ATE133994T1 - An karzinoma assoziierte antigene und antikörper, die diese antigene erkennen - Google Patents

An karzinoma assoziierte antigene und antikörper, die diese antigene erkennen

Info

Publication number
ATE133994T1
ATE133994T1 AT89901006T AT89901006T ATE133994T1 AT E133994 T1 ATE133994 T1 AT E133994T1 AT 89901006 T AT89901006 T AT 89901006T AT 89901006 T AT89901006 T AT 89901006T AT E133994 T1 ATE133994 T1 AT E133994T1
Authority
AT
Austria
Prior art keywords
antigens
carcinoma
recognize
epitopes
antibodies
Prior art date
Application number
AT89901006T
Other languages
English (en)
Inventor
Jack R Wands
Hiroshi Takahashi
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of ATE133994T1 publication Critical patent/ATE133994T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1048—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell determinant being a carcino embryonic antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT89901006T 1987-12-09 1988-12-09 An karzinoma assoziierte antigene und antikörper, die diese antigene erkennen ATE133994T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13077787A 1987-12-09 1987-12-09
US18091388A 1988-04-13 1988-04-13
US20318288A 1988-06-07 1988-06-07

Publications (1)

Publication Number Publication Date
ATE133994T1 true ATE133994T1 (de) 1996-02-15

Family

ID=27384055

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89901006T ATE133994T1 (de) 1987-12-09 1988-12-09 An karzinoma assoziierte antigene und antikörper, die diese antigene erkennen

Country Status (9)

Country Link
US (1) US5703213A (de)
EP (1) EP0420848B1 (de)
JP (1) JPH05503837A (de)
AT (1) ATE133994T1 (de)
AU (1) AU625595B2 (de)
CA (1) CA1340110C (de)
DE (1) DE3854999T2 (de)
NZ (1) NZ227266A (de)
WO (1) WO1989005156A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05317082A (ja) * 1991-08-06 1993-12-03 Toray Ind Inc モノクローナル抗体およびその用途
US20040001842A1 (en) * 1997-05-12 2004-01-01 Dov Michaeli Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors
HUP0002760A3 (en) 1997-05-12 2003-03-28 Aphton Corp Woodland Immunogenic compositions to the cck-b/gastrin-receptor and methods for the treatment of tumors
CA2441228A1 (en) 2001-03-23 2002-10-03 Aphton Corporation Combination treatment of pancreatic cancer
US20090191232A1 (en) 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
US20030021786A1 (en) * 2001-07-09 2003-01-30 Gevas Philip C. Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus
WO2004088326A2 (en) * 2003-03-28 2004-10-14 Aphton Corporation Gastrin hormone immunoassays
US20050226883A1 (en) * 2004-02-06 2005-10-13 Paul Averback Humanized antibody
DK1794586T3 (da) 2004-09-22 2013-05-13 Cancer Advances Inc Monoklonale antistoffer til progastrin
EP3624841A4 (de) 2017-06-15 2021-01-27 Cancer Advances, Inc., Zusammensetzungen und verfahren zur induzierung humoraler und zellulärer immunitäten gegen tumore und krebs
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4349528A (en) * 1979-11-21 1982-09-14 The Wistar Institute Monocolonal hybridoma antibody specific for high molecular weight carcinoembryonic antigen
US4444744A (en) * 1980-03-03 1984-04-24 Goldenberg Milton David Tumor localization and therapy with labeled antibodies to cell surface antigens
JPS5729949A (en) * 1980-07-30 1982-02-18 Nippon Koutai Kenkyusho:Kk Determination of sugar branch related to cancer and diagnostic technique of cancer
US4661586A (en) * 1981-11-17 1987-04-28 The Board Of Trustees Of The Leland Stanford Junior University Monoclonal anti-idiotype antibodies
US4485093A (en) * 1982-08-13 1984-11-27 Runge Richard G Immunotoxin conjugate which comprises arsanilic acid, useful for treating malignant tumors, particularly pancreatic cancer
US4579827A (en) * 1983-03-11 1986-04-01 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies to human gastrointestinal cancers and hybridoma method of production of the monoclonal antibodies
US4536479A (en) * 1983-03-22 1985-08-20 E. I. Du Pont De Nemours And Company Use of anti-idiotype antibodies in immunoassays
US4683200A (en) * 1984-05-17 1987-07-28 Setsuo Hirohashi Monoclonal antibody to human cancer antigen and method for producing same
US4695538A (en) * 1984-06-01 1987-09-22 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies to cell surface antigens
US4877611A (en) * 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
US5212085A (en) * 1987-12-09 1993-05-18 The General Hospital Corporation Sf-25 colon adenocarcinoma antigen, and antibodies with recognize this antigen

Also Published As

Publication number Publication date
DE3854999D1 (de) 1996-03-21
NZ227266A (en) 1992-02-25
AU2911289A (en) 1989-07-05
CA1340110C (en) 1998-11-03
US5703213A (en) 1997-12-30
EP0420848A4 (en) 1991-06-05
EP0420848A1 (de) 1991-04-10
WO1989005156A1 (en) 1989-06-15
EP0420848B1 (de) 1996-02-07
DE3854999T2 (de) 1996-11-14
JPH05503837A (ja) 1993-06-24
AU625595B2 (en) 1992-07-16

Similar Documents

Publication Publication Date Title
DE69434286D1 (de) Immunologische bestimmungen von prostata-spezifischem antigen
ATE94205T1 (de) Monoklonale antikoerper gegen melanoma-assoziierte antigene, hybridzellinien, die diese antikoerper produzieren, und ihre verwendung.
NO963168D0 (no) Immunstimulatoriske monoklonale antistoffer
SI0970126T1 (en) Novel method for the production of antihuman antigen receptors and uses thereof
ZA945364B (en) Antibodies specific for human prostate glandular kallikrein
ATE143052T1 (de) Chimärisches murine-mensch-immunoglobulin, spezifisch für tumorassoziertes 17-1a antigen
NO862641D0 (no) Monoklonalt antistoff for et antigen tilknyttet human karsinoma tumor.
ES520692A0 (es) Un procedimiento de preparacion de conjugados inmunoenzimaticos.
PL313260A1 (en) Monoclonal antibodies having properties making them able to cause apoptosis
GB2128630A (en) Method of affinity purification employing monoclonal antibodies
BG101024A (bg) Моноклонално антитяло срещу сd44v6
ATE128986T1 (de) Antigen sf-25 des darm-adenokarzinoms sowie antikörper, die dieses antigen erkennen.
KR850700111A (ko) 종양 및 비루스에 대하여 항-이디오 타입 항체로써 유도되는 면역반응
OA08485A (fr) Monoclonal antibodies and antigen for human non-small cell lung carcinoma and certain other human carcinomas.
ATE133994T1 (de) An karzinoma assoziierte antigene und antikörper, die diese antigene erkennen
DE3586216D1 (de) Brusttumorassoziiertes antigen und monoklonale antikoerper dazu.
DE3855280D1 (de) Von mca 16-88 erkanntes antigen
ATE138200T1 (de) Das von mca-28a32 erkannte antigen
ES552073A0 (es) Un procedimiento para purificar urocinasa
ES8106834A1 (es) Un metodo de producir un antisuero que tiene una mejor cua- lidad aglutinante
KR950016780A (ko) 신규 모노클로날 항체
SE9500148D0 (sv) Antibodies for use in cancer therapy and diagnosis
LV10202A (lv) Cilveka karcinomas asociets antigens un to saistosa antiviela
IT8821547A0 (it) Metodo immunologico per la determinazione di anticorpi anti antigeni di microorganismi, mediante anticorpi antiidiotipo e mezzi adatti allo scopo.
EP0259773A3 (de) Ein Antikörper spezifisch gegen ein Krebsantigen