ATE138645T1 - Indan-derivate als thromboxan-antagonisten - Google Patents

Indan-derivate als thromboxan-antagonisten

Info

Publication number: ATE138645T1
Authority: AT; Austria
Prior art keywords: integer; similar; thromboxane; optionally substituted; indane derivatives
Prior art date: 1991-03-01

Application number

AT92906203T

Other languages

English (en)

Inventor

Kiyoshi Yoshida

Yoshiaki Yamaji

Tadashi Kurimoto

Ryuichi Sato

Motoki Torizuka

Original Assignee

Zeria Pharm Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-03-01

Filing date

1992-02-28

Publication date

1996-06-15

1992-02-28 Application filed by Zeria Pharm Co Ltd filed Critical Zeria Pharm Co Ltd

1996-06-15 Application granted granted Critical

1996-06-15 Publication of ATE138645T1 publication Critical patent/ATE138645T1/de

Links

239000005557 antagonist Substances 0.000 title 1
150000002468 indanes Chemical class 0.000 title 1
RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 title 1
DSNBHJFQCNUKMA-SCKDECHMSA-N thromboxane A2 Chemical compound OC(=O)CCC\C=C/C[C@@H]1[C@@H](/C=C/[C@@H](O)CCCCC)O[C@@H]2O[C@H]1C2 DSNBHJFQCNUKMA-SCKDECHMSA-N 0.000 abstract 2
125000006539 C12 alkyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
239000005977 Ethylene Substances 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
-1 angiosis Chemical compound 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000036461 convulsion Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
PQNFLJBBNBOBRQ-UHFFFAOYSA-N indane Chemical class C1=CC=C2CCCC2=C1 PQNFLJBBNBOBRQ-UHFFFAOYSA-N 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000005704 oxymethylene group Chemical group [H]C([H])([*:2])O[*:1] 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000005504 styryl group Chemical group 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
230000002792 vascular Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/12—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
- C07C311/13—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/17—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
- C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/42—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Immunology (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Zoology (AREA)
Heart & Thoracic Surgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT92906203T 1991-03-01 1992-02-28 Indan-derivate als thromboxan-antagonisten ATE138645T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP5761991		1991-03-01

Publications (1)

Publication Number	Publication Date
ATE138645T1 true ATE138645T1 (de)	1996-06-15

Family

ID=13060895

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92906203T ATE138645T1 (de)	1991-03-01	1992-02-28	Indan-derivate als thromboxan-antagonisten

Country Status (12)

Country	Link
US (1)	US5409956A (de)
EP (1)	EP0589037B1 (de)
JP (1)	JP2558208B2 (de)
KR (1)	KR0184701B1 (de)
AT (1)	ATE138645T1 (de)
AU (1)	AU651182B2 (de)
CA (1)	CA2105067C (de)
DE (1)	DE69211133T2 (de)
DK (1)	DK0589037T3 (de)
ES (1)	ES2090611T3 (de)
GR (1)	GR3020106T3 (de)
WO (1)	WO1992015558A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2099743A1 (en) *	1992-07-02	1994-01-03	Akihiko Ishida	Pyridazinone derivatives and processes for preparing the same
US5739132A (en) *	1992-07-02	1998-04-14	Tanabe Seiyaku Co., Ltd.	Pyridazinone derivatives and processes for preparing the same
CA2138812A1 (en) *	1993-12-28	1995-06-29	Akihiko Ishida	Indane derivative and processes for preparing the same
US6017953A (en) *	1993-12-28	2000-01-25	Allergan Sales, Inc.	Thromboxane ligands
CA2139088A1 (en) *	1993-12-28	1995-06-29	Akihiko Ishida	Indane derivatives, processes for preparing the same and synthetic intermediate of the same
JPH0859458A (ja) *	1994-08-25	1996-03-05	Zeria Pharmaceut Co Ltd	インダン誘導体を含有する高脂血症治療剤
US5670504A (en) *	1995-02-23	1997-09-23	Merck & Co. Inc.	2,6-diaryl pyridazinones with immunosuppressant activity
IL118631A (en) *	1995-06-27	2002-05-23	Tanabe Seiyaku Co	History of pyridazinone and processes for their preparation
DE19604191A1 (de) *	1996-02-06	1997-08-07	Hoechst Schering Agrevo Gmbh	2,4-Diamino-1,3,5-triazine, Verfahren zu deren Herstellung und deren Verwendung als Herbizide und Pflanzenwachstumsregulatoren
ES2300119T3 (es)	1997-02-27	2008-06-01	Takeda Pharmaceutical Company Limited	Compuestos de amina, su produccion y su uso como inhibidores de la produccion de beta-amiloide.
FR2760235B1 (fr) *	1997-02-28	1999-04-09	Adir	Nouveaux derives de benzenesulfonylamine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN100349872C (zh)	2000-04-03	2007-11-21	武田药品工业株式会社	制备胺衍生物的方法
AU2001271718A1 (en) *	2000-06-29	2002-01-14	Smith Kline Beecham Corporation	Fatty acid synthase inhibitors
DE10229180A1 (de) *	2002-06-28	2004-01-29	Aventis Pharma Deutschland Gmbh	Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen
CN103539709B (zh) *	2013-03-22	2015-11-25	湖北生物医药产业技术研究院有限公司	N-(-1-氢-茚-1-基)磺酰胺类化合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3623944A1 (de) *	1986-07-16	1988-02-11	Thomae Gmbh Dr K	Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US5190975A (en) *	1987-11-18	1993-03-02	Tanabe Seiyaku Co., Ltd.	Indan derivatives used for treating thromboses or asthma
IL88314A (en) *	1987-11-18	1994-05-30	Tanabe Seiyaku Co	Sulphonylamino indane derivatives, their preparation and pharmaceutical compositions containing them
FR2645537B1 (fr) *	1989-04-05	1994-03-04	Fabre Medicament Pierre	Nouveaux sulfonamides derives d'acides benzocycliques ou benzoheterocycliques, leur preparation et leur application en therapeutique

