ATE137799T1 - Lösliches molekül, das mit icam-1 verwandt, aber davon verschieden ist - Google Patents

Lösliches molekül, das mit icam-1 verwandt, aber davon verschieden ist

Info

Publication number
ATE137799T1
ATE137799T1 AT90100557T AT90100557T ATE137799T1 AT E137799 T1 ATE137799 T1 AT E137799T1 AT 90100557 T AT90100557 T AT 90100557T AT 90100557 T AT90100557 T AT 90100557T AT E137799 T1 ATE137799 T1 AT E137799T1
Authority
AT
Austria
Prior art keywords
sicam
icam
purified
different
relates
Prior art date
Application number
AT90100557T
Other languages
English (en)
Inventor
Jeffrey Greve
Alan Mcclelland
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26972210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE137799(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/301,192 external-priority patent/US5235049A/en
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE137799T1 publication Critical patent/ATE137799T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Bipolar Transistors (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90100557T 1989-01-24 1990-01-12 Lösliches molekül, das mit icam-1 verwandt, aber davon verschieden ist ATE137799T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/301,192 US5235049A (en) 1989-01-24 1989-01-24 Nucleic acid sequences encoding a soluble molecule (SICAM-1) related to but distinct from ICAM-1
US44595189A 1989-12-13 1989-12-13

Publications (1)

Publication Number Publication Date
ATE137799T1 true ATE137799T1 (de) 1996-05-15

Family

ID=26972210

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90100557T ATE137799T1 (de) 1989-01-24 1990-01-12 Lösliches molekül, das mit icam-1 verwandt, aber davon verschieden ist

Country Status (15)

Country Link
EP (1) EP0379904B1 (de)
JP (1) JP3080631B2 (de)
KR (1) KR100202435B1 (de)
AT (1) ATE137799T1 (de)
AU (1) AU641134B2 (de)
DE (1) DE69026844T2 (de)
DK (1) DK0379904T3 (de)
ES (1) ES2087091T3 (de)
FI (1) FI100601B (de)
GR (1) GR3020481T3 (de)
IE (1) IE74144B1 (de)
IL (1) IL93119A (de)
NO (1) NO900155L (de)
NZ (1) NZ232203A (de)
PT (1) PT92920B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
EP0362531B1 (de) 1988-09-01 1999-11-10 Bayer Corporation Menschliches Rhinovirusrezeptorprotein, das die Virusinfektionsanfälligkeit hemmt
US5776775A (en) * 1989-02-21 1998-07-07 Dana-Farber Cancer Institute Anti-LAM 1-3 antibody and hybridoma
US6797270B1 (en) 1989-03-16 2004-09-28 Center For Blood Research, Inc. Functional derivatives of the intercellular adhesion molecule ICAM-1 in anti-viral therapy
DK0745852T3 (da) * 1989-03-16 2002-10-14 Blood Res Center Anvendelse af funktionelle derivater af intercellulær adhæsion-molekylet ICAM-1 i antiviral terapi
HU217792B (hu) * 1989-03-16 2000-04-28 Dana Farber Cancer Institute Eljárás intercelluláris adhéziós molekula (ICAM-1) oldható származékai és ezeket tartalmazó gyógyszerkészítmények előállítására
WO1991018011A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of cell adhesion using intercellular adhesion molecule-1-like peptides and/or analogues thereof
WO1991018010A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
ATE184049T1 (de) * 1990-07-20 1999-09-15 Bayer Ag Multimere formen des menschlichen rhinovirus- rezeptorproteins
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5686582A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US5686581A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
AU710965B2 (en) * 1992-06-22 1999-09-30 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
CA2140933A1 (en) * 1992-08-21 1994-02-22 Paula M. Jardieu Method for treating an lfa-1 mediated disorder
FR2710778B1 (fr) * 1993-09-29 1995-12-01 Framatome Sa Grappe de commande pour réacteur nucléaire et réacteur en faisant application.
DE4335273A1 (de) * 1993-10-15 1995-04-20 Univ Ludwigs Albert Peptide zur Tumortherapie
US20020081294A1 (en) 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
US5914112A (en) * 1996-01-23 1999-06-22 Genentech, Inc. Anti-CD18 antibodies in stroke
AU735917B2 (en) * 1997-10-02 2001-07-19 Icos Corporation ICAM-4 and diagnostic uses thereof
FR2788161B1 (fr) * 1998-12-30 2001-03-23 Framatome Sa Crayon absorbant pour grappe de commande de reacteur nucleaire
US6582698B1 (en) 1999-03-19 2003-06-24 Genentech, Inc. Treatment method
WO2000056363A1 (en) 1999-03-19 2000-09-28 Genentech, Inc. Treatment of lfa-1 associated disorders with increasing doses of lfa-1 antagonist
US8741557B2 (en) 2003-02-14 2014-06-03 Beth Israel Deaconess Medical Center, Inc. Predicting graft rejection
JP4671323B2 (ja) * 2004-04-28 2011-04-13 大日本印刷株式会社 ディスプレイ装置
EP1756163A2 (de) 2004-06-09 2007-02-28 Genentech, Inc. Verfahren zur behandlung von granuloma annulare oder sarkoid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE128727T1 (de) * 1987-05-04 1995-10-15 Dana Farber Cancer Inst Inc Interzellulare adhäsions-moleküle und deren bindungsliganden.
ATE114972T1 (de) * 1987-11-02 1994-12-15 Baylor College Medicine Verwendung von icam-1 oder ihre funktionelle derivate zur behandlung unspezifischer entzündungen.
CA1341055C (en) * 1987-12-08 2000-07-18 Alan Mcclelland Transfectant cell lines which express the major human rhinovirus receptor
EP0362531B1 (de) * 1988-09-01 1999-11-10 Bayer Corporation Menschliches Rhinovirusrezeptorprotein, das die Virusinfektionsanfälligkeit hemmt
AU636230B2 (en) * 1990-10-24 1993-04-22 Dolores Y. Beaupied Garment to hold an ostomy appliance

