ATE135573T1 - Verwendung von indazol-methoxyalkansäure zur herstellung eines arzneimittels zur behandlung von autoimmunkrankheiten - Google Patents

Verwendung von indazol-methoxyalkansäure zur herstellung eines arzneimittels zur behandlung von autoimmunkrankheiten

Info

Publication number
ATE135573T1
ATE135573T1 AT92201037T AT92201037T ATE135573T1 AT E135573 T1 ATE135573 T1 AT E135573T1 AT 92201037 T AT92201037 T AT 92201037T AT 92201037 T AT92201037 T AT 92201037T AT E135573 T1 ATE135573 T1 AT E135573T1
Authority
AT
Austria
Prior art keywords
treatment
autoimmune diseases
methoxyalcaneous
indazole
acid
Prior art date
Application number
AT92201037T
Other languages
English (en)
Inventor
Bruno Silvestrini
Original Assignee
Angelini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricerche Spa filed Critical Angelini Ricerche Spa
Application granted granted Critical
Publication of ATE135573T1 publication Critical patent/ATE135573T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92201037T 1991-04-22 1992-04-11 Verwendung von indazol-methoxyalkansäure zur herstellung eines arzneimittels zur behandlung von autoimmunkrankheiten ATE135573T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911101A IT1253703B (it) 1991-04-22 1991-04-22 Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie

Publications (1)

Publication Number Publication Date
ATE135573T1 true ATE135573T1 (de) 1996-04-15

Family

ID=11359721

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92201037T ATE135573T1 (de) 1991-04-22 1992-04-11 Verwendung von indazol-methoxyalkansäure zur herstellung eines arzneimittels zur behandlung von autoimmunkrankheiten

Country Status (16)

Country Link
US (1) US5278183A (de)
EP (1) EP0510748B1 (de)
JP (1) JP3056879B2 (de)
KR (1) KR100210199B1 (de)
AT (1) ATE135573T1 (de)
AU (1) AU657524B2 (de)
BG (1) BG61366B2 (de)
CA (1) CA2066304C (de)
CZ (1) CZ280613B6 (de)
DE (1) DE69209128T2 (de)
DK (1) DK0510748T3 (de)
IL (1) IL101660A (de)
IT (1) IT1253703B (de)
NZ (1) NZ242392A (de)
SK (1) SK278546B6 (de)
ZA (1) ZA922740B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2723315B1 (fr) 1994-08-02 1996-10-25 Cird Galderma Procede et composition pour stimuler la differenciation des cellules preadipocytaires et traitements therapeutiques associes
IT1276031B1 (it) * 1995-10-31 1997-10-24 Angelini Ricerche Spa Composizione farmaceutica per il trattamento delle malattie autoimmuni
IT1293795B1 (it) * 1997-07-28 1999-03-10 Angelini Ricerche Spa Farmaco attivo nel ridurre la produzione di proteina mcp-1
CN1589269A (zh) * 2001-10-26 2005-03-02 康涅狄格大学 杂1,2－二氢化茚:一类新型有效的大麻配体
ITMI20062254A1 (it) 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
EP2262778B8 (de) 2008-03-07 2020-01-01 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. 1-benzyl-3-hydroxymethylindazolderivate und ihre verwendung bei der behandlung von auf der expression von mcp-1, cx3cr1 und p40 basierten erkrankungen
US8314099B2 (en) 2008-03-07 2012-11-20 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1 and CX3CR1
PL2254870T3 (pl) * 2008-03-07 2016-07-29 Acraf Pochodne 1-benzylo-3-hydroksymetyloindazolu i ich zastosowanie w leczeniu chorób opartych na ekspresji MCP-1, CX3CR1
PL2462119T3 (pl) 2009-08-03 2014-10-31 Acraf Sposób wytwarzania 1-benzylo-3-hydroksymetylo-1H-indazolu i jego pochodnych oraz potrzebnych magnezowych związków pośrednich
UA108742C2 (uk) * 2009-09-23 2015-06-10 Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
EP3990433A4 (de) 2019-06-25 2023-07-26 Translatum Medicus Inc. Verfahren zur herstellung von 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropansäure und ihren derivaten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194564B (it) * 1983-04-18 1988-09-22 Acraf Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa
DE3664036D1 (en) * 1985-02-12 1989-07-27 Acraf (1-phenylmethyl-5-hydroxy-1h-indazol-3-yl)-oxyacetic acid and salts thereof for use as a medicament, and pharmaceutical compositions containing them
IT1230441B (it) * 1989-02-07 1991-10-23 Acraf Eteri della serie dell'indazolo

Also Published As

Publication number Publication date
SK278546B6 (en) 1997-09-10
US5278183A (en) 1994-01-11
IL101660A (en) 1996-08-04
EP0510748A1 (de) 1992-10-28
CS122792A3 (en) 1992-11-18
DE69209128D1 (de) 1996-04-25
KR920019350A (ko) 1992-11-19
AU1488392A (en) 1992-10-29
CA2066304A1 (en) 1992-10-23
JPH0640915A (ja) 1994-02-15
EP0510748B1 (de) 1996-03-20
CZ280613B6 (cs) 1996-03-13
JP3056879B2 (ja) 2000-06-26
ITMI911101A0 (it) 1991-04-22
BG61366B2 (bg) 1997-06-30
KR100210199B1 (ko) 1999-07-15
DK0510748T3 (da) 1996-07-22
ZA922740B (en) 1992-12-30
ITMI911101A1 (it) 1992-10-22
IT1253703B (it) 1995-08-23
AU657524B2 (en) 1995-03-16
CA2066304C (en) 2005-06-21
DE69209128T2 (de) 1996-11-28
NZ242392A (en) 1997-06-24

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