ATE137975T1 - Amylin zur behandlung von knochenleiden - Google Patents

Amylin zur behandlung von knochenleiden

Info

Publication number: ATE137975T1
Authority: AT; Austria
Prior art keywords: amylin; bone; treatment; disorders; variants
Prior art date: 1989-07-08

Application number

AT90307471T

Other languages

English (en)

Inventor

Iain Macintyre

Original Assignee

Amylin Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-08

Filing date

1990-07-09

Publication date

1996-06-15

1990-07-09 Application filed by Amylin Pharmaceuticals Inc filed Critical Amylin Pharmaceuticals Inc

1996-06-15 Application granted granted Critical

1996-06-15 Publication of ATE137975T1 publication Critical patent/ATE137975T1/de

Links

102000036770 Islet Amyloid Polypeptide Human genes 0.000 title abstract 8
108010041872 Islet Amyloid Polypeptide Proteins 0.000 title abstract 8
208000020084 Bone disease Diseases 0.000 title abstract 2
210000000988 bone and bone Anatomy 0.000 abstract 2
239000012634 fragment Substances 0.000 abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
229940127438 Amylin Agonists Drugs 0.000 abstract 1
206010065687 Bone loss Diseases 0.000 abstract 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
208000017701 Endocrine disease Diseases 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
208000010191 Osteitis Deformans Diseases 0.000 abstract 1
208000001132 Osteoporosis Diseases 0.000 abstract 1
208000027868 Paget disease Diseases 0.000 abstract 1
108010033276 Peptide Fragments Proteins 0.000 abstract 1
102000007079 Peptide Fragments Human genes 0.000 abstract 1
229940100389 Sulfonylurea Drugs 0.000 abstract 1
239000002269 analeptic agent Substances 0.000 abstract 1
206010003246 arthritis Diseases 0.000 abstract 1
230000001363 autoimmune Effects 0.000 abstract 1
229910052791 calcium Inorganic materials 0.000 abstract 1
239000011575 calcium Substances 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
229940011871 estrogen Drugs 0.000 abstract 1
239000000262 estrogen Substances 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
230000001184 hypocalcaemic effect Effects 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
230000036210 malignancy Effects 0.000 abstract 1
230000003211 malignant effect Effects 0.000 abstract 1
208000027202 mammary Paget disease Diseases 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/225—Calcitonin gene related peptide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Zoology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Nutrition Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Hematology (AREA)
Obesity (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Materials For Medical Uses (AREA)

AT90307471T 1989-07-08 1990-07-09 Amylin zur behandlung von knochenleiden ATE137975T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898915712A GB8915712D0 (en)	1989-07-08	1989-07-08	Medical treatment

Publications (1)

Publication Number	Publication Date
ATE137975T1 true ATE137975T1 (de)	1996-06-15

Family

ID=10659773

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90307471T ATE137975T1 (de)	1989-07-08	1990-07-09	Amylin zur behandlung von knochenleiden

Country Status (12)

Country	Link
EP (1)	EP0408284B1 (de)
JP (1)	JPH04500691A (de)
AT (1)	ATE137975T1 (de)
CA (1)	CA2020752C (de)
DE (1)	DE69026986T2 (de)
DK (2)	DK0408284T3 (de)
ES (1)	ES2088971T3 (de)
GB (1)	GB8915712D0 (de)
GR (1)	GR3020680T3 (de)
IE (1)	IE62625B1 (de)
SG (1)	SG46382A1 (de)
WO (1)	WO1991000710A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG49239A1 (en) *	1991-05-24	1998-05-18	Amylin Pharmaceuticals Inc	Amylin and possibly insulin containing composition for the treatment of aneroxia and related states
SG44838A1 (en) *	1991-05-24	1997-12-19	Amylin Pharmaceuticals Inc	Insulin and amylin containing composition for the treatment of insulin deficient mammals
US6001884A (en) *	1991-08-23	1999-12-14	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
US5763569A (en) *	1991-08-23	1998-06-09	The Brigham And Women's Hospital, Inc	Calcium receptor-active molecules
US6313146B1 (en)	1991-08-23	2001-11-06	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
US5688938A (en) *	1991-08-23	1997-11-18	The Brigham & Women's Hospital, Inc.	Calcium receptor-active molecules
US5858684A (en) *	1991-08-23	1999-01-12	The Brigham And Women's Hospital, Inc.	Method of screening calcium receptor-active molecules
US6031003A (en) *	1991-08-23	2000-02-29	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
US6011068A (en) *	1991-08-23	2000-01-04	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
WO1993019774A1 (en) *	1992-04-03	1993-10-14	Amylin Pharmaceuticals, Inc.	Amylin and possibly insulin containing composition for the treatment of anorexia and related states
US5962314A (en) *	1993-02-23	1999-10-05	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
ES2285707T3 (es)	1994-10-21	2007-11-16	Nps Pharmaceuticals, Inc.	Compuestos activos frente al receptor de calcio.
WO1997041090A1 (en)	1996-05-01	1997-11-06	Nps Pharmaceuticals, Inc.	Inorganic ion receptor-active compounds
DE69836689D1 (de)	1997-09-26	2007-02-01	Auckland Uniservices Ltd	Verwendung von Amylin, Adrenomedullin und deren Analoga zur Behandlung von Knorpeldefekten

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4925833A (en) *	1983-12-29	1990-05-15	The Research Foundation Of State University Of New York	Use of tetracycline to enhance bone protein synthesis and/or treatment of osteoporosis
GB8407907D0 (en) *	1984-03-27	1984-05-02	Sandoz Ltd	Organic compounds
US4588716A (en) *	1984-05-04	1986-05-13	Wisconsin Alumni Research Foundation	Method for treating metabolic bone disease in mammals
JPS62129297A (ja) *	1985-08-09	1987-06-11	Toyo Jozo Co Ltd	カルシトニン遺伝子関連ペプチド誘導体
US4677132A (en) *	1986-03-12	1987-06-30	American Home Products Corporation	Inhibition of bone resorption by etodolac
GB8720115D0 (en) *	1987-08-26	1987-09-30	Cooper G J S	Treatment of diabetes mellitus
HU203198B (en) *	1987-10-26	1991-06-28	Sandoz Ag	Process for producing pharmaceutical compositions having immunity-inhibiting, monokin-, particularly interleukin-1-inhibiting effect
EP0425565B1 (de) *	1988-07-22	1994-09-21	Ethyl Corporation	Siliziumverbindungen zur behandlung von knochen

1989
- 1989-07-08 GB GB898915712A patent/GB8915712D0/en active Pending
1990
- 1990-07-07 WO PCT/US1990/003841 patent/WO1991000710A1/en not_active Ceased
- 1990-07-07 JP JP2510582A patent/JPH04500691A/ja active Pending
- 1990-07-09 IE IE249490A patent/IE62625B1/en not_active IP Right Cessation
- 1990-07-09 AT AT90307471T patent/ATE137975T1/de not_active IP Right Cessation
- 1990-07-09 SG SG1996003975A patent/SG46382A1/en unknown
- 1990-07-09 CA CA002020752A patent/CA2020752C/en not_active Expired - Lifetime
- 1990-07-09 EP EP90307471A patent/EP0408284B1/de not_active Expired - Lifetime
- 1990-07-09 ES ES90307471T patent/ES2088971T3/es not_active Expired - Lifetime
- 1990-07-09 DK DK90307471.4T patent/DK0408284T3/da active
- 1990-07-09 DE DE69026986T patent/DE69026986T2/de not_active Expired - Lifetime
1991
- 1991-03-07 DK DK040191A patent/DK40191A/da not_active Application Discontinuation
1996
- 1996-07-31 GR GR960402038T patent/GR3020680T3/el unknown

Also Published As

Publication number	Publication date
DK0408284T3 (da)	1996-06-03
ES2088971T3 (es)	1996-10-01
CA2020752A1 (en)	1992-01-10
EP0408284B1 (de)	1996-05-15
SG46382A1 (en)	1998-02-20
DE69026986T2 (de)	1996-10-02
DE69026986D1 (de)	1996-06-20
IE62625B1 (en)	1995-02-22
GB8915712D0 (en)	1989-08-31
EP0408284A3 (en)	1992-01-08
CA2020752C (en)	1996-12-24
DK40191D0 (da)	1991-03-07
EP0408284A2 (de)	1991-01-16
GR3020680T3 (en)	1996-10-31
JPH04500691A (ja)	1992-02-06
DK40191A (da)	1991-03-07
WO1991000710A1 (en)	1991-01-24
IE902494A1 (en)	1991-02-13

Legal Events

Date	Code	Title	Description
2010-10-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE137975T1 (de)	1996-06-15	Amylin zur behandlung von knochenleiden
IS2132B (is)	2006-08-15	Notkun á estrogeni til framleiðslu á lyfi til meðhöndlunar vegna tíðahvarfa
DE59101613D1 (de)	1994-06-16	Knochennagel zur Versorgung von Oberarmfrakturen.
DK408089D0 (da)	1989-08-18	Proteiner
ATE76294T1 (de)	1992-06-15	Galanthamin oder dessen analoge zur behandlung der alzheimerschen krankheit.
AU1808488A (en)	1988-12-06	Compounds for the treatment of alzheimer's disease
ITFI910071V0 (it)	1991-06-25	Piastra per osso per la porzione distale dell'omero
GB2193102B (en)	1990-03-21	Fracture brace
ZA887721B (en)	1990-05-30	Substituted tetralins,chromans and related compounds in the treatment of asthma,arthiritis and related diseases
GB8621816D0 (en)	1986-10-15	Therapeutic composition
JPS6471889A (en)	1989-03-16	Novel 6-acyl-(6h)-dibenzo(c,e)(1,2)oxaphosphorine- 6-oxide, manufacture and use as photoinitiator
FI971127A0 (fi)	1997-03-18	2,4-diaminopyrimidiini-3-oksidin tai jonkin sen suolan käyttö kollageenin kypsymis- ja rakentumishäiriöiden hoitamiseen
MY103790A (en)	1993-09-30	Novel compound for the treatment of several bone affecting diseases
ATE107859T1 (de)	1994-07-15	Verwendung von antiprogestomimetika zur stimulierung des eisprungs.
HU9301726D0 (en)	1993-10-28	Compounds and preparatives hindering resorption of bones
EP0330756A3 (en)	1989-11-29	Thienotricyclics for the treatment of bronchial diseases
EP0358438A3 (de)	1991-10-09	Ethansulfonamid-Derivate
IL132354A0 (en)	2001-03-19	Use of cartilage oligomeric matrix protein for the treatment of rheumatoid arthritis
EP0295827A3 (de)	1989-04-12	Verwendung von 24,25-Dihydroxycholecalciferol bei der Heilung von Knochenbrüchen
DE69915852D1 (de)	2004-04-29	Lhrh-analoga zur behandlung der osteoporose
EP0173527A3 (de)	1988-02-03	Insulin-selektive Somatostatin-Analoge
DE3776662D1 (de)	1992-03-19	Pharmazeutische zusammensetzungen zur behandlung von hyperproliferativer hautkrankheit.
ES2015772A6 (es)	1990-09-01	Procedimiento e obtencion de nuevos derivados del 5-fluorouracilo, concretamente los n1-acil-sustituidos-n3-orto-toluil-5-fluorouracilo.