ATE135015T1 - Vasodilatierende und immunsupprimierende peptide - Google Patents

Vasodilatierende und immunsupprimierende peptide

Info

Publication number: ATE135015T1
Authority: AT; Austria
Prior art keywords: proteins; immunosumptimizing; vasodilating; peptides; mammal
Prior art date: 1989-06-29

Application number

AT90911134T

Other languages

English (en)

Inventor

Ethan A Lerner

Heinz G Remold

Jose M C Ribeiro

Richard G Titus

Original Assignee

Harvard College

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-29

Filing date

1990-06-29

Publication date

1996-03-15

1990-06-29 Application filed by Harvard College filed Critical Harvard College

1996-03-15 Application granted granted Critical

1996-03-15 Publication of ATE135015T1 publication Critical patent/ATE135015T1/de

Links

102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
230000000304 vasodilatating effect Effects 0.000 title 1
102000004169 proteins and genes Human genes 0.000 abstract 4
108090000623 proteins and genes Proteins 0.000 abstract 4
241000124008 Mammalia Species 0.000 abstract 3
102100038518 Calcitonin Human genes 0.000 abstract 2
108060001064 Calcitonin Proteins 0.000 abstract 1
108090000932 Calcitonin Gene-Related Peptide Proteins 0.000 abstract 1
241000255134 Lutzomyia <genus> Species 0.000 abstract 1
241000255634 Lutzomyia longipalpis Species 0.000 abstract 1
BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 abstract 1
229960004015 calcitonin Drugs 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
230000000415 inactivating effect Effects 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1
239000004576 sand Substances 0.000 abstract 1
230000024883 vasodilation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Cardiology (AREA)
Insects & Arthropods (AREA)
Zoology (AREA)
Heart & Thoracic Surgery (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Tropical Medicine & Parasitology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT90911134T 1989-06-29 1990-06-29 Vasodilatierende und immunsupprimierende peptide ATE135015T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US37408089A	1989-06-29	1989-06-29

Publications (1)

Publication Number	Publication Date
ATE135015T1 true ATE135015T1 (de)	1996-03-15

Family

ID=23475190

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90911134T ATE135015T1 (de)	1989-06-29	1990-06-29	Vasodilatierende und immunsupprimierende peptide

Country Status (7)

Country	Link
EP (1)	EP0479899B1 (de)
JP (1)	JPH06502385A (de)
AT (1)	ATE135015T1 (de)
AU (1)	AU5966490A (de)
CA (1)	CA2063260A1 (de)
DE (1)	DE69025763T2 (de)
WO (1)	WO1991000293A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5397772A (en) *	1989-06-29	1995-03-14	The President And Fellows Of Harvard College	Vasodilatory peptides from the salivary gland of the sand fly Lutzomyia longipalpis
US5294543A (en) *	1992-04-08	1994-03-15	The General Hospital Corporation	Inhibitor of platelet aggregation
CA2155866A1 (en) *	1993-02-12	1994-08-18	Jose M. C. Ribeiro	Method of enhancing hair growth and hair revitalizing compositions comprising lutzomyia protein
US5480864A (en) *	1993-08-06	1996-01-02	Shiseido Co., Ltd.	Modified maxadilan protein, its preparation and use, and DNA encoding the protein
KR100361933B1 (ko)	1993-09-08	2003-02-14	라 졸라 파마슈티칼 컴파니	화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
KR950007873A (ko) *	1993-09-20	1995-04-15	후꾸하라 요시하루	생리 활성 물질 지속 방출형의 의약 제제
US6462016B1 (en)	1995-10-06	2002-10-08	Shiseido Company, Ltd.	Method for screening agonist or antagonist of the maxadilan receptor participating in vasodilating action, and compound found by the method

1990
- 1990-06-29 AT AT90911134T patent/ATE135015T1/de not_active IP Right Cessation
- 1990-06-29 CA CA002063260A patent/CA2063260A1/en not_active Abandoned
- 1990-06-29 DE DE69025763T patent/DE69025763T2/de not_active Expired - Fee Related
- 1990-06-29 AU AU59664/90A patent/AU5966490A/en not_active Abandoned
- 1990-06-29 JP JP2510163A patent/JPH06502385A/ja active Pending
- 1990-06-29 EP EP90911134A patent/EP0479899B1/de not_active Expired - Lifetime
- 1990-06-29 WO PCT/US1990/003746 patent/WO1991000293A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP0479899B1 (de)	1996-03-06
WO1991000293A1 (en)	1991-01-10
CA2063260A1 (en)	1990-12-30
AU5966490A (en)	1991-01-17
JPH06502385A (ja)	1994-03-17
DE69025763T2 (de)	1996-09-05
EP0479899A1 (de)	1992-04-15
DE69025763D1 (de)	1996-04-11

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Legal Events

Date	Code	Title	Description
1996-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties