DK0450039T3 - Hidtil ukendte derivater af 1,2-dihydro-2-oxoquinoxalin, deres fremstilling og terapeutiske anvendelse - Google Patents

Hidtil ukendte derivater af 1,2-dihydro-2-oxoquinoxalin, deres fremstilling og terapeutiske anvendelse

Info

Publication number: DK0450039T3
Authority: DK; Denmark
Prior art keywords: radical; group; alkyl; branched; straight
Prior art date: 1989-10-23

Application number

DK90916034.3T

Other languages

English (en)

Inventor

Guy Pitet

Christian Faure

Francoise Couret

Dennis Bigg

Jean-Pierre Tarayre

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-23

Filing date

1990-10-17

Publication date

1996-10-07

1990-10-17 Application filed by Pf Medicament filed Critical Pf Medicament

1996-10-07 Application granted granted Critical

1996-10-07 Publication of DK0450039T3 publication Critical patent/DK0450039T3/da

Links

FFRYUAVNPBUEIC-UHFFFAOYSA-N quinoxalin-2-ol Chemical class C1=CC=CC2=NC(O)=CN=C21 FFRYUAVNPBUEIC-UHFFFAOYSA-N 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
125000005843 halogen group Chemical group 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
101100516554 Caenorhabditis elegans nhr-5 gene Proteins 0.000 abstract 1
101100079984 Caenorhabditis elegans nhr-9 gene Proteins 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000005518 carboxamido group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
150000002825 nitriles Chemical group 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
208000023504 respiratory system disease Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Pulmonology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK90916034.3T 1989-10-23 1990-10-17 Hidtil ukendte derivater af 1,2-dihydro-2-oxoquinoxalin, deres fremstilling og terapeutiske anvendelse DK0450039T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8913961A FR2653430B1 (fr)	1989-10-23	1989-10-23	Nouveaux derives de dihydro-1,2 oxo-2 quinoxalines, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number	Publication Date
DK0450039T3 true DK0450039T3 (da)	1996-10-07

Family

ID=9386749

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90916034.3T DK0450039T3 (da)	1989-10-23	1990-10-17	Hidtil ukendte derivater af 1,2-dihydro-2-oxoquinoxalin, deres fremstilling og terapeutiske anvendelse

Country Status (10)

Country	Link
US (1)	US5198441A (da)
EP (1)	EP0450039B1 (da)
JP (1)	JPH04502475A (da)
AT (1)	ATE138915T1 (da)
DE (1)	DE69027300T2 (da)
DK (1)	DK0450039T3 (da)
ES (1)	ES2087917T3 (da)
FR (1)	FR2653430B1 (da)
GR (1)	GR3020392T3 (da)
WO (1)	WO1991005772A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2696456B1 (fr) *	1992-10-07	1995-01-06	Pf Medicament	Dérivés de dihydro-1,2 oxo amino-3 quinoxalines, leur préparation et leur application en thérapeutique.
US6690251B2 (en) *	2001-04-11	2004-02-10	Kyocera Wireless Corporation	Tunable ferro-electric filter
ES2548583T3 (es)	2008-03-05	2015-10-19	Merck Patent Gmbh	Derivados de quinoxalinona como estimuladores de la secreción de insulina, métodos para su obtención y su uso para el tratamiento de la diabetes
RU2730855C2 (ru)	2015-12-24	2020-08-26	Дзе Риджентс Оф Дзе Юниверсити Оф Калифорниа	Кфтр регуляторы и способы их применения

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA728649A (en) *		1966-02-22	Donau-Pharmazie Gesellschaft M.B.H.	Dihydroquinoxalone-(2) derivatives and process of preparing same
CH624395A5 (da) *	1976-01-08	1981-07-31	Ciba Geigy Ag
US4181724A (en) *	1978-09-11	1980-01-01	The Upjohn Company	Quinoxalinone compounds useful for expanding the lumina or air passages in mammals
EP0032564A1 (de) *	1979-12-28	1981-07-29	Medichemie Ag	Pharmazeutische Verwendung von Caroverin und/oder Caroverinsalzen sowie Caroverinsalze mit Xanthinderivat-Säureresten und Nicotinsäurerest
JPS572277A (en) *	1980-06-07	1982-01-07	Nissan Chem Ind Ltd	Quinoxalinone derivative, its preparation, and fungicide for agricultural and horticultural use
JPS62198671A (ja) *	1986-02-25	1987-09-02	Toyo Jozo Co Ltd	１−置換アルキル１，２−ジヒドロ−２−ピラジノン誘導体
US5034537A (en) *	1988-09-23	1991-07-23	Smithkline Beecham Corporation	Leukotriene antagonists

1989
- 1989-10-23 FR FR8913961A patent/FR2653430B1/fr not_active Expired - Fee Related
1990
- 1990-10-17 ES ES90916034T patent/ES2087917T3/es not_active Expired - Lifetime
- 1990-10-17 WO PCT/FR1990/000752 patent/WO1991005772A1/fr not_active Ceased
- 1990-10-17 DK DK90916034.3T patent/DK0450039T3/da active
- 1990-10-17 US US07/688,536 patent/US5198441A/en not_active Expired - Fee Related
- 1990-10-17 AT AT90916034T patent/ATE138915T1/de not_active IP Right Cessation
- 1990-10-17 EP EP90916034A patent/EP0450039B1/fr not_active Expired - Lifetime
- 1990-10-17 DE DE69027300T patent/DE69027300T2/de not_active Expired - Fee Related
- 1990-10-17 JP JP2514792A patent/JPH04502475A/ja active Pending
1996
- 1996-06-28 GR GR960401761T patent/GR3020392T3/el unknown

Also Published As

Publication number	Publication date
DE69027300D1 (de)	1996-07-11
ES2087917T3 (es)	1996-08-01
EP0450039B1 (fr)	1996-06-05
ATE138915T1 (de)	1996-06-15
US5198441A (en)	1993-03-30
DE69027300T2 (de)	1997-01-23
GR3020392T3 (en)	1996-09-30
JPH04502475A (ja)	1992-05-07
FR2653430A1 (fr)	1991-04-26
FR2653430B1 (fr)	1991-12-20
EP0450039A1 (fr)	1991-10-09
WO1991005772A1 (fr)	1991-05-02

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