Also Published As

Publication number Publication date
NZ232203A (en) 1992-10-28
FI900331A0 (fi) 1990-01-22
KR900011895A (ko) 1990-08-02
IL93119A (en) 1999-07-14
IE900257L (en) 1990-07-24
KR100202435B1 (ko) 1999-06-15
AU4876790A (en) 1990-08-02
NO900155D0 (no) 1990-01-11
IE74144B1 (en) 1997-07-02
DK0379904T3 (da) 1996-09-16
PT92920A (pt) 1990-07-31
EP0379904A1 (de) 1990-08-01
GR3020481T3 (en) 1996-10-31
NO900155L (no) 1990-07-25
DE69026844D1 (de) 1996-06-13
EP0379904B1 (de) 1996-05-08
DE69026844T2 (de) 1996-09-12
JP3080631B2 (ja) 2000-08-28
PT92920B (pt) 1995-12-29
ES2087091T3 (es) 1996-07-16
JPH0381296A (ja) 1991-04-05
IL93119A0 (en) 1990-11-05
FI100601B (fi) 1998-01-15
AU641134B2 (en) 1993-09-16

Similar Documents

Publication Publication Date Title
DE69026844D1 (de) Lösliches Molekül, das mit ICAM-1 verwandt, aber davon verschieden ist
CA2008368A1 (en) Soluble molecule related to but distinct from icam-1
MX9702932A (es) L-ribofuranosilnucleosidos.
IL93508A0 (en) Novel benzimidazole and azabenimidazole derivatives,their methods of preparation,synthesis intermediates and pharmaceutical compositions in which they are present and which are useful especially for the treatment of cardiovascular diseases and duodenal ulcers
DE69330372D1 (de) ZUSAMMENSETZUNGEN UND VERFAHREN FüR DIE BEHANDLUNG VON MIT HEPATITIS C VIREN ASSOZIIERTEN KRANKHEITEN
DE69930739D1 (de) Transdermale verwendung von sekretin zur behandlung von autismus
EP0727212A3 (de) Substituierte Phenylpyrimidine Derivate, für die Behandlung oder Prevention von ZNS-Erkrankungen
KR950700333A (ko) 개량된 알파 인터페론 조성물 및 인간 말초혈 백혈구로부터의 제조 방법(improved alpha interferon composition and method for its production from human peripheral blood leukocytes)
DE69425890D1 (de) Verfahren zur behandlung von kaposi-sarcoma mit antisense-oligonukleotide
ATE105482T1 (de) Behandlung von krebs mit somatostatin und mit analogen davon.
ATE98376T1 (de) Synthetische htlv-iii-peptid-zusammensetzungen und ihre verwendung.
DE69736184D1 (de) Antagonisten von g protein-gekoppelten rezeptoren
ATE189527T1 (de) Bestimmung von peptidmotiven auf mhc-molekülen
FR2738151B1 (fr) Antagonistes de l'activite oncogenique de la proteine mdm2, et leur utilisation dans le traitement des cancers
DE68923048D1 (de) Alpha-Subeinheit des LFA-1-Leukocyt-Adhäsions-Rezeptors.
DK0701440T3 (da) Tri(platin)komplekser
ATE325803T1 (de) Glycokonjugate, glycoaminosäure, deren zwischenprodukte, und ihre verwendung
FI913818A0 (fi) Nytt trombolytiskt aemne.
HUP0003174A2 (hu) 20(S)-Kamptotecin glikokonjugátumai, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények
ATE174798T1 (de) Die herstellung von zusammensetzungen zur behandlung von krankheiten der zellproliferation
MX9702926A (es) L-eritrosilnucleosidos.
BG102707A (bg) Нови триазолопурини, метод за тяхното получаване и тяхното приложение като лекарствени средства
NO983177L (no) Anvendelse av 1-enantiomeren av centkroman til fremstilling av et farmasaytisk preparat for behandling eller profylakse av brystkreft
DE3789562D1 (de) Verfahren zur Behandlung von Karbid-Metallverbundkörpern im Bezug auf ihr Gefüge und ihre Zusammensetzung.
DE69128254D1 (de) Antihypertensive benzopyran-derivate

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee