ATE418621T1 - Verfahren zur detektion allelspezifischer mutationen - Google Patents
Verfahren zur detektion allelspezifischer mutationenInfo
- Publication number
- ATE418621T1 ATE418621T1 AT04729459T AT04729459T ATE418621T1 AT E418621 T1 ATE418621 T1 AT E418621T1 AT 04729459 T AT04729459 T AT 04729459T AT 04729459 T AT04729459 T AT 04729459T AT E418621 T1 ATE418621 T1 AT E418621T1
- Authority
- AT
- Austria
- Prior art keywords
- base
- detecting
- enzymatic detection
- present
- allel
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000035772 mutation Effects 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 abstract 5
- 238000001514 detection method Methods 0.000 abstract 4
- 230000002255 enzymatic effect Effects 0.000 abstract 4
- 102000003960 Ligases Human genes 0.000 abstract 1
- 108090000364 Ligases Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000007791 liquid phase Substances 0.000 abstract 1
- 238000002493 microarray Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 238000011895 specific detection Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0309350 | 2003-04-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE418621T1 true ATE418621T1 (de) | 2009-01-15 |
Family
ID=33306523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04729459T ATE418621T1 (de) | 2003-04-24 | 2004-04-26 | Verfahren zur detektion allelspezifischer mutationen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7262032B2 (de) |
| EP (1) | EP1620568B1 (de) |
| AT (1) | ATE418621T1 (de) |
| DE (1) | DE602004018631D1 (de) |
| DK (1) | DK1620568T3 (de) |
| WO (1) | WO2004094666A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7833716B2 (en) | 2006-06-06 | 2010-11-16 | Gen-Probe Incorporated | Tagged oligonucleotides and their use in nucleic acid amplification methods |
| GB0702557D0 (en) * | 2007-02-09 | 2007-03-21 | Health Prot Agency | Detection of human papillomavirus |
| US20120141986A1 (en) * | 2007-03-27 | 2012-06-07 | Kenneth Kuhn | Multivalent substrate elements for detection of nucleic acid sequences |
| WO2011112947A1 (en) * | 2010-03-12 | 2011-09-15 | Cenetron Diagnostics Llc | Methods and compositions comprising nucleic acid polymerization enhancers |
| JP5842811B2 (ja) * | 2010-03-24 | 2016-01-13 | 凸版印刷株式会社 | 競合プライマーによる標的塩基配列の検出方法 |
| US10787701B2 (en) * | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| WO2012106385A2 (en) * | 2011-01-31 | 2012-08-09 | Apprise Bio, Inc. | Methods of identifying multiple epitopes in cells |
| SG10201605049QA (en) * | 2011-05-20 | 2016-07-28 | Fluidigm Corp | Nucleic acid encoding reactions |
| CN108603224B (zh) | 2015-12-16 | 2022-06-28 | 富鲁达公司 | 高水平多路复用扩增 |
| CN116200462B (zh) * | 2016-05-16 | 2025-10-03 | 布鲁克空间生物学公司 | 用于检测样品中目标核酸的方法 |
| EP4556575A3 (de) | 2016-11-21 | 2025-10-08 | Bruker Spatial Biology, Inc. | Verfahren zur sequenzierung von nukleinsäuren |
| EP3794146B1 (de) | 2018-05-14 | 2025-12-10 | Bruker Spatial Biology, Inc. | Verfahren zur erkennung einer zuvor bestimmten nukleotidesequenz |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO155316C (no) | 1982-04-23 | 1987-03-11 | Sintef | Fremgangsmaate for fremstilling av magnetiske polymerpartikler. |
| CA2013317A1 (en) | 1989-04-17 | 1990-10-17 | Fred T. Oakes | Diagnostic kit, primer composition and their use for replication or detection of nucleic acids |
| US5302509A (en) | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
| US5196305A (en) | 1989-09-12 | 1993-03-23 | Eastman Kodak Company | Diagnostic and amplification methods using primers having thymine at 3' end to overcome primer-target mismatch at the 3' end |
| GB9208733D0 (en) | 1992-04-22 | 1992-06-10 | Medical Res Council | Dna sequencing method |
| US5338671A (en) | 1992-10-07 | 1994-08-16 | Eastman Kodak Company | DNA amplification with thermostable DNA polymerase and polymerase inhibiting antibody |