1992
- 1992-02-28 DK DK92906203.2T patent/DK0589037T3/da active
- 1992-02-28 WO PCT/JP1992/000236 patent/WO1992015558A1/ja not_active Ceased
- 1992-02-28 JP JP4506077A patent/JP2558208B2/ja not_active Expired - Fee Related
- 1992-02-28 AU AU13384/92A patent/AU651182B2/en not_active Ceased
- 1992-02-28 EP EP92906203A patent/EP0589037B1/de not_active Expired - Lifetime
- 1992-02-28 DE DE69211133T patent/DE69211133T2/de not_active Expired - Fee Related
- 1992-02-28 AT AT92906203T patent/ATE138645T1/de not_active IP Right Cessation
- 1992-02-28 ES ES92906203T patent/ES2090611T3/es not_active Expired - Lifetime
- 1992-02-28 US US08/107,823 patent/US5409956A/en not_active Expired - Fee Related
- 1992-02-28 CA CA002105067A patent/CA2105067C/en not_active Expired - Fee Related
1993
- 1993-08-26 KR KR1019930702565A patent/KR0184701B1/ko not_active Expired - Fee Related
1996
- 1996-05-31 GR GR950403455T patent/GR3020106T3/el unknown

Also Published As

Publication number	Publication date
KR0184701B1 (en)	1999-05-15
CA2105067C (en)	2002-05-14
GR3020106T3 (en)	1996-08-31
JPH06510787A (ja)	1994-12-01
US5409956A (en)	1995-04-25
WO1992015558A1 (fr)	1992-09-17
EP0589037A1 (de)	1994-03-30
AU1338492A (en)	1992-10-06
ES2090611T3 (es)	1996-10-16
EP0589037B1 (de)	1996-05-29
AU651182B2 (en)	1994-07-14
KR930703249A (ko)	1993-11-29
DK0589037T3 (da)	1996-09-16
JP2558208B2 (ja)	1996-11-27
DE69211133D1 (en)	1996-07-04
EP0589037A4 (de)	1994-04-27
CA2105067A1 (en)	1992-09-02
DE69211133T2 (de)	1996-10-31

Legal Events

Date	Code	Title	Description
1996-11-15	UEP	Publication of translation of european patent specification
2006-11-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE138645T1 (de)	1996-06-15	Indan-derivate als thromboxan-antagonisten
FI104172B1 (fi)	1999-11-30	Herbisidiset 4-bentsoyyli-isoksatsolijohdannaiset
ES2092580T3 (es)	1996-12-01	Derivado de 2-ariltiazol y composicion farmaceutica que contiene el mismo.
ES2091834T3 (es)	1996-11-16	Compuestos aromaticos.
IL95975A0 (en)	1991-07-18	Benzimidazole derivatives,their production and use
DK0475577T3 (da)	1994-04-25	Hydrogenerede rapamycinderivater
FR2364198A1 (fr)	1978-04-07	Nouveaux produits a action herbicide, derives d'acides phenoxyvaleriques
DE69406323D1 (de)	1997-11-27	Substituierte Aminsäure Derivate verwendbar für die Behandlung von Arteriosclerosis
RU93058626A (ru)	1996-04-27	Пиридинсульфонамид, способ его получения и применения, промежуточный продукт для его синтеза и способ его получения
EP1314719A4 (de)	2005-09-21	Benzoesäurederivate und medikamente die diese als aktiven wirkstoff enthalten
DK1057814T3 (da)	2005-07-04	Tetrahydrobenzindolderivater
BG96682A (bg)	1993-12-24	Метод за получаване на циклохексанови и тетрахидропиранови производни
ATE332641T1 (de)	2006-08-15	Iod-propylenglycol-zitzentauchbad
DE69319859D1 (de)	1998-08-27	Neue tetracyclische verbindungen
IS3855A (is)	1992-11-08	Aðferð til framleiðslu nýs sýkladrepandi efnasambands Thiomarinol, fengið með ræktun Alteromanas rava SANK 73390
ATE73795T1 (de)	1992-04-15	Thioformamid-derivate.
DE3484375D1 (de)	1991-05-08	Pharmazeutische zusammenstellung fuer die prophylaxe oder behandlung von tierhaltungsketose.
GR1001566B (el)	1994-05-31	Μέ?οδος παρασκευής νέων παραγώγων βενζοφουρανυλιμιδαζόλης.
ATE327238T1 (de)	2006-06-15	Pkb-3564-substanz mit die gefässneubildung hemmender wirkung
EP0606481A4 (de)	1994-11-09	Herbizid, das ein zyklisches hexapeptid als aktiven inhaltsstoff enthält.
TH58174A3 (th)	2003-09-10	เบนโซไพแรนอะนาลอกที่ถูกแทนที่สำหรับรักษาอาการอักเสบ
FR2374032A2 (fr)	1978-07-13	Nouveaux acides carboxyliques derives de l'indane
BG29270A3 (en)	1980-10-15	Herbicide means and method for weeds fighting
GT199400033A (es)	1995-11-02	Compuestos antibacteriales (derivados de cefalosporina)
KR940021526A (ko)	1994-10-19	카르복실산 유도체