ATE136591T1 - Verfahren zur diagnose und zur amplifikation, das das problem einer fehlpaarung zwischen primer und zielsequenz am 3'-ende des primers überwindet - Google Patents

Verfahren zur diagnose und zur amplifikation, das das problem einer fehlpaarung zwischen primer und zielsequenz am 3'-ende des primers überwindet

Info

Publication number: ATE136591T1
Authority: AT; Austria
Prior art keywords: primer; mismatch; nucleic acid; overcomes; diagnosis
Prior art date: 1989-09-12

Application number

AT90202372T

Other languages

English (en)

Inventor

John Bruce C O Eastman Findlay

State Street Department

Lynn C O Eastman Kod Bergmeyer

Original Assignee

Johnson & Johnson Clin Diag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-12

Filing date

1990-09-06

Publication date

1996-04-15

1990-09-06 Application filed by Johnson & Johnson Clin Diag filed Critical Johnson & Johnson Clin Diag

1996-04-15 Application granted granted Critical

1996-04-15 Publication of ATE136591T1 publication Critical patent/ATE136591T1/de

Links

238000000034 method Methods 0.000 title abstract 4
230000003321 amplification Effects 0.000 title 1
238000003745 diagnosis Methods 0.000 title 1
238000003199 nucleic acid amplification method Methods 0.000 title 1
150000007523 nucleic acids Chemical class 0.000 abstract 3
108020004707 nucleic acids Proteins 0.000 abstract 2
102000039446 nucleic acids Human genes 0.000 abstract 2
RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical compound CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 abstract 2
108020004414 DNA Proteins 0.000 abstract 1
108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
239000013610 patient sample Substances 0.000 abstract 1
229940113082 thymine Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/948—Microorganisms using viruses or cell lines
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Immunology (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Genetics & Genomics (AREA)
AIDS & HIV (AREA)
Chemical Kinetics & Catalysis (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Analysing Materials By The Use Of Radiation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Road Signs Or Road Markings (AREA)
Coating Apparatus (AREA)
Lubricants (AREA)
Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

AT90202372T 1989-09-12 1990-09-06 Verfahren zur diagnose und zur amplifikation, das das problem einer fehlpaarung zwischen primer und zielsequenz am 3'-ende des primers überwindet ATE136591T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/406,221 US5196305A (en)	1989-09-12	1989-09-12	Diagnostic and amplification methods using primers having thymine at 3' end to overcome primer-target mismatch at the 3' end

Publications (1)

Publication Number	Publication Date
ATE136591T1 true ATE136591T1 (de)	1996-04-15

Family

ID=23607049

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90202372T ATE136591T1 (de)	1989-09-12	1990-09-06	Verfahren zur diagnose und zur amplifikation, das das problem einer fehlpaarung zwischen primer und zielsequenz am 3'-ende des primers überwindet

Country Status (11)

Country	Link
US (1)	US5196305A (de)
EP (1)	EP0417842B1 (de)
JP (1)	JPH07102139B2 (de)
KR (1)	KR910006497A (de)
AT (1)	ATE136591T1 (de)
CA (1)	CA2024459A1 (de)
DE (1)	DE69026449T2 (de)
DK (1)	DK0417842T3 (de)
FI (1)	FI904494A7 (de)
IE (1)	IE903310A1 (de)
SG (1)	SG96532A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5143854A (en) *	1989-06-07	1992-09-01	Affymax Technologies N.V.	Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5547839A (en) *	1989-06-07	1996-08-20	Affymax Technologies N.V.	Sequencing of surface immobilized polymers utilizing microflourescence detection
CA2054983A1 (en) *	1990-11-08	1992-05-09	Sotoo Asakura	Suspendible composition and process for preparing the same
DE69132905T2 (de) *	1990-12-06	2002-08-01	Affymetrix, Inc. (N.D.Ges.D.Staates Delaware)	Detektion von Nukleinsäuresequenzen
CA2065719A1 (en)	1991-04-30	1992-10-31	John B. Findlay	Nucleic acid amplification and detection methods using rapid polymerase chain reaction cycle
US5523389A (en) *	1992-09-29	1996-06-04	Isis Pharmaceuticals, Inc.	Inhibitors of human immunodeficiency virus
US6174668B1 (en) *	1993-05-14	2001-01-16	Johnson & Johnson Clinical Diagnostics, Inc.	Diagnostic compositions, elements, methods and test kits for amplification and detection of two or more target DNA's using primers having matched melting temperatures
US5403707A (en) *	1993-05-14	1995-04-04	Eastman Kodak Company	Diagnostic compositions, elements, methods and test kits for amplification and detection of retroviral DNA using primers having matched melting temperatures
US5512430A (en) *	1993-07-13	1996-04-30	Hri Research, Inc.	Diagnostic array for virus infection
US6401267B1 (en) *	1993-09-27	2002-06-11	Radoje Drmanac	Methods and compositions for efficient nucleic acid sequencing
FR2720077B1 (fr) *	1994-05-18	1996-08-09	Univ Rennes	Procédé d'amplification enzymatique in vitro d'un fragment d'ADN à l'aide d'amorces en escalier.
US6287850B1 (en) *	1995-06-07	2001-09-11	Affymetrix, Inc.	Bioarray chip reaction apparatus and its manufacture
DE69527585T2 (de) *	1994-06-08	2003-04-03	Affymetrix, Inc.	Verfahren und Vorrichtung zum Verpacken von Chips
US5545531A (en) *	1995-06-07	1996-08-13	Affymax Technologies N.V.	Methods for making a device for concurrently processing multiple biological chip assays
US6720149B1 (en) *	1995-06-07	2004-04-13	Affymetrix, Inc.	Methods for concurrently processing multiple biological chip assays
AR005140A1 (es)	1995-12-21	1999-04-14	Cornell Res Foundation Inc	Una molecula de adn aislada que codifica una proteina o polipeptido de un virus del enrollamiento de la hoja de la vid, un sistema de expresion, unacelula huesped, un transplante de vastago o de rizoma transgenico que incluye dicha molecula de adn, metodo para producir dicho transplante, un metodo para
US6660233B1 (en) *	1996-01-16	2003-12-09	Beckman Coulter, Inc.	Analytical biochemistry system with robotically carried bioarray
CA2222769C (en) *	1997-01-17	2001-06-12	F. Hoffmann-La Roche Ag	Primers for the detection of hiv-1
US6093544A (en)	1997-05-20	2000-07-25	Cornell Research Foundation, Inc.	Rupestris stem pitting associated virus nucleic acids, proteins, and their uses
ZA984232B (en)	1997-05-20	1998-12-01	Cornell Res Foundation Inc	Grapevine leafroll virus type 2 proteins coding sequences and methods
US20030148301A1 (en) *	1999-12-10	2003-08-07	Toshiya Aono	Method of detecting nucleotide polymorphism
US8652774B2 (en) *	2003-04-16	2014-02-18	Affymetrix, Inc.	Automated method of manufacturing polyer arrays
DE602004018631D1 (de)	2003-04-24	2009-02-05	Afshin Ahmadian	En
US8029454B2 (en)	2003-11-05	2011-10-04	Baxter International Inc.	High convection home hemodialysis/hemofiltration and sorbent system
US7572990B2 (en) *	2007-03-30	2009-08-11	Intermec Ip Corp.	Keypad overlay membrane
US8114276B2 (en)	2007-10-24	2012-02-14	Baxter International Inc.	Personal hemodialysis system
US8501122B2 (en)	2009-12-08	2013-08-06	Affymetrix, Inc.	Manufacturing and processing polymer arrays

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8311018D0 (en) *	1983-04-22	1983-05-25	Amersham Int Plc	Detecting mutations in dna
US4683202A (en) *	1985-03-28	1987-07-28	Cetus Corporation	Process for amplifying nucleic acid sequences
AU606043B2 (en) *	1985-03-28	1991-01-31	F. Hoffmann-La Roche Ag	Detection of viruses by amplification and hybridization
US4683195A (en) *	1986-01-30	1987-07-28	Cetus Corporation	Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4794075A (en) *	1985-08-29	1988-12-27	Lifecodes Corporation	Method for locating and purifying DNA containing single base mismatches
US4800159A (en) *	1986-02-07	1989-01-24	Cetus Corporation	Process for amplifying, detecting, and/or cloning nucleic acid sequences
US4851331A (en) *	1986-05-16	1989-07-25	Allied Corporation	Method and kit for polynucleotide assay including primer-dependant DNA polymerase
US4889818A (en) *	1986-08-22	1989-12-26	Cetus Corporation	Purified thermostable enzyme
AU622104B2 (en) *	1987-03-11	1992-04-02	Sangtec Molecular Diagnostics Ab	Method of assaying of nucleic acids, a reagent combination and kit therefore

1989
- 1989-09-12 US US07/406,221 patent/US5196305A/en not_active Expired - Lifetime
1990
- 1990-08-31 CA CA002024459A patent/CA2024459A1/en not_active Abandoned
- 1990-09-06 DE DE69026449T patent/DE69026449T2/de not_active Expired - Lifetime
- 1990-09-06 AT AT90202372T patent/ATE136591T1/de not_active IP Right Cessation
- 1990-09-06 SG SG9601778A patent/SG96532A1/en unknown
- 1990-09-06 DK DK90202372.0T patent/DK0417842T3/da active
- 1990-09-06 EP EP90202372A patent/EP0417842B1/de not_active Expired - Lifetime
- 1990-09-11 JP JP2239166A patent/JPH07102139B2/ja not_active Expired - Lifetime
- 1990-09-11 KR KR1019900014614A patent/KR910006497A/ko not_active Withdrawn
- 1990-09-12 FI FI904494A patent/FI904494A7/fi not_active Application Discontinuation
- 1990-09-12 IE IE331090A patent/IE903310A1/en unknown

Also Published As

Publication number	Publication date
US5196305A (en)	1993-03-23
DK0417842T3 (da)	1996-05-06
IE903310A1 (en)	1991-04-10
FI904494A0 (fi)	1990-09-12
CA2024459A1 (en)	1991-03-13
SG96532A1 (en)	2003-06-16
DE69026449D1 (de)	1996-05-15
EP0417842A3 (en)	1991-08-28
EP0417842B1 (de)	1996-04-10
JPH0398586A (ja)	1991-04-24
JPH07102139B2 (ja)	1995-11-08
KR910006497A (ko)	1991-04-29
EP0417842A2 (de)	1991-03-20
FI904494A7 (fi)	1991-03-13
DE69026449T2 (de)	1996-09-19

Legal Events

Date	Code	Title	Description
2010-12-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE136591T1 (de)	1996-04-15	Verfahren zur diagnose und zur amplifikation, das das problem einer fehlpaarung zwischen primer und zielsequenz am 3'-ende des primers überwindet
ATE162222T1 (de)	1998-01-15	Verfahren zur extraktion, amplifikation und zum nachweis von nukleinsäuren aus vollblut
NZ218865A (en)	1989-05-29	Preparing samples for detecting of specific dna sequences
EP0465603A4 (en)	1992-12-09	Methods of detecting picornaviruses in biological fluids and tissues
ATE145248T1 (de)	1996-11-15	Schnellverfahren zum nachweis und/oder zur identifizierung einer einzelbase in einer nukleinsäuresequenz und seine verwendungen
DE69029726D1 (de)	1997-02-27	Festphasendiagnose von medizinischen konditionen
DE3751423D1 (de)	1995-08-24	Primers und Sonden zum Nachweis von Nukleinsäuren.
ATE121794T1 (de)	1995-05-15	Verfahren zum nachweis des karzinogenen menschlichen papillomavirus.
ATE142272T1 (de)	1996-09-15	Nukleinsäure-amplifikation unter verwendung eines einzelprimers
ATE188745T1 (de)	2000-01-15	Verfahren zur detektion einer nukleinsaeure mittels einer nukleinsaeuresonde, das ein spezifisches einfangen und eine detektion auf einmal erlaubt
DE69729122D1 (de)	2004-06-17	KüNSTLICHE FEHLHYBRIDISIERUNG
DE69840743D1 (de)	2009-05-28	Nukleinsäure-primer und -sonden zur detektion von hiv-1 und hiv-2
EP1757694A3 (de)	2008-02-27	Prostata-spezifisches Membranantigen
EP0787807A3 (de)	1998-04-01	Primers und Sondern zum Nachweis von Hepatitis C
ATE83505T1 (de)	1993-01-15	Verfahren zur amplifikation von nukleinsaeuresequenzen.
DE69635848D1 (de)	2006-04-27	Verfahren zum Nachweis von Ki-ras Mutationen
DE69737628D1 (de)	2007-05-31	Nukleinsäureprimer und -sonden zur detektion onkogener humaner papillomaviren
EP0382261A3 (de)	1992-08-05	DNS-Sonden gegen VNTR-Orte
ATE144557T1 (de)	1996-11-15	Nucleinsäure-proben und verfahren zum nachweis von giardia lamblia
ATE513061T1 (de)	2011-07-15	Diagnostisches verfahren und kit zur bestimmung des kell-blutgruppengenotyps