ATE138915T1 - 1,2-dihydro-2-oxoquinoxalinderivate, deren herstellung und verwendung in der therapie - Google Patents

1,2-dihydro-2-oxoquinoxalinderivate, deren herstellung und verwendung in der therapie

Info

Publication number: ATE138915T1
Authority: AT; Austria
Prior art keywords: radical; group; alkyl; branched; straight
Prior art date: 1989-10-23

Application number

AT90916034T

Other languages

English (en)

Inventor

Guy Pitet

Christian Faure

Francoise Couret

Dennis Bigg

Jean-Pierre Tarayre

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-23

Filing date

1990-10-17

Publication date

1996-06-15

1990-10-17 Application filed by Pf Medicament filed Critical Pf Medicament

1996-06-15 Application granted granted Critical

1996-06-15 Publication of ATE138915T1 publication Critical patent/ATE138915T1/de

Links

FFRYUAVNPBUEIC-UHFFFAOYSA-N quinoxalin-2-ol Chemical class C1=CC=CC2=NC(O)=CN=C21 FFRYUAVNPBUEIC-UHFFFAOYSA-N 0.000 title abstract 2
238000002560 therapeutic procedure Methods 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
125000005843 halogen group Chemical group 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
101100516554 Caenorhabditis elegans nhr-5 gene Proteins 0.000 abstract 1
101100079984 Caenorhabditis elegans nhr-9 gene Proteins 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000005518 carboxamido group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
150000002825 nitriles Chemical group 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
208000023504 respiratory system disease Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT90916034T 1989-10-23 1990-10-17 1,2-dihydro-2-oxoquinoxalinderivate, deren herstellung und verwendung in der therapie ATE138915T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8913961A FR2653430B1 (fr)	1989-10-23	1989-10-23	Nouveaux derives de dihydro-1,2 oxo-2 quinoxalines, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number	Publication Date
ATE138915T1 true ATE138915T1 (de)	1996-06-15

Family

ID=9386749

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90916034T ATE138915T1 (de)	1989-10-23	1990-10-17	1,2-dihydro-2-oxoquinoxalinderivate, deren herstellung und verwendung in der therapie

Country Status (10)

Country	Link
US (1)	US5198441A (de)
EP (1)	EP0450039B1 (de)
JP (1)	JPH04502475A (de)
AT (1)	ATE138915T1 (de)
DE (1)	DE69027300T2 (de)
DK (1)	DK0450039T3 (de)
ES (1)	ES2087917T3 (de)
FR (1)	FR2653430B1 (de)
GR (1)	GR3020392T3 (de)
WO (1)	WO1991005772A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2696456B1 (fr) *	1992-10-07	1995-01-06	Pf Medicament	Dérivés de dihydro-1,2 oxo amino-3 quinoxalines, leur préparation et leur application en thérapeutique.
US6690251B2 (en) *	2001-04-11	2004-02-10	Kyocera Wireless Corporation	Tunable ferro-electric filter
EP2247580B1 (de)	2008-03-05	2015-07-08	Merck Patent GmbH	Chinoxalinonderivate als insulinausscheidungsstimulatoren, verfahren zu ihrer gewinnung und ihre verwendung zur behandlung von diabetes
ES2913051T3 (es)	2015-12-24	2022-05-31	Univ California	Reguladores de CFTR y métodos de uso de los mismos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA728649A (en) *		1966-02-22	Donau-Pharmazie Gesellschaft M.B.H.	Dihydroquinoxalone-(2) derivatives and process of preparing same
CH624395A5 (de) *	1976-01-08	1981-07-31	Ciba Geigy Ag
US4181724A (en) *	1978-09-11	1980-01-01	The Upjohn Company	Quinoxalinone compounds useful for expanding the lumina or air passages in mammals
EP0032564A1 (de) *	1979-12-28	1981-07-29	Medichemie Ag	Pharmazeutische Verwendung von Caroverin und/oder Caroverinsalzen sowie Caroverinsalze mit Xanthinderivat-Säureresten und Nicotinsäurerest
JPS572277A (en) *	1980-06-07	1982-01-07	Nissan Chem Ind Ltd	Quinoxalinone derivative, its preparation, and fungicide for agricultural and horticultural use
JPS62198671A (ja) *	1986-02-25	1987-09-02	Toyo Jozo Co Ltd	１−置換アルキル１，２−ジヒドロ−２−ピラジノン誘導体
US5034537A (en) *	1988-09-23	1991-07-23	Smithkline Beecham Corporation	Leukotriene antagonists