| US5567300A (en) * | 1994-09-02 | 1996-10-22 | Ibm Corporation | Electrochemical metal removal technique for planarization of surfaces |
| US5565340A (en) | 1995-01-27 | 1996-10-15 | Clontech Laboratories, Inc. | Method for suppressing DNA fragment amplification during PCR |
| EP0745688B1 (de) | 1995-06-01 | 2007-02-14 | Roche Diagnostics GmbH | Die Verwendung der 3'-wesentlichen Bearbeitungswirksamkeit von DNS-Polymerase |
| US6020130A (en) * | 1995-06-07 | 2000-02-01 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands that bind to and inhibit DNA polymerases |
| US6190865B1 (en) * | 1995-09-27 | 2001-02-20 | Epicentre Technologies Corporation | Method for characterizing nucleic acid molecules |
| US5862605A (en) * | 1996-05-24 | 1999-01-26 | Ebara Corporation | Vaporizer apparatus |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US6485944B1 (en) | 1997-10-10 | 2002-11-26 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US6183998B1 (en) * | 1998-05-29 | 2001-02-06 | Qiagen Gmbh Max-Volmer-Strasse 4 | Method for reversible modification of thermostable enzymes |
| US6176992B1 (en) * | 1998-11-03 | 2001-01-23 | Nutool, Inc. | Method and apparatus for electro-chemical mechanical deposition |
| US6497800B1 (en) * | 2000-03-17 | 2002-12-24 | Nutool Inc. | Device providing electrical contact to the surface of a semiconductor workpiece during metal plating |
| US6902659B2 (en) * | 1998-12-01 | 2005-06-07 | Asm Nutool, Inc. | Method and apparatus for electro-chemical mechanical deposition |
| US6534116B2 (en) * | 2000-08-10 | 2003-03-18 | Nutool, Inc. | Plating method and apparatus that creates a differential between additive disposed on a top surface and a cavity surface of a workpiece using an external influence |
| US6251235B1 (en) * | 1999-03-30 | 2001-06-26 | Nutool, Inc. | Apparatus for forming an electrical contact with a semiconductor substrate |
| US6610190B2 (en) * | 2000-11-03 | 2003-08-26 | Nutool, Inc. | Method and apparatus for electrodeposition of uniform film with minimal edge exclusion on substrate |
| GB9901475D0 (en) | 1999-01-22 | 1999-03-17 | Pyrosequencing Ab | A method of DNA sequencing |
| JP3422731B2 (ja) * | 1999-07-23 | 2003-06-30 | 理化学研究所 | Ｅｌｉｄセンタレス研削装置 |
| US6653226B1 (en) * | 2001-01-09 | 2003-11-25 | Novellus Systems, Inc. | Method for electrochemical planarization of metal surfaces |
| US6848970B2 (en) * | 2002-09-16 | 2005-02-01 | Applied Materials, Inc. | Process control in electrochemically assisted planarization |
| NO20003669L (no) | 2000-07-18 | 2002-01-21 | Quick Anchor As | Festeinnretning i treverk |
| US7220166B2 (en) * | 2000-08-30 | 2007-05-22 | Micron Technology, Inc. | Methods and apparatus for electromechanically and/or electrochemically-mechanically removing conductive material from a microelectronic substrate |
| US6696358B2 (en) * | 2001-01-23 | 2004-02-24 | Honeywell International Inc. | Viscous protective overlayers for planarization of integrated circuits |
| GB0102568D0 (en) | 2001-02-01 | 2001-03-21 | Magnetic Biosolutions Sweden A | Method |
| WO2002068684A2 (en) * | 2001-02-23 | 2002-09-06 | Pyrosequencing Ab | Allele-specific primer extension assay |
-
2004
- 2004-04-26 WO PCT/GB2004/001766 patent/WO2004094666A1/en not_active Ceased
- 2004-04-26 EP EP04729459A patent/EP1620568B1/de not_active Expired - Lifetime
- 2004-04-26 DK DK04729459T patent/DK1620568T3/da active
- 2004-04-26 DE DE602004018631T patent/DE602004018631D1/de not_active Expired - Lifetime
- 2004-04-26 AT AT04729459T patent/ATE418621T1/de not_active IP Right Cessation
-
2005
- 2005-10-21 US US11/256,694 patent/US7262032B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004094666A1 (en) | 2004-11-04 |
| EP1620568B1 (de) | 2008-12-24 |
| DE602004018631D1 (de) | 2009-02-05 |
| US20060088872A1 (en) | 2006-04-27 |
| US7262032B2 (en) | 2007-08-28 |
| EP1620568A1 (de) | 2006-02-01 |
| DK1620568T3 (da) | 2009-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |