | 1996-11-21 | 1998-07-17 | Consiglio Nazionale Ricerche | Leganti 1,3-difosfinopropanici e complessi da essi formati con metalli di transizione,loro preparazione e uso |
| US6403054B1 (en) * | 1997-05-28 | 2002-06-11 | Bristol-Myers Squibb Pharma Company | Ternary ligand complexes useful as radiopharmaceuticals |
| US6251364B1 (en) | 1999-03-29 | 2001-06-26 | Dupont Pharmaceuticals Company | Ternary ligand complexes useful as radiopharmaceuticals |
| US6534038B2 (en) | 2000-04-07 | 2003-03-18 | Bristol-Myers Squibb Pharma Company | Ternary ligand complexes useful as radiopharmaceuticals |
| US6776977B2 (en) | 2001-01-09 | 2004-08-17 | Bristol-Myers Squibb Pharma Company | Polypodal chelants for metallopharmaceuticals |
| US6517814B2 (en) | 2001-01-09 | 2003-02-11 | Bristol-Myers Squibb Pharma Company | Macrocyclic chelants useful for metallopharmaceuticals |
| US6794553B2 (en) | 2001-11-09 | 2004-09-21 | Shell Oil Company | Process for the telomerization of a conjugated diene, catalyst and bidentate ligand useful therein |
| EP1417977A1 (de) * | 2002-11-07 | 2004-05-12 | BRACCO IMAGING S.p.A. | Radioaktive Übergangsmetall-Imido-Heterodiphosphinkomplexe; deren Herstellung und radiopharmazeutische Zusammensetzungen |
-
1989
- 1989-08-29 GB GB898919488A patent/GB8919488D0/en active Pending
-
1990
- 1990-08-28 WO PCT/GB1990/001330 patent/WO1991003262A1/en not_active Ceased
- 1990-08-28 CA CA002039732A patent/CA2039732A1/en not_active Abandoned
- 1990-08-28 EP EP90914225A patent/EP0441953B1/de not_active Revoked
- 1990-08-28 DE DE69024038T patent/DE69024038T2/de not_active Revoked
- 1990-08-28 AT AT90914225T patent/ATE131072T1/de active
- 1990-08-28 JP JP51331090A patent/JP3221875B2/ja not_active Expired - Lifetime
-
2001
- 2001-05-25 JP JP2001197466A patent/JP3341001B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB8919488D0 (en) | 1989-10-11 |
| JPH04506810A (ja) | 1992-11-26 |
| EP0441953A1 (de) | 1991-08-21 |
| JP3221875B2 (ja) | 2001-10-22 |
| CA2039732A1 (en) | 1991-03-01 |
| EP0441953B1 (de) | 1995-12-06 |
| JP2002060397A (ja) | 2002-02-26 |
| JP3341001B2 (ja) | 2002-11-05 |
| DE69024038D1 (de) | 1996-01-18 |
| WO1991003262A1 (en) | 1991-03-21 |
| DE69024038T2 (de) | 1996-04-25 |
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