1989
- 1989-10-23 FR FR8913961A patent/FR2653430B1/fr not_active Expired - Fee Related
1990
- 1990-10-17 AT AT90916034T patent/ATE138915T1/de not_active IP Right Cessation
- 1990-10-17 WO PCT/FR1990/000752 patent/WO1991005772A1/fr not_active Ceased
- 1990-10-17 DK DK90916034.3T patent/DK0450039T3/da active
- 1990-10-17 JP JP2514792A patent/JPH04502475A/ja active Pending
- 1990-10-17 US US07/688,536 patent/US5198441A/en not_active Expired - Fee Related
- 1990-10-17 ES ES90916034T patent/ES2087917T3/es not_active Expired - Lifetime
- 1990-10-17 DE DE69027300T patent/DE69027300T2/de not_active Expired - Fee Related
- 1990-10-17 EP EP90916034A patent/EP0450039B1/de not_active Expired - Lifetime
1996
- 1996-06-28 GR GR960401761T patent/GR3020392T3/el unknown

Also Published As

Publication number	Publication date
US5198441A (en)	1993-03-30
WO1991005772A1 (fr)	1991-05-02
FR2653430A1 (fr)	1991-04-26
ES2087917T3 (es)	1996-08-01
JPH04502475A (ja)	1992-05-07
DE69027300T2 (de)	1997-01-23
DE69027300D1 (de)	1996-07-11
DK0450039T3 (da)	1996-10-07
GR3020392T3 (en)	1996-09-30
EP0450039A1 (de)	1991-10-09
FR2653430B1 (fr)	1991-12-20
EP0450039B1 (de)	1996-06-05

Similar Documents

Publication	Publication Date	Title
FI925255A0 (fi)	1992-11-19	Aromatiska amino-alkoholderivat med egenskaper som motverkar sockersjuka och fetma, deras framstaellning och terapeutiska anvaendningar
HRP20031098B1 (en)	2012-03-31	Beta-amino tetrahydroimidazo (1,2-a) pyrazines and tetrahydrotrioazolo (4,3-a) pyrazines as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
DE60311821D1 (de)	2007-03-29	Dibenzylaminverbindung und deren medizinische verwendung
DE69014901D1 (de)	1995-01-19	Muscarin-rezeptor-antagonisten.
AR035069A1 (es)	2004-04-14	Compuestos inhibidores de espiropirimidin-2,4,6-triona metaloproteinasas, composicion farmaceutica, procedimiento de tratamiento
ATE356624T1 (de)	2007-04-15	Phenoxypropanolamin-derivate, ihre herstellung und therapeutische verwendung
NO20030471L (no)	2003-03-28	Karboksamidforbindelser og deres anvendelse som antagonister for en 11CBY-reseptor
ATE283268T1 (de)	2004-12-15	2-adamantylethylamine und deren verwendung bei der behandlung von abnormalitäten in der glutamat transmission
BR9306221A (pt)	1998-06-30	Derivados do acilaminoindol como agonistas 5-htl
BR0015195A (pt)	2002-06-18	Composto, composição farmacêutica, uso de um composto, e, métodos para o tratamento de uma condição associada com a transmissão reduzida de nicotina para o tratamento ou profilaxia de distúrbios psicóticos ou distúrbios de deterioração intelectual e para o tratamento ou profilaxia de doenças ou condições humanas
NO940558L (de)	1994-08-22
NZ334701A (en)	2001-01-26	Dihydropyrones and use in treating retrovirus infections and diseases
ATE138915T1 (de)	1996-06-15	1,2-dihydro-2-oxoquinoxalinderivate, deren herstellung und verwendung in der therapie
ZA889023B (en)	1989-08-30	2-(piperazinyl)-2-oxoethylene substituted flavonoid derivatives,processes for preparing them and pharmaceutical compositions containing them
FI923759A0 (fi)	1992-08-20	Terapeutiska bensazapinfoereningar.
ATE181734T1 (de)	1999-07-15	N-benzoylmethylsubstituierte paroxetinderivate
ATE278676T1 (de)	2004-10-15	Imdazol-derivate, deren herstellung und deren verwendung als s-adenosylmethionin decarboxylase (=samdc) inhibitoren
ATE236634T1 (de)	2003-04-15	Verwendung von 4-piperidinmethanolderivaten zur behandlung von neuralentwicklungsstörungen
ES479110A1 (es)	1979-07-01	Procedimiento para preparar derivados de benzamidina.
ID26809A (id)	2001-02-08	Senyawa-senyawa turunan sianoiminokuinoksalin
ATE19881T1 (de)	1986-06-15	Tropyl- und pseudotropylalkylbenzoate und ihre verwendung in der behandlung von migraene.
DK608586D0 (da)	1986-12-17	Polysubstituerede pyridin-1-oxider og fysiologisk aktive salte deraf, deres fremstilling og anvendelse som laegemidler
DE68903893D1 (de)	1993-01-28	20,21-dinoreburnamenin-derivate, substituiert in position 15 durch eine aminogruppe und deren salze, verfahren zu deren herstellung und die auf diese weise erhaltenen zwischenverbindungen, deren anwendung als arzneimittel und diese enthaltende pharmazeutische zusammensetzungen.
SE8007121L (sv)	1981-04-12	Oxyohimbankarboxylsyra derivat

Legal Events

Date	Code	Title	Description
1997-01-15	UEP	Publication of translation of european patent specification
2000-07-15	REN	Ceased due to non-payment of the annual fee