ATE132866T1 - 4-(4- oder 6-(trifluormethyl-2-pyridinyl)>-1- piperazinyl-alkyl substituierte laktame - Google Patents

4-(4- oder 6-(trifluormethyl-2-pyridinyl)>-1- piperazinyl-alkyl substituierte laktame

Info

Publication number: ATE132866T1
Authority: AT; Austria
Prior art keywords: pyridinyl; lactames; trifluormethyl; piperazinyl; alkyl substituted
Prior art date: 1990-10-23

Application number

AT91202665T

Other languages

English (en)

Inventor

Patrick Carlier

Michel Combourieu

Claude Poisson

Andre Jean-Claude Monteil

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-23

Filing date

1991-10-15

Publication date

1996-01-15

1991-10-15 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

1996-01-15 Application granted granted Critical

1996-01-15 Publication of ATE132866T1 publication Critical patent/ATE132866T1/de

Links

229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
230000001430 anti-depressive effect Effects 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
229940005513 antidepressants Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000003951 lactams Chemical class 0.000 abstract 1
239000003176 neuroleptic agent Substances 0.000 abstract 1
230000000701 neuroleptic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Psychiatry (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

AT91202665T 1990-10-23 1991-10-15 4-(4- oder 6-(trifluormethyl-2-pyridinyl)>-1- piperazinyl-alkyl substituierte laktame ATE132866T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP90402980		1990-10-23

Publications (1)

Publication Number	Publication Date
ATE132866T1 true ATE132866T1 (de)	1996-01-15

Family

ID=8205767

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91202665T ATE132866T1 (de)	1990-10-23	1991-10-15	4-(4- oder 6-(trifluormethyl-2-pyridinyl)>-1- piperazinyl-alkyl substituierte laktame

Country Status (16)

Country	Link
US (1)	US5180726A (de)
EP (1)	EP0482696B1 (de)
JP (1)	JPH04282379A (de)
KR (1)	KR100226328B1 (de)
AT (1)	ATE132866T1 (de)
AU (1)	AU646611B2 (de)
CA (1)	CA2053980A1 (de)
DE (1)	DE69116302T2 (de)
DK (1)	DK0482696T3 (de)
ES (1)	ES2084763T3 (de)
FI (1)	FI100656B (de)
GR (1)	GR3019559T3 (de)
IE (1)	IE70331B1 (de)
NZ (1)	NZ240298A (de)
PT (1)	PT99298B (de)
ZA (1)	ZA918221B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2701260B1 (fr) *	1993-02-05	1995-05-05	Esteve Labor Dr	Dérivés de 2-[4-(4-azolylbutyl)-1-pipérazinyl]-5-hydroxypyrimidine, leur préparation et leur application en tant que médicaments.
US6114334A (en) *	1995-07-13	2000-09-05	Knoll Aktiengesellschaft	Piperazine derivatives as therapeutic agents
US6150367A (en) *	1997-10-20	2000-11-21	Council Of Scientific & Industrial Research	1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes and their use in medical treatments

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE759371A (fr) *	1969-11-24	1971-05-24	Bristol Myers Co	Azaspirodecanediones heterocycliques et procedes pour leur preparation
FR2429212A1 (fr) *	1978-06-20	1980-01-18	Synthelabo	Derives de phenylpiperazine et leur application en therapeutique
FI791926A7 (fi) *	1978-06-20	1979-12-21	Synthelabo	Fenylpiperazinderivat
US4507303A (en) *	1981-12-22	1985-03-26	Sumitomo Chemical Company, Limited	Succinimide derivatives, compositions and method of use
US4361565A (en) *	1981-12-28	1982-11-30	Mead Johnson & Company	2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
US4619930A (en) *	1985-01-16	1986-10-28	Bristol-Myers Company	Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
US4675403A (en) *	1985-10-16	1987-06-23	American Home Products Corporation	3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity
US4732984A (en) *	1985-10-17	1988-03-22	American Home Products Corporation	Piperazinoisothiazolones with psychotropic activity
CA1305148C (en) *	1987-08-19	1992-07-14	Hiromu Matsumura	Carbamoylpyrrolidone derivatives and drugs for senile dementia

