ATE138364T1 - Hemmungsstoff für aldosereduktase - Google Patents

Hemmungsstoff für aldosereduktase

Info

Publication number: ATE138364T1
Authority: AT; Austria
Prior art keywords: reductase inhibitor; aldose reductase; different; chem; carrier
Prior art date: 1990-08-08

Application number

AT91307304T

Other languages

English (en)

Inventor

Yukio Suzuki

Kouichi Kuno

Motoshi Shoda

Masao Yaso

Satoshi Yaginuma

Akira Asahi

Original Assignee

Asahi Chemical Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-08

Filing date

1991-08-08

Publication date

1996-06-15

1991-08-08 Application filed by Asahi Chemical Ind filed Critical Asahi Chemical Ind

1996-06-15 Application granted granted Critical

1996-06-15 Publication of ATE138364T1 publication Critical patent/ATE138364T1/de

Links

229940118148 Aldose reductase inhibitor Drugs 0.000 title abstract 2
239000003288 aldose reductase inhibitor Substances 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004210 cyclohexylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
MNQZXJOMYWMBOU-UHFFFAOYSA-N glyceraldehyde Chemical compound OCC(O)C=O MNQZXJOMYWMBOU-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Ophthalmology & Optometry (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Plant Substances (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT91307304T 1990-08-08 1991-08-08 Hemmungsstoff für aldosereduktase ATE138364T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2208128A JPH0495025A (ja)	1990-08-08	1990-08-08	アルドースリダクターゼ阻害剤

Publications (1)

Publication Number	Publication Date
ATE138364T1 true ATE138364T1 (de)	1996-06-15

Family

ID=16551106

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91307304T ATE138364T1 (de)	1990-08-08	1991-08-08	Hemmungsstoff für aldosereduktase

Country Status (6)

Country	Link
US (1)	US5155259A (de)
EP (1)	EP0473308B1 (de)
JP (1)	JPH0495025A (de)
AT (1)	ATE138364T1 (de)
DE (1)	DE69119668T2 (de)
ES (1)	ES2087247T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU676235B2 (en) *	1992-10-26	1997-03-06	Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The	Intrinsic inhibitors of aldose reductase
US6376546B1 (en)	1997-10-14	2002-04-23	Asahi Kasei Kabushiki Kaisha	Biphenyl-5-alkanoic acid derivatives and use thereof
US6867320B2 (en) *	2002-02-21	2005-03-15	Asahi Kasei Pharma Corporation	Substituted phenylalkanoic acid derivatives and use thereof
CA2535665A1 (en) *	2003-08-14	2005-02-24	Asahi Kasei Pharma Corporation	Substituted arylalkanoic acid derivative and use thereof
JP5137834B2 (ja)	2006-07-20	2013-02-06	旭化成ファーマ株式会社	置換フェニルアルカン酸の新規結晶及び製造方法
EP2848252A3 (de) *	2007-03-23	2015-06-17	The Board of Regents of the University of Texas System	Aldose-Reduktase-Inhibitoren zur Behandlung von Uveitis
HRP20221430T1 (hr)	2010-07-16	2023-01-06	The Trustees Of Columbia University In The City Of New York	Inhibitori aldozoreduktaze i njihova uporaba
US8916563B2 (en)	2010-07-16	2014-12-23	The Trustees Of Columbia University In The City Of New York	Aldose reductase inhibitors and uses thereof
RS61239B1 (sr)	2016-06-21	2021-01-29	Univ Columbia	Inhibitori aldozne reduktaze i postupci korišćenja
IL272246B2 (en)	2017-07-28	2026-01-01	Applied Therapeutics Inc	History of 2-(4-oxo/thioketone/azo-3-((substituted)benzo[d]thiazol-2-yl)methyl)- 3,4-dihydrothieno[3,4-d]pyridazin-1-yl)acetic acid for use as an aldose reductase inhibitor for the treatment of galactosemia or prevention of galactosemia-related complications
CA3132136A1 (en)	2019-04-01	2020-10-08	Andrew Wasmuth	Inhibitors of aldose reductase
JP2022531466A (ja)	2019-05-07	2022-07-06	ユニバーシティオブマイアミ	遺伝性ニューロパチーおよび関連障害の処置および検出
WO2021222165A1 (en)	2020-05-01	2021-11-04	Applied Therapeutics, Inc.	Aldose reductase inhibitors for treating sorbitol dehydrogenase deficiency

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS62205095A (ja) *	1986-03-04	1987-09-09	Toyo Jozo Co Ltd	新生理活性物質アルドスタチンおよびその製造法

1990
- 1990-08-08 JP JP2208128A patent/JPH0495025A/ja active Pending
1991
- 1991-08-08 EP EP91307304A patent/EP0473308B1/de not_active Expired - Lifetime
- 1991-08-08 ES ES91307304T patent/ES2087247T3/es not_active Expired - Lifetime
- 1991-08-08 US US07/742,352 patent/US5155259A/en not_active Expired - Fee Related
- 1991-08-08 AT AT91307304T patent/ATE138364T1/de not_active IP Right Cessation
- 1991-08-08 DE DE69119668T patent/DE69119668T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0473308A1 (de)	1992-03-04
DE69119668D1 (de)	1996-06-27
DE69119668T2 (de)	1997-01-02
EP0473308B1 (de)	1996-05-22
JPH0495025A (ja)	1992-03-27
ES2087247T3 (es)	1996-07-16
US5155259A (en)	1992-10-13

Legal Events

Date	Code	Title	Description
1996-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
AU3621689A (en)	1989-09-28	Carbamate compounds, compositions, and method of making the same
CA2264824A1 (en)	1999-01-14	A process for preparing 2-amino malonic acid derivatives and 2-amino-1,3-propanediol derivatives, and intermediates for preparing the same
DK345989D0 (da)	1989-07-12	Quinolinderivater
ATE138364T1 (de)	1996-06-15	Hemmungsstoff für aldosereduktase
IL93443A0 (en)	1990-11-29	Trifluoromethylphenylazolyl-methyloxirane derivatives and fungicides containing these compounds
FI952101A0 (fi)	1995-05-03	Merkaptanfoerening
ATE137220T1 (de)	1996-05-15	Benzen-, pyridin-, pyrimidinderivat
ES2173087T3 (es)	2002-10-16	Compuesto de azetidinona y procedimiento para su preparacion.
DK0784055T3 (da)	2003-06-02	Pyrimidinylpyrazolderivater
ES2046229T3 (es)	1994-02-01	Composicion antiulcerosa.
DE69121259D1 (de)	1996-09-19	Beta-Lactam-Verbindungen und ihre Herstellung
MX9701949A (es)	1997-06-28	Derivados de distamicina substituidos con bis-(2-haloetil) aminofenilo como agentes antitumorales y antivirales.
ES2188481T3 (es)	2003-07-01	Derivados de polinalbufina.
ES2093091T3 (es)	1996-12-16	Derivado de glutation.
EP0760362A4 (de)	1999-09-01	Neue diaminomethyliden-derivate
KR950704333A (ko)	1995-11-17	신규한 세펨 유도체(novel cephem derivatives)
DK0601191T3 (da)	1999-04-26	Hidtil ukendt tetracyklisk forbindelse
DE69629133D1 (de)	2003-08-21	Substituierte Aminochinazolinon (thion) Derivate
EP0407621A4 (en)	1991-10-02	Benzothiazole derivatives
ES2089097T3 (es)	1996-10-01	Procedimiento para la fabricacion de derivados de bencilftalacinona y sales de la misma.
NO913768D0 (no)	1991-09-25	Forbindelse, anvendelse og fremstilling.
ES2116508T3 (es)	1998-07-16	Procedimiento para la preparacion de 2-perfluoroalquil-3-oxazolin-5-ona.
FI883507A0 (fi)	1988-07-26	Naftotiazepinderivat och deras framstaellning.
ES2040223T3 (es)	1993-10-16	Derivados de la tiadiazolilacetamida, procedimiento para su fabricacion y su utilizacion.
ES2077697T3 (es)	1995-12-01	Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.