ATE138941T1 - Kovalente kupplung von makromolekülen an substratoberflächen - Google Patents

Kovalente kupplung von makromolekülen an substratoberflächen

Info

Publication number
ATE138941T1
ATE138941T1 AT90303256T AT90303256T ATE138941T1 AT E138941 T1 ATE138941 T1 AT E138941T1 AT 90303256 T AT90303256 T AT 90303256T AT 90303256 T AT90303256 T AT 90303256T AT E138941 T1 ATE138941 T1 AT E138941T1
Authority
AT
Austria
Prior art keywords
macromolecules
substrate surfaces
covalent coupling
polystyrene
hydroymethyl
Prior art date
Application number
AT90303256T
Other languages
English (en)
Inventor
David Okrongly
Original Assignee
Applied Immunesciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Immunesciences filed Critical Applied Immunesciences
Application granted granted Critical
Publication of ATE138941T1 publication Critical patent/ATE138941T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Formation Of Insulating Films (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
AT90303256T 1989-03-29 1990-03-27 Kovalente kupplung von makromolekülen an substratoberflächen ATE138941T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/330,207 US4933410A (en) 1989-03-29 1989-03-29 Covalent attachment of macromolecules on substrate surfaces

Publications (1)

Publication Number Publication Date
ATE138941T1 true ATE138941T1 (de) 1996-06-15

Family

ID=23288752

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90303256T ATE138941T1 (de) 1989-03-29 1990-03-27 Kovalente kupplung von makromolekülen an substratoberflächen

Country Status (10)

Country Link
US (1) US4933410A (de)
EP (1) EP0390500B1 (de)
JP (1) JPH0618914B2 (de)
AT (1) ATE138941T1 (de)
CA (1) CA1323729C (de)
DE (1) DE69027248T2 (de)
DK (1) DK0390500T3 (de)
ES (1) ES2090094T3 (de)
GR (1) GR3020959T3 (de)
SG (1) SG64314A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5241012A (en) * 1987-05-19 1993-08-31 Applied Immune Sciences, Inc. Activated and conjugated polystyrene substrate
US5286789A (en) * 1989-05-26 1994-02-15 Applied Immune Sciences, Inc. Solid phase multiple peptide synthesis
JPH0372496A (ja) * 1989-05-26 1991-03-27 Applied Immune Sci Inc 固相多重ペプチド合成
US6143508A (en) * 1989-06-29 2000-11-07 Rhone-Poulenc Rorer Pharmaceuticals Inc. Device and process for cell capture and recovery
CA1340565C (en) 1989-06-29 1999-05-25 Thomas B. Okarma Device and process for cell capture and recovery
US5556748A (en) * 1991-07-30 1996-09-17 Xenopore Corporation Methods of sandwich hybridization for the quantitative analysis of oligonucleotides
US5424219A (en) * 1991-10-25 1995-06-13 Cytech Biomedical, Inc. Method of performing assays for biomolecules and solid supports for use in such methods
AU724089B2 (en) * 1996-12-05 2000-09-14 Idego Aps Sensor laminates and multi-sectioned fluid delivery devices for detecting by immunoassay target molecules in biological fluids
US6391655B1 (en) * 1997-07-30 2002-05-21 Corning Incorporated Oxidized styrenic polymers for DNA binding
GB9925016D0 (en) * 1999-10-23 1999-12-22 Univ Sheffield Binding surface
US6376723B2 (en) 1999-12-29 2002-04-23 Shell Oil Company Process for the carbonylation of formaldehyde
ES2262601T3 (es) * 2001-07-16 2006-12-01 Dr. Chip Biotechnology Inc. Inmobilizacion de biomoleculas.
US6995248B2 (en) 2001-07-16 2006-02-07 Dr. Chip Biotechnology, Inc. Immobilization of nucleic acids
JP2005506839A (ja) * 2001-10-02 2005-03-10 ベクトン・ディキンソン・アンド・カンパニー 細胞外マトリックスおよび他の分子を使用する幹細胞の増殖および分化
US6926823B2 (en) * 2002-06-03 2005-08-09 Varian, Inc. Polymer with superior polar retention for sample pretreatment
US20040062882A1 (en) * 2002-09-30 2004-04-01 Andrea Liebmann-Vinson Cell adhesion resisting surfaces
US8172395B2 (en) * 2002-12-03 2012-05-08 Novartis Ag Medical devices having antimicrobial coatings thereon
CN100584879C (zh) * 2007-05-15 2010-01-27 中国科学院长春应用化学研究所 一种咪唑改性的苯乙烯型大孔吸附树脂的制备方法
GR1009057B (el) 2014-06-03 2017-06-23 Ευαγγελος Μιχαηλ Γογγολιδης Μεθοδος παρασκευης χημικα σταθερων υποστρωματων με εγχαραξη πλασματος για απευθειας ομοιοπολικη ακινητοποιηση βιομοριων

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4081329A (en) * 1972-12-08 1978-03-28 Boehringer Mannheim Gmbh Preparation of carrier-bound macromolecular compounds
US3956219A (en) * 1973-02-01 1976-05-11 Eli Lilly And Company Crosslinked polystyrene and substituted polystyrene compositions
US3875114A (en) * 1973-06-18 1975-04-01 Gen Electric Amidomethylene modified aromatic carbocyclic polymers and methods for making the same
IL43366A (en) * 1973-10-04 1976-09-30 Yeda Res & Dev Production of organic reagents for the acylation of organic compounds
US3995094A (en) * 1975-09-12 1976-11-30 Dynapol Corporation Halomethylation of polystyrene
CA1083508A (fr) * 1975-11-13 1980-08-12 Jacques Grange Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique
US4226958A (en) * 1979-08-27 1980-10-07 The Upjohn Company Process for preparing organo-arsenic derivatives of polystyrene and related polymers
CA1204667A (en) * 1982-10-04 1986-05-20 Masashi Kodama Blood treating material
DE3311889A1 (de) * 1983-03-31 1984-10-11 Byk-Mallinckrodt Chemische Produkte Gmbh, 6057 Dietzenbach Verfahren zur irreversiblen bindung von protein an polystyroloberflaechen unter erhaltung der biologischen aktivitaet, so erhaltene polystyroloberflaechen und ihre verwendung
EP0134307B1 (de) * 1983-07-29 1989-04-19 Henning Berlin GmbH Chemie und Pharmawerk Voraktivierte Kunststoffoberflächen zur Immobilisierung von organisch-chemischen und biologischen Materialien, Verfahren zur Herstellung und Verwendung derselben
FR2582815B1 (fr) * 1985-05-31 1989-04-07 Commissariat Energie Atomique Procede de separation des anticorps antifacteur viii : c, utilisable notamment pour l'epuration du plasma sanguin d'un hemophile de type a
US5241012A (en) * 1987-05-19 1993-08-31 Applied Immune Sciences, Inc. Activated and conjugated polystyrene substrate
IT1216745B (it) * 1988-02-11 1990-03-08 Montedipe Spa Processo per immidizzare copolimeri vinil aromatici.

Also Published As

Publication number Publication date
CA1323729C (en) 1993-10-26
JPH0618914B2 (ja) 1994-03-16
DE69027248D1 (de) 1996-07-11
JPH02261833A (ja) 1990-10-24
US4933410A (en) 1990-06-12
GR3020959T3 (en) 1996-12-31
DE69027248T2 (de) 1996-10-02
ES2090094T3 (es) 1996-10-16
SG64314A1 (en) 2000-06-20
EP0390500B1 (de) 1996-06-05
DK0390500T3 (da) 1996-06-24
EP0390500A3 (de) 1992-07-15
EP0390500A2 (de) 1990-10-03

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Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee