ATE418621T1 - Verfahren zur detektion allelspezifischer mutationen - Google Patents

Verfahren zur detektion allelspezifischer mutationen

Info

Publication number
ATE418621T1
ATE418621T1 AT04729459T AT04729459T ATE418621T1 AT E418621 T1 ATE418621 T1 AT E418621T1 AT 04729459 T AT04729459 T AT 04729459T AT 04729459 T AT04729459 T AT 04729459T AT E418621 T1 ATE418621 T1 AT E418621T1
Authority
AT
Austria
Prior art keywords
base
detecting
enzymatic detection
present
allel
Prior art date
Application number
AT04729459T
Other languages
English (en)
Inventor
Afshin Ahmadian
Joakim Lundeberg
Original Assignee
Afshin Ahmadian
Joakim Lundeberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Afshin Ahmadian, Joakim Lundeberg filed Critical Afshin Ahmadian
Application granted granted Critical
Publication of ATE418621T1 publication Critical patent/ATE418621T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04729459T 2003-04-24 2004-04-26 Verfahren zur detektion allelspezifischer mutationen ATE418621T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0309350 2003-04-24

Publications (1)

Publication Number Publication Date
ATE418621T1 true ATE418621T1 (de) 2009-01-15

Family

ID=33306523

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04729459T ATE418621T1 (de) 2003-04-24 2004-04-26 Verfahren zur detektion allelspezifischer mutationen

Country Status (6)

Country Link
US (1) US7262032B2 (de)
EP (1) EP1620568B1 (de)
AT (1) ATE418621T1 (de)
DE (1) DE602004018631D1 (de)
DK (1) DK1620568T3 (de)
WO (1) WO2004094666A1 (de)

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US20120141986A1 (en) * 2007-03-27 2012-06-07 Kenneth Kuhn Multivalent substrate elements for detection of nucleic acid sequences
WO2011112947A1 (en) * 2010-03-12 2011-09-15 Cenetron Diagnostics Llc Methods and compositions comprising nucleic acid polymerization enhancers
CN102892901B (zh) * 2010-03-24 2015-11-25 凸版印刷株式会社 利用竞争性引物的目标碱基序列的检测方法
US10787701B2 (en) * 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
JP6069224B2 (ja) * 2011-01-31 2017-02-01 アプライズ バイオ, インコーポレイテッド 細胞において複数のエピトープを同定する方法
US9074204B2 (en) * 2011-05-20 2015-07-07 Fluidigm Corporation Nucleic acid encoding reactions
CN108603224B (zh) 2015-12-16 2022-06-28 富鲁达公司 高水平多路复用扩增
US20170327876A1 (en) * 2016-05-16 2017-11-16 Nanostring Technologies, Inc. Methods for detecting target nucleic acids in a sample
KR102476709B1 (ko) 2016-11-21 2022-12-09 나노스트링 테크놀로지스, 인크. 화학적 조성물 및 이것을 사용하는 방법
JP7525402B2 (ja) 2018-05-14 2024-07-30 ナノストリング テクノロジーズ,インコーポレイティド 化学的組成物とそれを利用する方法

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CA2013317A1 (en) 1989-04-17 1990-10-17 Fred T. Oakes Diagnostic kit, primer composition and their use for replication or detection of nucleic acids
US5302509A (en) * 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
US5196305A (en) 1989-09-12 1993-03-23 Eastman Kodak Company Diagnostic and amplification methods using primers having thymine at 3' end to overcome primer-target mismatch at the 3' end
GB9208733D0 (en) * 1992-04-22 1992-06-10 Medical Res Council Dna sequencing method
US5338671A (en) * 1992-10-07 1994-08-16 Eastman Kodak Company DNA amplification with thermostable DNA polymerase and polymerase inhibiting antibody
US5567300A (en) * 1994-09-02 1996-10-22 Ibm Corporation Electrochemical metal removal technique for planarization of surfaces
US5565340A (en) * 1995-01-27 1996-10-15 Clontech Laboratories, Inc. Method for suppressing DNA fragment amplification during PCR
EP0745688B1 (de) 1995-06-01 2007-02-14 Roche Diagnostics GmbH Die Verwendung der 3'-wesentlichen Bearbeitungswirksamkeit von DNS-Polymerase
WO1996041010A1 (en) * 1995-06-07 1996-12-19 Nexstar Pharmaceuticals, Inc. Nucleic acid ligands that bind to and inhibit dna polymerases
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US6183998B1 (en) * 1998-05-29 2001-02-06 Qiagen Gmbh Max-Volmer-Strasse 4 Method for reversible modification of thermostable enzymes
US6176992B1 (en) * 1998-11-03 2001-01-23 Nutool, Inc. Method and apparatus for electro-chemical mechanical deposition
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US6610190B2 (en) * 2000-11-03 2003-08-26 Nutool, Inc. Method and apparatus for electrodeposition of uniform film with minimal edge exclusion on substrate
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US6848970B2 (en) * 2002-09-16 2005-02-01 Applied Materials, Inc. Process control in electrochemically assisted planarization
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US7220166B2 (en) * 2000-08-30 2007-05-22 Micron Technology, Inc. Methods and apparatus for electromechanically and/or electrochemically-mechanically removing conductive material from a microelectronic substrate
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WO2002068684A2 (en) * 2001-02-23 2002-09-06 Pyrosequencing Ab Allele-specific primer extension assay

Also Published As

Publication number Publication date
DK1620568T3 (da) 2009-03-30
US20060088872A1 (en) 2006-04-27
DE602004018631D1 (de) 2009-02-05
EP1620568B1 (de) 2008-12-24
EP1620568A1 (de) 2006-02-01
US7262032B2 (en) 2007-08-28
WO2004094666A1 (en) 2004-11-04

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