1991
- 1991-10-15 EP EP91202665A patent/EP0482696B1/de not_active Expired - Lifetime
- 1991-10-15 DE DE69116302T patent/DE69116302T2/de not_active Expired - Fee Related
- 1991-10-15 DK DK91202665.5T patent/DK0482696T3/da active
- 1991-10-15 AT AT91202665T patent/ATE132866T1/de not_active IP Right Cessation
- 1991-10-15 ES ES91202665T patent/ES2084763T3/es not_active Expired - Lifetime
- 1991-10-15 ZA ZA918221A patent/ZA918221B/xx unknown
- 1991-10-16 IE IE362891A patent/IE70331B1/en not_active IP Right Cessation
- 1991-10-17 US US07/777,963 patent/US5180726A/en not_active Expired - Fee Related
- 1991-10-21 NZ NZ240298A patent/NZ240298A/xx unknown
- 1991-10-22 PT PT99298A patent/PT99298B/pt not_active IP Right Cessation
- 1991-10-22 AU AU86088/91A patent/AU646611B2/en not_active Ceased
- 1991-10-22 CA CA002053980A patent/CA2053980A1/en not_active Abandoned
- 1991-10-22 FI FI914971A patent/FI100656B/fi active
- 1991-10-22 KR KR1019910018561A patent/KR100226328B1/ko not_active Expired - Fee Related
- 1991-10-23 JP JP3275798A patent/JPH04282379A/ja active Pending
1996
- 1996-04-04 GR GR960400938T patent/GR3019559T3/el unknown

Also Published As

Publication number	Publication date
KR100226328B1 (ko)	1999-10-15
KR920008030A (ko)	1992-05-27
DE69116302T2 (de)	1996-05-30
AU8608891A (en)	1992-04-30
DE69116302D1 (de)	1996-02-22
ZA918221B (en)	1992-06-24
US5180726A (en)	1993-01-19
ES2084763T3 (es)	1996-05-16
DK0482696T3 (da)	1996-05-20
GR3019559T3 (en)	1996-07-31
PT99298A (pt)	1992-08-31
FI914971A0 (fi)	1991-10-22
AU646611B2 (en)	1994-02-24
IE913628A1 (en)	1992-05-22
IE70331B1 (en)	1996-11-13
FI100656B (fi)	1998-01-30
CA2053980A1 (en)	1992-04-24
EP0482696B1 (de)	1996-01-10
EP0482696A1 (de)	1992-04-29
JPH04282379A (ja)	1992-10-07
PT99298B (pt)	1999-04-30
FI914971L (fi)	1992-04-24
NZ240298A (en)	1993-02-25

Legal Events

Date	Code	Title	Description
1996-06-15	UEP	Publication of translation of european patent specification
2001-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
FI933357A0 (fi)	1993-07-27	Foerfarande foer framstaellning av benzamider
LU91362I2 (fr)	2007-11-12	Palipéridone et ses dérivés pharmaceutiquement acceptables (INVEGA)
ATE122334T1 (de)	1995-05-15	4-(4-alkoxyphenyl)-2-butylaminderivate und deren herstellungsverfahren.
DK0656353T3 (da)	1999-02-01	Aminoquinolinderivater med en virkning mod malariafremkaldere
ATE402151T1 (de)	2008-08-15	2-(arylphenyl)amino-imidazolin-derivate
DK208287A (da)	1987-11-16	4(5)-substituerede imidazolderivater og fremgangsmaade til fremstilling deraf
DE69617226D1 (de)	2002-01-03	Piperidinderivate.
ATE132866T1 (de)	1996-01-15	4-(4- oder 6-(trifluormethyl-2-pyridinyl)>-1- piperazinyl-alkyl substituierte laktame
FI962768A0 (fi)	1996-07-05	N-(2-ftaali-imidoetyyli)substituoituja transpiperidiini-2,5-dikarboksylaatteja
DE3471929D1 (de)	1988-07-14	Imidazolinone derivatives as histamine h2-antagonists
ATE92058T1 (de)	1993-08-15	Pyrimidin-derivate, 2-(4-(alpha-heteroaryl-alphaaryl-(alpha-alkyl)-methoxy)-butyl)-1-piperaziny > mit serotoninergischer wirkung.
HUT53089A (en)	1990-09-28	Process for producing cyclic guanidine derivatives of calcium-antagonistic activity and pharmaceutical compositions containing them
FR2823749B1 (fr)	2004-02-20	Phenyl- et pyridyl-piperidines, procede pour leur preparation et compositions pharmaceutiques les contenant