ATE136785T1 - Verfahren zum herstellen hartgelatinekapseln, die chinesische kräuterextrakte enthalten - Google Patents

Verfahren zum herstellen hartgelatinekapseln, die chinesische kräuterextrakte enthalten

Info

Publication number: ATE136785T1
Authority: AT; Austria
Prior art keywords: kampo medicine; hard capsules; kampo; medicine; chinese herbal
Prior art date: 1991-09-05

Application number

AT92115192T

Other languages

English (en)

Inventor

Toshihiro Uchida

Shin Ichiro Konishi

Takayoshi Kimura

Original Assignee

Tsumura & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-05

Filing date

1992-09-04

Publication date

1996-05-15

1992-09-04 Application filed by Tsumura & Co filed Critical Tsumura & Co

1996-05-15 Application granted granted Critical

1996-05-15 Publication of ATE136785T1 publication Critical patent/ATE136785T1/de

Links

239000007903 gelatin capsule Substances 0.000 title 1
239000012676 herbal extract Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
239000003814 drug Substances 0.000 abstract 8
239000007902 hard capsule Substances 0.000 abstract 5
239000000284 extract Substances 0.000 abstract 4
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 4
238000004090 dissolution Methods 0.000 abstract 2
235000019359 magnesium stearate Nutrition 0.000 abstract 2
239000000843 powder Substances 0.000 abstract 2
-1 Anchu-san Substances 0.000 abstract 1
108010010803 Gelatin Proteins 0.000 abstract 1
239000010313 San'o-shashin-to Substances 0.000 abstract 1
FXNFHKRTJBSTCS-UHFFFAOYSA-N baicalein Chemical compound C=1C(=O)C=2C(O)=C(O)C(O)=CC=2OC=1C1=CC=CC=C1 FXNFHKRTJBSTCS-UHFFFAOYSA-N 0.000 abstract 1
239000009495 byakko-ka-ninjin-to Substances 0.000 abstract 1
229920000159 gelatin Polymers 0.000 abstract 1
239000008273 gelatin Substances 0.000 abstract 1
235000019322 gelatine Nutrition 0.000 abstract 1
235000011852 gelatine desserts Nutrition 0.000 abstract 1
239000009506 keishibukuryogan Substances 0.000 abstract 1
239000009989 mao-bushi-saishin-to Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000009441 oren gedoku to Substances 0.000 abstract 1
230000004526 pharmaceutical effect Effects 0.000 abstract 1
239000008535 sairei-to Substances 0.000 abstract 1
239000009181 shakuyaku-kanzoh-toh Substances 0.000 abstract 1
239000008485 shosaiko-to Substances 0.000 abstract 1
239000008423 tao-shang-tsao Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

Health & Medical Sciences (AREA)
Natural Medicines & Medicinal Plants (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Alternative & Traditional Medicine (AREA)
Mycology (AREA)
Microbiology (AREA)
Medical Informatics (AREA)
Botany (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Inorganic Chemistry (AREA)
Medicinal Preparation (AREA)
Medicines Containing Plant Substances (AREA)

AT92115192T 1991-09-05 1992-09-04 Verfahren zum herstellen hartgelatinekapseln, die chinesische kräuterextrakte enthalten ATE136785T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP25274791		1991-09-05

Publications (1)

Publication Number	Publication Date
ATE136785T1 true ATE136785T1 (de)	1996-05-15

Family

ID=17241721

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92115192T ATE136785T1 (de)	1991-09-05	1992-09-04	Verfahren zum herstellen hartgelatinekapseln, die chinesische kräuterextrakte enthalten

Country Status (5)

Country	Link
US (1)	US5318798A (de)
EP (1)	EP0530833B1 (de)
AT (1)	ATE136785T1 (de)
DE (1)	DE69209942T2 (de)
ES (1)	ES2088523T3 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4065321B2 (ja) *	1995-03-29	2008-03-26	塩野義製薬株式会社	水分活性を調節したゼラチンカプセル剤
KR100195886B1 (ko) *	1996-11-01	1999-06-15	김상조	당뇨병 치료용 의약조성물
DE19758100B4 (de) *	1997-12-18	2006-05-04	Lichtwer Pharma Ag	Verfahren zum Herstellen von Pflanzenextrakt enthaltenden pharmazeutischen Formulierungen
AR020343A1 (es) *	1998-11-24	2002-05-08	Steigerwald Arzlneimittelwerk	Metodo para producir farmacos que contienen extractos de plantas en una forma solida de aplicacion.
US20010024664A1 (en) *	1999-03-19	2001-09-27	Obukowicz Mark G.	Selective COX-2 inhibition from edible plant extracts
US6238696B1 (en) *	2000-01-07	2001-05-29	Gaia Herbs, Inc.	Process for providing herbal medicants in cellulose derivative capsules
DE10112167C2 (de)	2001-03-12	2003-02-13	Bionorica Ag	Verfahren zur schonenden Gewinnung von Trockenextrakten
DE10144108A1 (de)	2001-09-03	2003-04-30	Steigerwald Arzneimittelwerk	Verfahren zur Herstellung von Tabletten aus pflanzlichen Extrakten
US20040062823A1 (en) *	2001-12-13	2004-04-01	Obukowicz Mark G.	Selective cox-2 inhibition from non-edible plant extracts
US20040126438A1 (en) *	2001-12-13	2004-07-01	Obukowicz Mark G.	Selective cox-2 inhibition from plant extracts
US7258877B2 (en) *	2001-12-21	2007-08-21	Sunten Phytotech Co., Ltd.	Herbal pharmaceutical composition for treatment of cardiovascular disease
TWI275397B (en) *	2001-12-21	2007-03-11	Sun Ten Pharmaceutical Co Ltd	Herbal composition, use thereof in protection of endothelial cell and in anti-inflammation, and preparation method thereof
US7326427B2 (en) *	2002-07-12	2008-02-05	Tsumura & Co.	Tablet composition containing Kampo medicinal extract and its manufacturing process
US7051606B2 (en) *	2004-01-30	2006-05-30	Andrx Labs Llc	Dosage form holder device and methods for immersion testing
US20090098228A1 (en) *	2007-10-10	2009-04-16	Tsumura & Co.	Agent and method for improvement of impairment of learning and memory
CN102600273A (zh) *	2011-08-25	2012-07-25	浙江省中药研究所有限公司	一种新鲜栀子的加工方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2130113C3 (de) *	1970-06-22	1980-07-03	Scherico Ltd., Luzern (Schweiz)	Gentamicin B, Gentamicin B1 und Gentamicin X, Verfahren zu deren Gewinnung und diese Gentamicine enthaltende pharmazeutische Zubereitungen
US3909444A (en) *	1971-08-05	1975-09-30	Ncr Co	Microcapsule
US3780065A (en) *	1972-08-10	1973-12-18	Smithkline Corp	Phenylvulpinic acid derivatives
JPS5115094B2 (de) *	1972-11-01	1976-05-14
GB8413191D0 (en) *	1984-05-23	1984-06-27	Beecham Group Plc	Pharmaceutical composition
JPS61205272A (ja) *	1985-03-08	1986-09-11	Tsumura Juntendo Inc	新規なタンニン
ATE87204T1 (de) *	1987-12-10	1993-04-15	Tsumura & Co	Anti-retrovirales arzneimittel.
JP3179522B2 (ja) *	1991-06-26	2001-06-25	宏樹宮松	染色繊維製品およびその製造法

1992
- 1992-09-04 EP EP92115192A patent/EP0530833B1/de not_active Expired - Lifetime
- 1992-09-04 ES ES92115192T patent/ES2088523T3/es not_active Expired - Lifetime
- 1992-09-04 AT AT92115192T patent/ATE136785T1/de not_active IP Right Cessation
- 1992-09-04 DE DE69209942T patent/DE69209942T2/de not_active Expired - Fee Related
- 1992-09-08 US US07/941,800 patent/US5318798A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0530833A1 (de)	1993-03-10
ES2088523T3 (es)	1996-08-16
US5318798A (en)	1994-06-07
DE69209942T2 (de)	1996-09-05
DE69209942D1 (de)	1996-05-23
EP0530833B1 (de)	1996-04-17

Legal Events

Date	Code	Title	Description
1996-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE136785T1 (de)	1996-05-15	Verfahren zum herstellen hartgelatinekapseln, die chinesische kräuterextrakte enthalten
KR840000228A (ko)	1984-02-18	조제성 혼합물에 있어서 건성분말의 제조방법
GR1000614B (el)	1992-08-31	Προηγμενη μεθοδος καψουλοποιησεως και προιοντα εξ αυτης.
CA2052392A1 (en)	1992-03-29	Extract from ginkgo biloba leaves, in particular for intravenous injection or infusion, a method of preparation of the extract and ampoule preparations containing the extract
GR3035045T3 (en)	2001-03-30	Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof.
AU578577B2 (en)	1988-10-27	Devices for the controlled release of active substances, as well as process for the preparation thereof
DE69518006D1 (de)	2000-08-17	Verfahren zur einkapselung von tabletten in eine kapsel und feststoff-dosierungsformen erhaltbar durch dieses verfahren
KR920017656A (ko)	1992-10-21	저 용량 건조 약학 제제
EP0413828A4 (en)	1991-10-30	Solid preparation of activated vitamin d 3? having improved stability
ATA318788A (de)	1993-04-15	Neue derivate der 17beta-oh 19-nor-steroide, die an stelle 17alpha substituiert sind, ihr herstellungsverfahren, ihre anwendung als medikamente und pharmazeutische erzeugnisse, in denen sie enthalten sind
DK0397247T3 (da)	1995-11-06	Fedtsammensætning til chokoladekonfekture
BG93579A (bg)	1993-12-24	Магнезиев хидроокис във вид на фин прах и метод за неговото получаване
KR910005879A (ko)	1991-04-27	신규 항암작용을 가지는 약학적 제제 및 제조방법
DE2426812A1 (de)	1976-01-02	Verfahren zur herstellung von granulaten
YU67492A (sr)	1996-01-09	Postupak za dobijanje farmaceutskog sredstva
ES412146A1 (es)	1976-01-01	Procedimiento de obtencion de composiciones para reducir elhabito del tabaco.
Kwon et al.	1994	Characterization of slip of powder/binder mixtures and its effects in PIM filling process analysis
Strijbos et al.	1977	Mechanical properties of a ferrite powder and its granulate
SU1586243A1 (ru)	1995-04-10	Сплав на основе алюминия
KR930021229A (ko)	1993-11-22	피부 자극용 한약 및 자석 함유물
JPS57108228A (en)	1982-07-06	Composite magnetic material having compound magnetization curve by powder metallurgy
KR880012206A (ko)	1988-11-26	구강질환 치료 조성물
Poole	1987	Activated Sintering of Metallic Powders
Rasheed et al.	1997	Fetal toxicity of Anastatica hierochuntica L. in mice
KR960003620A (ko)	1996-02-23	생약재로부터 추출된 항산화성 물질 및 이의 제조방법